I C Solomon

Summary

Affiliation: State University of New York
Country: USA

Publications

  1. ncbi request reprint Time-frequency representation of inspiratory motor output in anesthetized C57BL/6 mice in vivo
    Marvin H O'Neal
    Deptartment of Physiology and Biophysics, State University of New York at Stony Brook, Basic Science Tower T6, Rm 140, Stony Brook, NY 11794 8661, USA
    J Neurophysiol 93:1762-75. 2005
  2. ncbi request reprint Chemical activation of pre-Bötzinger complex in vivo reduces respiratory network complexity
    Xinnian Chen
    Dept of Biomedical Engineering, Basic Science Tower T6 Rm 140, State Univ of New York at Stony Brook, Stony Brook, NY 11794 8661, USA
    Am J Physiol Regul Integr Comp Physiol 288:R1237-47. 2005
  3. ncbi request reprint CO(2)/H(+) chemoreception in the cat pre-Bötzinger complex in vivo
    I C Solomon
    Department of Physiology and Biophysics, State University of New York at Stony Brook, 11794 8661, USA
    J Appl Physiol (1985) 88:1996-2007. 2000
  4. ncbi request reprint Connexin36 distribution in putative CO2-chemosensitive brainstem regions in rat
    Irene C Solomon
    Department of Physiology and Biophysics, State University of New York at Stony Brook, Basic Science Tower, Health Science Center, Level 6, Rm 140, Stony Brook, NY 11794 8661, USA
    Respir Physiol Neurobiol 139:1-20. 2003
  5. ncbi request reprint Focal CO2/H+ alters phrenic motor output response to chemical stimulation of cat pre-Botzinger complex in vivo
    Irene C Solomon
    Department of Physiology and Biophysics, State University of New York at Stony Brook, Stony Brook, New York 11794 8661, USA
    J Appl Physiol (1985) 94:2151-7. 2003
  6. ncbi request reprint Glutamate neurotransmission is not required for, but may modulate, hypoxic sensitivity of pre-Bötzinger complex in vivo
    Irene C Solomon
    Deptartment of Physiology and Biophysics, State University of New York at Stony Brook, Basic Science Tower T6, Rm 140, Stony Brook, NY 11794 8661, USA
    J Neurophysiol 93:1278-84. 2005
  7. ncbi request reprint Influence of respiratory network drive on phrenic motor output evoked by activation of cat pre-Botzinger complex
    Irene C Solomon
    Department of Physiology and Biophysics, State University of New York at Stony Brook, Stony Brook, New York 11794 8661, USA
    Am J Physiol Regul Integr Comp Physiol 284:R455-66. 2003
  8. ncbi request reprint Blockade of brain stem gap junctions increases phrenic burst frequency and reduces phrenic burst synchronization in adult rat
    Irene C Solomon
    Department of Physiology and Biophysics, State University of New York, Stony Brook 11794 8661, USA
    J Neurophysiol 89:135-49. 2003
  9. ncbi request reprint Ionotropic excitatory amino acid receptors in pre-Botzinger complex play a modulatory role in hypoxia-induced gasping in vivo
    Irene C Solomon
    Department of Physiology and Biophysics, State University of New York at Stony Brook, Stony Brook, NY 11794 8661, USA
    J Appl Physiol (1985) 96:1643-50. 2004
  10. ncbi request reprint Gap junctions in CO(2)-chemoreception and respiratory control
    Irene C Solomon
    Department of Physiology and Biophysics, State University of New York at Stony Brook, Stony Brook, NY 11794 8661, USA
    Respir Physiol Neurobiol 131:155-73. 2002

Collaborators

Detail Information

Publications29

  1. ncbi request reprint Time-frequency representation of inspiratory motor output in anesthetized C57BL/6 mice in vivo
    Marvin H O'Neal
    Deptartment of Physiology and Biophysics, State University of New York at Stony Brook, Basic Science Tower T6, Rm 140, Stony Brook, NY 11794 8661, USA
    J Neurophysiol 93:1762-75. 2005
    ....
  2. ncbi request reprint Chemical activation of pre-Bötzinger complex in vivo reduces respiratory network complexity
    Xinnian Chen
    Dept of Biomedical Engineering, Basic Science Tower T6 Rm 140, State Univ of New York at Stony Brook, Stony Brook, NY 11794 8661, USA
    Am J Physiol Regul Integr Comp Physiol 288:R1237-47. 2005
    ..These observations demonstrate that activation of the pre-BötC reduces inspiratory network complexity, suggesting a role for the pre-BötC in regulation of complex respiratory dynamics...
  3. ncbi request reprint CO(2)/H(+) chemoreception in the cat pre-Bötzinger complex in vivo
    I C Solomon
    Department of Physiology and Biophysics, State University of New York at Stony Brook, 11794 8661, USA
    J Appl Physiol (1985) 88:1996-2007. 2000
    ....
  4. ncbi request reprint Connexin36 distribution in putative CO2-chemosensitive brainstem regions in rat
    Irene C Solomon
    Department of Physiology and Biophysics, State University of New York at Stony Brook, Basic Science Tower, Health Science Center, Level 6, Rm 140, Stony Brook, NY 11794 8661, USA
    Respir Physiol Neurobiol 139:1-20. 2003
    ..We propose that the gap junction protein Cx36 also contributes to the neuroanatomical substrate for gap junctional communication, which is hypothesized to play a role in central CO2 chemoreception...
  5. ncbi request reprint Focal CO2/H+ alters phrenic motor output response to chemical stimulation of cat pre-Botzinger complex in vivo
    Irene C Solomon
    Department of Physiology and Biophysics, State University of New York at Stony Brook, Stony Brook, New York 11794 8661, USA
    J Appl Physiol (1985) 94:2151-7. 2003
    ..Furthermore, these findings suggest that focal increases in pre-BötC CO(2)/H(+) may have contributed to the modulation of the DLH-induced responses previously observed during systemic hypercapnia...
  6. ncbi request reprint Glutamate neurotransmission is not required for, but may modulate, hypoxic sensitivity of pre-Bötzinger complex in vivo
    Irene C Solomon
    Deptartment of Physiology and Biophysics, State University of New York at Stony Brook, Basic Science Tower T6, Rm 140, Stony Brook, NY 11794 8661, USA
    J Neurophysiol 93:1278-84. 2005
    ..Thus these findings provide additional support to the concept of intrinsic hypoxic sensitivity of the pre-BötC...
  7. ncbi request reprint Influence of respiratory network drive on phrenic motor output evoked by activation of cat pre-Botzinger complex
    Irene C Solomon
    Department of Physiology and Biophysics, State University of New York at Stony Brook, Stony Brook, New York 11794 8661, USA
    Am J Physiol Regul Integr Comp Physiol 284:R455-66. 2003
    ....
  8. ncbi request reprint Blockade of brain stem gap junctions increases phrenic burst frequency and reduces phrenic burst synchronization in adult rat
    Irene C Solomon
    Department of Physiology and Biophysics, State University of New York, Stony Brook 11794 8661, USA
    J Neurophysiol 89:135-49. 2003
    ....
  9. ncbi request reprint Ionotropic excitatory amino acid receptors in pre-Botzinger complex play a modulatory role in hypoxia-induced gasping in vivo
    Irene C Solomon
    Department of Physiology and Biophysics, State University of New York at Stony Brook, Stony Brook, NY 11794 8661, USA
    J Appl Physiol (1985) 96:1643-50. 2004
    ..The present findings also provide additional support for the pre-BötC as the primary locus of respiratory rhythm generation...
  10. ncbi request reprint Gap junctions in CO(2)-chemoreception and respiratory control
    Irene C Solomon
    Department of Physiology and Biophysics, State University of New York at Stony Brook, Stony Brook, NY 11794 8661, USA
    Respir Physiol Neurobiol 131:155-73. 2002
    ..This review provides an overview of gap junction neurobiology in the mammalian CNS and presents the anatomical and electrophysiological evidence for gap junctions in CO(2) chemoreception and respiratory control...
  11. ncbi request reprint Modulation of expiratory motor output evoked by chemical activation of pre-Bötzinger complex in vivo
    Irene C Solomon
    Department of Physiology and Biophysics, State University of New York at Stony Brook, Stony Brook, NY 11794 8661, USA
    Respir Physiol Neurobiol 130:235-51. 2002
    ....
  12. ncbi request reprint Modulation of gasp frequency by activation of pre-Bötzinger complex in vivo
    Irene C Solomon
    Department of Physiology and Biophysics, State University of New York at Stony Brook, Stony Brook, NY 11794 8661, USA
    J Neurophysiol 87:1664-8. 2002
    ..These findings also provide additional support to the concept of intrinsic hypoxic chemosensitivity of the pre-BötC...
  13. ncbi request reprint Differential expression of connexin26 and connexin32 in the pre-Bötzinger complex of neonatal and adult rat
    I C Solomon
    Department of Physiology and Biophysics, State University of New York at Stony Brook, Stony Brook, New York 11794 8661, USA
    J Comp Neurol 440:12-9. 2001
    ....
  14. ncbi request reprint Localization of connexin26 and connexin32 in putative CO(2)-chemosensitive brainstem regions in rat
    I C Solomon
    Department of Physiology and Biophysics, State University of New York, Basic Science Tower, Health SC Center, Level 6, Rm 140, Stony Brook, NY 11794 8661, USA
    Respir Physiol 129:101-21. 2001
    ..We propose that the gap junction proteins Cx26 and Cx32, at least in part, form the neuroanatomical substrate for this gap junctional communication, which is hypothesized to play a role in central CO(2) chemoreception...
  15. ncbi request reprint Excitation of phrenic and sympathetic output during acute hypoxia: contribution of medullary oxygen detectors
    I C Solomon
    Department of Physiology and Biophysics, Health Sciences Center, Basic Science Tower, Level 6, Room 140, State University of New York at Stony Brook, Stony Brook, NY 11794 8661, USA
    Respir Physiol 121:101-17. 2000
    ....
  16. ncbi request reprint Glutamatergic neurotransmission is not essential for, but plays a modulatory role in, the production of gasping in arterially-perfused adult rat
    Kelly A Warren
    SUNY at Stony Brook, Department of Physiology and Biophysics, USA
    Adv Exp Med Biol 605:423-7. 2008
    ....
  17. doi request reprint Influence of extracellular [K+]o on inspiratory network complexity of phrenic and hypoglossal nerve discharge in arterially-perfused adult rat
    Tabitha Y Shen
    Department of Physiology and Biophysics, Stony Brook University, Stony Brook, NY, USA
    Adv Exp Med Biol 669:181-4. 2010
    ....
  18. doi request reprint Influence of 5-HT2A receptor blockade on phrenic nerve discharge at three levels of extracellular K+ in arterially-perfused adult rat
    Tejus A Bale
    Department of Physiology and Biophysics, Stony Brook University, New York, USA
    Adv Exp Med Biol 669:139-42. 2010
    ..These data support an important role for 5-HT(2A) receptors in respiratory control, and indicate the their role is not dependent on the level of [K(+)](o)...
  19. doi request reprint Geometrical analysis of bursting pacemaker neurons generated by computational models: comparison to in vitro pre-Bötzinger complex bursting neurons
    Juan M Cordovez
    Department of Physiology and Biophysics, Stony Brook University, Stony Brook, NY, USA
    Adv Exp Med Biol 669:45-8. 2010
    ..Based on our observations, we identify one of the models to better represent the general characteristics of the bursting dynamics and propose additional modifications to better capture the dynamics of our own experimental recordings...
  20. ncbi request reprint Burst-to-Burst variability in respiratory timing, inspiratory-phase spectral activity, and inspiratory neural network complexity in urethane-anesthetized C57BL/6 mice in vivo
    Hyun Hye Chun
    Stony Brook University, Graduate Program in Neuroscience, USA
    Adv Exp Med Biol 605:407-12. 2008
    ..All measures were assessed by quantitative poincaré plot analyses and the determination of the coefficient of variation...
  21. ncbi request reprint Fast oscillatory rhythms in inspiratory motor discharge: a mathematical model
    Xinnian Chen
    SUNY at Stony Brook, Department of Physiology and Biophysics, USA
    Adv Exp Med Biol 605:401-6. 2008
    ....
  22. ncbi request reprint Respiratory network complexity in neonatal rat in vivo and in vitro
    Hui Jing Yu
    State University of New York at Stony Brook, Department of Physiology and Biophysics, USA
    Adv Exp Med Biol 605:393-8. 2008
    ..We suggest that additional studies be conducted to identify the precise mechanisms responsible for the differences in central inspiratory neural network complexity between these two neonatal rat preparations...
  23. ncbi request reprint A mathematical model of pH(i) regulation in central CO2- chemoreception
    Juan M Cordovez
    State University of New York at Stony Brook, Department of Physiology and Biophysics, USA
    Adv Exp Med Biol 605:306-11. 2008
    ..Here, we compare the results of two different formulations of a mathematical model to begin to explore pH(i) regulation in central CO2 chemoreception...
  24. ncbi request reprint Differences in pHi recovery in CO2-chemosensitive and non-chemosensitive cells: predictions from a mathematical model
    Juan M Cordovez
    Department of Biomedical Engineering, Stony Brook University, Stony Brook, NY 11794 USA
    Conf Proc IEEE Eng Med Biol Soc . 2006
    ..The model suggests that differences in pHi regulation may be dependent upon differences in the activation set-point of the internal modifier site of the Na(+)/H(+) exchanger (NHE)...
  25. ncbi request reprint Fast oscillatory rhythms in inspiratory motor discharge: a mathematical model
    Xinnian Chen
    Dept of Biomed Eng, Stony Brook Univ, NY 11794, USA
    Conf Proc IEEE Eng Med Biol Soc 1:4619-22. 2006
    ....
  26. ncbi request reprint Role of gap junctions in CO(2) chemoreception and respiratory control
    Jay B Dean
    Department of Physiology and Biophysics, Environmental and Hyperbaric Cell Biology Facility, Wright State University, Dayton, Ohio 45435, USA
    Am J Physiol Lung Cell Mol Physiol 283:L665-70. 2002
    ..Specific research questions related to the role of gap junctions in respiratory control are suggested for future research...
  27. doi request reprint Upper airway and abdominal motor output during sneezing: is the in vivo decererate rat an adequate model?
    Kenichi Ono
    Department of Physiology and Biophysics, Stony Brook University, Stony Brook, NY, USA
    Adv Exp Med Biol 669:173-6. 2010
    ..We suggest that the in vivo decerebrate rat is an acceptable model for studying the sneezing reflex...
  28. ncbi request reprint CO2 transduction in avian intrapulmonary chemoreceptors is critically dependent on transmembrane Na+/H+ exchange
    Steven C Hempleman
    Department of Biological Sciences, Northern Arizona University, Flagstaff, Arizona 86011 5640, USA
    Am J Physiol Regul Integr Comp Physiol 284:R1551-9. 2003
    ..07). Taken together, these findings suggest that CO(2) transduction in IPC is dependent on transmembrane NHE although it is likely to be much slower than carbonic anhydrase-catalyzed hydration-dehydration of CO(2)...
  29. doi request reprint Automatic selection of the threshold value R for approximate entropy
    Sheng Lu
    Department of Biomedical Engineering, State University of New York SUNY Stony Brook, NY 11794, USA
    IEEE Trans Biomed Eng 55:1966-72. 2008
    ..Application to both synthetic and experimental data confirmed the advantages claimed with the proposed approach...