Laura A Johnston

Summary

Affiliation: Columbia University
Country: USA

Publications

  1. pmc The proximate determinants of insect size
    Joseph Parker
    Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, 701 West 168th Street, New York, NY 10032, USA
    J Biol 5:15. 2006
  2. ncbi Control of compartment size by an EGF ligand from neighboring cells
    Joseph Parker
    Division of Cell Biology, Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, United Kingdom
    Curr Biol 16:2058-65. 2006
  3. doi Staphylinids
    Joseph Parker
    Department of Genetics and Development, Columbia University, New York, NY 10032, USA, and Division of Invertebrate Zoology, American Museum of Natural History, New York, NY 10024, USA Electronic address
    Curr Biol 27:R49-R51. 2017
  4. ncbi Jubogaster towai, a new Neotropical genus and species of Trogastrini (Coleoptera: Staphylinidae: Pselaphinae) exhibiting myrmecophily and extreme body enlargement
    Joseph Parker
    Department of Genetics and Development, Columbia University, 701 West 168th Street, New York, NY 10032, USA
    Zootaxa 3630:369-78. 2013
  5. doi Specialized myrmecophily at the ecological dawn of modern ants
    Joseph Parker
    Department of Genetics and Development, Columbia University, New York, NY 10032, USA Division of Invertebrate Zoology, American Museum of Natural History, New York, NY 10024, USA Electronic address
    Curr Biol 24:2428-34. 2014
  6. doi Morphogens, nutrients, and the basis of organ scaling
    Joseph Parker
    Department of Genetics and Development, Columbia University College of Physicians and Surgeons, 701 West 168th Street, New York, NY 10032, USA
    Evol Dev 13:304-14. 2011
  7. pmc Maintenance of imaginal disc plasticity and regenerative potential in Drosophila by p53
    Brent S Wells
    Department of Genetics and Development, Columbia University Medical Center, New York, NY 10032, USA
    Dev Biol 361:263-76. 2012
  8. pmc Compensatory proliferation in Drosophila imaginal discs requires Dronc-dependent p53 activity
    Brent S Wells
    Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Curr Biol 16:1606-15. 2006
  9. ncbi Drosophila myc regulates organ size by inducing cell competition
    Claire de la Cova
    Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, 701 West 168th Street, Room 704, New York, NY 10032, USA
    Cell 117:107-16. 2004
  10. pmc Activated STAT regulates growth and induces competitive interactions independently of Myc, Yorkie, Wingless and ribosome biogenesis
    Aloma B Rodrigues
    Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA
    Development 139:4051-61. 2012

Collaborators

  • Joseph Parker
  • Peter Gallant
  • Erika A Bach
  • Paola Bellosta
  • Claire de la Cova
  • Brent S Wells
  • D Christine Wu
  • Nanami Senoo-Matsuda
  • Marcello Ziosi
  • Aloma B Rodrigues
  • Simon de Beco
  • Ricardo M Neto-Silva
  • Elizabeth E Caygill
  • Catarina M Quinzii
  • Aidee Ayala-Camargo
  • Savraj Grewal
  • Michelle Krasny
  • Tamara Reyes-Robles
  • Tamara Zoranovic
  • Eri Yoshida
  • Mauricio Abril

Detail Information

Publications23

  1. pmc The proximate determinants of insect size
    Joseph Parker
    Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, 701 West 168th Street, New York, NY 10032, USA
    J Biol 5:15. 2006
    ..A new study employs a modeling approach to expose the factors that matter in the control of insect size...
  2. ncbi Control of compartment size by an EGF ligand from neighboring cells
    Joseph Parker
    Division of Cell Biology, Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, United Kingdom
    Curr Biol 16:2058-65. 2006
    ..The results argue that the gauging of P compartment size is due, at least in part, to cells surviving and growing according to Spi availability. These data offer mechanistic insight into how diffusible molecules control organ size...
  3. doi Staphylinids
    Joseph Parker
    Department of Genetics and Development, Columbia University, New York, NY 10032, USA, and Division of Invertebrate Zoology, American Museum of Natural History, New York, NY 10024, USA Electronic address
    Curr Biol 27:R49-R51. 2017
    ..Joe Parker introduces the staphylinids or 'rove beetles', the most species-rich groups of insect on Earth...
  4. ncbi Jubogaster towai, a new Neotropical genus and species of Trogastrini (Coleoptera: Staphylinidae: Pselaphinae) exhibiting myrmecophily and extreme body enlargement
    Joseph Parker
    Department of Genetics and Development, Columbia University, 701 West 168th Street, New York, NY 10032, USA
    Zootaxa 3630:369-78. 2013
    ..Many of the largest pselaphine taxa are guests of social insect colonies. We discuss whether an evolutionary correlation (or causal relationship) exists between body enlargement and an inquilinous lifestyle in Pselaphinae...
  5. doi Specialized myrmecophily at the ecological dawn of modern ants
    Joseph Parker
    Department of Genetics and Development, Columbia University, New York, NY 10032, USA Division of Invertebrate Zoology, American Museum of Natural History, New York, NY 10024, USA Electronic address
    Curr Biol 24:2428-34. 2014
    ....
  6. doi Morphogens, nutrients, and the basis of organ scaling
    Joseph Parker
    Department of Genetics and Development, Columbia University College of Physicians and Surgeons, 701 West 168th Street, New York, NY 10032, USA
    Evol Dev 13:304-14. 2011
    ..Here, the problem is illustrated using the Drosophila wing--a paradigm for organ growth and size control--and a potential solution suggested...
  7. pmc Maintenance of imaginal disc plasticity and regenerative potential in Drosophila by p53
    Brent S Wells
    Department of Genetics and Development, Columbia University Medical Center, New York, NY 10032, USA
    Dev Biol 361:263-76. 2012
    ..These findings place p53 in a role as master coordinator of DNA and tissue repair following IR...
  8. pmc Compensatory proliferation in Drosophila imaginal discs requires Dronc-dependent p53 activity
    Brent S Wells
    Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Curr Biol 16:1606-15. 2006
    ..Here we provide evidence that Drosophila p53 (dp53) has a previously unidentified role in coordinating the compensatory growth response to tissue damage...
  9. ncbi Drosophila myc regulates organ size by inducing cell competition
    Claire de la Cova
    Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, 701 West 168th Street, Room 704, New York, NY 10032, USA
    Cell 117:107-16. 2004
    ..Modulating dmyc levels to create cell competition and hid-dependent cell death may be a mechanism used during normal development to control organ size...
  10. pmc Activated STAT regulates growth and induces competitive interactions independently of Myc, Yorkie, Wingless and ribosome biogenesis
    Aloma B Rodrigues
    Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA
    Development 139:4051-61. 2012
    ..As hyper-activated STATs are causal to tumorigenesis and stem cell niche occupancy, our results have therapeutic implications for cancer and regenerative medicine...
  11. pmc Control of wing size and proportions by Drosophila myc
    D Christine Wu
    Department of Genetics and Development, Columbia University, New York, New York 10032, USA
    Genetics 184:199-211. 2010
    ..Overall, however, an appropriate level of dMyc expression in the wing disc is necessary for each region to achieve a proportionately correct size...
  12. pmc Supercompetitor status of Drosophila Myc cells requires p53 as a fitness sensor to reprogram metabolism and promote viability
    Claire de la Cova
    Department of Genetics and Development, College of Physicians and Surgeons, Columbia University Medical Center, 701 West 168th Street, New York, NY 10032, USA
    Cell Metab 19:470-83. 2014
    ..Our findings suggest that the initial confrontation between precancerous and WT cells could enhance cancer cell fitness and promote tumor progression...
  13. pmc Soluble factors mediate competitive and cooperative interactions between cells expressing different levels of Drosophila Myc
    Nanami Senoo-Matsuda
    Department of Genetics and Development, Columbia University College of Physicians and Surgeons, 701 West 168th Street, HHSC 704, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 104:18543-8. 2007
    ....
  14. pmc Myc in model organisms: a view from the flyroom
    Claire de la Cova
    Department of Genetics and Development, Columbia University Medical Center, New York, NY 10032, USA
    Semin Cancer Biol 16:303-12. 2006
    ..In this review, we describe recent research on the biology of Myc and its family members in Drosophila, paying particular attention to its role in the control of growth during development...
  15. pmc Mechanisms of growth and homeostasis in the Drosophila wing
    Ricardo M Neto-Silva
    Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Annu Rev Cell Dev Biol 25:197-220. 2009
    ..We focus on two topics currently under intense study: the influence of pattern regulators on organ and tissue growth and the role of local competitive interactions between cells in tissue homeostasis and final size...
  16. ncbi Regeneration and transdetermination: new tricks from old cells
    Laura A Johnston
    Department of Genetics and Development, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Cell 120:288-90. 2005
    ....
  17. ncbi Wingless promotes cell survival but constrains growth during Drosophila wing development
    Laura A Johnston
    Department of Genetics and Development, College of Physicians and Surgeons Columbia University 701 West 168th Street, New York, NY 10032, USA
    Nat Cell Biol 5:827-33. 2003
    ..We propose that the cell-survival- and growth-constraining activities of Wg function to sculpt and delimit final wing size as part of its overall patterning programme...
  18. pmc Temporal regulation of metamorphic processes in Drosophila by the let-7 and miR-125 heterochronic microRNAs
    Elizabeth E Caygill
    Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Curr Biol 18:943-50. 2008
    ..Little is known, however, about their requirement outside the nematode or whether they universally control the timing of developmental processes...
  19. pmc New frontiers in cell competition
    Simon de Beco
    Department of Genetics and Development, Columbia University Medical Center, New York, NY 10032, USA
    Dev Dyn 241:831-41. 2012
    ....
  20. pmc Competitive interactions between cells: death, growth, and geography
    Laura A Johnston
    Department of Genetics and Development, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    Science 324:1679-82. 2009
    ..Both types of competition are conserved physiological processes, with much to tell us about how cellular neighborhoods influence cell behavior, and have importance to stem cell biology, regeneration and transplantation, and cancer...
  21. ncbi Control of growth and organ size in Drosophila
    Laura A Johnston
    Columbia University, Department of Genetics and Development, 701 West 168th Street, New York, NY, USA
    Bioessays 24:54-64. 2002
    ..In addition, we speculate about possible connections between the extrinsic and intrinsic pathways controlling growth and pattern...
  22. pmc Socializing with MYC: cell competition in development and as a model for premalignant cancer
    Laura A Johnston
    Department of Genetics and Development, Columbia University Medical Center, New York, New York 10032
    Cold Spring Harb Perspect Med 4:a014274. 2014
    ..Given the high number of tumors with deregulated MYC, studies of cell competition promise to yield insight into how the local environment yields to and participates in the early stages of tumor formation. ..