CEBPB

Summary

Gene Symbol: CEBPB
Description: CCAAT/enhancer binding protein beta
Alias: NF-M, CCAAT/enhancer-binding protein beta, CCAAT box/enhancer binding protein beta, CCAAT/enhancer binding protein (C/EBP), beta, CCR protein, c/EBP beta, transcription factor NF-M
Species: chicken

Top Publications

  1. pmc Synergistic activation of the chicken mim-1 gene by v-myb and C/EBP transcription factors
    O Burk
    Hans Spemann Laboratory, Max Planck Institute for Immunobiology, Freiburg, Germany
    EMBO J 12:2027-38. 1993
  2. pmc C/EBPbeta (NF-M) is essential for activation of the p20K lipocalin gene in growth-arrested chicken embryo fibroblasts
    S Kim
    Department of Biology, York University, Toronto, Ontario, Canada M3J 1P3
    Mol Cell Biol 19:5718-31. 1999
  3. pmc Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code
    Elisabeth Kowenz-Leutz
    Max Delbrueck Center for Molecular Medicine, Berlin, Germany
    EMBO J 29:1105-15. 2010
  4. doi Expression profiles of key transcription factors involved in lipid metabolism in Beijing-You chickens
    R Q Fu
    Institute of Animal Sciences IAS, Chinese Academy of Agricultural Sciences CAAS, Beijing 100193, China State Key Laboratory of Animal Nutrition, Beijing 100193, China Key Laboratory of Farm Animal Genetic Resources and Germplasm Innovation, Ministry of Agriculture, Beijing 100193, China
    Gene 537:120-5. 2014
  5. pmc The NF-M transcription factor is related to C/EBP beta and plays a role in signal transduction, differentiation and leukemogenesis of avian myelomonocytic cells
    S Katz
    Zentrum fur Molekulare Biologie, Universitat Heidelberg, Germany
    EMBO J 12:1321-32. 1993
  6. ncbi Identification of a Myb-responsive enhancer of the chicken C/EBPbeta gene
    Jörg Kintscher
    Institut fur Biochemie, Westfalische Wilhelms Universitat Munster, Wilhelm Klemm Str 2, D 48149 Munster, Germany
    Oncogene 23:5807-14. 2004
  7. ncbi Regulation of C/EBPbeta mRNA expression and C/EBPbeta promoter activity by protein kinases A and C in a myelomonocytic cell line (HD11)
    R Goethe
    Institute for Microbiology, Department of Infectious Diseases, University of Veterinary Medicine, Bischofsholer Damm 15, 30173 Hannover, Germany
    Inflamm Res 56:274-81. 2007
  8. pmc C/EBPbeta induces chromatin opening at a cell-type-specific enhancer
    Annette Plachetka
    Institut fur Biochemie, Westfalische Wilhelms Universitat Munster, Wilhelm Klemm Str 2, D 48149 Munster, Germany
    Mol Cell Biol 28:2102-12. 2008
  9. doi v-Myc inhibits C/EBPbeta activity by preventing C/EBPbeta-induced phosphorylation of the co-activator p300
    S Steinmann
    Institut fur Biochemie, Westfalische Wilhelms Universitat Munster, Munster, Germany
    Oncogene 28:2446-55. 2009

Detail Information

Publications9

  1. pmc Synergistic activation of the chicken mim-1 gene by v-myb and C/EBP transcription factors
    O Burk
    Hans Spemann Laboratory, Max Planck Institute for Immunobiology, Freiburg, Germany
    EMBO J 12:2027-38. 1993
    ..Our results suggest a role for C/EBP beta, and possibly for other C/EBP transcription factors, in v-myb function and in myeloid-specific gene activation...
  2. pmc C/EBPbeta (NF-M) is essential for activation of the p20K lipocalin gene in growth-arrested chicken embryo fibroblasts
    S Kim
    Department of Biology, York University, Toronto, Ontario, Canada M3J 1P3
    Mol Cell Biol 19:5718-31. 1999
    ..Therefore, we have identified C/EBPbeta as a key activator of a growth arrest-specific gene in CEF and implicated an essential fatty acid, linoleic acid, in regulation of the QRU and the p20K lipocalin gene...
  3. pmc Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor code
    Elisabeth Kowenz-Leutz
    Max Delbrueck Center for Molecular Medicine, Berlin, Germany
    EMBO J 29:1105-15. 2010
    ..Thus, phosphorylation of the transcription factor C/EBPbeta couples ras signalling to arginine methylation and regulates the interaction of C/EBPbeta with epigenetic gene regulatory protein complexes during cell differentiation...
  4. doi Expression profiles of key transcription factors involved in lipid metabolism in Beijing-You chickens
    R Q Fu
    Institute of Animal Sciences IAS, Chinese Academy of Agricultural Sciences CAAS, Beijing 100193, China State Key Laboratory of Animal Nutrition, Beijing 100193, China Key Laboratory of Farm Animal Genetic Resources and Germplasm Innovation, Ministry of Agriculture, Beijing 100193, China
    Gene 537:120-5. 2014
    ..Taken together, all five transcription factors studied play roles in lipid metabolism in chickens with C/EBPα and PPARγ being important effectors...
  5. pmc The NF-M transcription factor is related to C/EBP beta and plays a role in signal transduction, differentiation and leukemogenesis of avian myelomonocytic cells
    S Katz
    Zentrum fur Molekulare Biologie, Universitat Heidelberg, Germany
    EMBO J 12:1321-32. 1993
    ..Our data indicate that NF-M plays a key role in myelomonocytic differentiation, in signal transduction during macrophage activation and in the development of myelogenous leukemia...
  6. ncbi Identification of a Myb-responsive enhancer of the chicken C/EBPbeta gene
    Jörg Kintscher
    Institut fur Biochemie, Westfalische Wilhelms Universitat Munster, Wilhelm Klemm Str 2, D 48149 Munster, Germany
    Oncogene 23:5807-14. 2004
    ..Apart from the identification of a novel Myb-dependent enhancer, our work demonstrates the potential of chromatin structure analysis for the identification of Myb target sites...
  7. ncbi Regulation of C/EBPbeta mRNA expression and C/EBPbeta promoter activity by protein kinases A and C in a myelomonocytic cell line (HD11)
    R Goethe
    Institute for Microbiology, Department of Infectious Diseases, University of Veterinary Medicine, Bischofsholer Damm 15, 30173 Hannover, Germany
    Inflamm Res 56:274-81. 2007
    ..In this study, signal transduction pathways regulating C/EBPbeta expression were investigated...
  8. pmc C/EBPbeta induces chromatin opening at a cell-type-specific enhancer
    Annette Plachetka
    Institut fur Biochemie, Westfalische Wilhelms Universitat Munster, Wilhelm Klemm Str 2, D 48149 Munster, Germany
    Mol Cell Biol 28:2102-12. 2008
    ..Our work identifies a novel function for C/EBPbeta in the initial steps of a localized chromatin opening at a specific, physiologically relevant target region...
  9. doi v-Myc inhibits C/EBPbeta activity by preventing C/EBPbeta-induced phosphorylation of the co-activator p300
    S Steinmann
    Institut fur Biochemie, Westfalische Wilhelms Universitat Munster, Munster, Germany
    Oncogene 28:2446-55. 2009
    ..Overall, our findings that the modulation of the C/EBPbeta-induced phosphorylation of p300 as a new mechanism of transcriptional suppression by v-Myc...