JOHN RASH

Summary

Affiliation: Colorado State University
Country: USA

Publications

  1. ncbi request reprint Heterotypic gap junctions at glutamatergic mixed synapses are abundant in goldfish brain
    J E Rash
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO, United States Program in Molecular, Cellular and Integrative Neurosciences, Colorado State University, Fort Collins, CO, United States Electronic address
    Neuroscience 285:166-93. 2015
  2. pmc Mixed Electrical-Chemical Synapses in Adult Rat Hippocampus are Primarily Glutamatergic and Coupled by Connexin-36
    Farid Hamzei-Sichani
    Department of Neurosurgery, Mount Sinai School of Medicine New York, NY, USA
    Front Neuroanat 6:13. 2012
  3. pmc Connexin composition in apposed gap junction hemiplaques revealed by matched double-replica freeze-fracture replica immunogold labeling
    John E Rash
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    J Membr Biol 245:333-44. 2012
  4. pmc Ultrastructural localization of connexins (Cx36, Cx43, Cx45), glutamate receptors and aquaporin-4 in rodent olfactory mucosa, olfactory nerve and olfactory bulb
    John E Rash
    Department of Biomedical Sciences, Colorado State University, Fort Collins, 80523, USA
    J Neurocytol 34:307-41. 2005
  5. pmc Identification of connexin36 in gap junctions between neurons in rodent locus coeruleus
    J E Rash
    Department of Biomedical Sciences, Colorado State University, Campus Delivery 1617, Fort Collins, CO 80523, USA
    Neuroscience 147:938-56. 2007
  6. pmc Connexin36 vs. connexin32, "miniature" neuronal gap junctions, and limited electrotonic coupling in rodent suprachiasmatic nucleus
    J E Rash
    Department of Biomedical Sciences, Colorado State University, Campus Delivery 1617, Fort Collins, CO 80523 1617, USA
    Neuroscience 149:350-71. 2007
  7. pmc Identification of cells expressing Cx43, Cx30, Cx26, Cx32 and Cx36 in gap junctions of rat brain and spinal cord
    J E Rash
    Department of Biomedical Sciences, Colorado State University, Fort Collins 80523, USA
    Cell Commun Adhes 8:315-20. 2001
  8. pmc Molecular disruptions of the panglial syncytium block potassium siphoning and axonal saltatory conduction: pertinence to neuromyelitis optica and other demyelinating diseases of the central nervous system
    J E Rash
    Department of Biomedical Sciences, Program in Neuronal Growth and Development, and Program in Cell and Molecular Biology, Campus Delivery 1617, Colorado State University, Fort Collins, CO 80523, USA
    Neuroscience 168:982-1008. 2010
  9. pmc Freeze-fracture and immunogold analysis of aquaporin-4 (AQP4) square arrays, with models of AQP4 lattice assembly
    J E Rash
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523 1617, USA
    Neuroscience 129:915-34. 2004
  10. pmc Abundance and ultrastructural diversity of neuronal gap junctions in the OFF and ON sublaminae of the inner plexiform layer of rat and mouse retina
    N Kamasawa
    Department of Biomedical Sciences, Colorado State University, Campus Delivery 1617, Fort Collins, CO 80523, USA
    Neuroscience 142:1093-117. 2006

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Heterotypic gap junctions at glutamatergic mixed synapses are abundant in goldfish brain
    J E Rash
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO, United States Program in Molecular, Cellular and Integrative Neurosciences, Colorado State University, Fort Collins, CO, United States Electronic address
    Neuroscience 285:166-93. 2015
    ....
  2. pmc Mixed Electrical-Chemical Synapses in Adult Rat Hippocampus are Primarily Glutamatergic and Coupled by Connexin-36
    Farid Hamzei-Sichani
    Department of Neurosurgery, Mount Sinai School of Medicine New York, NY, USA
    Front Neuroanat 6:13. 2012
    ..Cx36-containing gap junctions throughout hippocampus suggest the possibility of reciprocal modulation of electrical and chemical signals in diverse hippocampal neurons...
  3. pmc Connexin composition in apposed gap junction hemiplaques revealed by matched double-replica freeze-fracture replica immunogold labeling
    John E Rash
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523, USA
    J Membr Biol 245:333-44. 2012
    ..This approach allows unambiguous identification of connexins and determination of the membrane "sidedness" and the identities of connexin coupling partners in homotypic and heterotypic gap junctions of vertebrate neurons...
  4. pmc Ultrastructural localization of connexins (Cx36, Cx43, Cx45), glutamate receptors and aquaporin-4 in rodent olfactory mucosa, olfactory nerve and olfactory bulb
    John E Rash
    Department of Biomedical Sciences, Colorado State University, Fort Collins, 80523, USA
    J Neurocytol 34:307-41. 2005
    ....
  5. pmc Identification of connexin36 in gap junctions between neurons in rodent locus coeruleus
    J E Rash
    Department of Biomedical Sciences, Colorado State University, Campus Delivery 1617, Fort Collins, CO 80523, USA
    Neuroscience 147:938-56. 2007
    ....
  6. pmc Connexin36 vs. connexin32, "miniature" neuronal gap junctions, and limited electrotonic coupling in rodent suprachiasmatic nucleus
    J E Rash
    Department of Biomedical Sciences, Colorado State University, Campus Delivery 1617, Fort Collins, CO 80523 1617, USA
    Neuroscience 149:350-71. 2007
    ....
  7. pmc Identification of cells expressing Cx43, Cx30, Cx26, Cx32 and Cx36 in gap junctions of rat brain and spinal cord
    J E Rash
    Department of Biomedical Sciences, Colorado State University, Fort Collins 80523, USA
    Cell Commun Adhes 8:315-20. 2001
    ..Thus, in adult rat CNS, neurons and glia express different connexins, with "permissive" connexin pairing combinations apparently defining separate pathways for neuronal vs. glial gap junctional communication...
  8. pmc Molecular disruptions of the panglial syncytium block potassium siphoning and axonal saltatory conduction: pertinence to neuromyelitis optica and other demyelinating diseases of the central nervous system
    J E Rash
    Department of Biomedical Sciences, Program in Neuronal Growth and Development, and Program in Cell and Molecular Biology, Campus Delivery 1617, Colorado State University, Fort Collins, CO 80523, USA
    Neuroscience 168:982-1008. 2010
    ..Continued progress in molecular identification and subcellular mapping of glial ion and water channels will lead to a better understanding of demyelinating diseases of the CNS and to development of improved treatment regimens...
  9. pmc Freeze-fracture and immunogold analysis of aquaporin-4 (AQP4) square arrays, with models of AQP4 lattice assembly
    J E Rash
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523 1617, USA
    Neuroscience 129:915-34. 2004
    ..Several structural models are considered that incorporate freeze-fracture data for submolecular "cross-bridges" linking IMPs into the classical square lattices that characterize, in particular, naturally occurring AQP4...
  10. pmc Abundance and ultrastructural diversity of neuronal gap junctions in the OFF and ON sublaminae of the inner plexiform layer of rat and mouse retina
    N Kamasawa
    Department of Biomedical Sciences, Colorado State University, Campus Delivery 1617, Fort Collins, CO 80523, USA
    Neuroscience 142:1093-117. 2006
    ..ON sublamina...
  11. pmc Connexin-47 and connexin-32 in gap junctions of oligodendrocyte somata, myelin sheaths, paranodal loops and Schmidt-Lanterman incisures: implications for ionic homeostasis and potassium siphoning
    N Kamasawa
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO 80523 1617, USA
    Neuroscience 136:65-86. 2005
    ..Acting in series and in parallel, autologous and heterologous oligodendrocyte gap junctions provide essential pathways for intra- and intercellular ionic homeostasis...
  12. ncbi request reprint Grid-mapped freeze-fracture analysis of gap junctions in gray and white matter of adult rat central nervous system, with evidence for a "panglial syncytium" that is not coupled to neurons
    J E Rash
    Department of Anatomy and Neurobiology, Colorado State University, Fort Collins 80523, USA
    J Comp Neurol 388:265-92. 1997
    ....
  13. pmc Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord
    J E Rash
    Department of Anatomy and Neurobiology, Colorado State University, Fort Collins, CO 80523, USA
    Proc Natl Acad Sci U S A 95:11981-6. 1998
    ....
  14. ncbi request reprint Direct immunogold labeling of connexins and aquaporin-4 in freeze-fracture replicas of liver, brain, and spinal cord: factors limiting quantitative analysis
    J E Rash
    Department of Anatomy and Neurobiology, Colorado State University, Fort Collins 80523, USA
    Cell Tissue Res 296:307-21. 1999
    ....
  15. pmc Cell-specific expression of connexins and evidence of restricted gap junctional coupling between glial cells and between neurons
    J E Rash
    Department of Anatomy, Colorado State University, Fort Collins, Colorado 80523, USA
    J Neurosci 21:1983-2000. 2001
    ..Thus, the different cell types of the CNS express different connexins, which define separate pathways for neuronal versus glial gap junctional communication...
  16. pmc High-resolution proteomic mapping in the vertebrate central nervous system: close proximity of connexin35 to NMDA glutamate receptor clusters and co-localization of connexin36 with immunoreactivity for zonula occludens protein-1 (ZO-1)
    J E Rash
    Department of Biomedical Sciences, Colorado State University, Fort Collins, CO, USA
    J Neurocytol 33:131-51. 2004
    ..intermediate-range molecular interactions in the complex membrane appositions at synapses between neurons...
  17. ncbi request reprint Update on connexins and gap junctions in neurons and glia in the mammalian nervous system
    James I Nagy
    Department of Physiology, Faculty of Medicine, University of Manitoba, 730 William Avenue Winnipeg, Manitoba, Canada R3E 3J7
    Brain Res Brain Res Rev 47:191-215. 2004
    ....
  18. pmc Connexin45-containing neuronal gap junctions in rodent retina also contain connexin36 in both apposing hemiplaques, forming bihomotypic gap junctions, with scaffolding contributed by zonula occludens-1
    Xinbo Li
    Department of Physiology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada
    J Neurosci 28:9769-89. 2008
    ..These data document that in Cx45-expressing neurons of IPL, Cx45 is almost always accompanied by Cx36, forming "bihomotypic" gap junctions, with Cx45 structurally coupling to Cx45 and Cx36 coupling to Cx36...
  19. pmc Connexin29 and connexin32 at oligodendrocyte and astrocyte gap junctions and in myelin of the mouse central nervous system
    James I Nagy
    Department of Physiology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba R3E 3J7, Canada
    J Comp Neurol 464:356-70. 2003
    ....
  20. pmc Gap junctions on hippocampal mossy fiber axons demonstrated by thin-section electron microscopy and freeze fracture replica immunogold labeling
    Farid Hamzei-Sichani
    Program in Neural and Behavioral Science, State University of New York, Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA
    Proc Natl Acad Sci U S A 104:12548-53. 2007
    ....
  21. pmc Aquaporin-4 square array assembly: opposing actions of M1 and M23 isoforms
    C Sue Furman
    Department of Biomedical Sciences and Program in Molecular, Cellular, and Integrative Neurosciences, Colorado State University, Fort Collins, CO 80523, USA
    Proc Natl Acad Sci U S A 100:13609-14. 2003
    ..These studies show that M23 and M1 isoforms have opposing effects on intramembrane organization of AQP4: M23 forms large square arrays with abundant cross-bridges; M1 restricts square array assembly...
  22. pmc Astrocyte and oligodendrocyte connexins of the glial syncytium in relation to astrocyte anatomical domains and spatial buffering
    James I Nagy
    Department of Physiology, University of Manitoba, Winnipeg, Manitoba, Canada
    Cell Commun Adhes 10:401-6. 2003
    ....
  23. pmc Temporary loss of perivascular aquaporin-4 in neocortex after transient middle cerebral artery occlusion in mice
    Didrik S Frydenlund
    Nordic Centre of Excellence for Research in Water Imbalance Related Disorders WIRED, Centre for Molecular Biology and Neuroscience, Department of Anatomy, University of Oslo, P O Box 1105, 0317 Oslo, Norway
    Proc Natl Acad Sci U S A 103:13532-6. 2006
    ..These data indicate that the size of the AQP4 pool that controls the exchange of fluid between brain and blood during edema formation and dissolution is subject to large and region-specific changes in the reperfusion phase...
  24. pmc Connexin32-containing gap junctions in Schwann cells at the internodal zone of partial myelin compaction and in Schmidt-Lanterman incisures
    Carola Meier
    Department of Neuroanatomy and Molecular Brain Research, Ruhr University Bochum, 44801 Bochum, Germany
    J Neurosci 24:3186-98. 2004
    ....
  25. pmc Neuronal connexin36 association with zonula occludens-1 protein (ZO-1) in mouse brain and interaction with the first PDZ domain of ZO-1
    Xinbo Li
    Department of Physiology, Faculty of Medicine, University of Manitoba, 730 William Ave, Winnipeg, Manitoba, Canada R3E 3J7
    Eur J Neurosci 19:2132-46. 2004
    ..These results demonstrating a Cx36/ZO-1 association suggest a regulatory and/or scaffolding role of ZO-1 at gap junctions that form electrical synapses between neurons in mammalian brain...
  26. ncbi request reprint Dynamics of electrical transmission at club endings on the Mauthner cells
    Alberto E Pereda
    Department of Neuroscience, Albert Einstein College of Medicine, New York, USA
    Brain Res Brain Res Rev 47:227-44. 2004
    ..The widespread distribution of connexin35 and connexin36 and the ubiquity of some of the proposed regulatory elements suggest that other electrical synapses may be similarly regulated...

Research Grants4

  1. Zeiss LSM 510 Laser Scanning Microscope
    JOHN RASH; Fiscal Year: 2002
    ..The DIC Board of Directors will meet bi-monthly to insure continued efficient scheduling and operation of the replacement confocal microscope, to consider future upgrades, and to establish or change DIC access policies. ..
  2. Gap Junctions and Connexins in Developing CNS
    JOHN RASH; Fiscal Year: 2005
    ....
  3. Connexins in Neuronal and Glial Gap Junctions in the Central Nervous System
    JOHN RASH; Fiscal Year: 2007
    ..abstract_text> ..