Genomes and Genes

Kotb Abdelmohsen

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. Abdelmohsen K, Panda A, Kang M, Guo R, Kim J, Grammatikakis I, et al. 7SL RNA represses p53 translation by competing with HuR. Nucleic Acids Res. 2014;42:10099-111 pubmed publisher
    ..Our findings suggest that targeting 7SL may be effective in the treatment of cancers with reduced p53 levels. ..
  2. Abdelmohsen K, Gorospe M. RNA-binding protein nucleolin in disease. RNA Biol. 2012;9:799-808 pubmed publisher
    ..Here, we review the RNA-binding activities of nucleolin, its influence on gene expression patterns, and its impact upon diseases. We also discuss the rising interest in targeting nucleolin therapeutically. ..
  3. Panda A, Grammatikakis I, Yoon J, Abdelmohsen K. Posttranscriptional regulation of insulin family ligands and receptors. Int J Mol Sci. 2013;14:19202-29 pubmed publisher
    ..Due to the pathological impacts of insulin system, we also discussed the possibilities of discovering new potential regulators which will improve understanding of insulin system and associated diseases. ..
  4. Panda A, Abdelmohsen K, Gorospe M. SASP regulation by noncoding RNA. Mech Ageing Dev. 2017;: pubmed publisher
    ..Here, we review the microRNAs, lncRNAs, and circRNAs that influence the production of SASP factors and discuss the rising interest in SASP-regulatory ncRNAs as diagnostic and therapeutic targets. ..
  5. Munk R, Panda A, Grammatikakis I, Gorospe M, Abdelmohsen K. Senescence-Associated MicroRNAs. Int Rev Cell Mol Biol. 2017;334:177-205 pubmed publisher
    ..Here, we review senescence-associated (SA)-MicroRNAs and discuss their implications in senescence-relevant pathologies. ..

Detail Information

Publications5

  1. Abdelmohsen K, Panda A, Kang M, Guo R, Kim J, Grammatikakis I, et al. 7SL RNA represses p53 translation by competing with HuR. Nucleic Acids Res. 2014;42:10099-111 pubmed publisher
    ..Our findings suggest that targeting 7SL may be effective in the treatment of cancers with reduced p53 levels. ..
  2. Abdelmohsen K, Gorospe M. RNA-binding protein nucleolin in disease. RNA Biol. 2012;9:799-808 pubmed publisher
    ..Here, we review the RNA-binding activities of nucleolin, its influence on gene expression patterns, and its impact upon diseases. We also discuss the rising interest in targeting nucleolin therapeutically. ..
  3. Panda A, Grammatikakis I, Yoon J, Abdelmohsen K. Posttranscriptional regulation of insulin family ligands and receptors. Int J Mol Sci. 2013;14:19202-29 pubmed publisher
    ..Due to the pathological impacts of insulin system, we also discussed the possibilities of discovering new potential regulators which will improve understanding of insulin system and associated diseases. ..
  4. Panda A, Abdelmohsen K, Gorospe M. SASP regulation by noncoding RNA. Mech Ageing Dev. 2017;: pubmed publisher
    ..Here, we review the microRNAs, lncRNAs, and circRNAs that influence the production of SASP factors and discuss the rising interest in SASP-regulatory ncRNAs as diagnostic and therapeutic targets. ..
  5. Munk R, Panda A, Grammatikakis I, Gorospe M, Abdelmohsen K. Senescence-Associated MicroRNAs. Int Rev Cell Mol Biol. 2017;334:177-205 pubmed publisher
    ..Here, we review senescence-associated (SA)-MicroRNAs and discuss their implications in senescence-relevant pathologies. ..