Erik Falck-Pedersen

Summary

Affiliation: Cornell University
Country: USA

Publications

  1. pmc Adeno-associated virus type 2 preferentially integrates single genome copies with defined breakpoints
    Tyler Janovitz
    Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10065, USA
    Virol J 11:15. 2014
  2. pmc Sensing adenovirus infection: activation of interferon regulatory factor 3 in RAW 264.7 cells
    Saskia C Stein
    Weill Medical College of Cornell University, Department of Microbiology and Immunology, Molecular Biology Graduate Program, New York, New York, USA
    J Virol 86:4527-37. 2012
  3. pmc Highly divergent integration profile of adeno-associated virus serotype 5 revealed by high-throughput sequencing
    Tyler Janovitz
    Tri Institutional MD PhD Program, Weill Medical College of Cornell University, New York, New York, USA
    J Virol 88:2481-8. 2014
  4. pmc High-throughput sequencing reveals principles of adeno-associated virus serotype 2 integration
    Tyler Janovitz
    Tri Institutional MD PhD Program, Weill Medical College of Cornell University, New York, New York, USA
    J Virol 87:8559-68. 2013

Research Grants

  1. AAV p51EE Rep mediated integration into Chr19 AAVS1 site
    Erik Falck Pedersen; Fiscal Year: 2006
  2. Ad5 Fiber and Penton mts: Influence on immune activation
    Erik Falck Pedersen; Fiscal Year: 2009

Collaborators

  • Erik Falck Pedersen
  • Tyler Janovitz
  • Michel Sadelain
  • Thiago Oliveira
  • Saskia C Stein
  • M J Imperiale
  • Isaac A Klein
  • Piali Mukherjee
  • Michel C Nussenzweig

Detail Information

Publications4

  1. pmc Adeno-associated virus type 2 preferentially integrates single genome copies with defined breakpoints
    Tyler Janovitz
    Department of Microbiology and Immunology, Weill Medical College of Cornell University, New York, NY 10065, USA
    Virol J 11:15. 2014
    ..Additional insight regarding the integration of AAV-2 into human genomic DNA could be gleaned by low-throughput sequencing of complete viral-chromosomal junctions...
  2. pmc Sensing adenovirus infection: activation of interferon regulatory factor 3 in RAW 264.7 cells
    Saskia C Stein
    Weill Medical College of Cornell University, Department of Microbiology and Immunology, Molecular Biology Graduate Program, New York, New York, USA
    J Virol 86:4527-37. 2012
    ..Based on these data, multiple DNA sensors contribute to an antiviral DNA recognition response, leading to TBK1-dependent IRF3 phosphorylation in RAW 264.7 cells...
  3. pmc Highly divergent integration profile of adeno-associated virus serotype 5 revealed by high-throughput sequencing
    Tyler Janovitz
    Tri Institutional MD PhD Program, Weill Medical College of Cornell University, New York, New York, USA
    J Virol 88:2481-8. 2014
    ..Algorithmic scanning identified 126 AAV-5 hot spots, the largest of which encompassed 3.3% of all integration events. The unique aspects of AAV-5 integration may provide novel tools for biotechnology and gene therapy...
  4. pmc High-throughput sequencing reveals principles of adeno-associated virus serotype 2 integration
    Tyler Janovitz
    Tri Institutional MD PhD Program, Weill Medical College of Cornell University, New York, New York, USA
    J Virol 87:8559-68. 2013
    ..These studies provide a new understanding of AAV integration biology through the use of unbiased high-throughput data acquisition and bioinformatics. ..

Research Grants2

  1. AAV p51EE Rep mediated integration into Chr19 AAVS1 site
    Erik Falck Pedersen; Fiscal Year: 2006
    ..abstract_text> ..
  2. Ad5 Fiber and Penton mts: Influence on immune activation
    Erik Falck Pedersen; Fiscal Year: 2009
    ..The results of these studies will not only hold practical implications for gene transfer applications, but will shed new light on fundamental aspects of the earliest phases of viral recognition by the immune system. ..