Musa T Yakubu

Summary

Publications

  1. pmc Effect of Aqueous Extract of Massularia acuminata Stem on Sexual Behaviour of Male Wistar Rats
    M T Yakubu
    Phytomedicine, Toxicology, Reproductive and Developmental Biochemistry Research Laboratory, Department of Biochemistry, University of Ilorin, PMB 1515, Ilorin, Nigeria
    Evid Based Complement Alternat Med 2011:738103. 2011
  2. pmc In vitro and in vivo antioxidant activities of the aqueous extract of Celosia argentea leaves
    S O Malomo
    Department of Biochemistry, University of Ilorin, Ilorin, Nigeria
    Indian J Pharmacol 43:278-85. 2011
  3. pmc Garcinia kola seeds: is the aqueous extract a true aphrodisiac in male Wistar rats?
    M T Yakubu
    Phytomedicine, Toxicology, Reproductive and Developmental Biochemistry Research Laboratory, Department of Biochemistry, University of Ilorin, PMB 1515, Ilorin, Nigeria
    Afr J Tradit Complement Altern Med 9:530-5. 2012
  4. doi request reprint Effects of aqueous extract of Musa paradisiaca root on testicular function parameters of male rats
    Musa Toyin Yakubu
    Department of Biochemistry, University of Ilorin, P M B 1515, Ilorin, Nigeria
    J Basic Clin Physiol Pharmacol 24:151-7. 2013
  5. doi request reprint Androgenic potentials of aqueous extract of Massularia acuminata (G. Don) Bullock ex Hoyl. stem in male Wistar rats
    Musa Toyin Yakubu
    Medicinal Plants Research Laboratory, Department of Biochemistry, University of Ilorin, PMB 1515, Ilorin, Nigeria
    J Ethnopharmacol 118:508-13. 2008
  6. doi request reprint Pro-sexual effects of aqueous extracts of Massularia acuminata root in male Wistar rats
    M T Yakubu
    Phytomedicine, Toxicology, Reproductive and Developmental Biochemistry Research Laboratory, Department of Biochemistry, University of Ilorin, Nigeria
    Andrologia 43:334-40. 2011
  7. doi request reprint Ananas comosus: is the unripe fruit juice an abortifacient in pregnant Wistar rats?
    Musa T Yakubu
    Phytomedicine, Toxicology, Reproductive and Developmental Biochemistry Research Laboratory, Department of Biochemistry, University of Ilorin, Nigeria
    Eur J Contracept Reprod Health Care 16:397-402. 2011
  8. ncbi request reprint Effects of oral administration of aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem on some testicular function indices of male rats
    Musa Toyin Yakubu
    Medicinal Plants Research Laboratory, Department of Biochemistry, University of Ilorin, P M B 1515 Ilorin, Nigeria
    J Ethnopharmacol 115:288-92. 2008
  9. ncbi request reprint Evaluation of antiandrogenic potentials of aqueous extract of Chromolaena odoratum (L.) K. R. leaves in male rats
    M T Yakubu
    Medicinal Plants Research Laboratory, Department of Biochemistry, University of Ilorin, Ilorin, Nigeria
    Andrologia 39:235-43. 2007
  10. doi request reprint Toxicological implications of aqueous extract of Bambusa vulgaris leaves in pregnant Dutch rabbits
    M T Yakubu
    Phytomedicine and Toxicology Research Laboratory, University of Ilorin, Ilorin, Nigeria
    Hum Exp Toxicol 28:591-8. 2009

Collaborators

  • A T Oladiji
  • Musa Salawu
  • Taofeek O Ajiboye
  • Musbau A Akanji
  • Joseph I Okogun
  • Quadri O Nurudeen
  • S O Malomo
  • Taofeek O Ajboye
  • Amadu K Salau
  • Joseph O Adebayo
  • Omoregie Nosarieme
  • Oghenetega T Oweh
  • A Ore
  • Nasir A Salawu
  • Victor B Owoyele
  • Evans C Egwim
  • Bernard U Enaibe

Detail Information

Publications25

  1. pmc Effect of Aqueous Extract of Massularia acuminata Stem on Sexual Behaviour of Male Wistar Rats
    M T Yakubu
    Phytomedicine, Toxicology, Reproductive and Developmental Biochemistry Research Laboratory, Department of Biochemistry, University of Ilorin, PMB 1515, Ilorin, Nigeria
    Evid Based Complement Alternat Med 2011:738103. 2011
    ....
  2. pmc In vitro and in vivo antioxidant activities of the aqueous extract of Celosia argentea leaves
    S O Malomo
    Department of Biochemistry, University of Ilorin, Ilorin, Nigeria
    Indian J Pharmacol 43:278-85. 2011
    ..w.) was investigated against cadmium (Cd)-induced oxidative stress in Wistar rats. The in vitro antioxidant of the extract was evaluated using ammonium thiocyanate, reducing power, and membrane stabilizing models...
  3. pmc Garcinia kola seeds: is the aqueous extract a true aphrodisiac in male Wistar rats?
    M T Yakubu
    Phytomedicine, Toxicology, Reproductive and Developmental Biochemistry Research Laboratory, Department of Biochemistry, University of Ilorin, PMB 1515, Ilorin, Nigeria
    Afr J Tradit Complement Altern Med 9:530-5. 2012
    ..This study has refuted the claim that one of the rationales for consuming the seeds by the aged population of Nigeria is to enhance sexual invigoration in males. ..
  4. doi request reprint Effects of aqueous extract of Musa paradisiaca root on testicular function parameters of male rats
    Musa Toyin Yakubu
    Department of Biochemistry, University of Ilorin, P M B 1515, Ilorin, Nigeria
    J Basic Clin Physiol Pharmacol 24:151-7. 2013
    ..paradisiaca root on the testes. Therefore, this study was aimed at investigating the effect of oral administration of the aqueous extract of M. paradisiaca root on the testicular function parameters of male rat testes...
  5. doi request reprint Androgenic potentials of aqueous extract of Massularia acuminata (G. Don) Bullock ex Hoyl. stem in male Wistar rats
    Musa Toyin Yakubu
    Medicinal Plants Research Laboratory, Department of Biochemistry, University of Ilorin, PMB 1515, Ilorin, Nigeria
    J Ethnopharmacol 118:508-13. 2008
    ..Aphrodisiac activity in some plants may be due to androgen increasing property of its phytochemicals...
  6. doi request reprint Pro-sexual effects of aqueous extracts of Massularia acuminata root in male Wistar rats
    M T Yakubu
    Phytomedicine, Toxicology, Reproductive and Developmental Biochemistry Research Laboratory, Department of Biochemistry, University of Ilorin, Nigeria
    Andrologia 43:334-40. 2011
    ..Therefore, the aqueous extract of M. acuminata roots at 50 and 100 mg kg(-1) body weight may be explored in the management of disorders of desire, premature ejaculation and erectile dysfunction in males...
  7. doi request reprint Ananas comosus: is the unripe fruit juice an abortifacient in pregnant Wistar rats?
    Musa T Yakubu
    Phytomedicine, Toxicology, Reproductive and Developmental Biochemistry Research Laboratory, Department of Biochemistry, University of Ilorin, Nigeria
    Eur J Contracept Reprod Health Care 16:397-402. 2011
    ..The juice of unripe pineapple (Ananas comosus) was investigated for abortifacient activity in pregnant Wistar rats...
  8. ncbi request reprint Effects of oral administration of aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem on some testicular function indices of male rats
    Musa Toyin Yakubu
    Medicinal Plants Research Laboratory, Department of Biochemistry, University of Ilorin, P M B 1515 Ilorin, Nigeria
    J Ethnopharmacol 115:288-92. 2008
    ..The effects of administration of aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem on some testicular function indices of male rats (Rattus norvegicus) and their recovery potentials for 10 days were investigated...
  9. ncbi request reprint Evaluation of antiandrogenic potentials of aqueous extract of Chromolaena odoratum (L.) K. R. leaves in male rats
    M T Yakubu
    Medicinal Plants Research Laboratory, Department of Biochemistry, University of Ilorin, Ilorin, Nigeria
    Andrologia 39:235-43. 2007
    ..odoratum leaves possesses antiandrogenic property by interfering with steroidogenesis at the testicular level and this will adversely affect the functional capacity of the testes and the fertility of the animal...
  10. doi request reprint Toxicological implications of aqueous extract of Bambusa vulgaris leaves in pregnant Dutch rabbits
    M T Yakubu
    Phytomedicine and Toxicology Research Laboratory, University of Ilorin, Ilorin, Nigeria
    Hum Exp Toxicol 28:591-8. 2009
    ..Therefore, the absence of histopathological lesions in the hepatocytes and nephrons implies that histopathological changes are not a sensitive assay for the assessment of tissue damage by the extract...
  11. doi request reprint Mode of cellular toxicity of aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem in male rat liver and kidney
    M T Yakubu
    Phytomedicine and Toxicology Research Laboratory, Department of Biochemistry, University of Ilorin, Ilorin, Nigeria
    Hum Exp Toxicol 28:469-78. 2009
    ..This may be responsible for the compromise of the integrity of the plasma membranes of the hepatocytes and nephrons...
  12. ncbi request reprint Aphrodisiac potentials of the aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem in male albino rats
    M T Yakubu
    Medicinal Plants Research Laboratory, Department of Biochemistry, University of Ilorin, PMB 1515, Ilorin, Nigeria
    Asian J Androl 7:399-404. 2005
    ..To evaluate the phytochemical constituents and the aphrodisiac potential of the aqueous extract of Fadogia agrestis (Rubiaceae) stem in male albino rats...
  13. doi request reprint Abortifacient potentials of the aqueous extract of Bambusa vulgaris leaves in pregnant Dutch rabbits
    Musa T Yakubu
    Department of Biochemistry, University of Ilorin, Ilorin, Nigeria
    Contraception 80:308-13. 2009
    ..There is the claim in the folklore medicine of Nigeria of the use of Bambusa vulgaris leaves as an abortifacient. However, there has not been any scientific evidence in the literature that substantiated or refuted this claim...
  14. doi request reprint Effect of a 60-day oral gavage of a crude alkaloid extract from Chromolaena odorata leaves on hormonal and spermatogenic indices of male rats
    Musa T Yakubu
    Departments of Respiratory Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    J Androl 33:1199-207. 2012
    ..This lack of testosterone may have consequential effects on the reproductive process of the male rat...
  15. doi request reprint Antioxidant and drug detoxification potentials of Hibiscus sabdariffa anthocyanin extract
    Taofeek O Ajiboye
    Phytomedicine and Toxicological Research Unit, Biochemistry Department, University of Ilorin, Nigeria
    Drug Chem Toxicol 34:109-15. 2011
    ..In view of these properties, Hibiscus sabdariffa anthocyanin extract can act as a prophylactic by intervening as a free radical scavenger both in vitro and in vivo as well as inducing the phase II drug detoxification enzymes...
  16. doi request reprint Antioxidant and drug detoxification potential of aqueous extract of Annona senegalensis leaves in carbon tetrachloride-induced hepatocellular damage
    Taofeek O Ajboye
    Phytomedicine, Toxicology, Reproductive and Developmental Biochemistry Research Laboratory, Department of Biochemistry, University of Ilorin, Nigeria
    Pharm Biol 48:1361-70. 2010
    ..Despite the myriad uses of Annona senegalensis Pers. (Annonaceae) leaves in folklore medicine of Nigeria, the basis is yet to be substantiated by scientific investigations...
  17. ncbi request reprint Effect of ethanolic extract of Khaya senegalensis on some biochemical parameters of rat kidney
    Joseph O Adebayo
    Department of Physiology and Biochemistry, Faculty of Health Sciences, University of Ilorin, Ilorin, Nigeria
    J Ethnopharmacol 88:69-72. 2003
    ....
  18. doi request reprint Acetaminophen perturbed redox homeostasis in Wistar rat liver: protective role of aqueous Pterocarpus osun leaf extract
    Taofeek O Ajiboye
    Phytomedicine and Toxicology Research Laboratory, Department of Biochemistry, University of Ilorin, Ilorin, Nigeria
    Drug Chem Toxicol 33:77-87. 2010
    ..The results indicates that P. osun leaves attenuated acetaminophen-induced redox imbalance, possibly acting as free radical scavenger, inducer of antioxidant and drug-detoxifying enzymes, which prevented/reduced lipid peroxidation...
  19. doi request reprint Lophirones B and C extenuate AFB1-mediated oxidative onslaught on cellular proteins, lipids, and DNA through Nrf-2 expression
    Taofeek O Ajiboye
    Antioxidants, Free Radicals, Functional Foods and Toxicology Research Laboratory, Department of Biological Sciences, Al Hikmah University, Ilorin, Nigeria
    J Biochem Mol Toxicol 28:558-67. 2014
    ..Results obtained showed that lophirones B and C extenuate AFB1-mediated onslaught on cellular proteins, lipids, and DNA by enhancing nuclear erythroid-related factor-2 expression...
  20. pdf Effect of Escherichia coli endotoxin on Archachatina marginata hemolymph coagulation system
    Musa O Salawu
    Department of Biochemistry, University of Ilorin, Ilorin, Nigeria
    Pharm Biol 49:1029-33. 2011
    ..The hemolymph is also used in traditional medicine practice. Investigation into its anti-endotoxin response is being studied for the first time...
  21. doi request reprint Cytotoxic, antimutagenic, and antioxidant activities of methanolic extract and chalcone dimers (lophirones B and C) derived from Lophira alata (Van Tiegh. Ex Keay) stem bark
    Taofeek O Ajiboye
    Al Hikmah University, Ilorin, Nigeria
    J Evid Based Complementary Altern Med 19:20-30. 2014
    ..The acclaimed anticancer activity of Lophira alata may be attributed to lophirones B and C. ..
  22. doi request reprint Electrophilic and reactive oxygen species detoxification potentials of chalcone dimers is mediated by redox transcription factor Nrf-2
    Taofeek O Ajiboye
    Antioxidants, Free Radicals, Functional Foods and Toxicology Research Laboratory, Department of Biological Sciences, Al Hikmah University, Ilorin, Nigeria
    J Biochem Mol Toxicol 28:11-22. 2014
    ..05). Overall, lophirones B and C increased the expressions and activities of cytoprotective proteins in rat liver possibly through the reduction of cytoplasmic Keap1 expression, leading to the nuclear translocation of Nrf2. ..
  23. doi request reprint Hemolymph coagulation and phenoloxidase activity in Uca tangeri induced by Escherichia coli endotoxin
    Musa O Salawu
    a Department of Biochemistry, University of Ilorin, Ilorin, Nigeria
    J Immunotoxicol 13:355-63. 2016
    ..From the data we conclude that endotoxin-induced protein coagulation occurs in the plasma alone and might be mediated by trans-glutaminases, while PO activity is localized inside hemocytes and cell membranes in Uca tangeri. ..
  24. doi request reprint Aqueous root extract of Lecaniodiscus cupanioides restores nitric oxide/cyclic guanosine monophosphate pathway in sexually impaired male rats
    Quadri O Nurudeen
    Phytomedicine, Toxicology and Reproductive Biochemistry Research Laboratory, Department of Biochemistry, University of Ilorin, Ilorin, Nigeria
    J Ethnopharmacol 175:181-4. 2015
    ..The effect of aqueous root extract of L. cupanioides root on the concentrations of penile cyclic Guanosine Monophosphate (cGMP) and plasma nitric oxide in paroxetine-induced sexually impaired male rats was evaluated...