- Ageing of the heart reversed by youthful systemic factors!Andrew S Brack
Center for Regenerative Medicine, Massachusetts General Hospital, Harvard Medical School, Harvard Stem Cell Institute, Boston, MA, USA
EMBO J 32:2189-90. 2013..One such factor is GDF11. Exposure of aged mice to youthful systemic factors or GDF11 decreases cardiac hypertrophy of the heart...
- Adult muscle stem cells avoid death and PaxesAndrew Brack
Center of Regenerative Medicine, Massachusetts General Hospital, MGH Charles River Plaza North, Room 4232, Boston, MA 02114 2790, USA
Cell Stem Cell 5:132-4. 2009..In a recent Nature publication, Lepper et al. (2009) use cell-specific lineage tracing and temporally controllable gene deletion approaches to study muscle stem cell function and reveal age-dependent requirements for Pax gene expression...
- BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regenerationAndrew S Brack
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305 5235, USA
Dev Biol 335:93-105. 2009..These results suggest a critical role of BCL9/9-2 in the Wnt-mediated regulation of adult, as opposed to embryonic, myogenic progenitors...