DQB

Summary

Gene Symbol: DQB
Description: MHC class II antigen
Alias: BoLA-DQB, BoLA-DQB1, DQB, DQB1, OLA-DQB, boLa class II histocompatibility antigen, DQB*0101 beta chain, DQB1*1A, MHC class II OLA-DQ-alpha, boLA-DQB, major histocompatibility complex antigen class II, major histocompatibility complex class II
Species: cow

Top Publications

  1. ncbi Nucleotide sequence of the second exon of a BoLA-DQB gene
    R T Stone
    US Meat Animal Research Center, Clay Center, Nebraska 68933 0166
    Anim Genet 23:273-4. 1992
  2. ncbi Gene duplications and sequence polymorphism of bovine class II DQB genes
    S Sigurdardottir
    Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala
    Immunogenetics 35:205-13. 1992
  3. ncbi Sequencing and genetic analysis of a bovine DQB cDNA clone
    A Xu
    Department of Animal Sciences, University of Illinois, Urbana Champaign
    Anim Genet 22:381-98. 1991
  4. ncbi The specificity of anti-HLA class II monoclonal antibodies in cattle
    P R Nilsson
    Department of Animal Husbandry, Agricultural University, Wageningen, The Netherlands
    Eur J Immunogenet 24:211-23. 1997
  5. ncbi Sequence duplication at the 3' end of BoLA-DQB genes suggests multiple allelic lineages
    G C Russell
    Department of Genomics and Bioinformatics, Roslin Institute, Midlothian, UK
    Immunogenetics 52:101-6. 2000
  6. ncbi Identification of 19 new BoLA-DQB alleles
    K Wang
    Department of Animal Genetics and Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100094, China
    Anim Genet 36:166-7. 2005
  7. ncbi Intrahaplotype and interhaplotype pairing of bovine leukocyte antigen DQA and DQB molecules generate functional DQ molecules important for priming CD4(+) T-lymphocyte responses
    Junzo Norimine
    Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164 7040, USA
    Immunogenetics 57:750-62. 2005

Scientific Experts

  • George C Russell
  • K Wang
  • Junzo Norimine
  • Wendy C Brown
  • R Xu
  • D Sun
  • Y Zhang
  • P R Nilsson
  • M G Nieuwland
  • E J Hensen
  • S Mikko
  • M C Grosfeld-Stulemeyer
  • I Joosten
  • S G Marsh
  • A Gelhaus
  • G M Schreuder
  • R T Stone
  • S Sigurdardottir
  • C Borsch
  • K Gustafsson
  • A Xu
  • L Andersson
  • N E Muggli-Cockett
  • H A Lewin
  • M R Teutsch
  • T J Clark
  • L B Schook

Detail Information

Publications7

  1. ncbi Nucleotide sequence of the second exon of a BoLA-DQB gene
    R T Stone
    US Meat Animal Research Center, Clay Center, Nebraska 68933 0166
    Anim Genet 23:273-4. 1992
  2. ncbi Gene duplications and sequence polymorphism of bovine class II DQB genes
    S Sigurdardottir
    Department of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, Uppsala
    Immunogenetics 35:205-13. 1992
    ..Four subtypes of bovine DQB genes were found. DQB1 is the major type and was found in almost all haplotypes...
  3. ncbi Sequencing and genetic analysis of a bovine DQB cDNA clone
    A Xu
    Department of Animal Sciences, University of Illinois, Urbana Champaign
    Anim Genet 22:381-98. 1991
    A BoLA-DQB cDNA clone (BoLA-DQ beta-1) was isolated by screening a bovine lymphoblastoid cDNA library with a HLA-DQB genomic clone. The DNA and predicted protein sequences were compared to class II sequences from cattle and other species...
  4. ncbi The specificity of anti-HLA class II monoclonal antibodies in cattle
    P R Nilsson
    Department of Animal Husbandry, Agricultural University, Wageningen, The Netherlands
    Eur J Immunogenet 24:211-23. 1997
    ..Screening of the available bovine DRB3 and DQB exon 2 sequences revealed that some of the key amino acid (AA) motifs of these epitopes were present in cattle as ..
  5. ncbi Sequence duplication at the 3' end of BoLA-DQB genes suggests multiple allelic lineages
    G C Russell
    Department of Genomics and Bioinformatics, Roslin Institute, Midlothian, UK
    Immunogenetics 52:101-6. 2000
    Full-length cDNAs encoding the DQB genes expressed by three BoLA class II haplotypes (DH8A, DH15B, and DH24A) were amplified by reverse-transcription polymerase chain reaction, cloned, and sequenced...
  6. ncbi Identification of 19 new BoLA-DQB alleles
    K Wang
    Department of Animal Genetics and Breeding, College of Animal Science and Technology, China Agricultural University, Beijing, 100094, China
    Anim Genet 36:166-7. 2005
  7. ncbi Intrahaplotype and interhaplotype pairing of bovine leukocyte antigen DQA and DQB molecules generate functional DQ molecules important for priming CD4(+) T-lymphocyte responses
    Junzo Norimine
    Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164 7040, USA
    Immunogenetics 57:750-62. 2005
    Antigen-specific CD4(+) T-lymphocyte responses are restricted by major histocompatibility complex class II molecules, which influence T-cell priming during infection...