Carolyn B Howard

Summary

Affiliation: Jackson State University
Country: USA

Publications

  1. pmc Chemotherapeutic Vulnerability of Triple-negative Breast Cancer Cell-derived Tumors to Pretreatment with Vernonia amygdalina Aqueous Extracts
    Carolyn B Howard
    Department of Biology, College of Science Engineering and Technology, Jackson State University, Jackson, MS, U S A
    Anticancer Res 36:3933-43. 2016
  2. ncbi request reprint Time and dose-dependent modulation of phase 1 and phase 2 gene expression in response to treatment of MCF-7 cells with a natural anti-cancer agent
    C B Howard
    Breast Cancer Research Laboratory, Department of Biology, Center for Environmental Health, Jackson State University, 1400 J R Lynch Street, Jackson, Mississippi 39217, USA
    Cell Mol Biol (Noisy-le-grand) 49:1057-65. 2003
  3. pmc Effects of pristane on cytochrome P450 isozyme expression in rat tissues
    Carolyn B Howard
    Breast Cancer Research Laboratory, Department of Biology, and NIH Center for Environmental Health, College of Science, Engineering and Technology, Jackson State University, Jackson, Mississippi, USA
    Int J Environ Res Public Health 2:138-46. 2005
  4. pmc Analysis of gene regulation in rabbit corneal epithelial cells induced by ultraviolet radiation
    Jacqueline J Stevens
    Molecular Biology Research Laboratory, NIH Center for Environmental Health, College of Science, Engineering and Technology, Jackson State University, 1400 J R Lynch Street, Jackson, Mississippi 39217, USA
    Int J Environ Res Public Health 2:51-7. 2005
  5. ncbi request reprint Ethanol modulates the growth of human breast cancer cells in vitro
    Ernest B Izevbigie
    The Molecular Genetics and Molecular and Cellular Signaling Laboratory, Department of Biology, and Center for Environmental Health, Jackson State University, Jackson, Mississippi 39217, USA
    Exp Biol Med (Maywood) 227:260-5. 2002
  6. pmc Basic apoptotic mechanisms of lead toxicity in human leukemia (HL-60) cells
    Clement G Yedjou
    Cellomics and Toxicogenomics Research Laboratory, NIH Center for Environmental Health, College of Science, Engineering and Technology, Jackson State University, Jackson, MS 39217, USA
    Int J Environ Res Public Health 7:2008-17. 2010

Research Grants

Detail Information

Publications6

  1. pmc Chemotherapeutic Vulnerability of Triple-negative Breast Cancer Cell-derived Tumors to Pretreatment with Vernonia amygdalina Aqueous Extracts
    Carolyn B Howard
    Department of Biology, College of Science Engineering and Technology, Jackson State University, Jackson, MS, U S A
    Anticancer Res 36:3933-43. 2016
    ..VA extracts arrest cell proliferation and induce apoptosis in vitro and inhibit growth of implanted tumors and show chemo-preventive efficacy in vivo...
  2. ncbi request reprint Time and dose-dependent modulation of phase 1 and phase 2 gene expression in response to treatment of MCF-7 cells with a natural anti-cancer agent
    C B Howard
    Breast Cancer Research Laboratory, Department of Biology, Center for Environmental Health, Jackson State University, 1400 J R Lynch Street, Jackson, Mississippi 39217, USA
    Cell Mol Biol (Noisy-le-grand) 49:1057-65. 2003
    ..A. extract as a potential clinically useful natural anti-cancer agent and provide some support for the concept that modulation in CYP3A4 expression in response to treatment is relevant to prognosis...
  3. pmc Effects of pristane on cytochrome P450 isozyme expression in rat tissues
    Carolyn B Howard
    Breast Cancer Research Laboratory, Department of Biology, and NIH Center for Environmental Health, College of Science, Engineering and Technology, Jackson State University, Jackson, Mississippi, USA
    Int J Environ Res Public Health 2:138-46. 2005
    ..This pristane-mediated effect clearly could be a contributing factor in the chemical carcinogenesis of the previously observed lymphoid malignancies, and a possible basis for the tumor enhancing effects of pristane...
  4. pmc Analysis of gene regulation in rabbit corneal epithelial cells induced by ultraviolet radiation
    Jacqueline J Stevens
    Molecular Biology Research Laboratory, NIH Center for Environmental Health, College of Science, Engineering and Technology, Jackson State University, 1400 J R Lynch Street, Jackson, Mississippi 39217, USA
    Int J Environ Res Public Health 2:51-7. 2005
    ..Future experiments will involve sequence analysis of cloned inserts. The identification of these genes through sequence analysis could lead to a better understanding of cataract formation via DNA damage and mechanisms of prevention...
  5. ncbi request reprint Ethanol modulates the growth of human breast cancer cells in vitro
    Ernest B Izevbigie
    The Molecular Genetics and Molecular and Cellular Signaling Laboratory, Department of Biology, and Center for Environmental Health, Jackson State University, Jackson, Mississippi 39217, USA
    Exp Biol Med (Maywood) 227:260-5. 2002
    ..02), and subsequent cell growth by 200% (P < 0.05) in a MEK1 inhibitor (PD098059)-sensitive fashion, thus suggesting that the Ras/MEK/MAPK signaling pathways are crucial for ethanol-induced MCF-7 cell growth...
  6. pmc Basic apoptotic mechanisms of lead toxicity in human leukemia (HL-60) cells
    Clement G Yedjou
    Cellomics and Toxicogenomics Research Laboratory, NIH Center for Environmental Health, College of Science, Engineering and Technology, Jackson State University, Jackson, MS 39217, USA
    Int J Environ Res Public Health 7:2008-17. 2010
    ....

Research Grants1

  1. Enhance and Expand University Research Infrastructure
    Carolyn Howard; Fiscal Year: 2008
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