Besik I Kankia

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. pmc Optical absorption assay for strand-exchange reactions in unlabeled nucleic acids
    Besik I Kankia
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA
    Nucleic Acids Res 32:e154. 2004
  2. ncbi request reprint The HIV-1 central DNA flap region contains a "flapping" third strand
    Besik I Kankia
    Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, United States
    Biophys Chem 127:64-8. 2007
  3. ncbi request reprint Binding of Mg2+ to single-stranded polynucleotides: hydration and optical studies
    Besik I Kankia
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 1479 Gortner Avenue, St Paul, Minnesota, MN 55108, USA
    Biophys Chem 104:643-54. 2003
  4. pmc Mg2+-induced triplex formation of an equimolar mixture of poly(rA) and poly(rU)
    Besik I Kankia
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 1479 Gortner Avenue, St Paul, MN 55108, USA
    Nucleic Acids Res 31:5101-7. 2003
  5. ncbi request reprint Inner-sphere complexes of divalent cations with single-stranded poly(rA) and poly(rU)
    Besik I Kankia
    Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA
    Biopolymers 74:232-9. 2004
  6. pmc A real-time assay for monitoring nucleic acid cleavage by quadruplex formation
    Besik I Kankia
    Department of Chemistry, University of Minnesota, MN 55455, USA
    Nucleic Acids Res 34:e141. 2006
  7. pmc Unfolding of DNA quadruplexes induced by HIV-1 nucleocapsid protein
    Besik I Kankia
    Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, USA
    Nucleic Acids Res 33:4395-403. 2005
  8. doi request reprint HIV-integrase aptamer folds into a parallel quadruplex: a thermodynamic study
    Sean Kelley
    Department of Chemistry, The Ohio State University, Columbus, OH 43210, USA
    Biophys Chem 155:82-8. 2011
  9. doi request reprint Self-dissociative primers for nucleic acid amplification and detection based on DNA quadruplexes with intrinsic fluorescence
    Besik I Kankia
    Department of Chemistry, The Ohio State University, Columbus, OH 43210, USA
    Anal Biochem 409:59-65. 2011
  10. ncbi request reprint DNA oligonucleotide duplexes containing intramolecular platinated cross-links: energetics, hydration, sequence, and ionic effects
    Besik I Kankia
    Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, 68198, USA
    Biopolymers 65:218-27. 2002

Collaborators

Detail Information

Publications11

  1. pmc Optical absorption assay for strand-exchange reactions in unlabeled nucleic acids
    Besik I Kankia
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA
    Nucleic Acids Res 32:e154. 2004
    ..Adding the replacement sequence initiates the release of the 'signal' oligonucleotide into solution, which is accompanied by ultraviolet absorption in long-wavelength range...
  2. ncbi request reprint The HIV-1 central DNA flap region contains a "flapping" third strand
    Besik I Kankia
    Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, United States
    Biophys Chem 127:64-8. 2007
    ....
  3. ncbi request reprint Binding of Mg2+ to single-stranded polynucleotides: hydration and optical studies
    Besik I Kankia
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 1479 Gortner Avenue, St Paul, Minnesota, MN 55108, USA
    Biophys Chem 104:643-54. 2003
    ..The evidence presented here indicates that Mg(2+) are able to bind specifically to single-stranded polynucleotides, and recognize their composition and backbone conformation...
  4. pmc Mg2+-induced triplex formation of an equimolar mixture of poly(rA) and poly(rU)
    Besik I Kankia
    Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, 1479 Gortner Avenue, St Paul, MN 55108, USA
    Nucleic Acids Res 31:5101-7. 2003
    ..The phase boundary corresponding to the transition between double and triple helical conformations lies near physiological salt concentrations and temperature...
  5. ncbi request reprint Inner-sphere complexes of divalent cations with single-stranded poly(rA) and poly(rU)
    Besik I Kankia
    Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota, Minneapolis, MN 55455, USA
    Biopolymers 74:232-9. 2004
    ....
  6. pmc A real-time assay for monitoring nucleic acid cleavage by quadruplex formation
    Besik I Kankia
    Department of Chemistry, University of Minnesota, MN 55455, USA
    Nucleic Acids Res 34:e141. 2006
    ..QFA can be used to study the mechanisms of protein-nucleic acid recognition. QFA is also a useful tool for dissecting individual nicking rates of a double-stranded cleavage...
  7. pmc Unfolding of DNA quadruplexes induced by HIV-1 nucleocapsid protein
    Besik I Kankia
    Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, USA
    Nucleic Acids Res 33:4395-403. 2005
    ....
  8. doi request reprint HIV-integrase aptamer folds into a parallel quadruplex: a thermodynamic study
    Sean Kelley
    Department of Chemistry, The Ohio State University, Columbus, OH 43210, USA
    Biophys Chem 155:82-8. 2011
    ..Taken together, both optical and thermodynamic studies performed here strongly support a parallel fold for the d(GGGT)(4) aptamer...
  9. doi request reprint Self-dissociative primers for nucleic acid amplification and detection based on DNA quadruplexes with intrinsic fluorescence
    Besik I Kankia
    Department of Chemistry, The Ohio State University, Columbus, OH 43210, USA
    Anal Biochem 409:59-65. 2011
    ..In addition, the quadruplex formation is accompanied by an increase in intrinsic fluorescence of the primers, allowing simple and accurate detection of product DNA...
  10. ncbi request reprint DNA oligonucleotide duplexes containing intramolecular platinated cross-links: energetics, hydration, sequence, and ionic effects
    Besik I Kankia
    Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, 68198, USA
    Biopolymers 65:218-27. 2002
    ..The overall results correlate nicely with the results reported in the available structural data of nuclear magnetic resonance solution studies...
  11. pmc Thermodynamic and hydration effects for the incorporation of a cationic 3-aminopropyl chain into DNA
    Ana Maria Soto
    Department of Pharmaceutical Sciences, University of Nebraska Medical Center, 986025 Nebraska Medical Center, Omaha, NE 68198 6025, USA
    Nucleic Acids Res 30:3171-80. 2002
    ..This indicates that incorporation of the aminopropyl chain induces a higher exposure of aromatic bases to the solvent, which may be consistent with a small and local bend in the 'modified' duplex...