Z Jay Chen

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Photon spectrometry for the determination of the dose-rate constant of low-energy photon-emitting brachytherapy sources
    Zhe Jay Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Med Phys 34:1412-30. 2007
  2. pmc On the need to compensate for edema-induced dose reductions in preplanned (131)Cs prostate brachytherapy
    Z Jay Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, P O Box 208040, New Haven, CT 06510 1234, USA
    Int J Radiat Oncol Biol Phys 70:303-10. 2008
  3. ncbi request reprint Silver fluorescent x-ray yield and its influence on the dose rate constant for nine low-energy brachytherapy source models
    Ravinder Nath
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Med Phys 34:3785-93. 2007
  4. pmc Constrained non-rigid registration for use in image-guided adaptive radiotherapy
    W H Greene
    Department of Biomedical Engineering, Yale University, New Haven, CT 06520, USA
    Med Image Anal 13:809-17. 2009
  5. pmc A photon spectrometric dose-rate constant determination for the Advantage Pd-103 brachytherapy source
    Zhe Jay Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Med Phys 37:672-4. 2010
  6. pmc Experimental characterization of the dosimetric properties of a newly designed I-Seed model AgX100 ¹²⁵I interstitial brachytherapy source
    Zhe Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06510, USA
    Brachytherapy 11:476-82. 2012
  7. pmc Impact of source-production revision on the dose-rate constant of 131Cs interstitial brachytherapy sources
    Zhe Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Med Phys 37:3607-10. 2010
  8. ncbi request reprint Dosimetric effects of edema in permanent prostate seed implants: a rigorous solution
    Z Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06504, USA
    Int J Radiat Oncol Biol Phys 47:1405-19. 2000
  9. pmc A systematic evaluation of the dose-rate constant determined by photon spectrometry for 21 different models of low-energy photon-emitting brachytherapy sources
    Zhe Jay Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA
    Phys Med Biol 55:6089-104. 2010
  10. pmc The impact of prostate edema on cell survival and tumor control after permanent interstitial brachytherapy for early stage prostate cancers
    Zhe Jay Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA
    Phys Med Biol 56:4895-912. 2011

Research Grants

Detail Information

Publications17

  1. ncbi request reprint Photon spectrometry for the determination of the dose-rate constant of low-energy photon-emitting brachytherapy sources
    Zhe Jay Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Med Phys 34:1412-30. 2007
    ....
  2. pmc On the need to compensate for edema-induced dose reductions in preplanned (131)Cs prostate brachytherapy
    Z Jay Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, P O Box 208040, New Haven, CT 06510 1234, USA
    Int J Radiat Oncol Biol Phys 70:303-10. 2008
    ..The purpose of this work was to examine whether these dose reductions should be actively compensated for and to estimate the magnitude of the additional irradiation needed for dose compensation...
  3. ncbi request reprint Silver fluorescent x-ray yield and its influence on the dose rate constant for nine low-energy brachytherapy source models
    Ravinder Nath
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Med Phys 34:3785-93. 2007
    ..This study concludes that the differences in silver fluorescent yield are the primary causes of the variable dose rate constant observed among these source models...
  4. pmc Constrained non-rigid registration for use in image-guided adaptive radiotherapy
    W H Greene
    Department of Biomedical Engineering, Yale University, New Haven, CT 06520, USA
    Med Image Anal 13:809-17. 2009
    ..Each adapted dose plan improved performance by lowering radiation distribution to the rectum and bladder while increasing or maintaining radiation distribution to the prostate...
  5. pmc A photon spectrometric dose-rate constant determination for the Advantage Pd-103 brachytherapy source
    Zhe Jay Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Med Phys 37:672-4. 2010
    ..The aim of this work was to perform an additional dose-rate constant (lamda) determination using a recently established photon spectrometry technique (PST) that is independent of the published TLD and Monte Carlo techniques...
  6. pmc Experimental characterization of the dosimetric properties of a newly designed I-Seed model AgX100 ¹²⁵I interstitial brachytherapy source
    Zhe Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06510, USA
    Brachytherapy 11:476-82. 2012
    ..To measure the dosimetric properties of the Model AgX100 ¹²⁵I source for interstitial brachytherapy...
  7. pmc Impact of source-production revision on the dose-rate constant of 131Cs interstitial brachytherapy sources
    Zhe Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Med Phys 37:3607-10. 2010
    ..In 2006, this source model underwent a Rev.2 production revision. The aim of this work was to investigate the dosimetric influences of the Rev.2 production revision using high-resolution photon spectrometry...
  8. ncbi request reprint Dosimetric effects of edema in permanent prostate seed implants: a rigorous solution
    Z Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06504, USA
    Int J Radiat Oncol Biol Phys 47:1405-19. 2000
    ..To derive a rigorous analytic solution to the dosimetric effects of prostate edema so that its impact on the conventional pre-implant and post-implant dosimetry can be studied for any given radioactive isotope and edema characteristics...
  9. pmc A systematic evaluation of the dose-rate constant determined by photon spectrometry for 21 different models of low-energy photon-emitting brachytherapy sources
    Zhe Jay Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06520, USA
    Phys Med Biol 55:6089-104. 2010
    ..These results demonstrate that the PST is an accurate and robust technique for the determination of the dose-rate constant for low-energy brachytherapy sources...
  10. pmc The impact of prostate edema on cell survival and tumor control after permanent interstitial brachytherapy for early stage prostate cancers
    Zhe Jay Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA
    Phys Med Biol 56:4895-912. 2011
    ..There is a clear need to consider the effects of prostate edema during the planning and evaluation of permanent interstitial brachytherapy treatments for prostate cancer...
  11. pmc A constrained non-rigid registration algorithm for use in prostate image-guided radiotherapy
    W H Greene
    Department of Biomedical Engineering, Yale University, New Haven, CT, USA
    Med Image Comput Comput Assist Interv 11:780-8. 2008
    ..Each updated treatment plan outperformed the original treatment plan by increasing radiation dosage to the prostate and lowering radiation dosage to the rectum and bladder...
  12. ncbi request reprint Optimum timing for image-based dose evaluation of 125I and 103PD prostate seed implants
    N Yue
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT 06510, USA
    Int J Radiat Oncol Biol Phys 45:1063-72. 1999
    ..This study uses a biomathematical model to simulate edema and its resolution on 29 patients, so that the optimum time to obtain image scans and perform dose evaluation can be investigated and estimated...
  13. ncbi request reprint Dose rate constant and energy spectrum of interstitial brachytherapy sources
    Z Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520-8040, USA
    Med Phys 28:86-96. 2001
    ....
  14. ncbi request reprint A minimax entropy registration framework for patient setup verification in radiotherapy
    R Bansal
    Department of Electrical Engineering and Department of Diagnostic Radiology, Yale University, New Haven, CT 06520 8042, USA
    Comput Aided Surg 4:287-304. 1999
    ..However, since the prostate can move with respect to the pelvic bone, we propose using ultrasound images to quantify this movement...
  15. ncbi request reprint Long-term complications with prostate implants: iodine-125 vs. palladium-103
    R E Peschel
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520 8040, USA
    Radiat Oncol Investig 7:278-88. 1999
    ..The implications of these findings are discussed in terms of future research directions for prostate implants...
  16. ncbi request reprint Dose rate constant of a cesium-131 interstitial brachytherapy seed measured by thermoluminescent dosimetry and gamma-ray spectrometry
    Z Chen
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06504, USA
    Med Phys 32:3279-85. 2005
    ..915 cGyh(-1)U(-1). Additional determinations of the dose rate constant may be needed to establish an AAPM recommended consensus value for routine clinical use of the 131Cs seed...
  17. pmc Photon energy spectrum emitted by a novel polymer-encapsulated 103Pd source and its effect on the dose rate constant
    Sabrina Khan
    Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Med Phys 35:1403-6. 2008
    ..668 cGy h(-1) U(-1) rather than 0.693 cGy h(-1) U(-1) as initially recommended by the source manufacturer based on the two previously published results...

Research Grants1

  1. Prostate Edema in Permanent Interstitial Brachytherapy
    Zhe Chen; Fiscal Year: 2010
    ..The primary objective of this project is to develop a new method to consider the effects of edema in radiation dosimetry and treatment planning so that the efficacy of this therapy can be optimized for each patient. ..