Affiliation: National Institutes of Health
- Abdelmohsen K, Panda A, Kang M, Guo R, Kim J, Grammatikakis I, et al. 7SL RNA represses p53 translation by competing with HuR. Nucleic Acids Res. 2014;42:10099-111 pubmed publisher..Our findings suggest that targeting 7SL may be effective in the treatment of cancers with reduced p53 levels. ..
- Abdelmohsen K, Gorospe M. RNA-binding protein nucleolin in disease. RNA Biol. 2012;9:799-808 pubmed publisher..Here, we review the RNA-binding activities of nucleolin, its influence on gene expression patterns, and its impact upon diseases. We also discuss the rising interest in targeting nucleolin therapeutically. ..
- Panda A, Grammatikakis I, Yoon J, Abdelmohsen K. Posttranscriptional regulation of insulin family ligands and receptors. Int J Mol Sci. 2013;14:19202-29 pubmed publisher..Due to the pathological impacts of insulin system, we also discussed the possibilities of discovering new potential regulators which will improve understanding of insulin system and associated diseases. ..
- Panda A, Abdelmohsen K, Gorospe M. SASP regulation by noncoding RNA. Mech Ageing Dev. 2017;: pubmed publisher..Here, we review the microRNAs, lncRNAs, and circRNAs that influence the production of SASP factors and discuss the rising interest in SASP-regulatory ncRNAs as diagnostic and therapeutic targets. ..
- Munk R, Panda A, Grammatikakis I, Gorospe M, Abdelmohsen K. Senescence-Associated MicroRNAs. Int Rev Cell Mol Biol. 2017;334:177-205 pubmed publisher..Here, we review senescence-associated (SA)-MicroRNAs and discuss their implications in senescence-relevant pathologies. ..