Research Topics

Liang Chen

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. Chen L. A global comparison between nuclear and cytosolic transcriptomes reveals differential compartmentalization of alternative transcript isoforms. Nucleic Acids Res. 2010;38:1086-97 pubmed publisher
    ..In contrast, nonsense-mediated decay is significantly more associated with the isoforms enriched in the nucleus than those enriched in the cytosol. ..
  2. Chen L. Characterization and comparison of human nuclear and cytosolic editomes. Proc Natl Acad Sci U S A. 2013;110:E2741-7 pubmed publisher
    ..This suggests that editing can mediate RNA memory on evolutionary time-scales to maintain ancestral genetic information. ..

Detail Information

Publications2

  1. Chen L. A global comparison between nuclear and cytosolic transcriptomes reveals differential compartmentalization of alternative transcript isoforms. Nucleic Acids Res. 2010;38:1086-97 pubmed publisher
    ..In contrast, nonsense-mediated decay is significantly more associated with the isoforms enriched in the nucleus than those enriched in the cytosol. ..
  2. Chen L. Characterization and comparison of human nuclear and cytosolic editomes. Proc Natl Acad Sci U S A. 2013;110:E2741-7 pubmed publisher
    ..This suggests that editing can mediate RNA memory on evolutionary time-scales to maintain ancestral genetic information. ..