Affiliation: Mayo Clinic
- Heit J, Armasu S, Asmann Y, Cunningham J, Matsumoto M, Petterson T, et al. A genome-wide association study of venous thromboembolism identifies risk variants in chromosomes 1q24.2 and 9q. J Thromb Haemost. 2012;10:1521-31 pubmed publisher..0 and 1.51 for minor allele frequencies=0.05 and 0.5, respectively (α=1×10(-8); 1% VTE prevalence). Apart from F5 rs6025, ABO rs8176719, rs2519093 and F2 rs1799963, additional common and high VTE-risk SNPs among whites are unlikely. ..
- de Andrade M, Armasu S, McCauley B, Petterson T, Heit J. Identification of Genetic Interaction with Risk Factors Using a Time-To-Event Model. Int J Environ Res Public Health. 2017;14: pubmed publisher..We showed that the time-to-event model is a useful approach for identifying potential hazard-modification of the genetic variants when the event of interest (VTE) occurs due to a risk factor (pre- or post-partum). ..