D R Allred

Summary

Affiliation: University of Florida
Country: USA

Publications

  1. ncbi request reprint Antigenic variation and cytoadhesion in Babesia bovis and Plasmodium falciparum: different logics achieve the same goal
    David R Allred
    Department of Pathobiology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32611 0880, USA
    Mol Biochem Parasitol 134:27-35. 2004
  2. ncbi request reprint Babesiosis: persistence in the face of adversity
    David R Allred
    Dept of Pathobiology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32611 0880, USA
    Trends Parasitol 19:51-5. 2003
  3. ncbi request reprint Antigenic variation in babesiosis: is there more than one 'why'?
    D R Allred
    Department of Pathobiology, University of Florida, Gainesville, FL 32611 0880, USA
    Microbes Infect 3:481-91. 2001
  4. ncbi request reprint The ves multigene family of B. bovis encodes components of rapid antigenic variation at the infected erythrocyte surface
    D R Allred
    Department of Pathobiology, University of Florida, Gainesville 32611, USA
    Mol Cell 5:153-62. 2000
  5. ncbi request reprint Antigenic variation in Babesia bovis: how similar is it to that in Plasmodium falciparum?
    D R Allred
    Department of Pathobiology, College of Veterinary Medicine, University of Florida, Gainesville 32611 0880, USA
    Ann Trop Med Parasitol 92:461-72. 1998
  6. ncbi request reprint Immunochemical methods for identification of Babesia bovis antigens expressed on the erythrocyte surface
    D R Allred
    Department of Pathobiology, College of Veterinary Medicine, University of Florida, Gainesville, Florida, 32611 0880, USA
    Methods 13:177-89. 1997
  7. ncbi request reprint Dynamics of anemia progression and recovery in Babesia bigemina infection is unrelated to initiating parasite burden
    David R Allred
    University of Florida, Department of Infectious Diseases and Pathology, P O Box 110880, Gainesville, FL 32611 0880, USA
    Vet Parasitol 146:170-4. 2007
  8. ncbi request reprint Molecular technology and antigenic variation among intraerythrocytic hemoparasites: do we see reality?
    D R Allred
    Department of Pathobiology, University of Florida, P O Box 110880, Gainesville, FL 32611 0880, USA
    Vet Parasitol 101:261-74. 2001
  9. ncbi request reprint Antigenic variation in Babesia bovis occurs through segmental gene conversion of the ves multigene family, within a bidirectional locus of active transcription
    Basima Al-Khedery
    Department of Pathobiology, University of Florida, Gainesville, 32611, USA
    Mol Microbiol 59:402-14. 2006
  10. ncbi request reprint Antigenic variation as an exploitable weakness of babesial parasites
    David R Allred
    Department of Pathobiology, University of Florida, Gainesville, FL 32611 0880, USA
    Vet Parasitol 138:50-60. 2006

Collaborators

  • Basima Al Khedery
  • Anthony F Barbet
  • Kirk Deitsch
  • Basima Al-Khedery
  • Yu Ping Xiao
  • Agata K Zupańska
  • Germinal J Canto
  • Daniele M Swetnam
  • Paul B Drummond
  • Julio V Figueroa
  • Charles A Carson
  • Juan A Ramos
  • Edmundo E Rojas
  • J Antonio Alvarez
  • David Garcia-Tapia

Detail Information

Publications15

  1. ncbi request reprint Antigenic variation and cytoadhesion in Babesia bovis and Plasmodium falciparum: different logics achieve the same goal
    David R Allred
    Department of Pathobiology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32611 0880, USA
    Mol Biochem Parasitol 134:27-35. 2004
    ..In this review we contrast the molecular basis and 'genetic logic' for these critical behaviors in the two parasites, with emphasis on the biology of B. bovis...
  2. ncbi request reprint Babesiosis: persistence in the face of adversity
    David R Allred
    Dept of Pathobiology, College of Veterinary Medicine, University of Florida, Gainesville, FL 32611 0880, USA
    Trends Parasitol 19:51-5. 2003
    ..This update strives to illustrate the ramifications of these mechanisms and the interplay between them...
  3. ncbi request reprint Antigenic variation in babesiosis: is there more than one 'why'?
    D R Allred
    Department of Pathobiology, University of Florida, Gainesville, FL 32611 0880, USA
    Microbes Infect 3:481-91. 2001
    ..The molecular basis for antigenic variation in babesial parasites and its possible connection with cytoadherence and sequestration are discussed...
  4. ncbi request reprint The ves multigene family of B. bovis encodes components of rapid antigenic variation at the infected erythrocyte surface
    D R Allred
    Department of Pathobiology, University of Florida, Gainesville 32611, USA
    Mol Cell 5:153-62. 2000
    ..Variation appears to involve creation and modification or loss of a novel, transcribed copy of the gene...
  5. ncbi request reprint Antigenic variation in Babesia bovis: how similar is it to that in Plasmodium falciparum?
    D R Allred
    Department of Pathobiology, College of Veterinary Medicine, University of Florida, Gainesville 32611 0880, USA
    Ann Trop Med Parasitol 92:461-72. 1998
    ..falciparum. The significance of the similarities between B. bovis and P. falciparum, and the potential for contributions to be made to our understanding of malaria through the study of babesiosis are discussed...
  6. ncbi request reprint Immunochemical methods for identification of Babesia bovis antigens expressed on the erythrocyte surface
    D R Allred
    Department of Pathobiology, College of Veterinary Medicine, University of Florida, Gainesville, Florida, 32611 0880, USA
    Methods 13:177-89. 1997
    ..bovis-infected erythrocyte surface. These methods, which we present here, should be adaptable to a variety of intraerythrocytic parasite-host combinations...
  7. ncbi request reprint Dynamics of anemia progression and recovery in Babesia bigemina infection is unrelated to initiating parasite burden
    David R Allred
    University of Florida, Department of Infectious Diseases and Pathology, P O Box 110880, Gainesville, FL 32611 0880, USA
    Vet Parasitol 146:170-4. 2007
    ..bigemina immunization-and-challenge experiments. However, lengthening of the time to reduction in hematocrit may be a useful indicator of overt suppression of the challenge inoculum...
  8. ncbi request reprint Molecular technology and antigenic variation among intraerythrocytic hemoparasites: do we see reality?
    D R Allred
    Department of Pathobiology, University of Florida, P O Box 110880, Gainesville, FL 32611 0880, USA
    Vet Parasitol 101:261-74. 2001
    ..Some examples of this phenomenon are discussed in the context of a small selection of intraerythrocytic parasites...
  9. ncbi request reprint Antigenic variation in Babesia bovis occurs through segmental gene conversion of the ves multigene family, within a bidirectional locus of active transcription
    Basima Al-Khedery
    Department of Pathobiology, University of Florida, Gainesville, 32611, USA
    Mol Microbiol 59:402-14. 2006
    ..These results also suggest the possibility of epigenetic regulation through in situ switching among gene loci, further expanding the potential repertoire of variant proteins...
  10. ncbi request reprint Antigenic variation as an exploitable weakness of babesial parasites
    David R Allred
    Department of Pathobiology, University of Florida, Gainesville, FL 32611 0880, USA
    Vet Parasitol 138:50-60. 2006
    ..In this article, aspects of antigenic variation and cytoadhesion in bovine babesiosis are explored, with a discussion of opportunities for prophylactic or therapeutic intervention in these intertwined processes...
  11. pmc varDB: common ground for a shifting landscape
    David R Allred
    Department of Infectious Diseases and Pathology, University of Florida, Gainesville, FL 32611, USA
    Trends Parasitol 25:249-52. 2009
    ..A critique of this database and how it could serve the scientific community is provided here...
  12. pmc Universal primers suitable to assess population dynamics reveal apparent mutually exclusive transcription of the Babesia bovis ves1alpha gene
    Agata K Zupańska
    Department of Infectious Diseases and Pathology, University of Florida, Gainesville, FL 32611 0880, USA
    Mol Biochem Parasitol 166:47-53. 2009
    ..These characteristics of the primers will facilitate the application of polymerase chain reaction-based methodologies to the study of B. bovis population and antigenic switching dynamics...
  13. pmc The Babesia bovis VESA1 virulence factor subunit 1b is encoded by the 1beta branch of the ves multigene family
    Yu Ping Xiao
    University of Florida, Department of Infectious Diseases and Pathology, Gainesville, FL, USA
    Mol Biochem Parasitol 171:81-8. 2010
    ..These results provide essential information facilitating further investigation into this parasite virulence factor...
  14. pmc The msp1 beta multigene family of Anaplasma marginale: nucleotide sequence analysis of an expressed copy
    A F Barbet
    Department of Infectious Diseases, College of Veterinary Medicine, University of Florida, Gainesville 32611 0633
    Infect Immun 59:971-6. 1991
    ..The availability of the sequence will allow use of the polymerase chain reaction in diagnostic assays and the preparation and testing of different vaccine constructs in cattle...
  15. ncbi request reprint Evaluation of cattle inoculated with Babesia bovis clones adhesive in vitro to bovine brain endothelial cells
    Germinal J Canto
    CENID Fisiología Animal, INIFAP, Ajuchitlan, Qro, 76280 Mexico
    Ann N Y Acad Sci 1081:397-404. 2006
    ..While the four parasite subpopulations were pathogenic, significant differences were not noted among them, despite that the subpopulations considered to be virulent caused the greatest reduction in PCV per individual...