LCN8

Summary

Gene Symbol: LCN8
Description: lipocalin 8
Alias: EX-FABP, EXFABP, P20K, extracellular fatty acid binding protein, extracellular fatty acid-binding protein, quiescence-specific protein
Species: chicken

Top Publications

  1. doi Polymorphisms in chicken extracellular fatty acid binding protein gene
    Zhi Yuan Zhao
    Agricultural College, Guangdong Ocean University, Zhanjiang 524088, People s Republic of China
    Mol Biol Rep 39:2677-82. 2012
  2. ncbi Acute phase lipocalin Ex-FABP is involved in heart development and cell survival
    C Gentili
    Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy
    J Cell Physiol 202:683-9. 2005
  3. ncbi Differentiation-dependent activation of the extracellular fatty acid binding protein (Ex-FABP) gene during chondrogenesis
    Paolo Giannoni
    Istituto Nazionale per la Ricerca sul Cancro, Largo Rosanna Benzi, Genoa, Italy
    J Cell Physiol 198:144-54. 2004
  4. ncbi Inhibition of cell proliferation and induction of apoptosis by ExFABP gene targeting
    Eddi Di Marco
    Istituto Nazionale per la Ricerca sul Cancro, Centro Biotecnologie Avanzate, Genova, Italy
    J Cell Physiol 196:464-73. 2003
  5. ncbi Ex-FABP, extracellular fatty acid binding protein, is a stress lipocalin expressed during chicken embryo development
    Fiorella Descalzi Cancedda
    Istituto Nazionale per la Ricerca sul Cancro, Centro Biotecnologie Avanzate, Genova, Italy
    Mol Cell Biochem 239:221-5. 2002
  6. ncbi Ex-FABP: a fatty acid binding lipocalin developmentally regulated in chicken endochondral bone formation and myogenesis
    F Descalzi Cancedda
    Istituto Nazionale per la Ricerca sul Cancro, Centro di Biotecnologie Avanzate, Largo Rosanna Benzi, Genoa, Italy
    Biochim Biophys Acta 1482:127-35. 2000
  7. ncbi Extracellular fatty acid binding protein (Ex-FABP) modulation by inflammatory agents: "physiological" acute phase response in endochondral bone formation
    S Cermelli
    Istituto Nazionale per la Ricerca sul Cancro, Centro di Biotecnologie Avanzate, Genova Italy
    Eur J Cell Biol 79:155-64. 2000
  8. ncbi Expression of the extracellular fatty acid binding protein (Ex-FABP) during muscle fiber formation in vivo and in vitro
    C Gentili
    Istituto Nazionale per la Ricerca sul Cancro, Centro di Biotecnologie Avanzate, Genoa, Italy
    Exp Cell Res 242:410-8. 1998
  9. ncbi The developmentally regulated avian Ch21 lipocalin is an extracellular fatty acid-binding protein
    F D Cancedda
    Centro di Biotecnologie Avanzate, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy
    J Biol Chem 271:20163-9. 1996
  10. pmc Rapid repression of quiescence-specific gene expression by epidermal growth factor, insulin, and pp60v-src
    P A Bedard
    Department of Cellular and Developmental Biology, Harvard University, Cambridge, Massachusetts 02138
    Mol Cell Biol 9:1371-5. 1989

Scientific Experts

  • C Gentili
  • Paolo Giannoni
  • Ranieri Cancedda
  • Zhi Yuan Zhao
  • Fiorella Descalzi Cancedda
  • S Cermelli
  • Eddi Di Marco
  • Barbara Zerega
  • F D Cancedda
  • Bing Wang Du
  • Wei Wei Wu
  • Xin Sheng Jiang
  • Wen Xia Tian
  • F Descalzi Cancedda
  • Li Zhang
  • Chang Hui Ye
  • Shu Jun Li
  • Ning Xian Cao
  • B Zerega
  • M Carlevaro
  • B Dozin
  • Nadia Sessarego
  • Beatrice Dozin
  • Silvia Cermelli
  • C Farquharson
  • B Thorp
  • P Bet
  • M Malpeli
  • V Di Marzo
  • T Nakano
  • M Hayashi
  • F Molina
  • F Descalzi
  • A Negri
  • L Briata
  • S Ronchi
  • P A Bedard
  • R Quarto
  • K Hayashi
  • T Graf
  • Y Yannoni
  • D Asaro
  • C Caruso
  • F Rossi
  • R L Erikson
  • D L Simmons
  • L Camardella

Detail Information

Publications14

  1. doi Polymorphisms in chicken extracellular fatty acid binding protein gene
    Zhi Yuan Zhao
    Agricultural College, Guangdong Ocean University, Zhanjiang 524088, People s Republic of China
    Mol Biol Rep 39:2677-82. 2012
    In this study, we report the investigation of extracellular fatty acid binding protein gene (Ex-FABP) genetic polymorphism in a sample of 360 chicken individuals...
  2. ncbi Acute phase lipocalin Ex-FABP is involved in heart development and cell survival
    C Gentili
    Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy
    J Cell Physiol 202:683-9. 2005
    Ex-FABP is an extracellular fatty acid binding protein, expressed during chicken embryo development in cartilage, muscle fibers, and blood granulocytes...
  3. ncbi Differentiation-dependent activation of the extracellular fatty acid binding protein (Ex-FABP) gene during chondrogenesis
    Paolo Giannoni
    Istituto Nazionale per la Ricerca sul Cancro, Largo Rosanna Benzi, Genoa, Italy
    J Cell Physiol 198:144-54. 2004
    Chicken hypertrophic chondrocytes secrete the extracellular fatty acid binding protein (Ex-FABP), a lipocalin not expressed by their undifferentiated precursors...
  4. ncbi Inhibition of cell proliferation and induction of apoptosis by ExFABP gene targeting
    Eddi Di Marco
    Istituto Nazionale per la Ricerca sul Cancro, Centro Biotecnologie Avanzate, Genova, Italy
    J Cell Physiol 196:464-73. 2003
    ..We suggest that Ex-FABP acts as a constitutive survival protein and that its expression and activation are fundamental to protect chondrocytes from cell death...
  5. ncbi Ex-FABP, extracellular fatty acid binding protein, is a stress lipocalin expressed during chicken embryo development
    Fiorella Descalzi Cancedda
    Istituto Nazionale per la Ricerca sul Cancro, Centro Biotecnologie Avanzate, Genova, Italy
    Mol Cell Biochem 239:221-5. 2002
    b>Extracellular Fatty Acid Binding Protein (Ex-FABP) is a 21 kDa lipocalin, expressed during chicken embryo development in hypertrophic cartilage, in muscle fibres and in blood granulocyte...
  6. ncbi Ex-FABP: a fatty acid binding lipocalin developmentally regulated in chicken endochondral bone formation and myogenesis
    F Descalzi Cancedda
    Istituto Nazionale per la Ricerca sul Cancro, Centro di Biotecnologie Avanzate, Largo Rosanna Benzi, Genoa, Italy
    Biochim Biophys Acta 1482:127-35. 2000
    b>Extracellular fatty acid binding protein (Ex-FABP) is a 21 kDa lipocalin specifically binding fatty acids, expressed during chicken embryo development in hypertrophic cartilage, in muscle fibers and in blood granulocytes...
  7. ncbi Extracellular fatty acid binding protein (Ex-FABP) modulation by inflammatory agents: "physiological" acute phase response in endochondral bone formation
    S Cermelli
    Istituto Nazionale per la Ricerca sul Cancro, Centro di Biotecnologie Avanzate, Genova Italy
    Eur J Cell Biol 79:155-64. 2000
    Ex-FABP, extracellular fatty acid binding protein, is a 21 kDa lipocalin expressed in hypertrophic cartilage, muscle and heart during chick embryo development and in granulocytes...
  8. ncbi Expression of the extracellular fatty acid binding protein (Ex-FABP) during muscle fiber formation in vivo and in vitro
    C Gentili
    Istituto Nazionale per la Ricerca sul Cancro, Centro di Biotecnologie Avanzate, Genoa, Italy
    Exp Cell Res 242:410-8. 1998
    ....
  9. ncbi The developmentally regulated avian Ch21 lipocalin is an extracellular fatty acid-binding protein
    F D Cancedda
    Centro di Biotecnologie Avanzate, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy
    J Biol Chem 271:20163-9. 1996
    ..We propose to rename the Ch21 protein as extracellular fatty acid-binding protein (Ex-FABP)...
  10. pmc Rapid repression of quiescence-specific gene expression by epidermal growth factor, insulin, and pp60v-src
    P A Bedard
    Department of Cellular and Developmental Biology, Harvard University, Cambridge, Massachusetts 02138
    Mol Cell Biol 9:1371-5. 1989
    We isolated a cDNA for p20K, a secreted protein preferentially synthesized in nonproliferating cells. p20K mRNA and protein levels declined rapidly following treatment with various mitogens...
  11. ncbi The amino terminal sequence of the developmentally regulated Ch21 protein shows homology with amino terminal sequences of low molecular weight proteins binding hydrophobic molecules
    F Descalzi Cancedda
    Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
    Biochem Biophys Res Commun 168:933-8. 1990
    ..Determination of the amino terminal sequence of the chicken retinol binding protein excluded identity between this protein and the Ch21...
  12. ncbi The Ch21 protein, developmentally regulated in chick embryo, belongs to the superfamily of lipophilic molecule carrier proteins
    F D Cancedda
    Laboratorio Differenziamento Cellulare, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy
    J Biol Chem 265:19060-4. 1990
    ..065 kDa. Computer-assisted analysis showed that the Ch21 belongs to the superfamily of low molecular weight proteins sharing a basic framework for binding and transport of small hydrophobic molecules...
  13. ncbi Expression, regulation, and tissue distribution of the Ch21 protein during chicken embryogenesis
    B Dozin
    Laboratorio Differenziamento Cellulare, Istituto Nazionale per la Ricerca sul Cancro, Genova, Italy
    J Biol Chem 267:2979-85. 1992
    ..Thus quiescence per se is not the primary factor determining the expression of the protein...
  14. ncbi Identification of genes differentially expressed in two types of v-myb-transformed avian myelomonocytic cells
    T Nakano
    Differentiation Programme, European Molecular Biology Laboratory, Heidelberg, Germany
    Oncogene 7:527-34. 1992
    ..The others were found to encode a small calcium-binding (MRP-like) protein; the p20K protein; goose-type lysozyme; a ribonuclease A/angiogenin-related protein; and three non-identified proteins...