SCOTT BARMAN

Summary

Affiliation: Medical College of Georgia
Country: USA

Publications

  1. ncbi request reprint cAMP activates BKCa channels in pulmonary arterial smooth muscle via cGMP-dependent protein kinase
    Scott A Barman
    Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, Georgia 30912, USA
    Am J Physiol Lung Cell Mol Physiol 284:L1004-11. 2003
  2. ncbi request reprint Effect of protein kinase C inhibition on hypoxic pulmonary vasoconstriction
    S A Barman
    Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, Georgia 30912, USA
    Am J Physiol Lung Cell Mol Physiol 280:L888-95. 2001
  3. ncbi request reprint Mechanism of endothelin-1 activation of MAP kinases in neonatal pulmonary vascular smooth muscle
    Scott A Barman
    Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, GA 30912, USA
    Lung 183:425-39. 2005
  4. ncbi request reprint Hypoxia modulates cyclic AMP activation of BkCa channels in rat pulmonary arterial smooth muscle
    Scott A Barman
    Department of Pharmacology and Toxicology, School of Medicine, Medical College of Georgia, Augusta 30912, USA
    Lung 183:353-61. 2005
  5. ncbi request reprint Effect of nitric oxide on mitogen-activated protein kinases in neonatal pulmonary vascular smooth muscle
    Scott A Barman
    Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta 30912, USA
    Lung 183:325-35. 2005
  6. ncbi request reprint Protein kinase C inhibits cyclic adenosine monophosphate-induced calcium-activated and voltage-activated potassium channel activity in fawn-hooded rat pulmonary arterial smooth muscle via phosphodiesterases
    Scott A Barman
    Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, GA 30912, USA
    Chest 128:576S. 2005
  7. ncbi request reprint PKC activates BKCa channels in rat pulmonary arterial smooth muscle via cGMP-dependent protein kinase
    Scott A Barman
    Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, GA 30912, USA
    Am J Physiol Lung Cell Mol Physiol 286:L1275-81. 2004
  8. ncbi request reprint Protein kinase C inhibits BKCa channel activity in pulmonary arterial smooth muscle
    Scott A Barman
    Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, Georgia 30912, USA
    Am J Physiol Lung Cell Mol Physiol 286:L149-55. 2004
  9. pmc Estrogen-induced contraction of coronary arteries is mediated by superoxide generated in vascular smooth muscle
    Richard E White
    Department of Pharmacology and Toxicology, Medical College of Georgia, 1120 15th St, Augusta, GA 30912 2300, USA
    Am J Physiol Heart Circ Physiol 289:H1468-75. 2005
  10. ncbi request reprint Effect of PKC isozyme inhibition on forskolin-induced activation of BKCa channels in rat pulmonary arterial smooth muscle
    Shu Zhu
    Department of Pharmacology and Toxicology, Medical College of Georgia, 1170 15th street, Augusta, Georgia 30912, USA
    Lung 184:89-97. 2006

Research Grants

Detail Information

Publications12

  1. ncbi request reprint cAMP activates BKCa channels in pulmonary arterial smooth muscle via cGMP-dependent protein kinase
    Scott A Barman
    Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, Georgia 30912, USA
    Am J Physiol Lung Cell Mol Physiol 284:L1004-11. 2003
    ....
  2. ncbi request reprint Effect of protein kinase C inhibition on hypoxic pulmonary vasoconstriction
    S A Barman
    Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, Georgia 30912, USA
    Am J Physiol Lung Cell Mol Physiol 280:L888-95. 2001
    ..In addition, L-type voltage-dependent Ca(2+) channel blockade may prevent the onset of the hypoxia- and PKC-induced vasoconstrictor response in the canine pulmonary vasculature...
  3. ncbi request reprint Mechanism of endothelin-1 activation of MAP kinases in neonatal pulmonary vascular smooth muscle
    Scott A Barman
    Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, GA 30912, USA
    Lung 183:425-39. 2005
    ....
  4. ncbi request reprint Hypoxia modulates cyclic AMP activation of BkCa channels in rat pulmonary arterial smooth muscle
    Scott A Barman
    Department of Pharmacology and Toxicology, School of Medicine, Medical College of Georgia, Augusta 30912, USA
    Lung 183:353-61. 2005
    ..These results suggest that this phenomenon may serve as a physiological mechanism to cause hypoxic vasoconstriction in the pulmonary circulation via modulation of BKCa channels...
  5. ncbi request reprint Effect of nitric oxide on mitogen-activated protein kinases in neonatal pulmonary vascular smooth muscle
    Scott A Barman
    Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta 30912, USA
    Lung 183:325-35. 2005
    ..Collectively, these data demonstrate the expression and phosphorylation of specific MAPKs in rat neonatal pulmonary vascular smooth muscle and suggests that the NO signaling pathway modulates MAPK activation by ET-1...
  6. ncbi request reprint Protein kinase C inhibits cyclic adenosine monophosphate-induced calcium-activated and voltage-activated potassium channel activity in fawn-hooded rat pulmonary arterial smooth muscle via phosphodiesterases
    Scott A Barman
    Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, GA 30912, USA
    Chest 128:576S. 2005
  7. ncbi request reprint PKC activates BKCa channels in rat pulmonary arterial smooth muscle via cGMP-dependent protein kinase
    Scott A Barman
    Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, GA 30912, USA
    Am J Physiol Lung Cell Mol Physiol 286:L1275-81. 2004
    ....
  8. ncbi request reprint Protein kinase C inhibits BKCa channel activity in pulmonary arterial smooth muscle
    Scott A Barman
    Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, Georgia 30912, USA
    Am J Physiol Lung Cell Mol Physiol 286:L149-55. 2004
    ....
  9. pmc Estrogen-induced contraction of coronary arteries is mediated by superoxide generated in vascular smooth muscle
    Richard E White
    Department of Pharmacology and Toxicology, Medical College of Georgia, 1120 15th St, Augusta, GA 30912 2300, USA
    Am J Physiol Heart Circ Physiol 289:H1468-75. 2005
    ....
  10. ncbi request reprint Effect of PKC isozyme inhibition on forskolin-induced activation of BKCa channels in rat pulmonary arterial smooth muscle
    Shu Zhu
    Department of Pharmacology and Toxicology, Medical College of Georgia, 1170 15th street, Augusta, Georgia 30912, USA
    Lung 184:89-97. 2006
    ....
  11. ncbi request reprint Vasoconstrictor effect of endothelin-1 on hypertensive pulmonary arterial smooth muscle involves Rho-kinase and protein kinase C
    Scott A Barman
    Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, GA 30912, USA
    Am J Physiol Lung Cell Mol Physiol 293:L472-9. 2007
    ..These results suggest that both PKC and Rho/Rho-kinase mediate the heightened pulmonary vascular response to ET-1 in hypertensive pulmonary arterial smooth muscle...
  12. ncbi request reprint Nongenomic, endothelium-independent effects of estrogen on human coronary smooth muscle are mediated by type I (neuronal) NOS and PI3-kinase-Akt signaling
    Guichun Han
    Department of Pharmacology and Toxicology, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912 2300, USA
    Am J Physiol Heart Circ Physiol 293:H314-21. 2007
    ..These findings now provide a molecular mechanism that can explain the clinical observation that estrogen enhances coronary blood flow in patients with diseased or damaged coronary arteries...

Research Grants1

  1. PKC Signaling in cAMP-Induced Pulmonary Vasodilation
    SCOTT BARMAN; Fiscal Year: 2010
    ..Progress of these studies will provide important knowledge towards the development of novel therapeutic agents that will help reduce the morbidity and mortality associated with pulmonary hypertension. ..