- IkappaB kinase epsilon interacts with p52 and promotes transactivation via p65Claudia Wietek
School of Biochemistry and Immunology, Trinity College, Dublin 2, Ireland
J Biol Chem 281:34973-81. 2006..These novel interactions reveal a hitherto unknown function of IKKepsilon in the regulation of the alternative NF-kappaB activation pathway involving p52 and p65...
- Diversity and regulation in the NF-kappaB systemClaudia Wietek
School of Biochemistry and Immunology, Trinity College Dublin, Dublin 2, Ireland
Trends Biochem Sci 32:311-9. 2007..Furthermore, the state of a cell and its cellular background in addition to overall promoter structure and variations in the kappaB target sequence will all define the composition and activity of multimeric NF-kappaB complexes...
- Interferon regulatory factor-3-mediated activation of the interferon-sensitive response element by Toll-like receptor (TLR) 4 but not TLR3 requires the p65 subunit of NF-kappaClaudia Wietek
Department of Biochemistry, Trinity College, Dublin, Ireland
J Biol Chem 278:50923-31. 2003..Finally, p65 promoted transactivation of gene expression by IRF-3. These results therefore indicate that IRF-3-mediated activation of the ISRE by TLR4 but not TLR3 requires the p65 subunit of NF-kappa B...