J K Stiles

Summary

Affiliation: Morehouse School of Medicine
Country: USA

Publications

  1. ncbi request reprint Trichomonas vaginalis: characterization of a family of P-type ATPase genes
    Preetam H Shah
    Department of Microbiology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216 4505, USA
    Parasitol Int 51:41-51. 2002
  2. ncbi request reprint Apoptosis of rat granulosa cells after staurosporine and serum withdrawal is suppressed by adenovirus-directed overexpression of prohibitin
    Indrajit Chowdhury
    Department of Obstetrics and Gynecology, Morehouse School of Medicine, Atlanta, Georgia 30310, USA
    Endocrinology 148:206-17. 2007
  3. ncbi request reprint Trypanosome apoptotic factor mediates apoptosis in human brain vascular endothelial cells
    Jonathan K Stiles
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, 720 Westview Dr S W, Atlanta, GA 30310 1495, USA
    Mol Biochem Parasitol 133:229-40. 2004
  4. ncbi request reprint Trypanosoma brucei infection induces apoptosis and up-regulates neuroleukin expression in the cerebellum
    J K Stiles
    Department of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, 720 Westview Dr S W, Atlanta, GA 30310 1495, USA
    Ann Trop Med Parasitol 95:797-810. 2001
  5. ncbi request reprint Identification of surface-membrane P-type ATPases resembling fungal K(+)- and Na(+)-ATPases, in Trypanosoma brucei, Trypanosoma cruzi and Leishmania donovani
    J K Stiles
    Department of Microbiology, Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, GA 303010, USA
    Ann Trop Med Parasitol 97:351-66. 2003
  6. ncbi request reprint The Trypanosoma cruzi genome contains ion motive ATPase genes which closely resemble Leishmania proton pumps
    J C Meade
    Department of Microbiology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216 4505, USA
    Parasitol Int 49:309-20. 2000
  7. ncbi request reprint High-level cerebellar expression of cytokines and adhesion molecules in fatal, paediatric, cerebral malaria
    H Armah
    Department of Pathology, University of Ghana Medical School, P O Box 4236, Accra, Ghana
    Ann Trop Med Parasitol 99:629-47. 2005
  8. pmc Immunolocalization and challenge studies using a recombinant Vibrio cholerae ghost expressing Trypanosoma brucei Ca(2+) ATPase (TBCA2) antigen
    Kiantra Ramey
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, Georgia 30310, USA
    Am J Trop Med Hyg 81:407-15. 2009
  9. ncbi request reprint Regulation of prohibitin expression during follicular development and atresia in the mammalian ovary
    Winston E Thompson
    Department of Obstetrics and Gynecology and Cooperative Reproductive Science Research Center, Morehouse School of Medicine, Atlanta, GA 30310, USA
    Biol Reprod 71:282-90. 2004
  10. ncbi request reprint Proinflammatory cytokines and the hypermetabolism of children with sickle cell disease
    Jacqueline M Hibbert
    Microbiology Biochemistry Immunology Pediatrics, Morehouse School of Medicine, 720 Westview Drive, S W, Atlanta, Georgia 30310 1495, USA
    Exp Biol Med (Maywood) 230:68-74. 2005

Collaborators

Detail Information

Publications21

  1. ncbi request reprint Trichomonas vaginalis: characterization of a family of P-type ATPase genes
    Preetam H Shah
    Department of Microbiology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216 4505, USA
    Parasitol Int 51:41-51. 2002
    ..RNA expression of the Trichomonas ATPases, except TVCA3, was constitutive over a range of environmental conditions. TVCA1, TVAPLT3 and TVPATP8 had the highest levels of RNA expression while TVAPLT1 and TVAPLT2 expression was the lowest...
  2. ncbi request reprint Apoptosis of rat granulosa cells after staurosporine and serum withdrawal is suppressed by adenovirus-directed overexpression of prohibitin
    Indrajit Chowdhury
    Department of Obstetrics and Gynecology, Morehouse School of Medicine, Atlanta, Georgia 30310, USA
    Endocrinology 148:206-17. 2007
    ..Furthermore, the prohibitin-eGFP fusion protein also inhibited programmed cell death. These results provide evidence that prohibitin could serve an antiapoptotic role in undifferentiated granulosa cells...
  3. ncbi request reprint Trypanosome apoptotic factor mediates apoptosis in human brain vascular endothelial cells
    Jonathan K Stiles
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, 720 Westview Dr S W, Atlanta, GA 30310 1495, USA
    Mol Biochem Parasitol 133:229-40. 2004
    ..Furthermore, this mAb blocked T. brucei- and ProEP2-1-induced apoptosis in HBVEC in vitro. We conclude that T. brucei TAF or its derivative(s) play a major role in the apoptosis associated with HAT pathology...
  4. ncbi request reprint Trypanosoma brucei infection induces apoptosis and up-regulates neuroleukin expression in the cerebellum
    J K Stiles
    Department of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, 720 Westview Dr S W, Atlanta, GA 30310 1495, USA
    Ann Trop Med Parasitol 95:797-810. 2001
    ..NLK may be modulating inflammation and is probably involved in protecting CN and the cerebellum against apoptosis...
  5. ncbi request reprint Identification of surface-membrane P-type ATPases resembling fungal K(+)- and Na(+)-ATPases, in Trypanosoma brucei, Trypanosoma cruzi and Leishmania donovani
    J K Stiles
    Department of Microbiology, Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, GA 303010, USA
    Ann Trop Med Parasitol 97:351-66. 2003
    ..Western blots probed with an antibody to the partial TBCA1 peptide identified a 150-kDa protein that was detected, by immunofluorescence, on the surface membrane of procyclic T. brucei...
  6. ncbi request reprint The Trypanosoma cruzi genome contains ion motive ATPase genes which closely resemble Leishmania proton pumps
    J C Meade
    Department of Microbiology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216 4505, USA
    Parasitol Int 49:309-20. 2000
    ..An antibody that recognizes the 110-kDa Leishmania donovani proton pump cross-reacts with a 100-kDa protein in lysates of T. cruzi epimastigotes...
  7. ncbi request reprint High-level cerebellar expression of cytokines and adhesion molecules in fatal, paediatric, cerebral malaria
    H Armah
    Department of Pathology, University of Ghana Medical School, P O Box 4236, Accra, Ghana
    Ann Trop Med Parasitol 99:629-47. 2005
    ..In the present study, IL-1beta and TNF were only up-regulated in the brains of children with neurodegenerative lesions, whereas TGF-beta was present in all cases...
  8. pmc Immunolocalization and challenge studies using a recombinant Vibrio cholerae ghost expressing Trypanosoma brucei Ca(2+) ATPase (TBCA2) antigen
    Kiantra Ramey
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, Atlanta, Georgia 30310, USA
    Am J Trop Med Hyg 81:407-15. 2009
    ..Thus, immunization of mice produced robust parasite-specific antibodies but failed to protect mice against parasite challenge...
  9. ncbi request reprint Regulation of prohibitin expression during follicular development and atresia in the mammalian ovary
    Winston E Thompson
    Department of Obstetrics and Gynecology and Cooperative Reproductive Science Research Center, Morehouse School of Medicine, Atlanta, GA 30310, USA
    Biol Reprod 71:282-90. 2004
    ..It is likely that prohibitin may play an important role in determining the fate of these cells and eventual follicular destiny...
  10. ncbi request reprint Proinflammatory cytokines and the hypermetabolism of children with sickle cell disease
    Jacqueline M Hibbert
    Microbiology Biochemistry Immunology Pediatrics, Morehouse School of Medicine, 720 Westview Drive, S W, Atlanta, Georgia 30310 1495, USA
    Exp Biol Med (Maywood) 230:68-74. 2005
    ....
  11. pmc Detection of Plasmodium falciparum histidine-rich protein II in saliva of malaria patients
    Nana O Wilson
    Morehouse School of Medicine, Department of Microbiology, Biochemistry and Immunology, Atlanta, Georgia 30310, USA
    Am J Trop Med Hyg 78:733-5. 2008
    ..The specificity was 100% with no false positive for both plasma and saliva when compared with blood smear. Thus, rapid detection of PfHRP II antigen in saliva may be a useful non-invasive and cost-effective malaria diagnostic technique...
  12. pmc Antibody responses to the merozoite surface protein-1 complex in cerebral malaria patients in India
    Naomi W Lucchi
    Malaria Branch, Division of Parasitic Diseases, National Center for Zoonotic, Vector Borne and Enteric Diseases, Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Malar J 7:121. 2008
    ....
  13. ncbi request reprint Genomic organization, transcription, splicing and gene regulation in Leishmania
    J K Stiles
    Department of Microbiology, School of Medicine, University of Mississippi Medical Center, Jackson 39216, USA
    Ann Trop Med Parasitol 93:781-807. 1999
    ..The salient features as well as the supporting evidence for each topic are briefly reviewed...
  14. ncbi request reprint CCL5 modulates pneumococcal immunity and carriage
    Ravichandran Palaniappan
    Mercer University, Atlanta, GA 30341, USA
    J Immunol 176:2346-56. 2006
    ..These data suggest that CCL5 is an essential factor for the induction and maintenance of protective pneumococcal immunity...
  15. pmc Prohibitin silencing reverses stabilization of mitochondrial integrity and chemoresistance in ovarian cancer cells by increasing their sensitivity to apoptosis
    Rosalind C Gregory-Bass
    Department of Obstetrics and Gynecology, Cooperative Reproductive Research Center, Morehouse School of Medicine, Atlanta, GA 30310, USA
    Int J Cancer 122:1923-30. 2008
    ..Furthermore, silencing of the Phb1 gene expression may prove to be a valuable therapeutic approach for chemoresistant ovarian cancer by increasing sensitivity of cancer cells to apoptosis...
  16. ncbi request reprint The cerebral-malaria-associated expression of RANTES, CCR3 and CCR5 in post-mortem tissue samples
    B Y Sarfo
    Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, GA 30310 1495, USA
    Ann Trop Med Parasitol 98:297-303. 2004
  17. pmc Plasma interleukin-1beta concentration is associated with stroke in sickle cell disease
    Kwaku Asare
    Morehouse School of Medicine, Atlanta, GA 30310, USA
    Cytokine 49:39-44. 2010
    ..This result demonstrates a strong association of systemic inflammation with stroke development in HbSS via moderately increased plasma IL-1beta concentration, which is furthermore associated with a decreased likelihood of stroke in HbSS...
  18. pmc Soluble factors from Plasmodium falciparum-infected erythrocytes induce apoptosis in human brain vascular endothelial and neuroglia cells
    Nana O Wilson
    Department of Microbiology, Biochemistry and Immunology, Morehouse School of Medicine, 720 Westview Drive SW, Atlanta, GA 30310, USA
    Mol Biochem Parasitol 162:172-6. 2008
    ....
  19. pmc C-reactive protein and interleukin-6 are decreased in transgenic sickle cell mice fed a high protein diet
    David R Archer
    Emory University School of Medicine and the Aflac Cancer Center and Blood Disorders Service, Atlanta, GA 30322, USA
    J Nutr 138:1148-52. 2008
    ..Dietary L-arginine availability was investigated as a possible mechanism for increased nitric oxide production and consequent reduced inflammation...
  20. ncbi request reprint Expression and functional role of CCR9 in prostate cancer cell migration and invasion
    Shailesh Singh
    Morehouse School of Medicine, Atlanta, Georgia 30310, USA
    Clin Cancer Res 10:8743-50. 2004
    ..The current study evaluates the molecular mechanisms of CCL25 and CCR9 in prostate cancer cell migration and invasion...
  21. pmc Plasmodium yoelii 17XL infection up-regulates RANTES, CCR1, CCR3 and CCR5 expression, and induces ultrastructural changes in the cerebellum
    Bismark Y Sarfo
    Parasitology Unit, Noguchi Memorial Institute for Medical Research, University of Ghana, P O Box LG581, Legon, Accra, Ghana
    Malar J 4:63. 2005
    ..A murine malaria model was utilized to evaluate the role of this chemokine and its receptors in malaria...