Gene Symbol: BBOV_II000780
Description: dihydrofolate reductase/thymidilate synthase
Species: Babesia bovis T2Bo
- Inhibitor-bound complexes of dihydrofolate reductase-thymidylate synthase from Babesia bovisDarren W Begley
Seattle Structural Genomics Center for Infectious Disease http www ssgcid org, USA
Acta Crystallogr Sect F Struct Biol Cryst Commun 67:1070-7. 2011..The complexes reveal modes of binding similar to that seen in drug-resistant malaria strains and point to the utility of applying structural studies with proven cancer chemotherapies towards infectious disease research...