Cheryl Ann Lobo
Affiliation: New York Blood Center
- Glycophorin C is the receptor for the Plasmodium falciparum erythrocyte binding ligand PfEBP-2 (baebl)Cheryl Ann Lobo
Department of Molecular Parasitology, The Lindsley Kimball Research Institute, New York Blood Center, NY, NY 10021
Blood 101:4628-31. 2003..Thus PfEBP-2 is involved in a sialic acid-dependent pathway of invasion, which does not involve glycophorin A or glycophorin B and represents a novel route of entry into the RBCs...
- Characterization of PfRhop148, a novel rhoptry protein of Plasmodium falciparumCheryl Ann Lobo
Department of Molecular Parasitology, The Lindsley Kimball Research Institute, New York Blood Center, 310 E 67th St, New York, NY 10021, USA
Mol Biochem Parasitol 128:59-65. 2003..IFA and immunoelectron microscopic analyses revealed a rhoptry localization for the protein. The role of this protein in invasion and its relationship to the RhopH complex is now under further investigation...
- A malaria vaccine candidate based on an epitope of the Plasmodium falciparum RH5 proteinRosalynn L Ord
Department of Blood Borne Parasites, New York Blood Center, New York, NY 10065, USA
Malar J 13:326. 2014..However, the exact regions within PfRH5 that are targets of this invasion-inhibitory activity have yet to be identified...
- Targeting sialic acid dependent and independent pathways of invasion in Plasmodium falciparumRosalynn Louise Ord
Department of Blood Borne Parasites, New York Blood Center, New York, New York, United States of America
PLoS ONE 7:e30251. 2012..Results obtained show promise for the potential use of such hybrid vaccines to induce antibodies that can block multiple parasite ligand-red cell receptor interactions and thus inhibit parasite invasion...
- PfRH5: a novel reticulocyte-binding family homolog of plasmodium falciparum that binds to the erythrocyte, and an investigation of its receptorMarilis Rodriguez
Laboratory of Blood Borne Parasites, Lindsley Kimball Research Institute, The New York Blood Center, New York, New York, USA
PLoS ONE 3:e3300. 2008..Thus, we have shown that PfRH5 is a novel erythrocyte-binding ligand and the identification and partial characterization of the new RBC receptor may indicate the existence of an unrecognized P. falciparum invasion pathway...
- Anti-Plasmodium falciparum invasion ligand antibodies in a low malaria transmission region, Loreto, PeruElizabeth Villasis
Malaria Laboratory, Instituto de Medicina Tropical Alexander von Humboldt, Universidad Peruana Cayetano Heredia, Lima, Peru
Malar J 11:361. 2012....
- Babesia and red cell invasionCheryl A Lobo
Laboratory of Blood Borne Parasites, Lindsley Kimball Research Institute, New York Blood Center, New York 10021, USA
Curr Opin Hematol 19:170-5. 2012..The objective of this review is to present up-to-date information on both parasite and red blood cell molecules that function at the host-parasite interface to facilitate successful invasion...
- Associations between defined polymorphic variants in the PfRH ligand family and the invasion pathways used by P. falciparum field isolates from BrazilCheryl Ann Lobo
Molecular Parasitology, LFKRI, New York Blood Center, New York, NY 10021, USA
Mol Biochem Parasitol 149:246-51. 2006
- Babesia divergens and Plasmodium falciparum use common receptors, glycophorins A and B, to invade the human red blood cellCheryl Ann Lobo
Mailing address Molecular Parasitology, Lindsley Kimball Research Institute, New York Blood Center, 310 E 67th St, New York, NY 10021, USA
Infect Immun 73:649-51. 2005..divergens...
- Invasion profiles of Brazilian field isolates of Plasmodium falciparum: phenotypic and genotypic analysesCheryl Ann Lobo
Molecular Parasitology, Lindsley Kimball Research Institute, New York Blood Center, New York, New York 10021, USA
Infect Immun 72:5886-91. 2004..These studies have further confirmed the existence of a significant diversity of invasion pathways in nature and suggest that additional parasite ligands will have to be targeted to devise global vaccines that will work in the field...