K Hamamura

Summary

Affiliation: Indiana University
Country: USA

Publications

  1. doi request reprint In vitro and in silico analysis of an inhibitory mechanism of osteoclastogenesis by salubrinal and guanabenz
    Kazunori Hamamura
    Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, Indianapolis, IN 46202, USA Electronic address
    Cell Signal 27:353-62. 2015
  2. pmc Predicting and validating the pathway of Wnt3a-driven suppression of osteoclastogenesis
    Kazunori Hamamura
    Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, Indianapolis, IN 46202, USA Electronic address
    Cell Signal 26:2358-69. 2014
  3. pmc Knee loading reduces MMP13 activity in the mouse cartilage
    Kazunori Hamamura
    Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, SL220C, 723 West Michigan Street, Indianapolis, IN 46202, USA
    BMC Musculoskelet Disord 14:312. 2013
  4. doi request reprint Suppression of osteoclastogenesis through phosphorylation of eukaryotic translation initiation factor 2 alpha
    Kazunori Hamamura
    Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, SL155, 723 West Michigan Street, Indianapolis, IN, 46202, USA
    J Bone Miner Metab 31:618-28. 2013
  5. pmc Effects of salubrinal on development of osteoclasts and osteoblasts from bone marrow-derived cells
    Hiroki Yokota
    Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, 723 West Michigan Street, SL220, Indianapolis, IN 46202, USA
    BMC Musculoskelet Disord 14:197. 2013
  6. doi request reprint Salubrinal reduces expression and activity of MMP13 in chondrocytes
    K Hamamura
    Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, Indianapolis, IN 46202, USA
    Osteoarthritis Cartilage 21:764-72. 2013
  7. pmc Rac1 mediates load-driven attenuation of mRNA expression of nerve growth factor beta in cartilage and chondrocytes
    J W Shim
    Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, 723 West Michigan Street, Indianapolis, IN 46202, USA
    J Musculoskelet Neuronal Interact 13:372-9. 2013

Detail Information

Publications8

  1. doi request reprint In vitro and in silico analysis of an inhibitory mechanism of osteoclastogenesis by salubrinal and guanabenz
    Kazunori Hamamura
    Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, Indianapolis, IN 46202, USA Electronic address
    Cell Signal 27:353-62. 2015
    ..Collectively, a systems-biology approach allows the prediction of a RANKL-salubrinal/guanabenz-NFATc1 regulatory axis, and in vitro assays validate an involvement of AP-1 transcription factors in suppression of osteoclastogenesis. ..
  2. pmc Predicting and validating the pathway of Wnt3a-driven suppression of osteoclastogenesis
    Kazunori Hamamura
    Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, Indianapolis, IN 46202, USA Electronic address
    Cell Signal 26:2358-69. 2014
    ....
  3. pmc Knee loading reduces MMP13 activity in the mouse cartilage
    Kazunori Hamamura
    Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, SL220C, 723 West Michigan Street, Indianapolis, IN 46202, USA
    BMC Musculoskelet Disord 14:312. 2013
    ..In this study, we examined the effects of knee loading on the activity of matrix metalloproteinase13 (MMP13) and evaluated the role of p38 MAPK and Rac1 GTPase in the regulation of MMP13...
  4. doi request reprint Suppression of osteoclastogenesis through phosphorylation of eukaryotic translation initiation factor 2 alpha
    Kazunori Hamamura
    Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, SL155, 723 West Michigan Street, Indianapolis, IN, 46202, USA
    J Bone Miner Metab 31:618-28. 2013
    ..The results suggest that eIF2α-mediated signaling might provide a novel therapeutic target for preventing bone loss in osteoporosis. ..
  5. pmc Effects of salubrinal on development of osteoclasts and osteoblasts from bone marrow-derived cells
    Hiroki Yokota
    Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, 723 West Michigan Street, SL220, Indianapolis, IN 46202, USA
    BMC Musculoskelet Disord 14:197. 2013
    ..We addressed a question: are salubrinal's actions more potent to the cells isolated from the osteoporotic mice than those isolated from the control mice?..
  6. doi request reprint Salubrinal reduces expression and activity of MMP13 in chondrocytes
    K Hamamura
    Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, Indianapolis, IN 46202, USA
    Osteoarthritis Cartilage 21:764-72. 2013
    ....
  7. pmc Rac1 mediates load-driven attenuation of mRNA expression of nerve growth factor beta in cartilage and chondrocytes
    J W Shim
    Department of Biomedical Engineering, Indiana University Purdue University Indianapolis, 723 West Michigan Street, Indianapolis, IN 46202, USA
    J Musculoskelet Neuronal Interact 13:372-9. 2013
    ..To determine effect of gentle loads applied to the knee on mRNA expression of nerve growth factor, particularly, the active beta subunit (NGFβ) in cartilage and chondrocyte...