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Genomes and Genes | Cholesterol CenterSummaryOrganization: Cholesterol Center Country: USA Top Publications
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High factor XI, recurrent pregnancy loss, enoxaparin
Charles J Glueck
Cholesterol Center, Jewish Hospital, Cincinnati, Ohio 45229, USA
Fertil Steril 94:2828-31. 2010..Three of the 5 women with high factor XI and recurrent pregnancy loss, with 19 previous pregnancy losses and 0 live births, were given enoxaparin during 5 subsequent pregnancies, and had 6 term live births and 1 miscarriage...Microscopic computed tomography imaging of the cerebral circulation in mice: feasibility and pitfalls
T Abruzzo
Department of Radiology, University of Cincinnati Medical Center, Cincinnati, Ohio 45267 0762, USA
Synapse 62:557-65. 2008..Micro CT of the murine COW using a high-throughput image processing model is feasible. Angioarchitectural distortion due to volume averaging and thresholding effect can occur and pathological findings should be confirmed...Repeat bronchoalveolar lavage to guide antibiotic duration for ventilator-associated pneumonia
Eric W Mueller
Department of Pharmacy Services, The University Hospital, Cincinnati, Ohio, USA
J Trauma 63:1329-37; discussion 1337. 2007..We sought to determine whether antibiotic duration for VAP can be safely abbreviated in trauma patients using repeat bronchoalveolar lavage (BAL)...Association between the T-786C eNOS polymorphism and idiopathic osteonecrosis of the head of the femur
Charles J Glueck
Cholesterol Center, Jewish Hospital of Cincinnati, 3200 Burnet Avenue, Cincinnati, OH 45229, USA
J Bone Joint Surg Am 89:2460-8. 2007..We studied relationships between the T-786C eNOS polymorphism and idiopathic and secondary necrosis of the head of the femur in order to better understand the pathophysiology of osteonecrosis...Deep tissue injury
Mary Arnold Long
Drake Center, Cinncinnati, OH, USA
Rehabil Nurs 32:135, 150. 2007Comparison of outcomes after (123)I versus (131)I pre-ablation imaging before radioiodine ablation in differentiated thyroid carcinoma
Edward B Silberstein
Division of Nuclear Medicine, Department of Radiology, University of Cincinnati Medical Center, Cincinnati, Ohio 45219, USA
J Nucl Med 48:1043-6. 2007....Metformin before and during pregnancy and lactation in polycystic ovary syndrome
Charles J Glueck
Jewish Hospital, Cholesterol Center, ABC Building, Cincinnati, OH, USA
Expert Opin Drug Saf 6:191-8. 2007..Systematic studies have not yet been done assessing how hyperinsulinemia, polycystic ovary syndrome and metformin may affect lactation...Stromelysin-1 5A/6A and eNOS T-786C polymorphisms, MTHFR C677T and A1298C mutations, and cigarette-cannabis smoking: a pilot, hypothesis-generating study of gene-environment pathophysiological associations with Buerger's disease
Charles J Glueck
Cholesterol Center, Jewish Hospital, Cincinnati, Ohio 45229, USA
Clin Appl Thromb Hemost 12:427-39. 2006..Further blinded, placebo-controlled studies are needed to determine whether our observations can be generalized to larger BD cohorts...Metformin-diet ameliorates coronary heart disease risk factors and facilitates resumption of regular menses in adolescents with polycystic ovary syndrome
C J Glueck
Cholesterol Center, Jewish Hospital, Cincinnati, OH 45229, USA
J Pediatr Endocrinol Metab 19:831-42. 2006..8 kg/m2, we assessed effeicacy of metformin-diet for 1 year for reduction of weight, insulin, HOMA insulin resistance (IR), cholesterol, triglycerides, and resumption of regular menses...The Magnet Recognition Program and evidence-based practice
Martha L Clark
the St Luke Hospitals, 85 North Grand Avenue, Ft Thomas, KY 41075, USA
J Perianesth Nurs 21:186-9. 2006..This article will give a brief introduction of the Magnet Recognition Program and suggest activities that will involve staff nurses in EBP...Growth, motor, and social development in breast- and formula-fed infants of metformin-treated women with polycystic ovary syndrome
Charles J Glueck
Cholesterol Center, Jewish Hospital, Cincinnati, Ohio 45229, USA
J Pediatr 148:628-632. 2006..To test the hypothesis that metformin during lactation versus formula feeding would have no adverse effects on infants' growth, motor-social development, or intercurrent illness...Response to diet and metformin in women with idiopathic intracranial hypertension with and without concurrent polycystic ovary syndrome or hyperinsulinemia
Charles J Glueck
Cholesterol Center, Jewish Hospital, Cincinnati, Ohio, USA
MedGenMed 7:41. 2005Obesity, free testosterone, and cardiovascular risk factors in adolescents with polycystic ovary syndrome and regularly cycling adolescents
Charles J Glueck
Cholesterol Center, Alliance Hospitals, Cincinnati, OH 45229, USA
Metabolism 55:508-14. 2006....Plasminogen activator inhibitor activity, 4G5G polymorphism of the plasminogen activator inhibitor 1 gene, and first-trimester miscarriage in women with polycystic ovary syndrome
Charles J Glueck
Cholesterol Center, Jewish Hospital, MDL Laboratories, Cincinnati, OH 45229, USA
Metabolism 55:345-52. 2006..Preconception and first-trimester decrements in PAI-1 activity on Glucophage are associated with live births, whereas increments or no change in PAI-1 activity despite Glucophage appears to be associated with first-trimester miscarriage...Thrombophilia, hypofibrinolysis, the eNOS T-786C polymorphism, and multifocal osteonecrosis
Charles J Glueck
Cholesterol Center, Jewish Hospital of Cincinnati, Cincinnati, OH 45229, USA
J Bone Joint Surg Am 90:2220-9. 2008....Innovative solutions: the effect of a workshop on reducing the experience of moral distress in an intensive care unit setting
Catherine M Beumer
Jewish Hospital, 4777 East Galbraith Rd, Cincinnati, OH 45236, USA
Dimens Crit Care Nurs 27:263-7. 2008..This article discusses the workshop and its effect on participants' coping with moral distress...The revitalization of a business office: how one system increased its self-pay collections
Doug Gardner
Patient Financial Services, Health Alliance, Cincinnati, USA
Healthc Financ Manage 61:80-2, 84. 2007..The organization was able to achieve this increase without any decrease in patient satisfaction...Negative pressure wound therapy overlay technique with collagen dressings for nonhealing wounds
Mary Arnold-Long
Drake Center, Cincinnati, Ohio 45216, USA
J Wound Ostomy Continence Nurs 37:549-53. 2010....Palliative high-dose-rate endobronchial brachytherapy for recurrent carcinoma: the University of Louisville experience
Jessica N Guarnaschelli
Department of Radiation Oncology, University of Cincinnati College of Medicine, Cincinnati, OH 45267 0757, USA
J Palliat Med 13:981-9. 2010..To determine the efficacy and toxicity of iridium-192 high-dose-rate (HDR) endobronchial brachytherapy (EBBT) for symptomatic palliation of respiratory symptoms caused by endobronchial carcinoma...Endothelial nitric oxide synthase T-786C mutation, a reversible etiology of Prinzmetal's angina pectoris
Charles J Glueck
Cholesterol Center, Jewish Hospital of Cincinnati, Cincinnati, Ohio, USA
Am J Cardiol 105:792-6. 2010..001). In conclusion, the eNOS T-786C mutation appears to be a reversible etiology of Prinzmetal's variant angina in white Americans whose angina might be ameliorated by l-arginine...T-786C polymorphism of the endothelial nitric oxide synthase gene and neuralgia-inducing cavitational osteonecrosis of the jaws
Charles J Glueck
Cholesterol Center, Jewish Hospital of Cincinnati, Cincinnati, Ohio, USA
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 109:548-53. 2010....Where there is blood, there is a way: unusual collateral vessels in superior and inferior vena cava obstruction
Sangita Kapur
Department of Radiology, University of Cincinnati Medical Center, 234 Goodman Street, Cincinnati, OH 45267 0761, USA
Radiographics 30:67-78. 2010..An understanding of these unusual collateral pathways is essential in a patient with caval occlusion who presents with signs and symptoms of a right-to-left shunt or has unusual enhancing lesions in the liver...Successful implementation of intelligent infusion technology in a multihospital setting: nursing perspective
Lisa Longshore
Jewish Hospital of Cincinnati, 4777 E Galbraith Rd, Cincinnati, OH 45236, USA
J Infus Nurs 33:38-47. 2010..Also described are the ongoing educational efforts, lessons learned, and specific results in intercepting significant medication administration errors...Metformin-diet ameliorates coronary heart disease risk factors and facilitates resumption of regular menses in adolescents with polycystic ovary syndrome
Charles J Glueck
Jewish Hospital, Cholesterol Center, ABC Building, 3200 Burnet Ave, Cincinnati, OH 45229, USA
J Pediatr Endocrinol Metab 22:815-26. 2009..In 20 adolescents age < or = 17 (16 +/- 1 yr) with polycystic ovary syndrome (PCOS), we assessed efficacy and safety of metformin-diet for 1 year in treatment of endocrinopathy and coronary heart disease (CHD) risk factors...Cysts within and adjacent to the lesser tuberosity and their association with rotator cuff abnormalities
Robert D Wissman
Department of Radiology, University of Cincinnati Medical Center, Cincinnati, OH 45267 0761, USA
AJR Am J Roentgenol 193:1603-6. 2009..The purpose of our study was to determine the incidence of cysts in and adjacent to the lesser tuberosity and their association with rotator cuff abnormalities and subcoracoid impingement...Acute knee dislocation: review of an elusive entity
Sangita Kapur
Department of Radiology, University of Cincinnati Medical Center, Cincinnati, Ohio 45267 0761, USA
Curr Probl Diagn Radiol 38:237-50. 2009..The purpose of this article is to review the epidemiology of knee dislocations, important imaging findings, and the most common complications...Lifelong learning in the 21st century and beyond
Jannette Collins
Department of Radiology, University of Wisconsin Hospital and Clinics, E3 311 Clinical Science Center, Madison, WI 53792 3252, USA
Radiographics 29:613-22. 2009....Extensor mechanism injuries in tibiofemoral dislocations
Robert D Wissman
Department of Radiology, University of Cincinnati Medical Center, Cincinnati, OH 45267 0761, USA
J Comput Assist Tomogr 33:145-9. 2009..The purpose of this study is to evaluate the incidence, location, and associated findings of extensor mechanism injuries in the setting of tibiofemoral knee dislocations...Should high creatine kinase discourage the initiation or continuance of statins for the treatment of hypercholesterolemia?
Charles J Glueck
Cholesterol Center, Jewish Hospital, Cincinnati, OH 45229, USA
Metabolism 58:233-8. 2009..High pretreatment CK, particularly 1 to 5 times the UNL, should not be an impediment to start or continue statins to lower LDLC...Epidemiology, pathophysiology, and initial management of chronic immune thrombocytopenic purpura
Jane Pruemer
University of Cincinnati College of Pharmacy, 3225 Eden Avenue, Cincinnati, OH 45267 0004, USA
Am J Health Syst Pharm 66:S4-10. 2009..In addition, the recommendations of two expert panels for the management of ITP are summarized...Hyperglycemia in the critically ill patient
Michelle M Gearhart
Department of Pharmacy Services, University Hospital, Cincinnati, OH 45219, USA
AACN Clin Issues 17:50-5. 2006....Controlling the usage of intranasal mupirocin does impact the rate of Staphylococcus aureus deep sternal wound infections in cardiac surgery patients
Mary R Nicholson
Epidemiology Department, The Christ Hospital, Cincinnati, OH 45219, USA
Am J Infect Control 34:44-8. 2006..8% per 100 procedures performed. In an attempt to reduce S aureus sternal wound infections, the use of prophylactic intranasal mupirocin was examined...Metformin therapy throughout pregnancy reduces the development of gestational diabetes in women with polycystic ovary syndrome
C J Glueck
Cholesterol Center, Jewish Hospital, Cincinnati, Ohio 45229, USA
Fertil Steril 77:520-5. 2002..To assess whether metformin safely reduced development of gestational diabetes in women with the polycystic ovary syndrome (PCOS)...Secretin for the treatment of autism
Joanna M McQueen
Ambulatory Services, University Hospital, Health Alliance, Cincinnati, OH, USA
Ann Pharmacother 36:305-11. 2002..To evaluate the role of secretin in the treatment of children with autism...Strategies to minimize immunological and nonimmunological risk factors in the renal transplant population
M R First
Department of Internal Medicine, University of Cincinnati Medical Center, Ohio 45267 0585, USA
Transplantation 72:S20-4. 2001..The advantageous effects of tacrolimus on both immunological and nonimmunological risk factors offer potential benefits for long-term graft function and survival...Metformin to restore normal menses in oligo-amenorrheic teenage girls with polycystic ovary syndrome (PCOS)
C J Glueck
Cholesterol Center, Jewish Hospital and Molecular Diagnostics Laboratories, Cincinnati, Ohio 45229, USA
J Adolesc Health 29:160-9. 2001..To describe our clinical experience in using Metformin combined with a high protein-low carbohydrate diet to restore normal menstrual cycles in teenaged females with polycystic ovary syndrome (PCOS)...Conceptual database modeling: a method for enabling end users (radiologists) to understand and develop their information management applications
H Hawkins
Department of Radiology, University Hospital, Cincinnati, OH 45219, USA
J Digit Imaging 14:195-6. 2001..This presentation describes conceptual database modeling, using object role modeling, as a means by which end-users (clinicians) may participate in database development...Conceptual database modeling for understanding and developing information management applications
H H Hawkins
Department of Radiology, University Hospital, 234 Goodman St, Mail Location 0761, Cincinnati, OH 45219, USA
Radiographics 21:781-7. 2001..Increasing the amount of clinical and management input in the development process may help information systems better meet user needs, become accepted and more often used, and ultimately succeed...Serum concentrations of cefuroxime after continuous infusion in coronary bypass graft patients
S E Pass
Department of Pharmacy Services, University Hospital, Cincinnati, OH 45219 2316, USA
Ann Pharmacother 35:409-13. 2001....Polycystic ovary syndrome, infertility, familial thrombophilia, familial hypofibrinolysis, recurrent loss of in vitro fertilized embryos, and miscarriage
C J Glueck
Cholesterol Center, Jewish Hospital, Cincinnati, Ohio 45299, USA
Fertil Steril 74:394-7. 2000..To study reversible determinants of infertility and recurrent loss of transferred embryos after failure of 7 of 10 embryo transfers, 1 live birth, and 2 miscarriages...Diseases of the hepatopulmonary axis
C A Meyer
Departments of Radiology and Medicine, University of Cincinnati, 234 Goodman St, ML 0742, Cincinnati, OH 45219 2316, USA
Radiographics 20:687-98. 2000..Knowledge of these associations will assist the radiologist in forming a meaningful differential diagnosis and may influence treatment decisions...Effect of exogenous estrogen on atherothrombotic vascular disease risk related to the presence or absence of the factor V Leiden mutation (resistance to activated protein C)
C J Glueck
Cholesterol Center, Jewish Hospital, Cincinnati, Ohio 45229, USA HYPERLINK
Am J Cardiol 84:549-54. 1999..A second, much larger group of women will also be identified without the factor V Leiden mutation (96%), in whom ERT may reduce the risk for atherothrombosis...Time course, magnitude, and consistency of platelet inhibition by abciximab, tirofiban, or eptifibatide in patients with unstable angina pectoris undergoing percutaneous coronary intervention
D J Kereiakes
Carl and Edyth Lindner Center for Clinical Cardiovascular Research, Cincinnati, Ohio 45219, USA
Am J Cardiol 84:391-5. 1999....Efficacy of abciximab induced platelet blockade using a rapid point of care assay
D J Kereiakes
The Carl and Edyth Lindner Research Center for Clinical Cardiovascular Research, Cincinnati, Ohio 45219, USA
J Thromb Thrombolysis 7:265-76. 1999..The utility of this device to optimize therapy with platelet glycoprotein IIb/IIIa inhibitors is currently being evaluated...Dietary amino acids as new and novel agents to enhance allograft survival
J W Alexander
Department of Surgery, University of Cincinnati Medical Center, Ohio 45267 0558, USA
Nutrition 15:130-4. 1999..6 +/- 32.3 d [mean +/- SEM] versus 20.1 +/- 3.2 d for control). It is concluded that both arginine and glutamine enhance the immunosuppressive effects of donor-specific transfusion and cyclosporine...Current and emerging therapy for primary pulmonary hypertension
Steven E Pass
College of Pharmacy, University of Cincinnati, OH, USA
Ann Pharmacother 36:1414-23. 2002..To review the epidemiology, pathophysiology, clinical symptoms, and diagnostic workup of primary pulmonary hypertension (PPH) and to discuss the available data on the current and emerging therapies being used to treat this disorder...Pregnancy outcomes among women with polycystic ovary syndrome treated with metformin
Charles J Glueck
Cholesterol Center, Jewish Hospital, ABC Building, 3200 Burnet Avenue, Cincinnati, OH 45229, USA
Hum Reprod 17:2858-64. 2002....The contentious nature of gestational diabetes: diet, insulin, glyburide and metformin
Charles J Glueck
Cholesterol Center, ABC Building, Jewish Hospital of Cincinnati, 3200 Burnet Avenue, Cincinnati, OH 45229, USA
Expert Opin Pharmacother 3:1557-68. 2002..Recent studies suggest that glyburide may be efficaciously substituted for insulin. Preliminary studies suggest that metformin may have the unique potential to prevent the development of GD...The factor V Leiden mutation, high factor VIII, and high plasminogen activator inhibitor activity: etiologies for sporadic miscarriage
Charles J Glueck
Cholesterol Center, Department of Medicine, Jewish Hospital of Cincinnati, Cincinnati, OH 45229, USA
Metabolism 54:1345-9. 2005..05) in measures of thrombophilia and hypofibrinolysis. After unexplained sporadic first trimester miscarriage, we suggest that measurements be done of the FV mutation, PAI-Fx, and factor VIII, etiologies for sporadic miscarriage...Rationale for having a chief pharmacy officer in a health care organization
Marianne F Ivey
Health Alliance, 3200 Burnet Avenue, Cincinnati, OH 45229, USA
Am J Health Syst Pharm 62:975-8. 2005Ramifications of four concurrent thrombophilic mutations and one hypofibrinolytic mutation
Charles J Glueck
Cholesterol Center, Jewish Hospital, Cincinnati, Ohio, USA
Clin Appl Thromb Hemost 10:365-71. 2004..Beyond aspirin, avoidance of exogenous estrogens, and enoxaparin prophylaxis during pregnancy, it is not known whether the proband's daughter should have lifelong anticoagulation therapy, or only after her first thrombotic event...Metformin, pre-eclampsia, and pregnancy outcomes in women with polycystic ovary syndrome
C J Glueck
Cholesterol Center, Jewish Hospital, Cincinnati, OH 45229, USA
Diabet Med 21:829-36. 2004..Was metformin during pregnancy in women with polycystic ovary syndrome (PCOS) associated with pre-eclampsia, and was it safe for mother and neonate?..Discontinuation and reinstitution of medications during the perioperative period
Steven E Pass
Department of Pharmacy Services, University Hospital, Cincinnati, OH 45219 2316, USA
Am J Health Syst Pharm 61:899-912; quiz 913-4. 2004....Height, weight, and motor-social development during the first 18 months of life in 126 infants born to 109 mothers with polycystic ovary syndrome who conceived on and continued metformin through pregnancy
C J Glueck
Cholesterol Center, ABC Building, 3200 Burnet Avenue, Cincinnati, OH 45229, USA
Hum Reprod 19:1323-30. 2004..5-2.55 g/day) through pregnancy...Efficacy of brachytherapy for prostate cancer in African Americans compared with Caucasians
William L Barrett
Division of Radiation Oncology, University of Cincinnati, Cincinnati, OH 45267 0757, USA
Brachytherapy 3:30-3. 2004..To compare the biochemical response to prostate brachytherapy between African Americans and Caucasians in a consecutive series of patients treated at a single institution...Metformin during pregnancy reduces insulin, insulin resistance, insulin secretion, weight, testosterone and development of gestational diabetes: prospective longitudinal assessment of women with polycystic ovary syndrome from preconception throughout preg
C J Glueck
Cholesterol Center, Jewish Hospital, Cincinnati, OH 45229, USA
Hum Reprod 19:510-21. 2004..We assessed the hypothesis that diet-metformin (MET) lessens the physiological gestational increase in IR and reduces gestational weight gain, thus reducing GD...Role of thrombosis in osteonecrosis
C J Glueck
Cholesterol Center, ABC Building, 3200 Burnet Avenue, Cincinnati, OH 45229, USA
Curr Hematol Rep 2:417-22. 2003..Placebo-controlled trials with a 2-year follow-up or longer in adults will be required to assess the promise of the pilot anticoagulant studies in osteonecrosis...Pioglitazone and metformin in obese women with polycystic ovary syndrome not optimally responsive to metformin
Charles J Glueck
Cholesterol Center, Jewish Hospital, ABC Building, 3200 Burnet Avenue, Cincinnati, OH 45229, USA
Hum Reprod 18:1618-25. 2003..We also compared these 13 women to 26 women with PCOS, who were responsive to metformin diet, matched by age and by pre- treatment menstrual history and not different by obesity categories...Metformin and gestational diabetes
Charles J Glueck
Jewish Hospital Cholesterol Center, ABC Building, 3200 Burnet Avenue, Cincinnati, OH 45229, USA
Curr Diab Rep 3:303-12. 2003..We postulate that interventions that reduce insulin resistance and lower requirements for endogenous insulin secretion can preserve b-cell function and prevent the development of type 2 diabetes mellitus...Cardiovascular and medical ramifications of treatment of subclinical hypothyroidism
Charles J Glueck
Cholesterol Center Jewish Hospital, 3200 Burnet Avenue, Cincinnati, OH 45229, USA
Curr Atheroscler Rep 5:73-7. 2003....Prognostic factors and clinical outcomes in children and adolescents with metastatic rhabdomyosarcoma--a report from the Intergroup Rhabdomyosarcoma Study IV
John C Breneman
Children s Hospital Medical Center, Division of Radiation Oncology, Cincinnati, OH 45219 0757, USA
J Clin Oncol 21:78-84. 2003..To identify risk factors associated with outcomes in children with metastatic rhabdomyosarcoma (RMS) treated on the fourth Intergroup Rhabdomyosarcoma Study (IRS-IV)...Use of low-dose OKT3 as induction therapy in liver transplantation
J F Whiting
Department of Surgery, University of Cincinnati Medical Center, Ohio 45267 0558, USA
Transplantation 65:577-80. 1998..A pilot study was performed to prospectively evaluate the safety and efficacy of "low-dose" OKT3 induction after liver transplantation...