Genomes and Genes
Affiliation: Northwestern University
- Expression and functional analysis of the Wnt/beta-catenin induced mir-135a-2 locus in embryonic forebrain developmentGiuliana Caronia-Brown
Department of Neurology and Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, 7 113 Lurie Bldg, 303 E Superior Street, Chicago, IL, 60611, USA
Neural Dev 11:9. 2016..Here, we investigated the role of miR-135a, derived from the mir-135a-2 locus, in embryonic forebrain development...
- An Lmx1b-miR135a2 regulatory circuit modulates Wnt1/Wnt signaling and determines the size of the midbrain dopaminergic progenitor poolAngela Anderegg
Northwestern University Feinberg School of Medicine, Department of Neurology and Center for Genetic Medicine, Chicago, Illinois, United States of America
PLoS Genet 9:e1003973. 2013..Since canonical Wnt activity has recently been recognized as a key ingredient for programming ESCs towards a dopaminergic fate in vitro, these studies could impact the rational design of such protocols. ..
- The cortical hem regulates the size and patterning of neocortexGiuliana Caronia-Brown
Department of Neurobiology, University of Chicago, Chicago, IL 60637, USA
Development 141:2855-65. 2014..Our findings reveal a much broader role for the hem in cortical development than previously recognized, and emphasize that two major signaling centers interact antagonistically to pattern cerebral cortex. ..