BOLA-DQA1

Summary

Gene Symbol: BOLA-DQA1
Description: major histocompatibility complex, class II, DQ alpha, type 1
Alias: BoLA-DQA, major histocompatibility complex, class II, DQ alpha, type 1, MHC class II antigen
Species: cow

Top Publications

  1. ncbi Cattle cDNA clone encoding a new allele of the MHC class II DQA1 gene
    Y Nishino
    Laboratory of Gene Technology and Safety, Tsukuba Life Science Center, Institute of Physical and Chemical Research RIKEN, Ibaraki, Japan
    Immunogenetics 42:306-7. 1995
  2. ncbi Sequencing and genetic analysis of a bovine DQA cDNA clone
    A Xu
    Department of Animal Sciences, University of Illinois, Urbana 61801
    Immunogenetics 37:231-4. 1993
  3. ncbi Characterization of cattle cDNA sequences from two DQA loci
    G C Russell
    Roslin Institute, Roslin, Midlothian EH25 9PS, United Kingdom
    Immunogenetics 45:455-8. 1997
  4. ncbi Intrahaplotype and interhaplotype pairing of bovine leukocyte antigen DQA and DQB molecules generate functional DQ molecules important for priming CD4(+) T-lymphocyte responses
    Junzo Norimine
    Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164 7040, USA
    Immunogenetics 57:750-62. 2005
  5. ncbi Establishment of a sequence-based typing system for BoLA-DQA1 exon 2
    S Takeshima
    Retrovirus Research Unit, RIKEN, Saitama, Japan
    Tissue Antigens 69:189-99. 2007
  6. doi Evidence for cattle major histocompatibility complex (BoLA) class II DQA1 gene heterozygote advantage against clinical mastitis caused by Streptococci and Escherichia species
    S Takeshima
    Viral Infectious Diseases Unit, RIKEN, Saitama, Japan
    Tissue Antigens 72:525-31. 2008
  7. doi Association of BoLA DRB3 and DQA1 alleles with susceptibility to Neospora caninum and reproductive outcome in Quebec Holstein cattle
    Anne E Schwab
    Departement des Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, St Hyacinthe, Quebec, Canada
    Vet Parasitol 165:136-40. 2009

Scientific Experts

  • S Takeshima
  • Y Aida
  • Anne E Schwab
  • Junzo Norimine
  • Andreas J Schwab
  • Gilles Fecteau
  • Paul Baillargeon
  • Timothy G Geary
  • H Mukoyama
  • J Chen
  • T Yoshida
  • Y Matsumoto
  • A Miki
  • M Kado
  • Wendy C Brown
  • G C Russell
  • Y Nishino
  • A Gallagher
  • S Craigmile
  • E J Glass
  • A Xu
  • S Tajima
  • H A Lewin
  • K McKenna

Detail Information

Publications7

  1. ncbi Cattle cDNA clone encoding a new allele of the MHC class II DQA1 gene
    Y Nishino
    Laboratory of Gene Technology and Safety, Tsukuba Life Science Center, Institute of Physical and Chemical Research RIKEN, Ibaraki, Japan
    Immunogenetics 42:306-7. 1995
  2. ncbi Sequencing and genetic analysis of a bovine DQA cDNA clone
    A Xu
    Department of Animal Sciences, University of Illinois, Urbana 61801
    Immunogenetics 37:231-4. 1993
  3. ncbi Characterization of cattle cDNA sequences from two DQA loci
    G C Russell
    Roslin Institute, Roslin, Midlothian EH25 9PS, United Kingdom
    Immunogenetics 45:455-8. 1997
  4. ncbi Intrahaplotype and interhaplotype pairing of bovine leukocyte antigen DQA and DQB molecules generate functional DQ molecules important for priming CD4(+) T-lymphocyte responses
    Junzo Norimine
    Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164 7040, USA
    Immunogenetics 57:750-62. 2005
    ..Functional BoLA-DQ molecules are generated by both intrahaplotype and interhaplotype pairing of A and B chains and play a similar role to BoLA-DR in priming helper T-cell responses to important pathogens...
  5. ncbi Establishment of a sequence-based typing system for BoLA-DQA1 exon 2
    S Takeshima
    Retrovirus Research Unit, RIKEN, Saitama, Japan
    Tissue Antigens 69:189-99. 2007
    ..Together with the previously developed method for typing BoLA-DRB3, the PCR-SBT for BoLA-DQA1 clearly provides a useful tool for detailed class IIa haplotype analysis...
  6. doi Evidence for cattle major histocompatibility complex (BoLA) class II DQA1 gene heterozygote advantage against clinical mastitis caused by Streptococci and Escherichia species
    S Takeshima
    Viral Infectious Diseases Unit, RIKEN, Saitama, Japan
    Tissue Antigens 72:525-31. 2008
    ..This is the first report showing that heterozygosity of the BoLA-DQA1 gene is associated with resistance to mastitis progression...
  7. doi Association of BoLA DRB3 and DQA1 alleles with susceptibility to Neospora caninum and reproductive outcome in Quebec Holstein cattle
    Anne E Schwab
    Departement des Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, St Hyacinthe, Quebec, Canada
    Vet Parasitol 165:136-40. 2009
    ..caninum. However, an association of allele DRB3*1001 and allele DRB3*2703 with resistance and susceptibility to pregnancy loss, irrespective of infection status, was identified...