M A Sanchez

Summary

Affiliation: Oregon Health and Science University
Country: USA

Publications

  1. ncbi request reprint Cloning and functional expression of a gene encoding a P1 type nucleoside transporter from Trypanosoma brucei
    M A Sanchez
    Department of Molecular Microbiology, Oregon Health Sciences University, Portland, Oregon 97201, USA
    J Biol Chem 274:30244-9. 1999
  2. ncbi request reprint Molecular genetic analysis of purine nucleobase transport in Leishmania major
    Diana Ortiz
    Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR 97239, USA
    Mol Microbiol 64:1228-43. 2007
  3. pmc Molecular identification and characterization of an essential pyruvate transporter from Trypanosoma brucei
    Marco A Sanchez
    Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Biol Chem 288:14428-37. 2013
  4. pmc Arsenic transport by zebrafish aquaglyceroporins
    Mohamad Hamdi
    Dept of Biological Sciences, Oakland University, Rochester, MI 48309, USA
    BMC Mol Biol 10:104. 2009
  5. ncbi request reprint A novel purine nucleoside transporter whose expression is up-regulated in the short stumpy form of the Trypanosoma brucei life cycle
    Marco A Sanchez
    Department of Molecular Microbiology and Immunology, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, L220, Portland, OR 97239, USA
    Mol Biochem Parasitol 136:265-72. 2004
  6. ncbi request reprint Functional expression and characterization of a purine nucleobase transporter gene from Leishmania major
    Marco A Sanchez
    Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR 97201, USA
    Mol Membr Biol 21:11-8. 2004
  7. ncbi request reprint Six related nucleoside/nucleobase transporters from Trypanosoma brucei exhibit distinct biochemical functions
    Marco A Sanchez
    Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, Oregon 97201, USA
    J Biol Chem 277:21499-504. 2002
  8. pmc Nucleoside and nucleobase transporters in parasitic protozoa
    Scott M Landfear
    Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    Eukaryot Cell 3:245-54. 2004
  9. ncbi request reprint Molecular and functional characterization of the first nucleobase transporter gene from African trypanosomes
    Cristina Henriques
    Department of Molecular Microbiology and Immunology, Oregon Health and Science University, 3181 S W Sam Jackson Park Road, Portland, OR 97201, USA
    Mol Biochem Parasitol 130:101-10. 2003
  10. pmc Mammalian glucose permease GLUT1 facilitates transport of arsenic trioxide and methylarsonous acid
    Zijuan Liu
    Department of Biochemistry and Molecular Biology, Wayne State University, School of Medicine, Detroit, MI 48201, USA
    Biochem Biophys Res Commun 351:424-30. 2006

Collaborators

  • B P Rosen
  • Scott M Landfear
  • Zijuan Liu
  • Mohamad Hamdi
  • Diana Ortiz
  • Cristina Henriques
  • Qianyong Liu
  • Lauren C Beene
  • Steven Pierce
  • Timo Herrmann
  • H G Archie Bouwer
  • Nicola Kimblin
  • Xuan Jiang
  • Eckhard Boles
  • Nicola S Carter
  • Buddy Ullman
  • Rob Tryon

Detail Information

Publications10

  1. ncbi request reprint Cloning and functional expression of a gene encoding a P1 type nucleoside transporter from Trypanosoma brucei
    M A Sanchez
    Department of Molecular Microbiology, Oregon Health Sciences University, Portland, Oregon 97201, USA
    J Biol Chem 274:30244-9. 1999
    ..Genomic Southern blots suggest that there are multiple genes related in sequence to TbNT2, implying the existence of a family of nucleoside transporter genes in these parasites...
  2. ncbi request reprint Molecular genetic analysis of purine nucleobase transport in Leishmania major
    Diana Ortiz
    Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR 97239, USA
    Mol Microbiol 64:1228-43. 2007
    ..The phenotypes of these null mutants underscore the importance of purine nucleobase transporters in the Leishmania life cycle and pharmacology...
  3. pmc Molecular identification and characterization of an essential pyruvate transporter from Trypanosoma brucei
    Marco A Sanchez
    Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Biol Chem 288:14428-37. 2013
    ..The discovery of TbPT0 reveals for the first time the identity of the essential pyruvate transporter and provides a potential drug target against the mammalian life cycle stage of T. brucei...
  4. pmc Arsenic transport by zebrafish aquaglyceroporins
    Mohamad Hamdi
    Dept of Biological Sciences, Oakland University, Rochester, MI 48309, USA
    BMC Mol Biol 10:104. 2009
    ..Members of the aquaglyceroporin family have been shown to actively conduct AsIII and its organic metabolite, monomethylarsenite (MAsIII). However, the transport of AsIII and MAsIII in in any fish species has not been characterized...
  5. ncbi request reprint A novel purine nucleoside transporter whose expression is up-regulated in the short stumpy form of the Trypanosoma brucei life cycle
    Marco A Sanchez
    Department of Molecular Microbiology and Immunology, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, L220, Portland, OR 97239, USA
    Mol Biochem Parasitol 136:265-72. 2004
    ....
  6. ncbi request reprint Functional expression and characterization of a purine nucleobase transporter gene from Leishmania major
    Marco A Sanchez
    Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR 97201, USA
    Mol Membr Biol 21:11-8. 2004
    ..5, 8.5 +/- 0.6, 8.5 +/- 1.1, and 8.8 +/- 4.0 microM, respectively. LmaNT3 is, thus, the first member of the ENT family identified in any organism that functions as a nucleobase rather than nucleoside or nucleoside/nucleobase transporter...
  7. ncbi request reprint Six related nucleoside/nucleobase transporters from Trypanosoma brucei exhibit distinct biochemical functions
    Marco A Sanchez
    Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, Oregon 97201, USA
    J Biol Chem 277:21499-504. 2002
    ..These results demonstrate that T. brucei expresses multiple purine transporters with distinct substrate specificities and different patterns of expression during the parasite life cycle...
  8. pmc Nucleoside and nucleobase transporters in parasitic protozoa
    Scott M Landfear
    Department of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, Oregon 97239 3098, USA
    Eukaryot Cell 3:245-54. 2004
  9. ncbi request reprint Molecular and functional characterization of the first nucleobase transporter gene from African trypanosomes
    Cristina Henriques
    Department of Molecular Microbiology and Immunology, Oregon Health and Science University, 3181 S W Sam Jackson Park Road, Portland, OR 97201, USA
    Mol Biochem Parasitol 130:101-10. 2003
    ..1 mRNA is significantly more abundant in insect stage procyclic forms than in mammalian stage bloodstream forms, and the TbNT8.1 permease thus may represent a major route for purine nucleobase uptake in procyclic trypanosomes...
  10. pmc Mammalian glucose permease GLUT1 facilitates transport of arsenic trioxide and methylarsonous acid
    Zijuan Liu
    Department of Biochemistry and Molecular Biology, Wayne State University, School of Medicine, Detroit, MI 48201, USA
    Biochem Biophys Res Commun 351:424-30. 2006
    ..Thus GLUT1 may be a major pathway uptake of both inorganic and methylated arsenicals in erythrocytes or the epithelial cells of the blood-brain barrier, contributing to arsenic-related cardiovascular problems and neurotoxicity...