Mary Ellen Perry

Summary

Affiliation: National Institutes of Health
Country: USA

Publications

  1. ncbi request reprint Mdm2 in the response to radiation
    Mary Ellen Perry
    Division of Cancer Biology and Regulation of Protein Function Laboratory, National Cancer Institute, 6130 Executive Boulevard, Room 5034, Bethesda, MD 20892, USA
    Mol Cancer Res 2:9-19. 2004
  2. ncbi request reprint Highlights of the National Cancer Institute Workshop on mitochondrial function and cancer
    Mary Ellen Perry
    Division of Cancer Biology, National Cancer Institute, NIH, Bethesda, Maryland, USA
    Cancer Res 64:7640-4. 2004
  3. pmc The regulation of the p53-mediated stress response by MDM2 and MDM4
    Mary Ellen Perry
    Laboratory of Protein Dynamics and Signaling, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 0189, USA
    Cold Spring Harb Perspect Biol 2:a000968. 2010
  4. pmc mdm2 Is critical for inhibition of p53 during lymphopoiesis and the response to ionizing irradiation
    Susan M Mendrysa
    Department of Oncology, School of Medicine Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin 53706, USA
    Mol Cell Biol 23:462-72. 2003
  5. pmc Mdm2 regulates p53 independently of p19(ARF) in homeostatic tissues
    Kathleen A O'Leary
    Department of Oncology, University of Wisconsin, Madison, Wisconsin 53706, USA
    Mol Cell Biol 24:186-91. 2004
  6. ncbi request reprint Tumor suppression by p53 without accelerated aging: just enough of a good thing?
    Susan M Mendrysa
    Department of Basic Medical Sciences, Purdue University, West Lafayette, Indiana, USA
    Cell Cycle 5:714-7. 2006

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Mdm2 in the response to radiation
    Mary Ellen Perry
    Division of Cancer Biology and Regulation of Protein Function Laboratory, National Cancer Institute, 6130 Executive Boulevard, Room 5034, Bethesda, MD 20892, USA
    Mol Cancer Res 2:9-19. 2004
    ..Thus, Mdm2 is a potential target for therapeutic intervention because its inhibition may radiosensitize the subset of human tumors expressing wild-type p53 such that radiotherapy is more efficacious...
  2. ncbi request reprint Highlights of the National Cancer Institute Workshop on mitochondrial function and cancer
    Mary Ellen Perry
    Division of Cancer Biology, National Cancer Institute, NIH, Bethesda, Maryland, USA
    Cancer Res 64:7640-4. 2004
  3. pmc The regulation of the p53-mediated stress response by MDM2 and MDM4
    Mary Ellen Perry
    Laboratory of Protein Dynamics and Signaling, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892 0189, USA
    Cold Spring Harb Perspect Biol 2:a000968. 2010
    ....
  4. pmc mdm2 Is critical for inhibition of p53 during lymphopoiesis and the response to ionizing irradiation
    Susan M Mendrysa
    Department of Oncology, School of Medicine Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin 53706, USA
    Mol Cell Biol 23:462-72. 2003
    ..Furthermore, reduction of mdm2 in vivo resulted in radiosensitivity, highlighting the importance of mdm2 as a potential target for adjuvant cancer therapies...
  5. pmc Mdm2 regulates p53 independently of p19(ARF) in homeostatic tissues
    Kathleen A O'Leary
    Department of Oncology, University of Wisconsin, Madison, Wisconsin 53706, USA
    Mol Cell Biol 24:186-91. 2004
    ..Moreover, the Mdm2/p53/p19(ARF) pathway appears to exist only under very restricted conditions...
  6. ncbi request reprint Tumor suppression by p53 without accelerated aging: just enough of a good thing?
    Susan M Mendrysa
    Department of Basic Medical Sciences, Purdue University, West Lafayette, Indiana, USA
    Cell Cycle 5:714-7. 2006
    ..We raise the possibility that activation of p53 remains a promising strategy for cancer chemoprevention and therapy even if, under some circumstances, p53 might accelerate aging...