Elizabeth A Grove

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. ncbi Embryonic signaling centers expressing BMP, WNT and FGF proteins interact to pattern the cerebral cortex
    Tomomi Shimogori
    Department of Neurobiology, Pharmacology and Physiology, Committees on Neurobiology and Developmental Biology, University of Chicago, 947 E 58th Street, MC0926, Chicago, IL 60637, USA
    Development 131:5639-47. 2004
  2. ncbi The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient mice
    E A Grove
    Department of Pharmacological and Physiological Sciences, University of Chicago, Chicago, IL, USA
    Development 125:2315-25. 1998
  3. ncbi Patterning events and specification signals in the developing hippocampus
    E A Grove
    Department of Neurobiology, Pharmacology and Physiology, University of Chicago, IL 60637, USA
    Cereb Cortex 9:551-61. 1999
  4. ncbi Generating the cerebral cortical area map
    Elizabeth A Grove
    Department of Neurobiology, Pharmacology, and Physiology, University of Chicago, 947 East 58th Street, Chicago, IL 60637, USA
    Annu Rev Neurosci 26:355-80. 2003
  5. ncbi Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes(J)
    S Tole
    Department of Neurobiology, University of Chicago, Chicago, Illinois, 60637, USA
    Dev Biol 217:254-65. 2000
  6. pmc The cortical hem regulates the size and patterning of neocortex
    Giuliana Caronia-Brown
    Department of Neurobiology, University of Chicago, Chicago, IL 60637, USA
    Development 141:2855-65. 2014
  7. pmc FGF8 acts as a classic diffusible morphogen to pattern the neocortex
    Reiko Toyoda
    Department of Neurobiology, University of Chicago, Chicago, IL 60637, USA
    Development 137:3439-48. 2010
  8. pmc The chemokine stromal cell-derived factor-1 regulates the migration of sensory neuron progenitors
    Abdelhak Belmadani
    Department of Molecular Pharmacology and Biological Chemistry, Northwestern University Medical School, Chicago, Illinois 60611, USA
    J Neurosci 25:3995-4003. 2005
  9. pmc Shh and Gli3 regulate formation of the telencephalic-diencephalic junction and suppress an isthmus-like signaling source in the forebrain
    Brian G Rash
    Department of Neurobiology and Committees on Neurobiology and Developmental Biology, The University of Chicago, IL 60637, USA
    Dev Biol 359:242-50. 2011
  10. pmc Bone morphogenetic protein signaling in the developing telencephalon controls formation of the hippocampal dentate gyrus and modifies fear-related behavior
    Giuliana Caronia
    Department of Neurobiology, University of Chicago, Chicago, Illinois 60637, USA
    J Neurosci 30:6291-301. 2010

Collaborators

Detail Information

Publications32

  1. ncbi Embryonic signaling centers expressing BMP, WNT and FGF proteins interact to pattern the cerebral cortex
    Tomomi Shimogori
    Department of Neurobiology, Pharmacology and Physiology, Committees on Neurobiology and Developmental Biology, University of Chicago, 947 E 58th Street, MC0926, Chicago, IL 60637, USA
    Development 131:5639-47. 2004
    ..Our findings point to a cross-regulation of BMP, FGF, and WNT signaling in the early telencephalon, integrated by EMX2, and required for normal cortical development...
  2. ncbi The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient mice
    E A Grove
    Department of Pharmacological and Physiological Sciences, University of Chicago, Chicago, IL, USA
    Development 125:2315-25. 1998
    ....
  3. ncbi Patterning events and specification signals in the developing hippocampus
    E A Grove
    Department of Neurobiology, Pharmacology and Physiology, University of Chicago, IL 60637, USA
    Cereb Cortex 9:551-61. 1999
    ..Observations of mouse mutants indicate that the cortical hem, an embryonic structure close to one pole of the hippocampus, is a source of such regulatory signals...
  4. ncbi Generating the cerebral cortical area map
    Elizabeth A Grove
    Department of Neurobiology, Pharmacology, and Physiology, University of Chicago, 947 East 58th Street, Chicago, IL 60637, USA
    Annu Rev Neurosci 26:355-80. 2003
    ..Finally, embryonic structures interact to pattern one another. We review data suggesting that the thalamus and cortex are patterned independently then interact to generate the final cortical area map...
  5. ncbi Dorsoventral patterning of the telencephalon is disrupted in the mouse mutant extra-toes(J)
    S Tole
    Department of Neurobiology, University of Chicago, Chicago, Illinois, 60637, USA
    Dev Biol 217:254-65. 2000
    ..Our findings suggest that in dorsal telencephalon Gli3 is needed to repress ventral telencephalic identity...
  6. pmc The cortical hem regulates the size and patterning of neocortex
    Giuliana Caronia-Brown
    Department of Neurobiology, University of Chicago, Chicago, IL 60637, USA
    Development 141:2855-65. 2014
    ..Our findings reveal a much broader role for the hem in cortical development than previously recognized, and emphasize that two major signaling centers interact antagonistically to pattern cerebral cortex. ..
  7. pmc FGF8 acts as a classic diffusible morphogen to pattern the neocortex
    Reiko Toyoda
    Department of Neurobiology, University of Chicago, Chicago, IL 60637, USA
    Development 137:3439-48. 2010
    ..These observations support FGF8 as a classic diffusible morphogen in neocortex, thereby guiding future studies of neocortical pattern formation...
  8. pmc The chemokine stromal cell-derived factor-1 regulates the migration of sensory neuron progenitors
    Abdelhak Belmadani
    Department of Molecular Pharmacology and Biological Chemistry, Northwestern University Medical School, Chicago, Illinois 60611, USA
    J Neurosci 25:3995-4003. 2005
    ..Our findings indicate an important role for SDF-1/CXCR4 signaling in directing the migration of sensory neuron progenitors to the DRG and potentially in other aspects of development once the DRGs have coalesced...
  9. pmc Shh and Gli3 regulate formation of the telencephalic-diencephalic junction and suppress an isthmus-like signaling source in the forebrain
    Brian G Rash
    Department of Neurobiology and Committees on Neurobiology and Developmental Biology, The University of Chicago, IL 60637, USA
    Dev Biol 359:242-50. 2011
    ..That optional signaling centers are actively repressed in normal development is a striking new insight into the processes of vertebrate brain development...
  10. pmc Bone morphogenetic protein signaling in the developing telencephalon controls formation of the hippocampal dentate gyrus and modifies fear-related behavior
    Giuliana Caronia
    Department of Neurobiology, University of Chicago, Chicago, Illinois 60637, USA
    J Neurosci 30:6291-301. 2010
    ....
  11. ncbi Identification of a Pax6-dependent epidermal growth factor family signaling source at the lateral edge of the embryonic cerebral cortex
    Stavroula Assimacopoulos
    Department of Neurobiology, Pharmacology, and Physiology, The University of Chicago, Chicago, Illinois 60637, USA
    J Neurosci 23:6399-403. 2003
    ..We find that the antihem is lost in mice homozygous for the Small eye (Pax6) mutation and suggest the loss of EGF signaling at least partially explains defects in cortical patterning and cell migration in Small eye mice...
  12. ncbi Emx2 is required for growth of the hippocampus but not for hippocampal field specification
    S Tole
    Department of Neurobiology, Pharmacology, and Physiology, University of Chicago, Chicago, Illinois 60637, USA
    J Neurosci 20:2618-25. 2000
    ..Thus, Emx2 is required for normal growth and maturation of the hippocampus but not for the specification of cells to particular hippocampal field identities...
  13. pmc Fibroblast growth factor 8 organizes the neocortical area map and regulates sensory map topography
    Stavroula Assimacopoulos
    Department of Neurobiology, University of Chicago, Chicago, Illinois 60637, USA
    J Neurosci 32:7191-201. 2012
    ..Our findings implicate FGF8 as an organizer signal, and its source in the rostromedial telencephalon as an organizer of the neocortical area map...
  14. pmc Timing of cortical interneuron migration is influenced by the cortical hem
    Giuliana Caronia-Brown
    Department of Neurobiology, University of Chicago, Chicago, IL 60637, USA
    Cereb Cortex 21:748-55. 2011
    ....
  15. ncbi Massive loss of Cajal-Retzius cells does not disrupt neocortical layer order
    Michio Yoshida
    Department of Neurobiology, Pharmacology and Physiology, University of Chicago, IL 60637, USA
    Development 133:537-45. 2006
    ..Our findings indicate, however, that the sheet of reelin-rich CR cells that covers the neocortical primordium is not required to direct layer order...
  16. ncbi Presenilin 1 in migration and morphogenesis in the central nervous system
    Angeliki Louvi
    Department of Neurobiology, Pharmacology and Physiology, University of Chicago, 947 E 58th Street, Chicago, IL 60637, USA
    Development 131:3093-105. 2004
    ..Our results demonstrate that presenilin 1 plays a much more important role in brain development than has been assumed, consistent with a pleiotropic involvement of this molecule in cellular signaling...
  17. ncbi Early specification and autonomous development of cortical fields in the mouse hippocampus
    S Tole
    Department of Pharmacological and Physiological Sciences, Pritzker School of Medicine, University of Chicago, IL 60637, USA
    Development 124:4959-70. 1997
    ..We suggest that the sources of signals that specify hippocampal field identity lie close to the hippocampal poles, and that the signals operate first on cells at the poles, then move inwards...
  18. doi Neuroscience. Organizing the source of memory
    Elizabeth A Grove
    Department of Neurobiology, University of Chicago, Chicago, IL 60637, USA
    Science 319:288-9. 2008
  19. ncbi Fibroblast growth factor 8 regulates neocortical guidance of area-specific thalamic innervation
    Tomomi Shimogori
    Department of Neurobiology, Pharmacology, and Physiology, University of Chicago, Chicago, Illinois 60637, USA
    J Neurosci 25:6550-60. 2005
    ..Our findings demonstrate that thalamocortical axons are directed by sequential, positional cues within the cortex and implicate FGF8 as an indirect regulator of thalamocortical innervation...
  20. ncbi Local axon guidance in cerebral cortex and thalamus: are we there yet?
    Elizabeth A Grove
    Department of Neurobiology, Pharmacology and Physiology, University of Chicago, Chicago, Illinois 60637
    Neuron 48:522-4. 2005
    ..Although EphA/ephrin-A signaling organizes sensory maps within areas, and thalamocortical axons in the internal capsule, both papers argue that each developmental event is dissociable from the others...
  21. ncbi Emx2 patterns the neocortex by regulating FGF positional signaling
    Tomomi Fukuchi-Shimogori
    Department of Neurobiology, Pharmacology and Physiology, University of Chicago, 947 East 58th Street, MC0926, Chicago, Illinois 60637, USA
    Nat Neurosci 6:825-31. 2003
    ..These findings begin to clarify the signaling network that patterns the neocortical area map...
  22. ncbi Patterning the dorsal telencephalon: a role for sonic hedgehog?
    Brian G Rash
    Department of Neurobiology, University of Chicago, Chicago, Illinois 60637, USA
    J Neurosci 27:11595-603. 2007
    ..Our findings point away from Shh involvement in dorsal telencephalic patterning and encourage additional exploration of Fgf signaling and Gli3 repression in corticogenesis...
  23. ncbi Patterning the mammalian cerebral cortex
    C W Ragsdale
    Department of Neurobiology, Pharmacology and Physiology, University of Chicago, 947 East 58th Street, Chicago, IL 60637, USA
    Curr Opin Neurobiol 11:50-8. 2001
    ..However, new evidence also confirms the special nature of the cerebral cortex, in that cues from developing connections appear to modify and refine the final area map...
  24. ncbi Area and layer patterning in the developing cerebral cortex
    Brian G Rash
    Department of Neurobiology, Pharmacology and Physiology, The University of Chicago, Chicago IL, 60637, USA
    Curr Opin Neurobiol 16:25-34. 2006
    ..New observations clarify the molecular and cellular mechanisms that generate each pattern, and stress the links between layer and area formation...
  25. pmc Ancient deuterostome origins of vertebrate brain signalling centres
    Ariel M Pani
    Committee on Evolutionary Biology, The University of Chicago, 1025 East 57th Street, Chicago, Illinois 60637, USA
    Nature 483:289-94. 2012
    ....
  26. doi Turning neurons into a nervous system
    Elizabeth A Grove
    Department of Neurobiology, University of Chicago, Chicago, IL 60637, USA
    Development 135:2203-6. 2008
    ..Researchers from Japan, Europe and the USA gathered at this meeting to share insights into neural development and to admire the opening of the cherry blossom season...
  27. pmc Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor
    Meiling Lu
    Department of Molecular Pharmacology and Biological Chemistry, Northwestern University, Chicago, IL 60611, USA
    Proc Natl Acad Sci U S A 99:7090-5. 2002
    ..Finally, the DG is unusual as a site of adult neurogenesis. We find that both CXCR4 and SDF-1 are expressed in the adult DG, suggesting an ongoing role in DG morphogenesis...
  28. ncbi Detailed field pattern is intrinsic to the embryonic mouse hippocampus early in neurogenesis
    S Tole
    Department of Neurobiology, Pharmacology and Physiology, Committees on Developmental Biology and Neurobiology, University of Chicago, Chicago, Illinois 60637, USA
    J Neurosci 21:1580-9. 2001
    ..5. By E12.5, hippocampal field patterning appears to be well established and resistant to the manipulation of several potential intrinsic cues...
  29. ncbi Neocortex patterning by the secreted signaling molecule FGF8
    T Fukuchi-Shimogori
    Department of Neurobiology, Pharmacology and Physiology, University of Chicago, Chicago, IL 60637, USA
    Science 294:1071-4. 2001
    ..These findings support a role for FGF signaling in specifying positional identity in the neocortex...
  30. ncbi Conserved expression of Hoxa1 in neurons at the ventral forebrain/midbrain boundary of vertebrates
    J M McClintock
    Committee on Developmental Biology, Department of Organismal Biology and Anatomy, University of Chicago, 1027 E 57th St, Chicago, IL 60637, USA
    Dev Genes Evol 213:399-406. 2003
    ....
  31. ncbi The derivatives of the Wnt3a lineage in the central nervous system
    Angeliki Louvi
    Department of Neurosurgery, Program on Neurogenetics, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Comp Neurol 504:550-69. 2007
    ....
  32. ncbi Loss of Emx2 function leads to ectopic expression of Wnt1 in the developing telencephalon and cortical dysplasia
    Keith L Ligon
    Department of Pediatric Oncology, Dana Farber Cancer Institute and Harvard Medical School, 44 Binney Street, Boston, MA 0215, USA
    Development 130:2275-87. 2003
    ..They further suggest that EMX2-Wnt1 interactions are essential for normal development of preplate derivatives in the mammalian cerebral cortex...