Affiliation: Wyeth Research
- Liu K, Samuel M, Tillett J, Hennan J, Mekonnen B, Soloveva V, et al. High-throughput screening for Kv1.3 channel blockers using an improved FLIPR-based membrane-potential assay. J Biomol Screen. 2010;15:185-95 pubmed publisher..Some compounds possess nanomolar potency, indicating that the FLIPR assay is effective for successfully identifying K(+) channel blockers as novel drug candidates...