M W Jackwood

Summary

Affiliation: University of Georgia
Country: USA

Publications

  1. ncbi request reprint Review of infectious bronchitis virus around the world
    Mark W Jackwood
    Department of Population Health, Poultry Diagnostic and Research Center, College of Veterinary Medicine, 953 College Station Road, University of Georgia, Athens, GA 30602, USA
    Avian Dis 56:634-41. 2012
  2. doi request reprint Simultaneous detection of five major serotypes of Avian coronavirus by a multiplex microsphere-based assay
    Ha Jung Roh
    Department of Population Health, Poultry Diagnostic and Research Center, University of Georgia, Athens, GA 30602, USA
    J Vet Diagn Invest 25:458-66. 2013
  3. doi request reprint The long view: 40 years of infectious bronchitis research
    Jane K A Cook
    Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, 30602, USA
    Avian Pathol 41:239-50. 2012
  4. doi request reprint Molecular evolution and emergence of avian gammacoronaviruses
    Mark W Jackwood
    Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, United States
    Infect Genet Evol 12:1305-11. 2012
  5. doi request reprint Rapid heat-treatment attenuation of infectious bronchitis virus
    Mark W Jackwood
    Department of Population Health, Poultry Diagnostic and Research Center, 953 College Station Road, University of Georgia, Athens, GA 30602, USA
    Avian Pathol 39:227-33. 2010
  6. ncbi request reprint Biologic characterization of chicken-derived H6N2 low pathogenic avian influenza viruses in chickens and ducks
    Mark W Jackwood
    Department of Population Health, College of Veterinary Medicine, University of Georgia, 953 College Station Road, Athens, GA 30602, USA
    Avian Dis 54:120-5. 2010
  7. ncbi request reprint Efficacy of a replikin peptide vaccine against low-pathogenicity avian influenza H5 virus
    Mark W Jackwood
    Department of Population Health, College of Veterinary Medicine, University of Georgia, 953 College Station Road, Athens, GA 30602, USA
    Avian Dis 53:613-7. 2009
  8. doi request reprint Emergence of a group 3 coronavirus through recombination
    Mark W Jackwood
    Department of Population Health, College of Veterinary Medicine, 953 College Station Road, University of Georgia, Athens, GA 30602, USA
    Virology 398:98-108. 2010
  9. doi request reprint Avian coronavirus infectious bronchitis virus susceptibility to botanical oleoresins and essential oils in vitro and in vivo
    M W Jackwood
    Department of Population Health, Poultry Diagnostic and Research Center, University of Georgia, 953 College Station Road, Athens, GA 30602, United States
    Virus Res 149:86-94. 2010
  10. ncbi request reprint Infectious bronchitis virus field vaccination coverage and persistence of Arkansas-type viruses in commercial broilers
    Mark W Jackwood
    Department of Population Health, Poultry Diagnostic and Research Center, 953 College Station Road, University of Georgia, Athens, GA 30602, USA
    Avian Dis 53:175-83. 2009

Collaborators

Detail Information

Publications45

  1. ncbi request reprint Review of infectious bronchitis virus around the world
    Mark W Jackwood
    Department of Population Health, Poultry Diagnostic and Research Center, College of Veterinary Medicine, 953 College Station Road, University of Georgia, Athens, GA 30602, USA
    Avian Dis 56:634-41. 2012
    ..The information on IBV types presented herein is from published manuscripts, submissions to GenBank, our own unpublished data, and personal communications with scientists and diagnosticians working with IBV worldwide...
  2. doi request reprint Simultaneous detection of five major serotypes of Avian coronavirus by a multiplex microsphere-based assay
    Ha Jung Roh
    Department of Population Health, Poultry Diagnostic and Research Center, University of Georgia, Athens, GA 30602, USA
    J Vet Diagn Invest 25:458-66. 2013
    ..The results demonstrate the utility of the microsphere-based assay as a rapid and accurate diagnostic tool with the potential for high throughput diagnosis. ..
  3. doi request reprint The long view: 40 years of infectious bronchitis research
    Jane K A Cook
    Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, 30602, USA
    Avian Pathol 41:239-50. 2012
    ..It also discusses the impact of developments in the field of molecular biology and highlights possible areas for future work...
  4. doi request reprint Molecular evolution and emergence of avian gammacoronaviruses
    Mark W Jackwood
    Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, United States
    Infect Genet Evol 12:1305-11. 2012
    ....
  5. doi request reprint Rapid heat-treatment attenuation of infectious bronchitis virus
    Mark W Jackwood
    Department of Population Health, Poultry Diagnostic and Research Center, 953 College Station Road, University of Georgia, Athens, GA 30602, USA
    Avian Pathol 39:227-33. 2010
    ..The attenuation process took 10 weeks to complete, which is a substantially shorter time than required to attenuate infectious bronchitis virus by serial passage in embryonated eggs without heat treatment (38 weeks or more)...
  6. ncbi request reprint Biologic characterization of chicken-derived H6N2 low pathogenic avian influenza viruses in chickens and ducks
    Mark W Jackwood
    Department of Population Health, College of Veterinary Medicine, University of Georgia, 953 College Station Road, Athens, GA 30602, USA
    Avian Dis 54:120-5. 2010
    ..However, the viruses isolated in 2004 did not appear to replicate or cause more disease than earlier virus isolates...
  7. ncbi request reprint Efficacy of a replikin peptide vaccine against low-pathogenicity avian influenza H5 virus
    Mark W Jackwood
    Department of Population Health, College of Veterinary Medicine, University of Georgia, 953 College Station Road, Athens, GA 30602, USA
    Avian Dis 53:613-7. 2009
    ..The study is also important because it shows that the vaccine can be effectively mass-delivered to the upper respiratory tract...
  8. doi request reprint Emergence of a group 3 coronavirus through recombination
    Mark W Jackwood
    Department of Population Health, College of Veterinary Medicine, 953 College Station Road, University of Georgia, Athens, GA 30602, USA
    Virology 398:98-108. 2010
    ....
  9. doi request reprint Avian coronavirus infectious bronchitis virus susceptibility to botanical oleoresins and essential oils in vitro and in vivo
    M W Jackwood
    Department of Population Health, Poultry Diagnostic and Research Center, University of Georgia, 953 College Station Road, Athens, GA 30602, United States
    Virus Res 149:86-94. 2010
    ..To our knowledge, this is the first report on the in vivo use of a virucidal mixture of compounds effective against the coronavirus IBV...
  10. ncbi request reprint Infectious bronchitis virus field vaccination coverage and persistence of Arkansas-type viruses in commercial broilers
    Mark W Jackwood
    Department of Population Health, Poultry Diagnostic and Research Center, 953 College Station Road, University of Georgia, Athens, GA 30602, USA
    Avian Dis 53:175-83. 2009
    ..In addition, Arkansas vaccine viruses are clearly persisting in commercial broilers, which may be because of incomplete protection observed for that IBV type...
  11. ncbi request reprint Molecular and serologic characterization, pathogenicity, and protection studies with infectious bronchitis virus field isolates from California
    Mark W Jackwood
    Department of Population Health, Poultry Diagnostic and Research Center, 953 College Station Road, University of Georgia, Athens, GA 30602, USA
    Avian Dis 51:527-33. 2007
    ....
  12. ncbi request reprint Identification and analysis of the Georgia 98 serotype, a new serotype of infectious bronchitis virus
    C W Lee
    Department of Avian Medicine, College of Veterinary Medicine, The University of Georgia, Athens 30602, USA
    Avian Dis 45:164-72. 2001
    ..Consequently, we designated this group as a new serotype, Georgia 98. We developed a restriction fragment length polymorphism analysis that can differentiate this new serotype from all other serotypes of IBV...
  13. doi request reprint Changes in nonstructural protein 3 are associated with attenuation in avian coronavirus infectious bronchitis virus
    J E Phillips
    Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
    Virus Genes 44:63-74. 2012
    ....
  14. doi request reprint Avian coronavirus infectious bronchitis attenuated live vaccines undergo selection of subpopulations and mutations following vaccination
    Enid T McKinley
    College of Veterinary Medicine, Department of Population Health, Poultry Diagnostic and Research Center, 953 College Station Road, University of Georgia, Athens, GA 30602, USA
    Vaccine 26:1274-84. 2008
    ..This information is also valuable for the development of safer modified live coronavirus vaccines...
  15. ncbi request reprint Detection of Massachusetts and Arkansas serotypes of infectious bronchitis virus in broilers
    I R Alvarado
    Department of Population Health, University of Georgia, Athens 30605, USA
    Avian Dis 50:292-7. 2006
    ..In general, the Mass strain was more frequently recovered from the tracheal and cecal tonsil tissues at earlier stages of infection and the Ark strain was recovered at later stages of infection...
  16. ncbi request reprint Molecular characterization of infectious bronchitis virus isolates foreign to the United States and comparison with United States isolates
    S A Callison
    Department of Avian Medicine, Poultry Diagnostic and Research Center, College of Veterinary Medicine, University of Georgia, Athens 30602-4875, USA
    Avian Dis 45:492-9. 2001
    ..With the RFLP patterns and the deduced S1 amino acid sequence data as a reference, none of the IBV isolates foreign to the United States have been detected in the United States...
  17. ncbi request reprint Spike gene analysis of the DE072 strain of infectious bronchitis virus: origin and evolution
    C W Lee
    Department of Avian Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602-4875, USA
    Virus Genes 22:85-91. 2001
    ..Furthermore, entire spike gene analysis indicates that the DE072 strain has undergone recombination event as well as extensive antigenic variation...
  18. ncbi request reprint Attenuation, safety, and efficacy of an infectious bronchitis virus GA98 serotype vaccine
    Mark W Jackwood
    Department of Avian Medicine, College of Veterinary Medicine, The University of Georgia, Athens, GA 30602, USA
    Avian Dis 47:627-32. 2003
    ..5) 50% embryo infectious dose/bird protected against the homologous GA98 challenge as well as provided good protection against the DE072-type virus. In addition, the vaccine was shown to be adequately attenuated and safe at a 10x dosage...
  19. ncbi request reprint Spike glycoprotein cleavage recognition site analysis of infectious bronchitis virus
    M W Jackwood
    Department of Avian Medicine, Poultry Diagnostic and Research Center, College of Veterinary Medicine, University of Georgia, Athens 30602-4875, USA
    Avian Dis 45:366-72. 2001
    ....
  20. ncbi request reprint Molecular characterization of avian infectious bronchitis virus strains isolated in Colombia during 2003
    I R Alvarado
    Department of Avian Medicine, University of Georgia, Athens, GA 30602, USA
    Avian Dis 49:494-9. 2005
    ..Four unique genotype clusters containing isolates with indigenous genotypes were observed. One isolate was found to be the Connecticut genotype and three isolates were found to be the Massachusetts genotype...
  21. ncbi request reprint Antimicrobial activity of chicken and turkey heterophil peptides CHP1, CHP2, THP1, and THP3
    E W Evans
    Department of Veterinary Pathology, University of Georgia, Athens, USA
    Vet Microbiol 47:295-303. 1995
    ..Under our experimental conditions, none of the peptides neutralized Infectious Bronchitis Virus, an enveloped coronavirus of chickens...
  22. ncbi request reprint Polymerase chain reaction and a biotin-labeled DNA probe for detection of infectious bronchitis virus in chickens
    H M Kwon
    Department of Avian Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602
    Avian Dis 37:149-56. 1993
    ..The field samples were passed four to six times in embryonating eggs, and 10 of 17 samples were positive using PCR and the biotin-labeled probe...
  23. ncbi request reprint Origin and evolution of Georgia 98 (GA98), a new serotype of avian infectious bronchitis virus
    C W Lee
    Department of Avian Medicine, College of Veterinary Medicine, The University of Georgia, 953 College Station Road, Athens, GA 30602, USA
    Virus Res 80:33-9. 2001
    ..Together with virus neutralization data, it appears that GA98 arose from immune selection caused by DE072 vaccine use. Reasons for this conclusion are discussed...
  24. ncbi request reprint Detection of infectious bronchitis virus by real-time reverse transcriptase-polymerase chain reaction and identification of a quasispecies in the Beaudette strain
    M W Jackwood
    Department of Avian Medicine, Poultry Diagnostic and Research Center, College of Veterinary Medicine, 953 College Station Road, University of Georgia, Athens, GA 30602, USA
    Avian Dis 47:718-24. 2003
    ....
  25. ncbi request reprint Typing of field isolates of infectious bronchitis virus based on the sequence of the hypervariable region in the S1 gene
    Chang Won Lee
    Department of Avian Medicine, College of Veterinary Medicine, The University of Georgia, Athens, GA 30602, USA
    J Vet Diagn Invest 15:344-8. 2003
    ..Furthermore, it was found that typing by phylogenetic analysis of that region correlates with virus neutralization results. Together with RT-PCR and RFLP, this method will serve as a fast typing method for IBV diagnosis...
  26. ncbi request reprint Development and evaluation of a real-time Taqman RT-PCR assay for the detection of infectious bronchitis virus from infected chickens
    Scott A Callison
    Department of Population Health, Poultry Diagnostic and Research Center, 953 College Station Road, University of Georgia, Athens, GA 30602, USA
    J Virol Methods 138:60-5. 2006
    ..The test was extremely sensitive and specific, and can be used to quantitate viral genomic RNA in clinical samples...
  27. ncbi request reprint Enteric viruses detected by molecular methods in commercial chicken and turkey flocks in the United States between 2005 and 2006
    Mary J Pantin-Jackwood
    Southeast Poultry Research Laboratory, USDA, Agricultural Research Service, Athens, GA 30605, USA
    Avian Dis 52:235-44. 2008
    ....
  28. ncbi request reprint Molecular epidemiology of avian leukosis virus subgroup J and evolutionary history of its 3' untranslated region
    G Zavala
    Poultry Diagnostic and Research Center, Department of Population Health, University of Georgia, Athens, GA 30602, USA
    Avian Dis 51:942-53. 2007
    ..Some of the mutations in the 3' UTR have resulted in the emergence of moderately distinct genetic lineages representing each primary breeding company from which ALV-J was isolated...
  29. ncbi request reprint Rapid differentiation of avian infectious bronchitis virus isolates by sample to residual ratio quantitation using real-time reverse transcriptase-polymerase chain reaction
    S A Callison
    Department of Avian Medicine, PDRC, College of Veterinary Medicine, The University of Georgia, 953 College Station Road, Athens, GA 30602, USA
    J Virol Methods 124:183-90. 2005
    ..The assay is rapid; six samples can be tested in approximately 4 h. In addition, the primer set amplifies all IBV RNAs tested to date and provides a built in control for detecting IBV whether it is typeable or not...
  30. ncbi request reprint Detection of in ovo-inoculated infectious bronchitis virus by immunohistochemistry and in situ hybridization with a riboprobe in epithelial cells of the lung and cloacal bursa
    D R Kapczynski
    Department of Avian Medicine, Poultry Diagnostic and Research Center, College of Veterinary Medicine, University of Georgia, Athens 30602, USA
    Avian Dis 46:679-85. 2002
    ..These results indicate that in situ hybridization can be useful in detection of IBV-infected chickens and in understanding the pathogenesis and virulence of IBV infection...
  31. ncbi request reprint Current and future recombinant viral vaccines for poultry
    M W Jackwood
    Department of Avian Medicine, College of Veterinary Medicine, University of Georgia, Athens 30602, USA
    Adv Vet Med 41:517-22. 1999
    ..A vaccine that is novel because it is a recombinant vaccine is not enough. Recombinant vaccines must be safer, or more efficacious, or less expensive to produce in order for them to gain a niche in the marketplace...
  32. ncbi request reprint Protection of chickens from infectious bronchitis by in ovo and intramuscular vaccination with a DNA vaccine expressing the S1 glycoprotein
    Darrell R Kapczynski
    University of Georgia, Poultry Diagnostic and Research Center, College of Veterinary Medicine, 953 College Station Road, Athens, GA 30602, USA
    Avian Dis 47:272-85. 2003
    ..These data indicate that DNA vaccination with the S1 gene either in ovo or intramuscularly can provide birds with some protection against clinical disease after homologous IBV challenge...
  33. ncbi request reprint Biologic characterization of H4, H6, and H9 type low pathogenicity avian influenza viruses from wild birds in chickens and turkeys
    Antonio C Morales
    Department of Population Health, College of Veterinary Medicine, University of Georgia, 953 College Station Road, Athens, GA 30602, USA
    Avian Dis 53:552-62. 2009
    ..Specifically, detection is difficult because these viruses did not cause overt clinical disease or mortality, but only induced mild microscopic lesions and exhibited poor seroconversion...
  34. ncbi request reprint Data from 11 years of molecular typing infectious bronchitis virus field isolates
    Mark W Jackwood
    Department of Avian Medicine, Poultry Diagnostic and Research Center, 953 College Station Road, University of Georgia, Athens, GA 30602, USA
    Avian Dis 49:614-8. 2005
    ..Our observations highlight the importance of constantly monitoring IBV as well as other coronaviruses like severe acute respiratory syndrome-coronavirus that have the ability to change and emerge to cause disease in a susceptible host...
  35. doi request reprint Comparative sequence analysis of full-length genome of FIPV at different tissue passage levels
    J E Phillips
    Department of Population Health, College of Veterinary Medicine, University of Georgia, 953 College Station Road, Athens, GA, 30605, USA
    Virus Genes 47:490-7. 2013
    ..Our data show that FIPV has a low mutation rate as it is passed in cell culture but has the capacity for change specifically in nsp 2, 3c, and 7b as it is passed in cell culture...
  36. ncbi request reprint Lack of interaction between avian leukosis virus subgroup J and fowl adenovirus (FAV) in FAV-antibody-positive chickens
    G Zavala
    Department of Avian Medicine, The University of Georgia, Athens, GA 30602, USA
    Avian Dis 46:979-84. 2002
    ..With such criteria for evaluating possible interactions, we found no significant differences in the dually infected birds in comparison with chickens that received a monovalent challenge with either FAV or ALV-J...
  37. ncbi request reprint Nephropathogenesis of chickens experimentally infected with various strains of infectious bronchitis virus
    Chang Won Lee
    Department of Avian Medicine, College of Veterinary Medicine, The University of Georgia, Athens 30602, USA
    J Vet Med Sci 66:835-40. 2004
    ..These results indicate that the pathological changes in kidneys from chickens infected with Gray and CV56b may not have resulted from the cytolytic action of the virus...
  38. pmc Phylogenetic relationships among highly virulent Newcastle disease virus isolates obtained from exotic birds and poultry from 1989 to 1996
    B S Seal
    Southeast Poultry Research Laboratory, USDA Agricultural Research Service, Athens, Georgia 30605, USA
    J Clin Microbiol 36:1141-5. 1998
    ..Recent virulent NDV isolates and those recovered during disease outbreaks since the 1970s are phylogenetically distinct from current vaccine viruses and standard challenge strains...
  39. ncbi request reprint Sequence analysis of Pasteurella multocida major outer membrane protein (OmpH) and application of synthetic peptides in vaccination of chickens against homologous strain challenge
    Y Luo
    Department of Avian Medicine, College of Veterinary Medicine, The University of Georgia, Athens 30602, USA
    Vaccine 17:821-31. 1999
    ..This is the first report that a synthetic peptide mimicking the conformational epitopes of a native protein provide practical protection in target animal against bacterial infection...
  40. ncbi request reprint Tissue distribution of avian infectious bronchitis virus following in ovo inoculation of chicken embryos examined by in situ hybridization with antisense digoxigenin-labeled universal riboprobe
    Chang Won Lee
    Department of Avian Medicine, College of Veterinary Medicine, The University of Georgia, Athens 30602, USA
    J Vet Diagn Invest 14:377-81. 2002
    ..In situ hybridization with this probe will be useful for understanding the tissue tropism and the pathogenesis of IBV in vivo...
  41. ncbi request reprint Molecular epidemiologic studies on North American H9 avian influenza virus isolates from waterfowl and shorebirds
    Mark W Jackwood
    Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
    Avian Dis 51:448-50. 2007
    ..Positive evolutionary selection (dNonsynonymous > dSynonymous) was observed for the HA gene among the North American waterfowl and shorebird H9N2 viruses, indicating that the H9N2-type viruses are changing in their natural hosts...
  42. ncbi request reprint In vitro analysis of a hammerhead ribozyme targeted to infectious bronchitis virus nucleocapsid mRNA
    Scott A Callison
    Department of Avian Medicine, Poultry and Diagnostic Research Center, College of Veterinary Medicine, 953 College Station Road, Athens, GA 30602, USA
    Avian Dis 49:159-63. 2005
    ..Although stability and delivery problems must be overcome, a hammerhead ribozyme targeted to the IBV nucleocapsid mRNA most likely has antiviral activity and may be an effective therapeutic/prophylactic reagent in the future...
  43. ncbi request reprint Characterization of beta-defensin prepropeptide mRNA from chicken and turkey bone marrow
    C W Brockus
    Department of Veterinary Pathology, College of Veterinary Medicine, University of Georgia, Athens 30602, USA
    Anim Genet 29:283-9. 1998
    ..These are the first prepropeptide beta-defensins from leukocyte granules to be completely characterized...
  44. ncbi request reprint Polymerase chain reaction for detection of avian leukosis virus subgroup J in feather pulp
    Guillermo Zavala
    Department of Avian Medicine, College of Veterinary Medicine, The University of Georgia, Athens, GA 30602, USA
    Avian Dis 46:971-8. 2002
    ....
  45. ncbi request reprint The relationship of severe acute respiratory syndrome coronavirus with avian and other coronaviruses
    Mark W Jackwood
    Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
    Avian Dis 50:315-20. 2006
    ..This is significant because SARS-CoV is likely still circulating in an animal reservoir (or reservoirs) and has the potential to quickly emerge and cause a new epidemic...