J D Bangs

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. pmc Expression of bloodstream variant surface glycoproteins in procyclic stage Trypanosoma brucei: role of GPI anchors in secretion
    J D Bangs
    Department of Medical Microbiology and Immunology, University of Wisconsin Madison Medical School, 53706, USA
    EMBO J 16:4285-94. 1997
  2. ncbi request reprint Surface coats and secretory trafficking in African trypanosomes
    J D Bangs
    Department of Medical Microbiology, University of Wisconsin Madison, 1300 University Avenue, Madison, WI 53706, USA
    Curr Opin Microbiol 1:448-54. 1998
  3. ncbi request reprint A cell-free assay for glycosylphosphatidylinositol anchoring in African trypanosomes. Demonstration of a transamidation reaction mechanism
    D K Sharma
    Department of Biochemistry, University of Wisconsin, Madison, Wisconsin, USA
    J Biol Chem 274:16479-86. 1999
  4. ncbi request reprint In vitro cytocidal effects on Trypanosoma brucei and inhibition of Leishmania major GP63 by peptidomimetic metalloprotease inhibitors
    J D Bangs
    Department of Medical Microbiology and Immunology, University of Wisconsin Madison, 1300 University Avenue, 53706, Madison, WI, USA
    Mol Biochem Parasitol 114:111-7. 2001
  5. ncbi request reprint Molecular cloning and biochemical characterization of a VCP homolog in African trypanosomes
    J L Roggy
    Department of Medical Microbiology and Immunology, University of Wisconsin Madison Medical School, 53706, USA
    Mol Biochem Parasitol 98:1-15. 1999
  6. pmc Soluble GPI8 restores glycosylphosphatidylinositol anchoring in a trypanosome cell-free system depleted of lumenal endoplasmic reticulum proteins
    D K Sharma
    Department of Biochemistry, University of Wisconsin Madison, 433 Babcock Drive, Madison, WI 53706, USA
    Biochem J 351:717-22. 2000
  7. ncbi request reprint Functional analysis of the trypanosomal AAA protein TbVCP with trans-dominant ATP hydrolysis mutants
    J R Lamb
    Department of Medical Microbiology and Immunology, University of Wisconsin-Madison Medical School, Madison, Wisconsin 53706, USA
    J Biol Chem 276:21512-20. 2001

Collaborators

Detail Information

Publications7

  1. pmc Expression of bloodstream variant surface glycoproteins in procyclic stage Trypanosoma brucei: role of GPI anchors in secretion
    J D Bangs
    Department of Medical Microbiology and Immunology, University of Wisconsin Madison Medical School, 53706, USA
    EMBO J 16:4285-94. 1997
    ..This unexpected result suggests that GPI processing may be influenced by adjacent peptide sequence or conformation...
  2. ncbi request reprint Surface coats and secretory trafficking in African trypanosomes
    J D Bangs
    Department of Medical Microbiology, University of Wisconsin Madison, 1300 University Avenue, Madison, WI 53706, USA
    Curr Opin Microbiol 1:448-54. 1998
    ..A growing list of novel secretory cargo molecules, as well as advances in the characterization of trypanosomal secretory machinery, provide a unique model system for the study of eukaryotic secretory processes...
  3. ncbi request reprint A cell-free assay for glycosylphosphatidylinositol anchoring in African trypanosomes. Demonstration of a transamidation reaction mechanism
    D K Sharma
    Department of Biochemistry, University of Wisconsin, Madison, Wisconsin, USA
    J Biol Chem 274:16479-86. 1999
    ..The reaction could be inhibited with sulfhydryl alkylating reagents, suggesting that the transamidase enzyme contains a functionally important sulfhydryl residue...
  4. ncbi request reprint In vitro cytocidal effects on Trypanosoma brucei and inhibition of Leishmania major GP63 by peptidomimetic metalloprotease inhibitors
    J D Bangs
    Department of Medical Microbiology and Immunology, University of Wisconsin Madison, 1300 University Avenue, 53706, Madison, WI, USA
    Mol Biochem Parasitol 114:111-7. 2001
    ..Biol. Chem. 1997;272:26742]. Development of higher affinity metalloprotease inhibitors may provide a novel avenue for treatment of parasitic diseases...
  5. ncbi request reprint Molecular cloning and biochemical characterization of a VCP homolog in African trypanosomes
    J L Roggy
    Department of Medical Microbiology and Immunology, University of Wisconsin Madison Medical School, 53706, USA
    Mol Biochem Parasitol 98:1-15. 1999
    ..Also like other VCP homologs, TbVCP contains an NEM-inhibitable ATPase activity. This is the first characterization of an AAA (ATPases Associated with a variety of cellular Activities) family member in African trypanosomes...
  6. pmc Soluble GPI8 restores glycosylphosphatidylinositol anchoring in a trypanosome cell-free system depleted of lumenal endoplasmic reticulum proteins
    D K Sharma
    Department of Biochemistry, University of Wisconsin Madison, 433 Babcock Drive, Madison, WI 53706, USA
    Biochem J 351:717-22. 2000
    ....
  7. ncbi request reprint Functional analysis of the trypanosomal AAA protein TbVCP with trans-dominant ATP hydrolysis mutants
    J R Lamb
    Department of Medical Microbiology and Immunology, University of Wisconsin-Madison Medical School, Madison, Wisconsin 53706, USA
    J Biol Chem 276:21512-20. 2001
    ..protein interactions essential to function have been maintained over great phylogenetic distances...