Theresa Jacob

Summary

Affiliation: Maimonides Medical Center
Location: NY, USA
Publications:
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Publications

  1. ncbi A nanotechnology-based delivery system: Nanobots. Novel vehicles for molecular medicine
    T Jacob
    Clinical Trials Unit and Translational Research, Maimonides Medical Center, Brooklyn, New York, NY, USA
    J Cardiovasc Surg (Torino) 52:159-67. 2011
  2. ncbi Comparison of computed tomography angiography to contrast arteriography for patients undergoing evaluation for lower extremity revascularization
    Anil Hingorani
    Division of Vascular Surgery, Department of Surgery, Mainmonides Medcine Center, Brooklyn, New York 11219, USA
    Vasc Endovascular Surg 41:115-9. 2007
  3. ncbi A comparison of magnetic resonance angiography, contrast arteriography, and duplex arteriography for patients undergoing lower extremity revascularization
    Anil Hingorani
    Department of Surgery, Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    Ann Vasc Surg 18:294-301. 2004
  4. ncbi A 10-year experience with complementary distal arteriovenous fistula and deep vein interposition for infrapopliteal prosthetic bypasses
    Anil P Hingorani
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    Vasc Endovascular Surg 39:401-9. 2005
  5. ncbi Limitations of and lessons learned from clinical experience of 1,020 duplex arteriography
    Anil P Hingorani
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY, USA
    Vascular 16:147-53. 2008
  6. ncbi Impact of duplex arteriography in the evaluation of acute lower limb ischemia from thrombosed popliteal aneurysms
    Sreedhar Kallakuri
    Maimonides Medical Center, Brooklyn, NY 11219, USA
    Vasc Endovascular Surg 40:23-5. 2006
  7. ncbi Mini skin incision for carotid endarterectomy (CEA): a new and safe alternative to the standard approach
    Enrico Ascher
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY, USA
    J Vasc Surg 42:1089-93. 2005
  8. doi Predictive factors of success following radio-frequency stylet (RFS) ablation of incompetent perforating veins (IPV)
    Anil P Hingorani
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    J Vasc Surg 50:844-8. 2009
  9. doi Iatrogenic injuries of the common femoral artery (CFA) and external iliac artery (EIA) during endograft placement: an underdiagnosed entity
    Anil P Hingorani
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    J Vasc Surg 50:505-9; discussion 509. 2009
  10. ncbi Early transposition of the sartorius muscle for exposed patent infrainguinal bypass grafts
    Richard Schutzer
    Division of Vascular Surgery, Department of Surgery, Maimonides Medical Center, 4802 Tenth Avenue, Brooklyn, NY 11219, USA
    Vasc Endovascular Surg 39:159-62. 2005

Collaborators

  • Enrico Ascher
  • Anil Hingorani
  • P Gupta
  • N Marks
  • Sreedhar Kallakuri
  • Richard Schutzer
  • Fred Usoh
  • Alexander Shiferson
  • Nirav Patel
  • Victor Tran
  • Natalia Markevich
  • Alexander Hou
  • William Yorkovich
  • Kapil Gopal
  • Alessandra Puggioni
  • Suresh Nahata
  • Prasad Gade
  • Natalia Markewich
  • Khodadad Mehraein
  • Marcel Scheinman
  • Murali Pagala

Detail Information

Publications38

  1. ncbi A nanotechnology-based delivery system: Nanobots. Novel vehicles for molecular medicine
    T Jacob
    Clinical Trials Unit and Translational Research, Maimonides Medical Center, Brooklyn, New York, NY, USA
    J Cardiovasc Surg (Torino) 52:159-67. 2011
    ..Our objective was to design and clone a virus-free p53 construct, targeted to express specifically in vascular smooth muscle cells (SMCs), via a nanoparticle-based delivery system for therapeutic modulation in vascular wall...
  2. ncbi Comparison of computed tomography angiography to contrast arteriography for patients undergoing evaluation for lower extremity revascularization
    Anil Hingorani
    Division of Vascular Surgery, Department of Surgery, Mainmonides Medcine Center, Brooklyn, New York 11219, USA
    Vasc Endovascular Surg 41:115-9. 2007
    ..A review of the data obtained in this series indicated that computed tomography angiography appears to be unable to obtain adequate information in this highly selected population at our institution...
  3. ncbi A comparison of magnetic resonance angiography, contrast arteriography, and duplex arteriography for patients undergoing lower extremity revascularization
    Anil Hingorani
    Department of Surgery, Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    Ann Vasc Surg 18:294-301. 2004
    ..When severe tibial calcification or very low flow states are identified, CA may be necessary for patients undergoing DA...
  4. ncbi A 10-year experience with complementary distal arteriovenous fistula and deep vein interposition for infrapopliteal prosthetic bypasses
    Anil P Hingorani
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    Vasc Endovascular Surg 39:401-9. 2005
    ..This technique appears to offer reasonable patency and limb salvage rates in patients in whom autogenous bypass grafts are not feasible...
  5. ncbi Limitations of and lessons learned from clinical experience of 1,020 duplex arteriography
    Anil P Hingorani
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY, USA
    Vascular 16:147-53. 2008
    ..In an effort to further explore the strengths and weaknesses of DA, we reviewed our evolving experience with DA from January 1, 1998, to January 1, 2005...
  6. ncbi Impact of duplex arteriography in the evaluation of acute lower limb ischemia from thrombosed popliteal aneurysms
    Sreedhar Kallakuri
    Maimonides Medical Center, Brooklyn, NY 11219, USA
    Vasc Endovascular Surg 40:23-5. 2006
    ..Contrary to previously published reports, urgent revascularization of an acutely ischemic extremity from thrombosed popliteal aneurysm can provide excellent rates of limb salvage...
  7. ncbi Mini skin incision for carotid endarterectomy (CEA): a new and safe alternative to the standard approach
    Enrico Ascher
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY, USA
    J Vasc Surg 42:1089-93. 2005
    ....
  8. doi Predictive factors of success following radio-frequency stylet (RFS) ablation of incompetent perforating veins (IPV)
    Anil P Hingorani
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    J Vasc Surg 50:844-8. 2009
    ..To evaluate potential predictive factors associated with success or failure of incompetent perforating veins (IPVs) treated with radio-frequency stylet (RFS)...
  9. doi Iatrogenic injuries of the common femoral artery (CFA) and external iliac artery (EIA) during endograft placement: an underdiagnosed entity
    Anil P Hingorani
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    J Vasc Surg 50:505-9; discussion 509. 2009
    ....
  10. ncbi Early transposition of the sartorius muscle for exposed patent infrainguinal bypass grafts
    Richard Schutzer
    Division of Vascular Surgery, Department of Surgery, Maimonides Medical Center, 4802 Tenth Avenue, Brooklyn, NY 11219, USA
    Vasc Endovascular Surg 39:159-62. 2005
    ..Furthermore, the chance of infection of the native artery or bypass may be reduced. Familiarity with this simple technique can be a valuable tool for the vascular surgeon...
  11. ncbi Duplex arteriography prior to femoral-popliteal reconstruction in claudicants: a proposal for a new shortened protocol
    Enrico Ascher
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    Ann Vasc Surg 18:544-51. 2004
    ..However, the short protocol does not avert the need for completion arteriography of the inflow arteries and readiness to perform endovascular procedures to correct lesions not suspected by common femoral artery waveform analysis...
  12. ncbi Deep venous thrombosis after radiofrequency ablation of greater saphenous vein: a word of caution
    Anil P Hingorani
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    J Vasc Surg 40:500-4. 2004
    ..However, our initial enthusiasm for this minimally invasive technique has been tempered by our preliminary experience with its potentially lethal complication, deep venous thrombosis (DVT)...
  13. ncbi Role of duplex arteriography as the sole preoperative imaging modality prior to lower extremity revascularization surgery in diabetic and renal patients
    Enrico Ascher
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    Ann Vasc Surg 18:433-9. 2004
    ..The use of DA presents a safe and reliable option to prebypass CA for many patients with diabetes or CRI. The ease of use and favorable patient outcomes achieved by this imaging modality may rival the use of CA for these patients...
  14. ncbi Hybrid approach for treatment of behind the knee popliteal artery aneurysms
    Anil P Hingorani
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    Vascular 17:290-2. 2009
    ..The proposed technique is simple, effective and averts extensive dissections required to minimize blood loss...
  15. doi 219 vascular fellows' perception of the future of vascular surgery
    Anil P Hingorani
    Division of Vascular Surgery, Maimonides Medical Center, 4802 10th Avenue, Brooklyn, NY 11219, USA
    Ann Vasc Surg 23:453-7. 2009
    ..This survey suggests that several significant issues exist in the minds of vascular trainees that have not been addressed and may present opportunities for further dialogue...
  16. doi Self-assessment of the training of vascular fellows: survey results of 219 vascular fellows from 2004 through 2007
    Anil P Hingorani
    Division of Vascular Services, Maimonides Medical Center, Brooklyn, NY 11219, USA
    Vasc Endovascular Surg 43:185-9. 2009
    ..Conclusions. The results of this Survey suggest that several significant issues are reflected in the minds of vascular trainees...
  17. ncbi Cerebral hyperperfusion syndrome after carotid endarterectomy: predictive factors and hemodynamic changes
    Enrico Ascher
    Division of Vascular Surgery, Department of Surgery, Maimonides Medical Center, Brooklyn, NY, USA
    J Vasc Surg 37:769-77. 2003
    ..We describe our experience with CHS, which diverges from published reports...
  18. ncbi Small popliteal artery aneurysms: are they clinically significant?
    Enrico Ascher
    Division of Vascular Surgery, Department of Surgery, Maimonides Medical Center, Brooklyn, NY, USA
    J Vasc Surg 37:755-60. 2003
    ..We undertook this study to determine whether popliteal artery aneurysm diameter correlates with initial symptoms and presence of associated occlusive disease...
  19. ncbi Predictive factors of femoropopliteal patency after suboptimal duplex-guided balloon angioplasty and stenting: is recoil a bad sign?
    Enrico Ascher
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    Vascular 16:263-8. 2008
    ..To our knowledge, this is the first report ever to document plaque recoil as a predictor of balloon angioplasty site failure notwithstanding stent placement...
  20. doi Prospective randomized study comparing the clinical outcomes between inferior vena cava Greenfield and TrapEase filters
    Fred Usoh
    Division of Vascular Services, Maimonides Medical Center, Brooklyn, NY 11219, USA
    J Vasc Surg 52:394-9. 2010
    ....
  21. ncbi Endovascular management of axillofemoral bypass graft stump syndrome
    Sreedhar Kallakuri
    Division of Vascular Surgery, Department of Surgery, Maimonides Medical Center, 4802 Tenth Avenue, Brooklyn, NY 11219, USA
    J Vasc Surg 38:833-5. 2003
    ..We report two patients with critical upper extremity ischemia secondary to stump syndrome and its successful management with endovascular techniques...
  22. ncbi Prospective evaluation of combined upper and lower extremity DVT
    Anil P Hingorani
    Maimonides Medical Center, Brooklyn, NY, USA
    Vasc Endovascular Surg 40:131-4. 2006
    ..These data serve to confirm previous studies, on a larger scale, that there should be a high index of suspicion in patients with UEDVT of a coexistent LEDVT...
  23. ncbi Morbidity and mortality associated with brachial vein thrombosis
    Anil Hingorani
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY, USA
    Ann Vasc Surg 20:297-300. 2006
    ..Based on these data, we suggest that UEDVT may be thought of as a marker for the severity of systemic illness of the patient rather than just as a cause of venous thromboembolism...
  24. ncbi Regional anesthesia: preferred technique for venodilatation in the creation of upper extremity arteriovenous fistulae
    Anil P Hingorani
    Maimonides Medical Center, Division of Vascular Surgery, Brooklyn, NY, USA
    Vascular 14:23-6. 2006
    ..The venodilatation observed is augmented compared with that using a tourniquet and may allow more options for access placements...
  25. ncbi Role of apoptosis and proteolysis in the pathogenesis of iliac artery aneurysms
    Theresa Jacob
    Division of Vascular Surgery, Department of Surgery, Maimonides Medical Center, Brooklyn, NY, USA
    Vascular 13:34-42. 2005
    ..In addition to compromising the mechanical integrity of the vessel wall, VSMC loss may contribute to imbalance in the protein profile, accelerating extracellular matrix degradation that could favor IAA development...
  26. ncbi The effect of von hippel-lindau gene transfer on human vascular smooth muscle cell proliferation and apoptosis
    Theresa Jacob
    Division of Vascular Surgery, Department of Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    Vasc Endovascular Surg 39:25-32. 2005
    ..Overexpression of VHL suppresses HASMC proliferation and regulates apoptosis. Further experiments are indicated to examine whether VHL may be a useful adjunct in limiting myointimal hyperplasia...
  27. doi Long-term follow-up for superior vena cava filter placement
    Fred Usoh
    Division of Vascular Surgery, Department of Surgery, Maimonides Medical Center, Brooklyn, New York 11219, USA
    Ann Vasc Surg 23:350-4. 2009
    ..These data help to reaffirm the safety and effectiveness of SVC filter placement. However, SVC perforation in young males remains a significant issue...
  28. ncbi Differential expression of YAMA/CPP-32 by T lymphocytes in popliteal artery aneurysm
    Theresa Jacob
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, New York 11219, USA
    J Surg Res 112:111-6. 2003
    ..This investigation examines the expression of a cell death-promoting molecule, a cysteine protease, YAMA/CPP-32 in a series of PAA specimens...
  29. doi Patterns of Restraint Utilization in a Community Hospital's Psychiatric Inpatient Units
    Theresa Jacob
    Department of Psychiatry, Maimonides Medical Center, 4802 Tenth Avenue, Brooklyn, NY, 11219, USA
    Psychiatr Q 87:31-48. 2016
    ....
  30. doi p53 gene therapy modulates signal transduction in the apoptotic and cell cycle pathways downregulating neointimal hyperplasia
    Theresa Jacob
    Department of Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    Vasc Endovascular Surg 46:45-53. 2012
    ..To investigate the molecular mechanisms that lead to inhibition of intimal hyperplasia (IH) following p53 gene therapy...
  31. ncbi The effect of cotinine on telomerase activity in human vascular smooth muscle cells
    T Jacob
    Department of Surgery, Division of Vascular Surgery, Maimonides Medical Center, Brooklyn New York, New York, NY, USA
    J Cardiovasc Surg (Torino) 50:345-9. 2009
    ..The purpose of our experiment was to evaluate the effect of cotinine on proliferative potential of vascular smooth muscle cells via its effects on telomerase activity...
  32. doi Evidence for telomerase activation in VSMCs exposed to hyperglycemic and hyperhomocysteinemic conditions
    Theresa Jacob
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, New York 11219, USA
    Angiology 60:562-8. 2009
    ..We examined the proliferative response of VSMCs, resulting from hyperglycemia and hyperhomocysteinemia and their effects on telomerase activity...
  33. ncbi Risk factors for mortality in patients with upper extremity and internal jugular deep venous thrombosis
    Anil Hingorani
    Division of Vascular Surgery, Department of Surgery, Maimonides Medical Center, 4802 Tenth Avenue, Brooklyn, NY 11219, USA
    J Vasc Surg 41:476-8. 2005
    ..To elucidate the natural history of upper extremity deep venous thrombosis (UEDVT), we examined factors that may contribute to the high mortality associated with UEDVT...
  34. ncbi Bilateral internal iliac artery aneurysm infected with Campylobacter fetus
    Alexander Shiferson
    Division of Vascular Surgery, Department of Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    Vascular 17:226-9. 2009
    ..He was promptly taken to the operating room for ligation of the right internal iliac artery aneurysm. The patient's postoperative course was unremarkable. He was discharged on ciprofloxacin for 14 days...
  35. ncbi Protective effect of glycine in mesenteric ischemia and reperfusion injury in a rat model
    Sreedhar Kallakuri
    Department of Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    J Vasc Surg 38:1113-20. 2003
    ..Glycine has a protective effect in renal and skeletal muscle ischemia. The purpose of this study was to evaluate the effect of glycine in mesenteric ischemia and reperfusion injury in a rat model...
  36. ncbi Preliminary results of the new 6F TrapEase inferior vena cava filter
    Richard Schutzer
    Division of Vascular Surgery, Department of Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    Ann Vasc Surg 17:103-6. 2003
    ..While this investigation does demonstrate a low overall complication rate of this new device, it raises the concern of an increase in IVC thrombosis rate...
  37. ncbi Activation of p38MAPK signaling cascade in a VSMC injury model: role of p38MAPK inhibitors in limiting VSMC proliferation
    T Jacob
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY 11219, USA
    Eur J Vasc Endovasc Surg 29:470-8. 2005
    ..We examine p38MAPK activation in response to vascular cell injury, its biological effects and determine whether selective p38MAPK inhibitors, SB220025/SB203580, decrease vascular smooth muscle cell (VSMC) proliferation...
  38. ncbi Expression of molecular mediators of apoptosis and their role in the pathogenesis of lower-extremity varicose veins
    E Ascher
    Division of Vascular Surgery, Maimonides Medical Center, Brooklyn, NY, USA
    J Vasc Surg 33:1080-6. 2001
    ..Both bax and PARP are downregulated in varicose veins, as compared with healthy veins, and this may play a significant role in the pathogenesis of varicose veins...