J J Loor

Summary

Affiliation: University of Illinois
Country: USA

Publications

  1. doi request reprint Adipose tissue depots of Holstein cows are immune responsive: inflammatory gene expression in vitro
    M Mukesh
    Mammalian NutriPhysioGenomics, University of Illinois, Urbana, IL 61801, USA
    Domest Anim Endocrinol 38:168-78. 2010
  2. pmc Prepartum body condition score and plane of nutrition affect the hepatic transcriptome during the transition period in grazing dairy cows
    M Vailati-Riboni
    Department of Animal Sciences, University of Illinois, Urbana, 61801, USA
    BMC Genomics 17:854. 2016
  3. pmc iTRAQ-proteomics and bioinformatics analyses of mammary tissue from cows with clinical mastitis due to natural infection with Staphylococci aureus
    Jinming Huang
    Dairy Cattle Research Center, Shandong Academy of Agricultural Sciences, NO, 159 North of Industry Road, Jinan, Shandong 250131, China
    BMC Genomics 15:839. 2014
  4. pmc Hepatic Metabolic, Inflammatory, and Stress-Related Gene Expression in Growing Mice Consuming a Low Dose of Trans-10, cis-12-Conjugated Linoleic Acid
    Jing Li
    Division of Nutritional Sciences, Mammalian NutriPhysioGenomics, Department of Animal Sciences, University of Illinois, 1207 West Gregory Drive, Urbana IL61801, USA
    J Lipids 2012:571281. 2012
  5. pmc Dietary Lipid During Late-Pregnancy and Early-Lactation to Manipulate Metabolic and Inflammatory Gene Network Expression in Dairy Cattle Liver with a Focus on PPARs
    Haji Akbar
    Mammalian NutriPhysioGenomics Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana, Illinois, USA
    Gene Regul Syst Bio 7:103-23. 2013
  6. pmc A novel dynamic impact approach (DIA) for functional analysis of time-course omics studies: validation using the bovine mammary transcriptome
    Massimo Bionaz
    Department of Animal Sciences, University of Illinois, Urbana, Illinois, United States of America
    PLoS ONE 7:e32455. 2012
  7. pmc Trans-10, cis 12-Conjugated Linoleic Acid-Induced Milk Fat Depression Is Associated with Inhibition of PPARγ Signaling and Inflammation in Murine Mammary Tissue
    Anil K G Kadegowda
    Department of Animal and Avian Sciences, University of Maryland, College Park, MD 20742, USA
    J Lipids 2013:890343. 2013
  8. pmc Gene networks driving bovine mammary protein synthesis during the lactation cycle
    Massimo Bionaz
    Mammalian NutriPhysio Genomics, Department of Animal Sciences, University of Illinois, Urbana, IL 61801, USA
    Bioinform Biol Insights 5:83-98. 2011
  9. pmc Expression of metabolic, tissue remodeling, oxidative stress, and inflammatory pathways in mammary tissue during involution in lactating dairy cows
    Paola Piantoni
    Mammalian NutriPhysioGenomics
    Bioinform Biol Insights 4:85-97. 2010
  10. pmc Ruminant metabolic systems biology: reconstruction and integration of transcriptome dynamics underlying functional responses of tissues to nutrition and physiological state
    Massimo Bionaz
    Institute for Genomic Biology, University of Illinois, Urbana, IL, 61801
    Gene Regul Syst Bio 6:109-25. 2012

Collaborators

Detail Information

Publications72

  1. doi request reprint Adipose tissue depots of Holstein cows are immune responsive: inflammatory gene expression in vitro
    M Mukesh
    Mammalian NutriPhysioGenomics, University of Illinois, Urbana, IL 61801, USA
    Domest Anim Endocrinol 38:168-78. 2010
    ....
  2. pmc Prepartum body condition score and plane of nutrition affect the hepatic transcriptome during the transition period in grazing dairy cows
    M Vailati-Riboni
    Department of Animal Sciences, University of Illinois, Urbana, 61801, USA
    BMC Genomics 17:854. 2016
    ..A transcriptomic approach was used to evaluate potential interactions between prepartum body condition score (BCS) and feeding management in the weeks before calving on hepatic metabolism during the periparturient period...
  3. pmc iTRAQ-proteomics and bioinformatics analyses of mammary tissue from cows with clinical mastitis due to natural infection with Staphylococci aureus
    Jinming Huang
    Dairy Cattle Research Center, Shandong Academy of Agricultural Sciences, NO, 159 North of Industry Road, Jinan, Shandong 250131, China
    BMC Genomics 15:839. 2014
    ..The aim of the present study was to use isobaric tags for relative and absolute quantification (iTRAQ) to screen potential proteins associated with mastitis at late infectious stage...
  4. pmc Hepatic Metabolic, Inflammatory, and Stress-Related Gene Expression in Growing Mice Consuming a Low Dose of Trans-10, cis-12-Conjugated Linoleic Acid
    Jing Li
    Division of Nutritional Sciences, Mammalian NutriPhysioGenomics, Department of Animal Sciences, University of Illinois, 1207 West Gregory Drive, Urbana IL61801, USA
    J Lipids 2012:571281. 2012
    ..Results suggested that a chronic low dose of dietary CLA increases liver mass and lipid accumulation due to activation of lipogenesis and insufficient induction of LCFA oxidation and VLDL assembly/secretion...
  5. pmc Dietary Lipid During Late-Pregnancy and Early-Lactation to Manipulate Metabolic and Inflammatory Gene Network Expression in Dairy Cattle Liver with a Focus on PPARs
    Haji Akbar
    Mammalian NutriPhysioGenomics Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana, Illinois, USA
    Gene Regul Syst Bio 7:103-23. 2013
    ..At the levels supplemented, the change in the profile of metabolic genes after parturition in cows fed saturated fat suggested a greater capacity for uptake of fatty acids and intracellular handling without excessive storage of LD. ..
  6. pmc A novel dynamic impact approach (DIA) for functional analysis of time-course omics studies: validation using the bovine mammary transcriptome
    Massimo Bionaz
    Department of Animal Sciences, University of Illinois, Urbana, Illinois, United States of America
    PLoS ONE 7:e32455. 2012
    ..Results indicate the DIA is a biologically-sound approach for analysis of time-course experiments. This tool represents an alternative to ORA for functional analysis...
  7. pmc Trans-10, cis 12-Conjugated Linoleic Acid-Induced Milk Fat Depression Is Associated with Inhibition of PPARγ Signaling and Inflammation in Murine Mammary Tissue
    Anil K G Kadegowda
    Department of Animal and Avian Sciences, University of Maryland, College Park, MD 20742, USA
    J Lipids 2013:890343. 2013
    ..Overall, results from this study underscored the role of PPAR γ signaling on mammary lipogenic target regulation. The proinflammatory effect due to CLA could be related to inhibition of PPAR γ signaling...
  8. pmc Gene networks driving bovine mammary protein synthesis during the lactation cycle
    Massimo Bionaz
    Mammalian NutriPhysio Genomics, Department of Animal Sciences, University of Illinois, Urbana, IL 61801, USA
    Bioinform Biol Insights 5:83-98. 2011
    ..Furthermore, the existence of translational competition favoring the translation of milk protein transcripts was inferred from the combined dataset...
  9. pmc Expression of metabolic, tissue remodeling, oxidative stress, and inflammatory pathways in mammary tissue during involution in lactating dairy cows
    Paola Piantoni
    Mammalian NutriPhysioGenomics
    Bioinform Biol Insights 4:85-97. 2010
    ....
  10. pmc Ruminant metabolic systems biology: reconstruction and integration of transcriptome dynamics underlying functional responses of tissues to nutrition and physiological state
    Massimo Bionaz
    Institute for Genomic Biology, University of Illinois, Urbana, IL, 61801
    Gene Regul Syst Bio 6:109-25. 2012
    ..The ultimate goal is to visualize the complexity of the systems at study and uncover key molecular players involved in the tissue's adaptations to physiological state or nutrition...
  11. doi request reprint Postpartal subclinical endometritis alters transcriptome profiles in liver and adipose tissue of dairy cows.
    Haji Akbar
    Department of Animal Sciences, University of Illinois, Urbana, Illinois, USA
    Bioinform Biol Insights 8:45-63. 2014
    ..Results indicate that SCE in dairy cattle during early lactation induces molecular alterations in liver and adipose tissue indicative of immune activation and cellular stress...
  12. pmc Yin yang 1 and adipogenic gene network expression in longissimus muscle of beef cattle in response to nutritional management
    Sonia J Moisá
    Mammalian NutriPhysioGenomics, University of Illinois, Urbana, USA Department of Animal Sciences, University of Illinois, Urbana, USA
    Gene Regul Syst Bio 7:71-83. 2013
    ..Such response partly explains the greater carcass fat deposition observed in response to NWS...
  13. pmc Overfeeding Dairy Cattle During Late-Pregnancy Alters Hepatic PPARα-Regulated Pathways Including Hepatokines: Impact on Metabolism and Peripheral Insulin Sensitivity
    M Jawad Khan
    Department of Animal Sciences, Division of Nutritional Sciences, University of Illinois, Urbana, IL, USA Department of Biosciences, COMSATS Institute of Information Technology, Islamabad, Pakistan
    Gene Regul Syst Bio 8:97-111. 2014
    ..Postpartal responses in NEFA and FGF21 with OVE support a role of this hepatokine in diminishing adipose insulin sensitivity. ..
  14. pmc Application of Top-Down and Bottom-up Systems Approaches in Ruminant Physiology and Metabolism
    Khuram Shahzad
    Department of Animal Sciences, University of Illinois, Urbana Champaign, Urbana, Illinois, 61801, USA
    Curr Genomics 13:379-94. 2012
    ..We also explore the usefulness of tissue specific reconstructions (e.g., liver and adipose tissue) in cattle as a means to enhance productive efficiency...
  15. pmc Selection and reliability of internal reference genes for quantitative PCR verification of transcriptomics during the differentiation process of porcine adult mesenchymal stem cells
    Elisa Monaco
    Laboratory of Stem Cell Biology and Engineering, Department of Animal Sciences, University of Illinois at Urbana Champaign, 1207 West Gregory Drive, Urbana, 61801, Illinois, USA
    Stem Cell Res Ther 1:7. 2010
    ..The objective of this study was to find highly reliable internal-control genes (ICGs) for normalization of qPCR data from porcine adult mesenchymal stem cells induced to differentiate toward adipogenic and osteogenic lineages...
  16. pmc Functional annotation of novel lineage-specific genes using co-expression and promoter analysis
    Charu G Kumar
    Department of Animal Sciences, University of Illinois at Urbana Champaign, 210 Edward R Madigan Laboratory, 1201 W Gregory Dr, Urbana, IL 61801, USA
    BMC Genomics 11:161. 2010
    ..The aim of the present study was to infer functions of previously uncharacterized lineage-specific genes (LSGs) using co-expression, promoter, pathway and network analysis...
  17. pmc Functional and gene network analyses of transcriptional signatures characterizing pre-weaned bovine mammary parenchyma or fat pad uncovered novel inter-tissue signaling networks during development
    Paola Piantoni
    Department of Animal Sciences, University of Illinois, Urbana, IL 61801, USA
    BMC Genomics 11:331. 2010
    ..Data were mined to uncover potential crosstalk through the analyses of signaling molecules preferentially expressed in one tissue relative to the other...
  18. pmc Gene networks driving bovine milk fat synthesis during the lactation cycle
    Massimo Bionaz
    Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana, 61801 Illinois, USA
    BMC Genomics 9:366. 2008
    ..mRNA expression was coupled with milk fatty acid (FA) composition and calculated indexes of FA desaturation and de novo synthesis by the mammary gland...
  19. doi request reprint Functional adaptations of the transcriptome to mastitis-causing pathogens: the mammary gland and beyond
    Juan J Loor
    Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois at Urbana Champaign, Urbana, IL 61801, USA
    J Mammary Gland Biol Neoplasia 16:305-22. 2011
    ....
  20. doi request reprint ASAS centennial paper: Lactation biology for the twenty-first century
    J J Loor
    Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801, USA
    J Anim Sci 87:813-24. 2009
    ....
  21. doi request reprint Hepatic global DNA and peroxisome proliferator-activated receptor alpha promoter methylation are altered in peripartal dairy cows fed rumen-protected methionine
    J S Osorio
    Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801
    J Dairy Sci 99:234-44. 2016
    ..Further research is needed to study more closely the mechanistic connections between global DNA and promoter region-specific PPARA methylation with PPARA expression and functional outcomes in liver. ..
  22. doi request reprint Liver lipid content and inflammometabolic indices in peripartal dairy cows are altered in response to prepartal energy intake and postpartal intramammary inflammatory challenge
    D E Graugnard
    Mammalian NutriPhysioGenomics, Department of Animal Sciences, University of Illinois, Urbana, IL 61801, USA
    J Dairy Sci 96:918-35. 2013
    ..These data suggest that overfeeding a moderate-energy diet prepartum alters the response of the cow to an intramammary challenge after calving and may predispose it to sustained liver lipidosis...
  23. doi request reprint Effect of the level of maternal energy intake prepartum on immunometabolic markers, polymorphonuclear leukocyte function, and neutrophil gene network expression in neonatal Holstein heifer calves
    J S Osorio
    Mammalian NutriPhysioGenomics, University of Illinois, 1207 West Gregory Drive, Urbana 61801, USA
    J Dairy Sci 96:3573-87. 2013
    ..It might be feasible to design nutrient supplements to fortify colostrum in a way that metabolic and immunologic capabilities of the calf are improved...
  24. doi request reprint Blood immunometabolic indices and polymorphonuclear neutrophil function in peripartum dairy cows are altered by level of dietary energy prepartum
    D E Graugnard
    Mammalian NutriPhysioGenomics Laboratory, Department of Animal Sciences, University of Illinois, Urbana 61801, USA
    J Dairy Sci 95:1749-58. 2012
    ..For vitamin A, the decrease was observed in overfed cows (47.3 vs. 27.5 μg/100 mL). Overall, overfeeding energy and higher energy status prepartum led to the surge of insulin and had a transient effect on metabolism postpartum...
  25. doi request reprint Supplementing Zn, Mn, and Cu from amino acid complexes and Co from cobalt glucoheptonate during the peripartal period benefits postpartal cow performance and blood neutrophil function
    J S Osorio
    Mammalian NutriPhysioGenomics, University of Illinois, Urbana 61801 Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801
    J Dairy Sci 99:1868-83. 2016
    ....
  26. doi request reprint Effects of the peroxisome proliferator-activated receptor-alpha agonists clofibrate and fish oil on hepatic fatty acid metabolism in weaned dairy calves
    N B Litherland
    Department of Animal Sciences, University of Illinois, Urbana 61801, USA
    J Dairy Sci 93:2404-18. 2010
    ..Applications of PPARalpha agonists may be of interest to increase the rate of hepatic fatty acid oxidation and decrease triacylglycerol accumulation in periparturient dairy cows...
  27. doi request reprint Feed restriction, but not l-carnitine infusion, alters the liver transcriptome by inhibiting sterol synthesis and mitochondrial oxidative phosphorylation and increasing gluconeogenesis in mid-lactation dairy cows
    H Akbar
    Department of Animal Sciences, University of Illinois, Urbana 61801, Illinois, USA
    J Dairy Sci 96:2201-13. 2013
    ..The data also indicated an increase of flux toward gluconeogenesis. We interpreted those results as a likely response of the liver to spare energy and provide glucose for the lactating mammary gland during feed deprivation...
  28. doi request reprint Bioinformatics analysis of microRNA and putative target genes in bovine mammary tissue infected with Streptococcus uberis
    A Naeem
    Mammalian NutriPhysioGenomics, and Department of Animal Sciences, University of Illinois, Urbana 61801, USA
    J Dairy Sci 95:6397-408. 2012
    ..Differential expression of miRNA supports the view from nonruminant cells/tissues that certain miRNA might be essential for the tissue's adaptive response to infection...
  29. doi request reprint Corium tissue expression of genes associated with inflammation, oxidative stress, and keratin formation in relation to lameness in dairy cows
    J S Osorio
    Department of Animal Sciences, University of Illinois, 1207 West Gregory Drive, Urbana 61801, USA
    J Dairy Sci 95:6388-96. 2012
    ..More comprehensive studies of the hoof transcriptome are required to improve our understanding of the mechanisms that link environmental and dietary factors to development of lameness...
  30. doi request reprint Identification of internal control genes for quantitative polymerase chain reaction in mammary tissue of lactating cows receiving lipid supplements
    A K G Kadegowda
    Department of Animal and Avian Sciences, University of Maryland, College Park 20742, USA
    J Dairy Sci 92:2007-19. 2009
    ..These novel ICG could be used for normalization in similar studies as alternatives to the less-reliable ACTB, GAPDH, or B2M...
  31. doi request reprint Body condition score and plane of nutrition prepartum affect adipose tissue transcriptome regulators of metabolism and inflammation in grazing dairy cows during the transition period
    M Vailati-Riboni
    Department of Animal Sciences, University of Illinois, Urbana 61801
    J Dairy Sci 99:758-70. 2016
    ..Data support the use of a controlled feed restriction prepartum in optimally conditioned cows, as well as the use of a higher level of dietary energy in under-conditioned cows...
  32. doi request reprint Rumen-protected methionine compared with rumen-protected choline improves immunometabolic status in dairy cows during the peripartal period
    Z Zhou
    Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801
    J Dairy Sci 99:8956-8969. 2016
    ..Overall, liver and blood biomarker analyses revealed favorable changes in liver function, inflammation status, and immune response in Met-supplemented cows...
  33. doi request reprint Far-off and close-up dry matter intake modulate indicators of immunometabolic adaptations to lactation in subcutaneous adipose tissue of pasture-based transition dairy cows
    M Vailati-Riboni
    Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801
    J Dairy Sci . 2017
    ..Furthermore, to ensure a favorable transition, cows should be subjected to a small feed restriction in the close-up period, irrespective of far-off nutritional management...
  34. doi request reprint Overfeeding a moderate energy diet prepartum does not impair bovine subcutaneous adipose tissue insulin signal transduction and induces marked changes in peripartal gene network expression
    P Ji
    Department of Animal Sciences, University of Illinois, Urbana 61801, USA
    J Dairy Sci 95:4333-51. 2012
    ..Thus, identifying specific nutrients capable of activating PPARγ after calving in AT might help accelerate its replenishment. A regulatory network encompassing the genes and physiological measurements obtained is proposed...
  35. doi request reprint Change in subcutaneous adipose tissue metabolism and gene network expression during the transition period in dairy cows, including differences due to sire genetic merit
    M J Khan
    Mammalian NutriPhysioGenomics, Department of Animal Sciences, University of Illinois, Urbana 61801, USA
    J Dairy Sci 96:2171-82. 2013
    ..These results confirm that gene transcription is a major control mechanism for AT lipogenesis during early lactation, but that control of lipolysis is likely primarily by posttranslational mechanisms...
  36. doi request reprint Adipose and liver gene expression profiles in response to treatment with a nonsteroidal antiinflammatory drug after calving in grazing dairy cows
    M Vailati Riboni
    Department of Animal Sciences, University of Illinois, Urbana 61801
    J Dairy Sci 98:3079-85. 2015
    ....
  37. doi request reprint Biomarkers of inflammation, metabolism, and oxidative stress in blood, liver, and milk reveal a better immunometabolic status in peripartal cows supplemented with Smartamine M or MetaSmart
    J S Osorio
    Mammalian NutriPhysioGenomics, University of Illinois, 1207 West Gregory Drive, Urbana 61801 Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, 1207 West Gregory Drive, Urbana 61801
    J Dairy Sci 97:7437-50. 2014
    ..Overall, biomarker analyses in blood and tissue indicate that the beneficial effect of feeding SM and MS on postpartal cow performance is due in part to a better immunometabolic status...
  38. doi request reprint Role of metabolic and cellular proliferation genes in ruminal development in response to enhanced plane of nutrition in neonatal Holstein calves
    A Naeem
    Department of Animal Sciences, University of Illinois, Urbana 61801, USA
    J Dairy Sci 95:1807-20. 2012
    ..Elucidating ligands of PPARD may provide the means for nutritional regulation of rumen development...
  39. doi request reprint Long-chain fatty acid effects on peroxisome proliferator-activated receptor-alpha-regulated genes in Madin-Darby bovine kidney cells: optimization of culture conditions using palmitate
    B J Thering
    Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801, USA
    J Dairy Sci 92:2027-37. 2009
    ..Overall, results indicated that a 6-h incubation with free LCFA and addition of insulin was suitable to detect marked effects on mRNA expression of PPARalpha target genes in MDBK cells...
  40. doi request reprint Circulating amino acids in blood plasma during the peripartal period in dairy cows with different liver functionality index
    Z Zhou
    Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801
    J Dairy Sci 99:2257-67. 2016
    ..Whether these AA played a direct role in the greater milk production remains to be determined...
  41. doi request reprint Prepartal dietary energy level affects peripartal bovine blood neutrophil metabolic, antioxidant, and inflammatory gene expression
    Z Zhou
    Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801, P R China
    J Dairy Sci 98:5492-505. 2015
    ..These adaptations observed in PMNL did not seem to be detrimental for production. ..
  42. doi request reprint Prepartal Energy Intake Alters Blood Polymorphonuclear Leukocyte Transcriptome During the Peripartal Period in Holstein Cows
    A Agrawal
    Division of Nutritional Sciences, Department of Animal Sciences, University of Illinois at Urbana Champaign, Urbana, IL, USA
    Bioinform Biol Insights 11:1177932217704667. 2017
    ..The widespread, transcriptome-level changes captured here confirm the importance of dietary energy adjustments around calving on the immune system...
  43. doi request reprint Ethyl-cellulose rumen-protected methionine enhances performance during the periparturient period and early lactation in Holstein dairy cows
    F Batistel
    Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801
    J Dairy Sci 100:7455-7467. 2017
    ..8:1 in metabolizable protein improved dairy cow performance from parturition through 60 DIM. The greater milk production was, at least in part, driven by the greater voluntary DMI and better liver function...
  44. doi request reprint Reticulo-rumen mass, epithelium gene expression, and systemic biomarkers of metabolism and inflammation in Holstein dairy cows fed a high-energy diet
    J M Arroyo
    Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801 Departamento de Nutrición Animal, Instituto de Producción Animal, Facultad de Veterinaria, Universidad de la Republica, Ruta 1 km 42 5, 80100, San Jose, Uruguay
    J Dairy Sci 100:9352-9360. 2017
    ..The relevance of these findings to the nutritional management of pregnant dry cows merits further research...
  45. doi request reprint Level of nutrient intake affects mammary gland gene expression profiles in preweaned Holstein heifers
    P Piantoni
    Department of Animal Sciences, University of Illinois, Urbana, Illinois 61801, USA
    J Dairy Sci 95:2550-61. 2012
    ..The biological significance of these results to future milk production remains to be elucidated...
  46. doi request reprint Maternal rumen-protected methionine supplementation and its effect on blood and liver biomarkers of energy metabolism, inflammation, and oxidative stress in neonatal Holstein calves
    C B Jacometo
    NUPEEC Núcleo de Ensino, Pesquisa e Extensão em Pecuária, Departamento de Clínicas Veterinária, Programa de Pós Graduação em Biotecnologia, Universidade Federal de Pelotas, 96010 900, Pelotas, RS, Brazil Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801
    J Dairy Sci 99:6753-63. 2016
    ....
  47. doi request reprint Dietary-induced negative energy balance has minimal effects on innate immunity during a Streptococcus uberis mastitis challenge in dairy cows during midlactation
    K M Moyes
    Mammalian NutriPhysioGenomics, Department of Animal Sciences, University of Illinois, Urbana, Illinois 61801, USA
    J Dairy Sci 92:4301-16. 2009
    ..Our results indicate that cows subjected to dietary-induced NEB during midlactation had relatively minimal alterations in immune function...
  48. doi request reprint Ethyl-cellulose rumen-protected methionine alleviates inflammation and oxidative stress and improves neutrophil function during the periparturient period and early lactation in Holstein dairy cows
    F Batistel
    Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801
    J Dairy Sci . 2017
    ..8:1 in the metabolizable protein during the periparturient period and early lactation is an effective approach to help mitigate oxidative stress and inflammation as well as enhance liver and neutrophil function in dairy cows...
  49. doi request reprint Corium molecular biomarkers reveal a beneficial effect on hoof transcriptomics in peripartal dairy cows supplemented with zinc, manganese, and copper from amino acid complexes and cobalt from cobalt glucoheptonate
    J S Osorio
    Mammalian NutriPhysioGenomics, University of Illinois, 1207 West Gregory Drive, Urbana 61801 Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, 1207 West Gregory Drive, Urbana 61801
    J Dairy Sci 99:9974-9982. 2016
    ..The hoof biopsy procedure used in the present study should be further perfected and implemented in future lameness research to expand our understanding of hoof biology in dairy cows...
  50. doi request reprint Better postpartal performance in dairy cows supplemented with rumen-protected methionine compared with choline during the peripartal period
    Z Zhou
    Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801
    J Dairy Sci 99:8716-8732. 2016
    ..Results from the present study indicate that peripartal supplementation of rumen-protected Met but not CHOL has positive effects on cow performance...
  51. doi request reprint Smartamine M and MetaSmart supplementation during the peripartal period alter hepatic expression of gene networks in 1-carbon metabolism, inflammation, oxidative stress, and the growth hormone-insulin-like growth factor 1 axis pathways
    J S Osorio
    Mammalian NutriPhysioGenomics, University of Illinois, 1207 West Gregory Drive, Urbana 61801 Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, 1207 West Gregory Drive, Urbana 61801
    J Dairy Sci 97:7451-64. 2014
    ..These compounds likely are in high demand during the peripartum period. ..
  52. doi request reprint Postpartal immunometabolic gene network expression and function in blood neutrophils are altered in response to prepartal energy intake and postpartal intramammary inflammatory challenge
    K M Moyes
    Department of Animal and Avian Sciences, University of Maryland, College Park 20742 Electronic address
    J Dairy Sci 97:2165-77. 2014
    ..The current study provides new linkages among prepartal feed energy intake, metabolism, and immune response of blood PMN and risk of disease during early lactation. ..
  53. doi request reprint Hepatic purinergic signaling gene network expression and its relationship with inflammation and oxidative stress biomarkers in blood from peripartal dairy cattle
    J Seo
    Department of Agricultural Biotechnology, Research Institute for Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, Daehak dong, Kwanak gu, Seoul 151 742, Republic of Korea Mammalian NutriPhysioGenomics, Department of Animal Sciences, and Division of Nutritional Sciences, University of Illinois, 1207 West Gregory Drive, Urbana 61801
    J Dairy Sci 97:861-73. 2014
    ..The correlation analysis provided evidence of a link between purinergic signaling genes and biomarkers of inflammation and oxidative stress. ..
  54. doi request reprint Endocannabinoid system and proopiomelanocortin gene expression in peripartal bovine liver in response to prepartal plane of nutrition
    M J Khan
    Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana, IL 61801, USA
    J Anim Physiol Anim Nutr (Berl) 96:907-19. 2012
    ..Such responses may play a role in the physiological adaptations to the onset of lactation, including energy balance and feed intake...
  55. doi request reprint Short communication: Endoplasmic reticulum stress gene network expression in bovine mammary tissue during the lactation cycle
    G Invernizzi
    Mammalian NutriPhysioGenomics, Division of Nutritional Sciences, Department of Animal Sciences, University of Illinois, Urbana, Illinois 61801, USA
    J Dairy Sci 95:2562-6. 2012
    ..In the context of lactation, however, transcriptional changes in the ER stress pathway at different stages of the lactation cycle are a normal aspect of the tissue's adaptation to the changing physiological state...
  56. doi request reprint The effect of calving in the summer on the hepatic transcriptome of Holstein cows during the peripartal period
    K Shahzad
    Department of Animal Sciences and Division of Nutritional Sciences, Urbana 61801, Italy Illinois Informatics Institute, University of Illinois, Urbana 61801, Italy
    J Dairy Sci 98:5401-13. 2015
    ....
  57. doi request reprint Grain challenge affects systemic and hepatic molecular biomarkers of inflammation, stress, and metabolic responses to a greater extent in Holstein than Jersey cows
    T Xu
    Department of Clinical Veterinary Medicine, Nanjing Agricultural University, Nanjing, PR China, 210095 Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana
    J Dairy Sci 100:9153-9162. 2017
    ..It remains to be determined if these acute responses to a grain challenge can elicit long-term liver dysfunction, which could negatively affect welfare of the cow...
  58. doi request reprint Differences in liver functionality indexes in peripartal dairy cows fed rumen-protected methionine or choline are associated with performance, oxidative stress status, and plasma amino acid profiles
    Z Zhou
    Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801 Department of Animal and Veterinary Sciences, Clemson University, SC 29634
    J Dairy Sci 100:6720-6732. 2017
    ..Further studies on the applicability of these biomarkers to monitor transition success appears warranted...
  59. doi request reprint Inflammation- and lipid metabolism-related gene network expression in visceral and subcutaneous adipose depots of Holstein cows
    P Ji
    Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801
    J Dairy Sci 97:3441-8. 2014
    ....
  60. doi request reprint Peroxisome proliferator-activated receptor-gamma activation and long-chain fatty acids alter lipogenic gene networks in bovine mammary epithelial cells to various extents
    A K G Kadegowda
    Department of Animal and Avian Sciences, University of Maryland, College Park, Maryland 20742, USA
    J Dairy Sci 92:4276-89. 2009
    ..The coordinated upregulation of lipogenic gene networks in response to ROSI and saturated LCFA offers support for PPARG activation in regulating bovine milk fat synthesis...
  61. doi request reprint Overfeeding energy upregulates peroxisome proliferator-activated receptor (PPAR)γ-controlled adipogenic and lipolytic gene networks but does not affect proinflammatory markers in visceral and subcutaneous adipose depots of Holstein cows
    P Ji
    Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801
    J Dairy Sci 97:3431-40. 2014
    ..Our results do not support an overt inflammatory response in adipose tissues in response to an 8-wk energy overfeeding...
  62. doi request reprint Supplemental Smartamine M or MetaSmart during the transition period benefits postpartal cow performance and blood neutrophil function
    J S Osorio
    Mammalian NutriPhysioGenomics, and University of Illinois, 1207 West Gregory Drive, Urbana 61801 Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, 1207 West Gregory Drive, Urbana 61801
    J Dairy Sci 96:6248-63. 2013
    ..Supplemental MS or SM resulted in a tendency for lower incidence of ketosis postpartum. Although supplemental MS or SM did not decrease liver triacylglycerol, it improved milk production-related traits by enhancing voluntary DMI...
  63. doi request reprint Adipose tissue lipogenic gene networks due to lipid feeding and milk fat depression in lactating cows
    B J Thering
    Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana, Illinois 61801, USA
    J Dairy Sci 92:4290-300. 2009
    ....
  64. doi request reprint Visceral adipose tissue mass in nonlactating dairy cows fed diets differing in energy density(1)
    J K Drackley
    Department of Animal Sciences, University of Illinois, Urbana 61801
    J Dairy Sci 97:3420-30. 2014
    ..The similar final BCS between HE and LE cows demonstrates that BCS may lack sensitivity to detect differences in visceral fat deposition that might increase risk for peripartal diseases and disorders...
  65. doi request reprint Effects of level of nutrient intake and age on mammalian target of rapamycin, insulin, and insulin-like growth factor-1 gene network expression in skeletal muscle of young Holstein calves
    P Wang
    College of Animal Science and Technology, Northwest A and F University, Yangling, 712100, China Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801
    J Dairy Sci 97:383-91. 2014
    ..Those networks may play a crucial role in coordinating neonatal muscle growth and metabolism in response to level of nutrient intake. ..
  66. doi request reprint Body condition score at calving affects systemic and hepatic transcriptome indicators of inflammation and nutrient metabolism in grazing dairy cows
    H Akbar
    Department of Animal Sciences, University of Illinois, Urbana 61801
    J Dairy Sci 98:1019-32. 2015
    ..5 or 5.5 relative to BCS 4.5. ..
  67. doi request reprint Clock circadian regulator (CLOCK) gene network expression patterns in bovine adipose, liver, and mammary gland at 3 time points during the transition from pregnancy into lactation
    M Wang
    College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, Jiangsu Province, P R China Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, Urbana 61801
    J Dairy Sci 98:4601-12. 2015
    ....
  68. doi request reprint Purinergic signaling gene network expression in bovine polymorphonuclear neutrophils during the peripartal period
    J Seo
    Department of Agricultural Biotechnology, Research Institute for Agriculture and Life Sciences, College of Agriculture and Life Sciences, Seoul National University, Daehak dong, Kwanak gu, Seoul 151 742, Republic of Korea Mammalian NutriPhysioGenomics, Department of Animal Sciences and Division of Nutritional Sciences, University of Illinois, 1207 West Gregory Drive, Urbana 61801
    J Dairy Sci 96:7675-83. 2013
    ..The reduction in key immune responses, such as cell adhesion and chemotaxis, by bovine PMNL could partly be a function of changes in mRNA expression of genes associated with purinergic signaling...
  69. doi request reprint MicroRNA expression patterns in the bovine mammary gland are affected by stage of lactation
    M Wang
    State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, PR China
    J Dairy Sci 95:6529-35. 2012
    ..The specific roles of these miR during lactation will require further research...
  70. ncbi request reprint Housekeeping gene expression in bovine liver is affected by physiological state, feed intake, and dietary treatment
    N A Janovick-Guretzky
    Department of Animal Sciences, University of Illinois, Urbana 61801, USA
    J Dairy Sci 90:2246-52. 2007
    ....