Xiaoqi Liu

Summary

Affiliation: Purdue University
Country: USA

Publications

  1. request reprint
    Liu X, Erikson R. The nuclear localization signal of mitotic kinesin-like protein Mklp-1: effect on Mklp-1 function during cytokinesis. Biochem Biophys Res Commun. 2007;353:960-4 pubmed
    ..Furthermore, mutation of two serine residues in the first NLS to aspartic acid, which mimics phosphorylation, attenuated its nuclear localization function, suggesting that the function of this NLS might be regulated by phosphorylation. ..
  2. Li Z, Shao C, Kong Y, Carlock C, Ahmad N, Liu X. DNA Damage Response-Independent Role for MDC1 in Maintaining Genomic Stability. Mol Cell Biol. 2017;37: pubmed publisher
    ..Our results demonstrate that MDC1 also plays a fundamentally significant role in maintenance of genomic stability through a DDR-independent pathway. ..
  3. Li Z, Li J, Kong Y, Yan S, Ahmad N, Liu X. Plk1 Phosphorylation of Mre11 Antagonizes the DNA Damage Response. Cancer Res. 2017;77:3169-3180 pubmed publisher
    ..i>Cancer Res; 77(12); 3169-80. ©2017 AACR. ..
  4. Li Z, Liu J, Li J, Kong Y, Sandusky G, Rao X, et al. Polo-like kinase 1 (Plk1) overexpression enhances ionizing radiation-induced cancer formation in mice. J Biol Chem. 2017;292:17461-17472 pubmed publisher
    ..We conclude that Plk1 overexpression may contribute to tumor formation by both inducing chromosomal instability and suppressing the DDR pathway. ..

Locale

Detail Information

Publications4

  1. request reprint
    Liu X, Erikson R. The nuclear localization signal of mitotic kinesin-like protein Mklp-1: effect on Mklp-1 function during cytokinesis. Biochem Biophys Res Commun. 2007;353:960-4 pubmed
    ..Furthermore, mutation of two serine residues in the first NLS to aspartic acid, which mimics phosphorylation, attenuated its nuclear localization function, suggesting that the function of this NLS might be regulated by phosphorylation. ..
  2. Li Z, Shao C, Kong Y, Carlock C, Ahmad N, Liu X. DNA Damage Response-Independent Role for MDC1 in Maintaining Genomic Stability. Mol Cell Biol. 2017;37: pubmed publisher
    ..Our results demonstrate that MDC1 also plays a fundamentally significant role in maintenance of genomic stability through a DDR-independent pathway. ..
  3. Li Z, Li J, Kong Y, Yan S, Ahmad N, Liu X. Plk1 Phosphorylation of Mre11 Antagonizes the DNA Damage Response. Cancer Res. 2017;77:3169-3180 pubmed publisher
    ..i>Cancer Res; 77(12); 3169-80. ©2017 AACR. ..
  4. Li Z, Liu J, Li J, Kong Y, Sandusky G, Rao X, et al. Polo-like kinase 1 (Plk1) overexpression enhances ionizing radiation-induced cancer formation in mice. J Biol Chem. 2017;292:17461-17472 pubmed publisher
    ..We conclude that Plk1 overexpression may contribute to tumor formation by both inducing chromosomal instability and suppressing the DDR pathway. ..