J L Spearow

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Genetic variation in susceptibility to endocrine disruption by estrogen in mice
    J L Spearow
    Section of Neurobiology, Physiology and Behavior, University of California at Davis, Davis, CA 95616, USA
    Science 285:1259-61. 1999
  2. ncbi request reprint Genetic control of hormone-induced ovulation rate in mice
    J L Spearow
    Section of Neurobiology, Physiology and Behavior, University of California at Davis, Davis, California 95616, USA
    Biol Reprod 61:851-6. 1999
  3. ncbi request reprint Mapping genes that control hormone-induced ovulation rate in mice
    J L Spearow
    Section of Neurobiology, Physiology and Behavior, University of California at Davis, Davis, California 95616, USA
    Biol Reprod 61:857-72. 1999
  4. ncbi request reprint Reassessment of models used to test xenobiotics for oestrogenic potency is overdue
    J L Spearow
    Section of Neurobiology, Physiology and Behavior, University of California at Davis, Davis, CA 95616, USA
    Hum Reprod 16:1027-9. 2001
  5. ncbi request reprint Genetic variation in physiological sensitivity to estrogen in mice
    J L Spearow
    Section of Neurobiology, Physiology and Behavior, University of California at Davis, 95616, USA
    APMIS 109:356-64. 2001
  6. ncbi request reprint Chromosomal mapping and expression levels of a mouse soluble epoxide hydrolase gene
    D F Grant
    Department of Entomology and Environmental Toxicology, University of California, Davis, CA 95616
    Pharmacogenetics 4:64-72. 1994
  7. ncbi request reprint P450 (cytochrome) oxidoreductase (Por) maps to mouse chromosome 5, not chromosome 6
    J L Spearow
    Section of Neurobiology, Physiology and Behavior, University of California at Davis 95616, USA
    Mamm Genome 6:558-9. 1995

Collaborators

  • B A Taylor
  • D F Grant
  • B D Hammock
  • S Edelhoff
  • D H Storms
  • D A Adler
  • C M Disteche

Detail Information

Publications7

  1. ncbi request reprint Genetic variation in susceptibility to endocrine disruption by estrogen in mice
    J L Spearow
    Section of Neurobiology, Physiology and Behavior, University of California at Davis, Davis, CA 95616, USA
    Science 285:1259-61. 1999
    ..Product safety bioassays conducted with animals selected for fecundity may greatly underestimate disruption of male reproductive development by estradiol and environmental estrogenic compounds...
  2. ncbi request reprint Genetic control of hormone-induced ovulation rate in mice
    J L Spearow
    Section of Neurobiology, Physiology and Behavior, University of California at Davis, Davis, California 95616, USA
    Biol Reprod 61:851-6. 1999
    ..This study demonstrates genetic variation in HIOR both within and between mouse subspecies, and provides confirmation that genetic differences are a major source of variation in the regulation of ovarian responsiveness to gonadotropins...
  3. ncbi request reprint Mapping genes that control hormone-induced ovulation rate in mice
    J L Spearow
    Section of Neurobiology, Physiology and Behavior, University of California at Davis, Davis, California 95616, USA
    Biol Reprod 61:857-72. 1999
    ..These and closely linked syntenic molecular markers will enable a more accurate prediction of ovarian responsiveness to gonadotropins and provide selection criteria for improving reproductive performance in diverse mammalian species...
  4. ncbi request reprint Reassessment of models used to test xenobiotics for oestrogenic potency is overdue
    J L Spearow
    Section of Neurobiology, Physiology and Behavior, University of California at Davis, Davis, CA 95616, USA
    Hum Reprod 16:1027-9. 2001
    ..Such sensitive strains would be even more optimal for testing chemicals for endocrine disruptor activity...
  5. ncbi request reprint Genetic variation in physiological sensitivity to estrogen in mice
    J L Spearow
    Section of Neurobiology, Physiology and Behavior, University of California at Davis, 95616, USA
    APMIS 109:356-64. 2001
    ..These and other findings emphasize the need to identify and study genetic variation in sensitivity to estrogen in laboratory animal models used to assess the risk of xenobiotic estrogen exposure...
  6. ncbi request reprint Chromosomal mapping and expression levels of a mouse soluble epoxide hydrolase gene
    D F Grant
    Department of Entomology and Environmental Toxicology, University of California, Davis, CA 95616
    Pharmacogenetics 4:64-72. 1994
    ..Northern blotting analysis showed that soluble epoxide hydrolase mRNA levels were correlated with the relative level of soluble epoxide hydrolase enzyme activity and soluble epoxide hydrolase protein in all three mouse strains...
  7. ncbi request reprint P450 (cytochrome) oxidoreductase (Por) maps to mouse chromosome 5, not chromosome 6
    J L Spearow
    Section of Neurobiology, Physiology and Behavior, University of California at Davis 95616, USA
    Mamm Genome 6:558-9. 1995