Serbulent Yigit

Summary

Publications

  1. doi request reprint Investigation of CD40 gene rs4810485 and rs1883832 mutations in patients with recurrent aphthous stomatitis
    Serbulent Yigit
    Gaziosmanpasa University, Faculty of Medicine, Department of Medical Biology, Tokat, Turkey Electronic address
    Arch Oral Biol 74:51-54. 2017
  2. doi request reprint The effect of IL-4 and MTHFR gene variants in ankylosing spondylitis
    S Yigit
    Faculty of Medicine, Department of Medical Biology, Gaziosmanpasa University, Tokat, Turkey
    Z Rheumatol 74:60-6. 2015
  3. doi request reprint The role of IL-4 gene 70 bp VNTR and ACE gene I/D variants in Familial Mediterranean fever
    Serbulent Yigit
    Gaziosmanpasa University, Faculty of Medicine, Department of Medical Biology, Tokat, Turkey Electronic address
    Cytokine 67:1-6. 2014
  4. doi request reprint Association of angiotensin converting enzyme (ACE) gene I/D polymorphism and rheumatoid arthritis
    Serbulent Yigit
    Gaziosmanpasa University, Faculy of Medicine, Department of Medical Biology, Tokat, Turkey
    Gene 511:106-8. 2012
  5. doi request reprint DD genotype of ACE gene I/D polymorphism is associated with Behcet disease in a Turkish population
    Serbulent Yigit
    Department of Medical Biology, Faculty of Medicine, Gaziosmapaşa University, Tokat, Turkey
    Mol Biol Rep 40:365-8. 2013
  6. pmc Association between the methylene tetrahydrofolate reductase gene C677T mutation and colchicine unresponsiveness in Behcet's disease
    Nevin Karakus
    Ondokuz Mayis University, Faculty of Medicine, Department of Medical Biology, Samsun, Turkey
    Mol Vis 18:1696-700. 2012
  7. doi request reprint IL-4 and MTHFR gene polymorphism in rheumatoid arthritis and their effects
    Ahmet Inanir
    Department of Physical Therapy and Rehabilitation, Faculty of Medicine, Gaziosmanpasa University, Tokat, 60100, Turkey
    Immunol Lett 152:104-8. 2013
  8. doi request reprint The importance of association between angiotensin-converting enzyme (ACE) Gene I/D polymorphism and diabetic peripheral neuropathy
    Ahmet Inanir
    Gaziosmanpasa University, Faculty of Medicine, Department of Physical Therapy and Rehabilitation, Tokat, Turkey
    Gene 530:253-6. 2013
  9. pmc Association of IL-4 gene VNTR variant with deep venous thrombosis in Behçet's disease and its effect on ocular involvement
    Ahmet Inanir
    Gaziosmanpasa University, Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Tokat, Turkey
    Mol Vis 19:675-83. 2013
  10. doi request reprint Association between fibromyalgia syndrome and polymorphism of the IL-4 gene in a Turkish population
    Serbulent Yigit
    Gaziosmanpasa University, Faculty of Medicine, Department of Medical Biology, Tokat, Turkey
    Gene 527:62-4. 2013

Collaborators

Detail Information

Publications42

  1. doi request reprint Investigation of CD40 gene rs4810485 and rs1883832 mutations in patients with recurrent aphthous stomatitis
    Serbulent Yigit
    Gaziosmanpasa University, Faculty of Medicine, Department of Medical Biology, Tokat, Turkey Electronic address
    Arch Oral Biol 74:51-54. 2017
    ..RAS shows a large genetic diversity among the patients. In present study, we investigated whether CD40 gene rs4810485 and rs1883832 are associated with RAS and its clinical findings in Turkish patients...
  2. doi request reprint The effect of IL-4 and MTHFR gene variants in ankylosing spondylitis
    S Yigit
    Faculty of Medicine, Department of Medical Biology, Gaziosmanpasa University, Tokat, Turkey
    Z Rheumatol 74:60-6. 2015
    ....
  3. doi request reprint The role of IL-4 gene 70 bp VNTR and ACE gene I/D variants in Familial Mediterranean fever
    Serbulent Yigit
    Gaziosmanpasa University, Faculty of Medicine, Department of Medical Biology, Tokat, Turkey Electronic address
    Cytokine 67:1-6. 2014
    ..04). In addition IL-4 gene P1P1 genotype was associated with FMF (p<0.001). We propose that D allele or DD genotype of ACE gene and P1 allele or P1P1 genotype of IL-4 gene may be important molecular markers for susceptibility of FMF...
  4. doi request reprint Association of angiotensin converting enzyme (ACE) gene I/D polymorphism and rheumatoid arthritis
    Serbulent Yigit
    Gaziosmanpasa University, Faculy of Medicine, Department of Medical Biology, Tokat, Turkey
    Gene 511:106-8. 2012
    ..001). As a result of our study, angiotensin converting enzyme gene I/D polymorphism DD genotype could be a genetic marker in rheumatoid arthritis in the Turkish study population...
  5. doi request reprint DD genotype of ACE gene I/D polymorphism is associated with Behcet disease in a Turkish population
    Serbulent Yigit
    Department of Medical Biology, Faculty of Medicine, Gaziosmapaşa University, Tokat, Turkey
    Mol Biol Rep 40:365-8. 2013
    ..001). This study is the largest study in Turkish population that ACE gene I/D polymorphism investigated in BD. As a result of this study, ACE gene I/D polymorphism DD genotype could be a genetic marker in BD in Turkish study population...
  6. pmc Association between the methylene tetrahydrofolate reductase gene C677T mutation and colchicine unresponsiveness in Behcet's disease
    Nevin Karakus
    Ondokuz Mayis University, Faculty of Medicine, Department of Medical Biology, Samsun, Turkey
    Mol Vis 18:1696-700. 2012
    ..The aim of this study was to investigate the MTHFR gene C677 mutation in patients with BD and evaluate if there was an association with clinical features, especially thrombosis, in a relatively large cohort of patients with BD...
  7. doi request reprint IL-4 and MTHFR gene polymorphism in rheumatoid arthritis and their effects
    Ahmet Inanir
    Department of Physical Therapy and Rehabilitation, Faculty of Medicine, Gaziosmanpasa University, Tokat, 60100, Turkey
    Immunol Lett 152:104-8. 2013
    ..Our findings suggest that there is an association of IL-4 gene 70bp VNTR polymorphism and MTHFR C677T polymorphism with susceptibility of a person for development of RA. ..
  8. doi request reprint The importance of association between angiotensin-converting enzyme (ACE) Gene I/D polymorphism and diabetic peripheral neuropathy
    Ahmet Inanir
    Gaziosmanpasa University, Faculty of Medicine, Department of Physical Therapy and Rehabilitation, Tokat, Turkey
    Gene 530:253-6. 2013
    ..In the present study, it is aimed to evaluate angiotensin-converting enzyme (ACE) Gene I/D polymorphism in Turkish population...
  9. pmc Association of IL-4 gene VNTR variant with deep venous thrombosis in Behçet's disease and its effect on ocular involvement
    Ahmet Inanir
    Gaziosmanpasa University, Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Tokat, Turkey
    Mol Vis 19:675-83. 2013
    ..This study was conducted in Turkish patients with BD to determine the frequency of the IL-4 gene 70 bp variable number of tandem repeats (VNTR) variant, and its association with clinical findings...
  10. doi request reprint Association between fibromyalgia syndrome and polymorphism of the IL-4 gene in a Turkish population
    Serbulent Yigit
    Gaziosmanpasa University, Faculty of Medicine, Department of Medical Biology, Tokat, Turkey
    Gene 527:62-4. 2013
    ..The aim of this study was to investigate the interleukin-4 (IL-4) 70 bp VNTR variations in Turkish patients with FM and evaluate if there was an association with clinical features, especially between these polymorphisms...
  11. doi request reprint Association of interleukin (IL)-4 gene intron 3 VNTR polymorphism with multiple sclerosis in Turkish population
    Nevin Karakus
    Gaziosmanpasa University, Faculty of Medicine, Department of Medical Biology, Tokat, Turkey
    Hum Immunol 74:1157-60. 2013
    ..The aim of this study was to explore the frequency of IL-4 gene intron 3 VNTR (variable number tandem repeat) polymorphism in a cohort of Turkish patients with MS...
  12. doi request reprint Methylenetetrahydrofolate reductase C677T mutation in patients with alopecia areata in Turkish population
    Goknur Kalkan
    Gaziosmanpasa University, School of Medicine, Department of Dermatology, Tokat, Turkey Electronic address
    Gene 530:109-12. 2013
    ..Since there is a common shared pathway between AA and other autoimmune disorders, we aimed to investigate a possible association between the MTHFR gene C677T mutation and AA susceptibility in the Turkish population...
  13. doi request reprint Significance of MEFV gene R202Q polymorphism in Turkish familial Mediterranean fever patients
    Serbulent Yigit
    Gaziosmanpasa University, Faculty of Medicine, Department of Medical Biology, Tokat, Turkey
    Gene 506:43-5. 2012
    ..The aim of this study was to explore the frequency and clinical significance of the R202Q (c.605G>A) polymorphism in exon 2 of the MEFV gene in a cohort of Turkish patients with FMF...
  14. pmc Significant association between insertion/deletion polymorphism of the angiotensin-convertig enzyme gene and ankylosing spondylitis
    Ahmet Inanir
    Gaziosmanpasa University, Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Tokat, Turkey
    Mol Vis 18:2107-13. 2012
    ..This study was conducted in Turkish patients with AS to determine the frequency of I/D polymorphism genotypes of angiotensin converting enzyme gene...
  15. doi request reprint Significant association of interleukin-4 gene intron 3 VNTR polymorphism with susceptibility to knee osteoarthritis
    Serbulent Yigit
    Gaziosmanpasa University, Faculty of Medicine, Department of Medical Biology, Tokat, Turkey
    Gene 537:6-9. 2014
    ..We aimed to investigate genotype and allele frequencies of IL-4 gene intron 3 variable number of tandem repeats (VNTR) polymorphism in patients with knee OA in a Turkish population...
  16. doi request reprint Association between interleukin 4 gene intron 3 VNTR polymorphism and recurrent aphthous stomatitis in a cohort of Turkish patients
    Goknur Kalkan
    Gaziosmanpasa University, Faculty of Medicine, Department of Dermatovenerology, Tokat, Turkey
    Gene 527:207-10. 2013
    ..The purpose of the present study was to investigate a possible association between the functional interleukin 4 (IL4) VNTR genetic polymorphism and RAS in a sample of Turkish patients...
  17. doi request reprint Association of Genetic Polymorphisms in TNF and MIF Gene with the Risk of Primary Dysmenorrhea
    Hatice Yilmaz Dogru
    Department of Gynecology and Obstetrics, Medical Faculty, Gaziosmanpasa University, 60100, Tokat, Turkey
    Biochem Genet 54:457-66. 2016
    ..009). The present study showed that the TNF-α -308 GG genotype may be a useful tool to predict the susceptibility of dysmenorrhea. ..
  18. pmc Common Mediterranean fever (MEFV) gene mutations associated with ankylosing spondylitis in Turkish population
    Serbulent Yigit
    Department of Medical Biology, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey
    Dis Markers 33:113-8. 2012
    ..The results of this study suggest that MEFV gene mutations are positively associated with a predisposition to develop AS...
  19. pmc Association of MTHFR gene C677T mutation with diabetic peripheral neuropathy and diabetic retinopathy
    Serbulent Yigit
    Gaziosmanpasa University, Faculty of Medicine, Department of Medical Biology, Tokat, Turkey
    Mol Vis 19:1626-30. 2013
    ..The aim of the present study was to investigate the possible association between MTHFR gene C677T mutation and DPN and evaluate if there is an association with clinical features in a relatively large cohort of Turkish patients...
  20. doi request reprint The association between Interleukin (IL)-4 gene intron 3 VNTR polymorphism and alopecia areata (AA) in Turkish population
    Goknur Kalkan
    Gaziosmanpasa University, School of Medicine, Department of Dermatology, Tokat, Turkey
    Gene 527:565-9. 2013
    ....
  21. doi request reprint High association of IL-4 gene intron 3 VNTR polymorphism with diabetic peripheral neuropathy
    Nursah Basol
    Faculty of Medicine, Department of Emergency Medicine, Gaziosmanpasa University, 60100, Tokat, Turkey
    J Mol Neurosci 51:437-41. 2013
    ..00009). The results of this study suggested that intron 3 VNTR polymorphism of the IL-4 gene plays an important role in the occurrence of DPN in the Turkish population...
  22. doi request reprint Association of missense mutations of Mediterranean fever (MEFV) gene with multiple sclerosis in Turkish population
    Serbulent Yigit
    Department of Medical Biology, Faculty of Medicine, Gaziosmanpasa University, 60100 Tokat, Turkey
    J Mol Neurosci 50:275-9. 2013
    ..6, 95 % confidence interval (CI) 1.47-4.77 and p = 0.0002, OR 2.6, 95 % CI 1.55-4.48, respectively). The results of this study suggest that MEFV gene mutations are positively associated with predisposition to develop MS...
  23. pmc MTHFR gene C677T mutation and ACE gene I/D polymorphism in Turkish patients with osteoarthritis
    Ahmet Inanir
    Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey
    Dis Markers 34:17-22. 2013
    ..001, p< 0.001 respectively). Our study suggests that ACE gene DD genotype and MTHFR gene CC genotype could be used as genetic markers in osteoarthritis in Turkish study populations...
  24. doi request reprint Association analysis of three ABCB1 (MDR1) gene variants (C1236T, G2677A/T and C3435T) and their genotype/haplotype combinations with the familial Mediterranean fever
    Aydin Rüstemoğlu
    Department of Medical Biology, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey
    Xenobiotica 44:933-40. 2014
    ..0005, 0.002 and 0.000, respectively). 4. Our study showed that genotypes and haplotypes of ABCB1 gene polymorphisms may affect patients' FMF susceptibility...
  25. doi request reprint Angiotensin converting enzyme and methylenetetrahydrofolate reductase gene variations in fibromyalgia syndrome
    Ahmet Inanir
    Gaziosmanpasa University, Faculty of Medicine, Department of Physical Medicine and Rehabilitation, Tokat, Turkey Electronic address
    Gene 564:188-92. 2015
    ..The study aimed to determine the effects ACE I/D and MTHFR C677T gene polymorphisms in Turkish patients with FM and evaluate if there was an association with clinical features...
  26. doi request reprint The Evaluation of IL6 and ESR1 Gene Polymorphisms in Primary Dysmenorrhea
    Asker Zeki Özsoy
    a Department of Obstetrics and Gynecology, Gaziosmanpasa University, Faculty of Medicine, Tokat, Turkey
    Immunol Invest 45:75-86. 2016
    ..The potential association between ESR1 gene PvuII polymorphism and age and married status of dysmenorrhea patients deserves further consideration. ..
  27. doi request reprint High association of angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism with recurrent aphthous stomatitis
    Nevin Karakus
    Department of Medical Biology, Faculty of Medicine, Gaziosmanpasa University, 60100, Tokat, Turkey
    Arch Dermatol Res 305:513-7. 2013
    ..In conclusion, the results of this study suggest that I/D polymorphism of the ACE gene was positively associated with predisposition to develop RAS in Turkish population. Further studies with larger populations are recommended...
  28. doi request reprint Association of MEFV gene mutations with rheumatoid factor levels in patients with rheumatoid arthritis
    Ahmet Inanir
    Department of Physical Therapy and Rehabilitation, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey
    J Investig Med 61:593-6. 2013
    ..This gene has already been identified as being responsible for familial Mediterranean fever. The aim of this study was to explore the frequency and clinical significance of MEFV gene mutations in a cohort of Turkish patients with RA...
  29. pmc Investigation of associations between obesity and LEP G2548A and LEPR 668A/G polymorphisms in a Turkish population
    Server Sahın
    Department of Medical Biology, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey Department of Medical Biology, Faculty of Medicine, Tokat and Dumlupinar University, Kutahya, Turkey
    Dis Markers 35:673-7. 2013
    ..The aim of this study was to investigate the role of LEP G2548A and LEPR 668A/G polymorphisms in the pathogenesis of obesity...
  30. doi request reprint Association between MEFV gene mutations and recurrent aphthous stomatitis in a cohort of Turkish patients
    Goknur Kalkan
    Department of Dermatovenerology, Gaziosmanpasa University, Tokat, Turkey
    J Dermatol 40:516-21. 2013
    ..A statistically significant increased prevalence of MEFV variants in RAS patients was found. This is the first study to report that missense mutations of MEFV is associated with RAS in the Turkish population. ..
  31. ncbi request reprint The evaluation of angiotensin-converting enzyme (ACE) gene I/D and IL-4 gene intron 3 VNTR polymorphisms in coronary artery disease
    Nursah Basol
    Gaziosmanpasa University, Faculty of Medicine, Department of Emergency Medicine, Tokat, Turkey
    In Vivo 28:983-7. 2014
    ..In the present study, our aim was to evaluate angiotensin-converting enzyme (ACE) gene I/D polymorphism and interleukin-4 (IL-4) gene Intron 3 variable number of tandem repeat (VNTR) polymorphism in CAD...
  32. doi request reprint Association between sequence variations of the Mediterranean fever gene and fibromyalgia syndrome in a cohort of Turkish patients
    Nevin Karakus
    Faculty of Medicine, Department of Medical Biology, Ondokuz Mayis University, Samsun, Turkey
    Clin Chim Acta 414:36-40. 2012
    ..The aim of this study was to explore the frequency and clinical significance of missense mutations and a common polymorphism of MEFV gene in a cohort of Turkish patients with FMS...
  33. ncbi request reprint Lack of association between MIF gene -173G>C polymorphism with multiple sclerosis
    Betul Cevik
    Gaziosmanpasa University Faculty of Medicine, Department of Neurology, Tokat, Turkey
    In Vivo 29:71-6. 2015
    ..The aim of the present study was to investigate a possible association between the MIF -173G>C polymorphism and MS in Turkish patients...
  34. pmc Evaluation of MIF -173 G/C Polymorphism in Turkish Patients with Ankylosing Spondylitis
    Çevik Gürel
    Department of Medical Biology, Gaziosmanpasa University School of Medicine, Tokat, Turkey
    Balkan Med J 33:614-619. 2016
    ..Macrophage migration inhibitory (MIF) factor is a regulatory cytokine that inhibits random immune cell migration. MIF gene promoter polymorphisms play a role in the progression of several inflammatory disorders...
  35. doi request reprint Associations of rs4810485 and rs1883832 polymorphisms of CD40 gene with susceptibility and clinical findings of Behçet's disease
    Esra Erkol Inal
    Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Suleyman Demirel University, Isparta, Turkey
    Rheumatol Int 35:837-43. 2015
    ..We suggest that differences in the expression levels of CD40 because of different genotypes of these two SNPs may take part in the development of skin lesions or genital ulcers in patients with BD...
  36. doi request reprint Association of methylenetetrahydrofolate reductase gene C677T polymorphism with multiple sclerosis in Turkish patients
    Betul Cevik
    From the Departments of Neurology and Medical Biology, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey
    J Investig Med 62:980-4. 2014
    ..The aim of this study was to investigate a possible association between the MTHFR gene C677T polymorphism and MS in Turkish patients...
  37. doi request reprint Effects of interleukin (IL)-6 gene polymorphisms on recurrent aphthous stomatitis
    Nevin Karakus
    Department of Medical Biology, Faculty of Medicine, Gaziosmanpasa University, 60100, Tokat, Turkey
    Arch Dermatol Res 306:173-80. 2014
    ..011). Susceptibility effects of both IL-6 gene -572G>C and -174G>C polymorphisms for RAS were observed. Further studies are necessary to prove the association of IL-6 gene polymorphisms with RAS...
  38. doi request reprint Association of MTHFR gene C677T mutation with recurrent aphthous stomatitis and number of oral ulcers
    Goknur Kalkan
    Faculty of Medicine, Department of Dermatology, Gaziosmanpasa University, 60100, Tokat, Turkey
    Clin Oral Investig 18:437-41. 2014
    ..The aim of the present study was to investigate the possible association between MTHFR gene C677T mutation and RAS and evaluate if there was an association with clinical features in a relatively large cohort of Turkish patients...
  39. doi request reprint MDR1 gene polymorphisms may be associated with Behçet's disease and its colchicum treatment response
    Aydin Rüstemoğlu
    Gaziosmanpasa University, Medical Faculty, Department of Medical Biology, 60100, Tokat, Turkey
    Gene 505:333-9. 2012
    ..86-23.30) and T allele (p=0.009; OR, 2.09; 95% CI, 1.18-3.70) plays a substantial role in the colchicine response. Our study showed that MDR1 genes and their polymorphisms may affect a patient's BD susceptibility and colchicine response...
  40. doi request reprint Interleukin-1Ra rs2234663 and Interleukin-4 rs79071878 Polymorphisms in Familial Mediterranean Fever
    Ayşe Feyda Nursal
    Giresun University, Faculty of Medicine, Department of Medical Genetic, Giresun, Turkey
    Gene 582:173-7. 2016
    ..The aim of this study was to investigate the relationship of interleukin-1 receptor antagonist (IL-1Ra) and interleukin-4 (IL-4) polymorphisms with the risk of FMF in the Turkish population...
  41. doi request reprint The importance of MTHFR C677T/A1298C combined polymorphisms in pulmonary embolism in Turkish population
    Nursah Basol
    Department of Emergency Medicine, Faculty of Medicine, Gaziosmanpasa University, Tokat, Turkey Electronic address
    Medicina (Kaunas) 52:35-40. 2016
    ..In the present study, the aim was to evaluate MTHFR C677T and A1298C polymorphisms that play a role on folate metabolism in PE patients...
  42. ncbi request reprint MEFV mutations in patients with familial Mediterranean fever in the Black Sea region of Turkey: Samsun experience [corrected]
    Serbulent Yigit
    Department of Medical Biology, Ondokuz Mayis University, Samsun, Turkey
    J Rheumatol 35:106-13. 2008
    ....