Raymond M Welsh
Affiliation: University of Massachusetts Medical School
- ..2009; Rutishauser et al., 2009; Shin et al., 2009) indicate that the transcriptional repressor Blimp-1 promotes the development of short-lived effector cells and regulates clonal exhaustion. ..
- Welsh R, Waggoner S. NK cells controlling virus-specific T cells: Rheostats for acute vs. persistent infections. Virology. 2013;435:37-45 pubmed publisher..This subsequent change in T cell dynamics can alter patterns of immunopathology and persistence and implicates NK cells as rheostat-like regulators of persistent infections. ..
- Urban S, Berg L, Welsh R. Type 1 interferon licenses naïve CD8 T cells to mediate anti-viral cytotoxicity. Virology. 2016;493:52-9 pubmed publisher..We suggest that this rapid and sensitive effector function of IFN-conditioned naïve CD8 T cells may play a role in pathogen control and help ward off superinfections...