Rama Kamesh Bikkavilli

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. pmc Dishevelled3 is a novel arginine methyl transferase substrate
    Rama Kamesh Bikkavilli
    Division of Pulmonary Sciences and Critical Care, School of Medicine, Anschutz Medical Campus, University of Colorado Health Sciences Center, Aurora, Colorado 80045, USA
    Sci Rep 2:805. 2012
  2. pmc Wnt3a-stimulated LRP6 phosphorylation is dependent upon arginine methylation of G3BP2
    Rama Kamesh Bikkavilli
    Department of Pharmacology, School of Medicine, Health Sciences Center, State University of New York at Stony Brook, Stony Brook, NY 11794 8651, USA
    J Cell Sci 125:2446-56. 2012
  3. pmc Arginine methylation of G3BP1 in response to Wnt3a regulates β-catenin mRNA
    Rama Kamesh Bikkavilli
    Department of Pharmacology, School of Medicine, Health Sciences Center, State University of New York at Stony Brook, Stony Brook, NY 11794 8651, USA
    J Cell Sci 124:2310-20. 2011
  4. doi request reprint p38 mitogen-activated protein kinase regulates canonical Wnt-beta-catenin signaling by inactivation of GSK3beta
    Rama Kamesh Bikkavilli
    Department of Pharmacology, Health Sciences Center, State University of New York at Stony Brook, Stony Brook, NY 11794 8651, USA
    J Cell Sci 121:3598-607. 2008
  5. pmc Dishevelled-KSRP complex regulates Wnt signaling through post-transcriptional stabilization of beta-catenin mRNA
    Rama Kamesh Bikkavilli
    Department of Pharmacology, Health Sciences Center, State University of New York at Stony Brook, Stony Brook, NY 11794 8651, USA
    J Cell Sci 123:1352-62. 2010
  6. pmc Non-small-cell lung cancer: molecular targeted therapy and personalized medicine - drug resistance, mechanisms, and strategies
    Marybeth Sechler
    Division of Pulmonary Sciences and Critical Care, University of Colorado, Aurora, CO, USA Program in Cancer Biology, University of Colorado, Aurora, CO, USA
    Pharmgenomics Pers Med 6:25-36. 2013
  7. pmc hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression
    Sreedevi Avasarala
    Division of Pulmonary and Critical Care Sciences, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA
    Biol Open 2:675-85. 2013
  8. doi request reprint G alpha o mediates WNT-JNK signaling through dishevelled 1 and 3, RhoA family members, and MEKK 1 and 4 in mammalian cells
    Rama Kamesh Bikkavilli
    Department of Pharmacology, Health Sciences Center, State University of New York at Stony Brook, Stony Brook, NY 11794 8651, USA
    J Cell Sci 121:234-45. 2008

Collaborators

  • Robert A Winn
  • Michael E Feigin
  • Sreedevi Avasarala
  • Marybeth Sechler
  • Michelle Van Scoyk
  • Christine Brzezinski
  • Richard E Davis
  • Michael G Edwards
  • Colin Weekes
  • John Arcaroli
  • Katherine Vandervest
  • Amber D Cizmic
  • Nicole Kelley
  • Jianbin Wang

Detail Information

Publications8

  1. pmc Dishevelled3 is a novel arginine methyl transferase substrate
    Rama Kamesh Bikkavilli
    Division of Pulmonary Sciences and Critical Care, School of Medicine, Anschutz Medical Campus, University of Colorado Health Sciences Center, Aurora, Colorado 80045, USA
    Sci Rep 2:805. 2012
    ..Thus arginine methylation is shown to be an important switch in regulation of Dishevelled function and Wnt signaling...
  2. pmc Wnt3a-stimulated LRP6 phosphorylation is dependent upon arginine methylation of G3BP2
    Rama Kamesh Bikkavilli
    Department of Pharmacology, School of Medicine, Health Sciences Center, State University of New York at Stony Brook, Stony Brook, NY 11794 8651, USA
    J Cell Sci 125:2446-56. 2012
    ..Arginine methylation of G3BP2 appears to be a Wnt3a-sensitive 'switch' regulating LRP6 phosphorylation and canonical Wnt-β-catenin signaling...
  3. pmc Arginine methylation of G3BP1 in response to Wnt3a regulates β-catenin mRNA
    Rama Kamesh Bikkavilli
    Department of Pharmacology, School of Medicine, Health Sciences Center, State University of New York at Stony Brook, Stony Brook, NY 11794 8651, USA
    J Cell Sci 124:2310-20. 2011
    ..Methylation of G3BP1 constitutes a molecular switch that regulates Ctnnb1 mRNA in response to Wnt3a. Thus, the protein arginine methylation that targets G3BP1 acts as a novel regulator of Ctnnb1 mRNA...
  4. doi request reprint p38 mitogen-activated protein kinase regulates canonical Wnt-beta-catenin signaling by inactivation of GSK3beta
    Rama Kamesh Bikkavilli
    Department of Pharmacology, Health Sciences Center, State University of New York at Stony Brook, Stony Brook, NY 11794 8651, USA
    J Cell Sci 121:3598-607. 2008
    ..We demonstrate the involvement of G-proteins and Dishevelleds in Wnt3a-induced p38 MAPK activation, highlighting a critical role for p38 MAPK in canonical Wnt-beta-catenin signaling...
  5. pmc Dishevelled-KSRP complex regulates Wnt signaling through post-transcriptional stabilization of beta-catenin mRNA
    Rama Kamesh Bikkavilli
    Department of Pharmacology, Health Sciences Center, State University of New York at Stony Brook, Stony Brook, NY 11794 8651, USA
    J Cell Sci 123:1352-62. 2010
    ..Thus, Dishevelled-KSRP complex operates in Wnt regulation of beta-catenin, functioning post-transcriptionally upon CTNNB1 mRNA stability...
  6. pmc Non-small-cell lung cancer: molecular targeted therapy and personalized medicine - drug resistance, mechanisms, and strategies
    Marybeth Sechler
    Division of Pulmonary Sciences and Critical Care, University of Colorado, Aurora, CO, USA Program in Cancer Biology, University of Colorado, Aurora, CO, USA
    Pharmgenomics Pers Med 6:25-36. 2013
    ..A better understanding of these drug-resistance mechanisms could potentially benefit from the development of a more robust personalized medicine approach for the treatment of lung cancer...
  7. pmc hsa-miR29b, a critical downstream target of non-canonical Wnt signaling, plays an anti-proliferative role in non-small cell lung cancer cells via targeting MDM2 expression
    Sreedevi Avasarala
    Division of Pulmonary and Critical Care Sciences, School of Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA
    Biol Open 2:675-85. 2013
    ....
  8. doi request reprint G alpha o mediates WNT-JNK signaling through dishevelled 1 and 3, RhoA family members, and MEKK 1 and 4 in mammalian cells
    Rama Kamesh Bikkavilli
    Department of Pharmacology, Health Sciences Center, State University of New York at Stony Brook, Stony Brook, NY 11794 8651, USA
    J Cell Sci 121:234-45. 2008
    ..These data reveal both common and unique signaling elements in WNT3a-sensitive pathways, highlighting crosstalk from WNT3a-JNK to WNT3a-beta-catenin signaling...