K Augustine

Summary

Affiliation: SmithKline Beecham Pharmaceuticals
Country: USA

Publications

  1. ncbi Antisense approaches for investigating mechanisms of abnormal development
    K Augustine
    Department of Cell Biology, Amgen, Inc, Thousand Oaks, CA 91320 1789, USA
    Mutat Res 396:175-93. 1997
  2. ncbi Rodent mutant models of obesity and their correlations to human obesity
    K A Augustine
    SmithKline Beecham Pharmaceuticals, Department of Reproductive Toxicology, King of Prussia, PA 19406, USA
    Anat Rec 257:64-72. 1999
  3. ncbi Noninsulin-dependent diabetes mellitus occurs in mice ectopically expressing the human Axl tyrosine kinase receptor
    K A Augustine
    Department of Cell Biology, Amgen, Inc, Thosand Oaks, California, USA
    J Cell Physiol 181:433-47. 1999
  4. ncbi Protein tyrosine phosphatase (PC12, Br7,S1) family: expression characterization in the adult human and mouse
    K A Augustine
    Department of Cell Biology, Amgen, Inc, Thousand Oaks, California 91320, USA
    Anat Rec 258:221-34. 2000
  5. ncbi Evidence that the protein tyrosine phosphatase (PC12,Br7,Sl) gamma (-) isoform modulates chondrogenic patterning and growth
    K A Augustine
    Department of Cell Biology, Amgen Center, California, USA
    Int J Dev Biol 44:361-71. 2000
  6. ncbi Antisense inhibition of engrailed genes in mouse embryos reveals roles for these genes in craniofacial and neural tube development
    K A Augustine
    Department of Cell Biology and Anatomy, University of North Carolina at Chapel Hill 27599, USA
    Teratology 51:300-10. 1995
  7. ncbi Interactions of Wnt-1 and Wnt-3a are essential for neural tube patterning
    K A Augustine
    Department of Cell Biology and Anatomy, University of North Carolina at Chapel Hill 27599, USA
    Teratology 51:107-19. 1995

Collaborators

Detail Information

Publications7

  1. ncbi Antisense approaches for investigating mechanisms of abnormal development
    K Augustine
    Department of Cell Biology, Amgen, Inc, Thousand Oaks, CA 91320 1789, USA
    Mutat Res 396:175-93. 1997
    ..This review focuses on a comprehensive description of the characterized properties of oligodeoxynucleotides, control design, and various developmental in vitro approaches for accomplishing these studies in embryonic systems...
  2. ncbi Rodent mutant models of obesity and their correlations to human obesity
    K A Augustine
    SmithKline Beecham Pharmaceuticals, Department of Reproductive Toxicology, King of Prussia, PA 19406, USA
    Anat Rec 257:64-72. 1999
    ..In this review, we discuss the physiology and genetics underlying obesity and how studies in rodents and humans are converging, producing a greater understanding of the mechanisms underlying this health problem...
  3. ncbi Noninsulin-dependent diabetes mellitus occurs in mice ectopically expressing the human Axl tyrosine kinase receptor
    K A Augustine
    Department of Cell Biology, Amgen, Inc, Thosand Oaks, California, USA
    J Cell Physiol 181:433-47. 1999
    ....
  4. ncbi Protein tyrosine phosphatase (PC12, Br7,S1) family: expression characterization in the adult human and mouse
    K A Augustine
    Department of Cell Biology, Amgen, Inc, Thousand Oaks, California 91320, USA
    Anat Rec 258:221-34. 2000
    ..Furthermore, these restricted patterns suggest that the encoded family of phosphatases may play roles in modulating signal transduction pathways important for specific cell types and biological processes...
  5. ncbi Evidence that the protein tyrosine phosphatase (PC12,Br7,Sl) gamma (-) isoform modulates chondrogenic patterning and growth
    K A Augustine
    Department of Cell Biology, Amgen Center, California, USA
    Int J Dev Biol 44:361-71. 2000
    ..These studies provide evidence that in early skeletal development, PTPPBS gamma may regulate the rate of chondroblast proliferation in the cartilaginous skeleton...
  6. ncbi Antisense inhibition of engrailed genes in mouse embryos reveals roles for these genes in craniofacial and neural tube development
    K A Augustine
    Department of Cell Biology and Anatomy, University of North Carolina at Chapel Hill 27599, USA
    Teratology 51:300-10. 1995
    ..abstract truncated at 250 words)..
  7. ncbi Interactions of Wnt-1 and Wnt-3a are essential for neural tube patterning
    K A Augustine
    Department of Cell Biology and Anatomy, University of North Carolina at Chapel Hill 27599, USA
    Teratology 51:107-19. 1995
    ..Herein, we present data suggesting functional redundancy of Wnt-1 and Wnt-3a in neural tube patterning and in regulation of engrailed expression...