cytochrome c oxidase subunit VIII

Summary

Gene Symbol: cytochrome c oxidase subunit VIII
Description: cytochrome c oxidase subunit 8A
Alias: COX, COX8, COX8-2, COX8L, VIII, VIII-L, cytochrome c oxidase subunit 8A, mitochondrial, cytochrome c oxidase polypeptide VIII-liver/heart, cytochrome c oxidase subunit 8-2, cytochrome c oxidase subunit 8A (ubiquitous), cytochrome c oxidase subunit VIII, cytochrome c oxidase subunit VIIIA (ubiquitous)
Species: human

Top Publications

  1. Xu B, Deng H, Zhang X, Luo J, Zhang G, Zhang Z, et al. A novel Danshensu/tetramethylpyrazine derivative induces vasorelaxation on rat aorta and exerts cardioprotection in dogs. Eur J Pharmacol. 2018;818:158-166 pubmed publisher
    ..In addition, cyclooxygenase (COX), muscarine receptor and β-adrenoceptor were not involved in ADTM-induced vasorelaxation...
  2. Chae H, Song W, Ahn J, Li Q, Lee B, Kweon K, et al. Immunomodulatory effects of soluble factors secreted by feline adipose tissue-derived mesenchymal stem cells. Vet Immunol Immunopathol. 2017;191:22-29 pubmed publisher
    ..The mRNA expression of immunomodulatory factors from fATMSCs, including cyclooxygenase-2 (COX-2), transforming growth factor (TGF)-β, indoleamine-2,3-dioxygenase (IDO) and hepatocyte growth factor, increased ..
  3. Brito B, Mohapatra J, Subramaniam S, Pattnaik B, Rodriguez L, Moore B, et al. Dynamics of widespread foot-and-mouth disease virus serotypes A, O and Asia-1 in southern Asia: A Bayesian phylogenetic perspective. Transbound Emerg Dis. 2017;: pubmed publisher
    ..1990 [1988-1991] for A/G-18 (G-VII); 2003 [2000-2006] for Asia-1 Sindh08 and 2002 [1999-2004] for Asia-1 G-VIII. We estimated the mean of the overall substitution rate of the VP1 coding region (substitution/site/year) for ..
  4. Lildal S, Nørregaard R, Andreassen K, Christiansen F, Jung H, Pedersen M, et al. Ureteral Access Sheath Influence on the Ureteral Wall Evaluated by Cyclooxygenase-2 and Tumor Necrosis Factor-α in a Porcine Model. J Endourol. 2017;31:307-313 pubmed publisher
    To examine the effect of ureteral access sheath (UAS) on the expression of the pro-inflammatory mediators cyclooxygenase-2 (COX-2) and tumor necrosis factor-α (TNF-α) in the ureteral wall.
  5. Liu J, Duan S, Chen P, Cai G, Wang Y, Tang L, et al. Development and validation of a prognostic nomogram for IgA nephropathy. Oncotarget. 2017;8:94371-94381 pubmed publisher
    ..A nomogram was developed using COX regression coefficients to predict decline of estimate Glomerular filtration rate (eGFR) ≥ 50% and end-stage ..
  6. Teeter A, Griffin K, Howard L, Aronson W, Terris M, Kane C, et al. Does Early Prostate Specific Antigen Doubling Time after Radical Prostatectomy, Calculated Prior to PSA Recurrence, Correlate with Prostate Cancer Outcomes? A Report from the SEARCH Database Group. J Urol. 2017;: pubmed publisher
    ..b>Cox models were used to examine the association between early prostate specific antigen doubling time and castration ..
  7. Pippias M, Jager K, Caskey F, Casula A, Erlandsson H, Finne P, et al. Kidney transplant outcomes from older deceased donors: A paired kidney analysis by the ERA-EDTA Registry. Transpl Int. 2017;: pubmed publisher
    ..Paired Cox regression analyses showed a lower risk of graft failure (group 1 younger; adjusted relative risk [RRa]:0...
  8. Slade M, DiPersio J, Westervelt P, Vij R, Schroeder M, Romee R. Haploidentical Hematopoietic Cell Transplant with Post-Transplant Cyclophosphamide and Peripheral Blood Stem Cell Grafts in Older Adults with Acute Myeloid Leukemia or Myelodysplastic Syndrome. Biol Blood Marrow Transplant. 2017;23:1736-1743 pubmed publisher
    ..Overall survival (OS) was analyzed using 3 different Cox proportional hazards models. We identified 112 haplo-HCT patients, 95 with AML and 17 with MDS...
  9. Yousif N, de Oliveira A, Brioschi S, Huell M, Biber K, Fiebich B. Activation of EP2 receptor suppresses poly(I: C) and LPS-mediated inflammation in primary microglia and organotypic hippocampal slice cultures: Contributing role for MAPKs. Glia. 2017;: pubmed publisher
    ..Poly(I:C) induced the production of prostaglandin E2 in OHSCs by increasing cyclooxygenase (COX-2) and microsomal prostaglandin E synthase (mPGES)-1...
  10. Matono T, Nishijima T, Teruya K, Morino E, Takasaki J, Gatanaga H, et al. Substantially Higher and Earlier Occurrence of Anti-Tuberculosis Drug-Related Adverse Reactions in HIV Coinfected Tuberculosis Patients: A Matched-Cohort Study. AIDS Patient Care STDS. 2017;31:455-462 pubmed publisher
    ..HIV infection was an independent risk factor for TB-AEs in the multivariate Cox analysis [adjusted HR (aHR): 6.96; 95% confidence interval: 3.93-12.3]...

Detail Information

Publications62

  1. Xu B, Deng H, Zhang X, Luo J, Zhang G, Zhang Z, et al. A novel Danshensu/tetramethylpyrazine derivative induces vasorelaxation on rat aorta and exerts cardioprotection in dogs. Eur J Pharmacol. 2018;818:158-166 pubmed publisher
    ..In addition, cyclooxygenase (COX), muscarine receptor and β-adrenoceptor were not involved in ADTM-induced vasorelaxation...
  2. Chae H, Song W, Ahn J, Li Q, Lee B, Kweon K, et al. Immunomodulatory effects of soluble factors secreted by feline adipose tissue-derived mesenchymal stem cells. Vet Immunol Immunopathol. 2017;191:22-29 pubmed publisher
    ..The mRNA expression of immunomodulatory factors from fATMSCs, including cyclooxygenase-2 (COX-2), transforming growth factor (TGF)-β, indoleamine-2,3-dioxygenase (IDO) and hepatocyte growth factor, increased ..
  3. Brito B, Mohapatra J, Subramaniam S, Pattnaik B, Rodriguez L, Moore B, et al. Dynamics of widespread foot-and-mouth disease virus serotypes A, O and Asia-1 in southern Asia: A Bayesian phylogenetic perspective. Transbound Emerg Dis. 2017;: pubmed publisher
    ..1990 [1988-1991] for A/G-18 (G-VII); 2003 [2000-2006] for Asia-1 Sindh08 and 2002 [1999-2004] for Asia-1 G-VIII. We estimated the mean of the overall substitution rate of the VP1 coding region (substitution/site/year) for ..
  4. Lildal S, Nørregaard R, Andreassen K, Christiansen F, Jung H, Pedersen M, et al. Ureteral Access Sheath Influence on the Ureteral Wall Evaluated by Cyclooxygenase-2 and Tumor Necrosis Factor-α in a Porcine Model. J Endourol. 2017;31:307-313 pubmed publisher
    To examine the effect of ureteral access sheath (UAS) on the expression of the pro-inflammatory mediators cyclooxygenase-2 (COX-2) and tumor necrosis factor-α (TNF-α) in the ureteral wall.
  5. Liu J, Duan S, Chen P, Cai G, Wang Y, Tang L, et al. Development and validation of a prognostic nomogram for IgA nephropathy. Oncotarget. 2017;8:94371-94381 pubmed publisher
    ..A nomogram was developed using COX regression coefficients to predict decline of estimate Glomerular filtration rate (eGFR) ≥ 50% and end-stage ..
  6. Teeter A, Griffin K, Howard L, Aronson W, Terris M, Kane C, et al. Does Early Prostate Specific Antigen Doubling Time after Radical Prostatectomy, Calculated Prior to PSA Recurrence, Correlate with Prostate Cancer Outcomes? A Report from the SEARCH Database Group. J Urol. 2017;: pubmed publisher
    ..b>Cox models were used to examine the association between early prostate specific antigen doubling time and castration ..
  7. Pippias M, Jager K, Caskey F, Casula A, Erlandsson H, Finne P, et al. Kidney transplant outcomes from older deceased donors: A paired kidney analysis by the ERA-EDTA Registry. Transpl Int. 2017;: pubmed publisher
    ..Paired Cox regression analyses showed a lower risk of graft failure (group 1 younger; adjusted relative risk [RRa]:0...
  8. Slade M, DiPersio J, Westervelt P, Vij R, Schroeder M, Romee R. Haploidentical Hematopoietic Cell Transplant with Post-Transplant Cyclophosphamide and Peripheral Blood Stem Cell Grafts in Older Adults with Acute Myeloid Leukemia or Myelodysplastic Syndrome. Biol Blood Marrow Transplant. 2017;23:1736-1743 pubmed publisher
    ..Overall survival (OS) was analyzed using 3 different Cox proportional hazards models. We identified 112 haplo-HCT patients, 95 with AML and 17 with MDS...
  9. Yousif N, de Oliveira A, Brioschi S, Huell M, Biber K, Fiebich B. Activation of EP2 receptor suppresses poly(I: C) and LPS-mediated inflammation in primary microglia and organotypic hippocampal slice cultures: Contributing role for MAPKs. Glia. 2017;: pubmed publisher
    ..Poly(I:C) induced the production of prostaglandin E2 in OHSCs by increasing cyclooxygenase (COX-2) and microsomal prostaglandin E synthase (mPGES)-1...
  10. Matono T, Nishijima T, Teruya K, Morino E, Takasaki J, Gatanaga H, et al. Substantially Higher and Earlier Occurrence of Anti-Tuberculosis Drug-Related Adverse Reactions in HIV Coinfected Tuberculosis Patients: A Matched-Cohort Study. AIDS Patient Care STDS. 2017;31:455-462 pubmed publisher
    ..HIV infection was an independent risk factor for TB-AEs in the multivariate Cox analysis [adjusted HR (aHR): 6.96; 95% confidence interval: 3.93-12.3]...
  11. Zhang Y, Guo F, Li S, Wang F, Meng Z, Zhao J, et al. Decreased high density lipoprotein cholesterol is an independent predictor for persistent organ failure, pancreatic necrosis and mortality in acute pancreatitis. Sci Rep. 2017;7:8064 pubmed publisher
    ..The association of HDL-C value and other lipids with outcomes was explored with Cox proportional regression models, which were adjusted for confounding factors...
  12. Huang W, Tso T. Etoricoxib improves osteoarthritis pain relief, joint function, and quality of life in the extreme elderly. Bosn J Basic Med Sci. 2017;: pubmed publisher
    Etoricoxib is a selective cyclooxygenase-2 (COX-2) inhibitor, with a lower risk of gastrointestinal toxicity compared to traditional nonsteroidal anti-inflammatory drugs (NSAIDs)...
  13. Bonnesen T, Winther J, Andersen K, Asdahl P, de Fine Licht S, Gudmundsdottir T, et al. Liver diseases in Adult Life after Childhood Cancer in Scandinavia (ALiCCS): A population-based cohort study of 32,839 one-year survivors. Int J Cancer. 2017;: pubmed publisher
    ..We included all 1-year survivors of childhood cancer treated in the five Nordic countries. A Cox proportional hazards model was used to estimate hospitalisation rate (hazard) ratios (HRs) for each liver outcome ..
  14. Zhang X, Ding C, Tian H, Dong X, Meng X, Zhu W, et al. ZNF23 Suppresses Cutaneous Melanoma Cell Malignancy via Mitochondria-Dependent Pathway. Cell Physiol Biochem. 2017;43:147-157 pubmed publisher
    ..By using Cox's regression analysis, ZNF23 expression, tumor thickness and lymph node metastasis were the independent prognostic ..
  15. Yu E, Ruiz Canela M, Guasch Ferré M, Zheng Y, Toledo E, Clish C, et al. Increases in Plasma Tryptophan Are Inversely Associated with Incident Cardiovascular Disease in the Prevención con Dieta Mediterránea (PREDIMED) Study. J Nutr. 2017;147:314-322 pubmed publisher
    ..b>Cox models were used in the primary analysis...
  16. Chen J, Chen W, Chan J, Chen Y, Peng Y, Cheng M, et al. Overexpression of CD164 in oral cavity squamous cell carcinoma predicts a favourable prognosis. Oncol Lett. 2017;14:6103-6108 pubmed publisher
    ..001), buccogingival tumour location (P=0.038) and a CD164 H-score of <120 (P=0.016). Multivariate Cox's regression analyses revealed that poor overall survival rate was associated with advanced-stage disease (P=0...
  17. Szczygieł J, Wieczorek P, Drozd Sokołowska J, Michałek P, Mazurkiewicz Ł, Legatowicz Koprowska M, et al. Impaired right ventricle function as predictor of early mortality in patients with light-chain cardiac amyloidosis assessed in the cardiology department. Pol Arch Intern Med. 2017;: pubmed publisher
    ..They had a higher concentration of troponin T and NT-proBNP and worse left and right ventricle contractility. Cox models containing age, NT-proBNP, right ventricle end-diastolic diameter (RVEDD) and contractility (TAPSE) provide ..
  18. Bruni S, Guglielmi V, Della Foglia E, Castoldi M, Bagnasco Gianni G. A non-destructive spectroscopic study of the decoration of archaeological pottery: from matt-painted bichrome ceramic sherds (southern Italy, VIII-VII B.C.) to an intact Etruscan cinerary urn. Spectrochim Acta A Mol Biomol Spectrosc. 2018;191:88-97 pubmed publisher
    ..reflection Fourier-transform infrared (FTIR) spectroscopy were applied to matt-painted bichrome pottery sherds (VIII-VII century B.C.) from the site of Incoronata near Metaponto in southern Italy...
  19. Wang H, Wang L, Song Y, Wang S, Huang X, Xuan Q, et al. CD44+/CD24- phenotype predicts a poor prognosis in triple-negative breast cancer. Oncol Lett. 2017;14:5890-5898 pubmed publisher
    ..Multivariate Cox regression analyses were performed with regard to the prognostic value of cancer stem cell markers CD44/CD24, ..
  20. Leon Ferre R, Polley M, Liu H, Gilbert J, Cafourek V, Hillman D, et al. Impact of histopathology, tumor-infiltrating lymphocytes, and adjuvant chemotherapy on prognosis of triple-negative breast cancer. Breast Cancer Res Treat. 2017;: pubmed publisher
    ..impact of these parameters on invasive disease-free survival (IDFS) and overall survival (OS) was assessed using Cox proportional hazards models...
  21. Zhang W, Wang X, Wang Y, Zhao X, Duan W, Wang Q, et al. Effective viral suppression is necessary to reduce hepatocellular carcinoma development in cirrhotic patients with chronic hepatitis B: Results of a 10-year follow up. Medicine (Baltimore). 2017;96:e8454 pubmed publisher
    ..The cumulative incidence and risk factors of HCC were evaluated by the Kaplan-Meier method and multivariate Cox proportional hazards models.At baseline, 28 of the 120 patients (23.3%) were cirrhotic...
  22. Nava Catorce M, Acero G, Pedraza Chaverri J, Fragoso G, Govezensky T, Gevorkian G. Alpha-mangostin attenuates brain inflammation induced by peripheral lipopolysaccharide administration in C57BL/6J mice. J Neuroimmunol. 2016;297:20-7 pubmed publisher
    ..from mangosteen pericarp, reduced brain levels of pro-inflammatory cytokine interleukin-6 (IL-6), cyclooxygenase-2 (COX-2) and 18 kDa translocator protein (TSPO) in an animal model of peripheral LPS-induced neuroinflammation...
  23. de Haan J, Haitjema S, den Ruijter H, Pasterkamp G, de Borst G, Teraa M, et al. Growth Differentiation Factor 15 Is Associated With Major Amputation and Mortality in Patients With Peripheral Artery Disease. J Am Heart Assoc. 2017;6: pubmed publisher
    ..64-6.54; P=0.0008]). In the JUVENTAS trial, this was more pronounced in women. Cox proportional multivariable regression models with median follow-up of 3 years, corrected for common confounders, ..
  24. Kim S, Kang T, Kim M, Lee M, Cho S, Paik Y, et al. Initial radiofrequency ablation failure for hepatocellular carcinoma: repeated radiofrequency ablation versus transarterial chemoembolisation. Clin Radiol. 2018;73:216.e1-216.e8 pubmed publisher
    ..Prognostic factors for outcomes were evaluated using the Cox proportional hazards model...
  25. Cho S, Kim D, Won S, Lee J, Park B, Jang E, et al. Impact of anti-rheumatic treatment on cardiovascular risk in Asian patients with rheumatoid arthritis. Semin Arthritis Rheum. 2018;47:501-506 pubmed publisher
    ..85). Corticosteroids (OR = 1.26) and NSAIDs (nonselective NSAIDs: OR = 1.32, Cox-2 inhibitors: OR = 1.31) were risk factors for CVD in RA patients...
  26. Ward M, Riaz N, Caudell J, Dunlap N, Isrow D, Zakem S, et al. Refining Patient Selection for Reirradiation of Head and Neck Squamous Carcinoma in the IMRT Era: A Multi-Institution Cohort Study by the MIRI Collaborative. Int J Radiat Oncol Biol Phys. 2017;: pubmed publisher
    ..Locoregional failure and late toxicity were calculated using the Gray competing risk method. Cox proportional hazards regression was used to identify factors associated with overall survival (OS)...
  27. Kim M, Jung I, Lee J, Na J, Kim W, Kim Y, et al. Pseudane-VII Isolated from Pseudoalteromonas sp. M2 Ameliorates LPS-Induced Inflammatory Response In Vitro and In Vivo. Mar Drugs. 2017;15: pubmed publisher
    ..pseudane-VII treatment dose-dependently reduced mRNA levels of pro-inflammatory cytokines including inos, cox-2, il-1β, tnf-α, and il-6 in LPS-stimulated macrophages...
  28. Silva Santisteban T, Rabajania O, Kalinina I, Robinson S, Meier M. Rapid spheroid clearing on a microfluidic chip. Lab Chip. 2017;18:153-161 pubmed publisher
    ..hydrogel polymerization, lipid extraction, and immuno-fluorescence staining of the mitochondrial protein COX-IV, and metabolic enzyme GAPDH...
  29. Porpiglia F, Fiori C, Bertolo R, Manfredi M, Mele F, Checcucci E, et al. Five-year Outcomes for a Prospective Randomised Controlled Trial Comparing Laparoscopic and Robot-assisted Radical Prostatectomy. Eur Urol Focus. 2016;: pubmed publisher
    ..estimating equations model was used to compare time series data for functional results, and Kaplan-Meier and Cox models were used to analyse oncologic outcomes. The probability of achieving continence (odds ratio [OR] 2...
  30. Wu Z, Zhu S, Hu Y, Gu Y, Wang S, Lin Z, et al. Glibenclamide enhances the effects of delayed hypothermia after experimental stroke in rats. Brain Res. 2016;1643:113-22 pubmed publisher
    ..The combination also improved neurological outcome, ameliorated blood-brain barrier damage and decreased levels of COX-2, TNF-α and IL-1β...
  31. Tsunedomi R, Iizuka N, Yoshimura K, Iida M, Tsutsui M, Hashimoto N, et al. ABCB6 mRNA and DNA methylation levels serve as useful biomarkers for prediction of early intrahepatic recurrence of hepatitis C virus-related hepatocellular carcinoma. Int J Oncol. 2013;42:1551-9 pubmed publisher
    ..Time-to-event analyses for recurrence after surgery were analyzed by Kaplan-Meier analysis and Cox regression analysis with cutoff values obtained from receiver operating characteristic (ROC) analysis...
  32. Hang D, Dong H, Ning T, Dong B, Hou D, Xu W. Prognostic value of the stem cell markers CD133 and ABCG2 expression in esophageal squamous cell carcinoma. Dis Esophagus. 2012;25:638-44 pubmed publisher
    ..Survival analysis was carried out using Kaplan-Meier method and Cox proportional hazards model. CD133 and ABCG2 expression were detected in 27.3% and 15...
  33. Wang Y, Zhang Y, Herman J, Linghu E, Guo M. Epigenetic silencing of TMEM176A promotes esophageal squamous cell cancer development. Oncotarget. 2017;8:70035-70048 pubmed publisher
    ..05). Methylation of TMEM176A was significantly associated with poor 5-year overall survival (p < 0.05). Cox proportional hazards model analysis suggest that TMEM176A methylation is an independent prognostic factor for poor ..
  34. Chow S, Law S, Au S, Mang O, Yau S, Yuen K, et al. Changes in clinical presentation, management and outcome in 1348 patients with differentiated thyroid carcinoma: experience in a single institute in Hong Kong, 1960-2000. Clin Oncol (R Coll Radiol). 2003;15:329-36 pubmed
    ..However, the period of diagnosis was not found to be an important explanatory variable (i.e. P > 0.05) in Cox regression after adjusting for other factors, indicating that the improvement was probably related to the temporal ..
  35. Van den Borre L, Deboosere P. Health risks in the cleaning industry: a Belgian census-linked mortality study (1991-2011). Int Arch Occup Environ Health. 2018;91:13-21 pubmed publisher
    ..Standardized Mortality Ratios were calculated and indirectly adjusted for smoking (SMR). In addition, Cox proportional hazards regression models were used to account for age, educational level, part-time employment and ..
  36. Zhu H, Sun X, Zhang Q, Song P, Hu Q, Zhang X, et al. GLABROUS (CmGL) encodes a HD-ZIP IV transcription factor playing roles in multicellular trichome initiation in melon. Theor Appl Genet. 2017;: pubmed publisher
    ..analysis in a population with 256 F2 plants, which allowed to locate the cmgl locus in melon chromosome VIII. Next-generation sequencing-aided marker discovery and fine mapping in a large population with 1536 F2 ..
  37. Maiwall R, Jamwal K, Bhardwaj A, Bhadoria A, Maras J, Kumar G, et al. SX-Ella Stent Danis Effectively Controls Refractory Variceal Bleed in Patients with Acute-on-Chronic Liver Failure. Dig Dis Sci. 2017;: pubmed publisher
    ..B, n = 53). Matching by propensity risk score (PRS) was done to avoid selection bias. Competing risk Cox regression analysis was done to identify event-specific, i.e., gastrointestinal bleed-related death. Majority (78...
  38. Cakmak S, Hebbern C, Pinault L, Lavigne E, Vanos J, Crouse D, et al. Associations between long-term PM2.5 and ozone exposure and mortality in the Canadian Census Health and Environment Cohort (CANCHEC), by spatial synoptic classification zone. Environ Int. 2017;111:200-211 pubmed publisher
    ..Hazard ratios (HR) for mortality, were related to PM2.5 and ozone using Cox proportional hazards survival models, adjusting for socioeconomic characteristics and individual confounders...
  39. Kuzmiak Glancy S, Covian R, Femnou A, Glancy B, Jaimes R, Wengrowski A, et al. Cardiac performance is limited by oxygen delivery to the mitochondria in the crystalloid-perfused working heart. Am J Physiol Heart Circ Physiol. 2017;:ajpheart.00321.2017 pubmed publisher
    ..OxPhos) is unresolved since myoglobin has a much lower affinity for oxygen than cytochrome c oxidase (COX)...
  40. Traina F, Bordini B, De Fine M, Toni A. Patient weight more than body mass index influences total hip arthroplasty long term survival. Hip Int. 2011;21:694-9 pubmed publisher
    ..Implant survivorship was estimated with use of the Cox proportional hazards model with revision for aseptic loosening as the end point...
  41. Müller C, Perz V, Provasnek C, Quartinello F, Guebitz G, Berg G. Discovery of Polyesterases from Moss-Associated Microorganisms. Appl Environ Microbiol. 2017;83: pubmed publisher
    ..Two promising polyesterase candidates, EstB3 and EstC7, which clustered in family VIII of bacterial lipolytic enzymes, were purified and characterized using the soluble esterase substrate p-nitrophenyl ..
  42. Nissen A, Cook J, Loha E, Lindtjørn B. Proximity to vector breeding site and risk of Plasmodium vivax infection: a prospective cohort study in rural Ethiopia. Malar J. 2017;16:380 pubmed publisher
    ..Data was analysed using Cox regression modelling. Overall the P. vivax infection rate was 12.3/1000 person-years (95% CI 10.5-14.5)...
  43. Wong A, Wilson M, Girnary S, Nojoomi M, Acharya S, Paul S. The optimal orthosis and motion protocol for extensor tendon injury in zones IV-VIII: A systematic review. J Hand Ther. 2017;30:447-456 pubmed publisher
    ..of motion protocol and orthotic treatment for the rehabilitation of proximal extensor tendon injuries (zones IV-VIII)...
  44. Hasegawa W, Yamauchi Y, Yasunaga H, Takeshima H, Sakamoto Y, Jo T, et al. Prognostic nomogram for inpatients with asthma exacerbation. BMC Pulm Med. 2017;17:108 pubmed publisher
    ..We recorded patient characteristics and performed Cox proportional hazards regression analysis to assess the factors associated with all-cause in-hospital mortality...
  45. Choi W, Baek S, Joo E, Yoon S, Kim E, Hong B, et al. Comparison of the effect of spinal anesthesia and general anesthesia on 5-year tumor recurrence rates after transurethral resection of bladder tumors. Oncotarget. 2017;8:87667-87674 pubmed publisher
    ..Tumor recurrence five years after TURB was assessed using multivariate Cox regression model, propensity score analysis (matching and inverse probability of treatment weighting), and Kaplan-..
  46. Chen J, Wang Y, Meng X, Ruan Y, Zou F, Chan H. MRP4 regulates ENaC-dependent CREB/COX-2/PGE2 signaling during embryo implantation. Oncotarget. 2017;8:78520-78529 pubmed publisher
    ..injection of MRP4 inhibitor in mice prior to implantation significantly downregulated implantation markers COX-2, Claudin4 and Lif, and reduced implantation rate...
  47. Farowski F, Bücker V, Vehreschild J, Biehl L, Cruz Aguilar R, Scheid C, et al. Impact of choice, timing, sequence and combination of broad-spectrum antibiotics on the outcome of allogeneic haematopoietic stem cell transplantation. Bone Marrow Transplant. 2017;: pubmed publisher
    ..Patients (CoCoNut) undergoing aSCT from January 2007 to April 2013 were included into a time-dependent multivariate Cox proportional hazards regression model with backward-stepwise selection...
  48. Cetin M, Ozcan Cetin E, Canpolat U, Sasmaz H, Temizhan A, Aydogdu S. Prognostic significance of myocardial energy expenditure and myocardial efficiency in patients with heart failure with reduced ejection fraction. Int J Cardiovasc Imaging. 2017;: pubmed publisher
    ..In Cox regression analysis, per one calorie decrease of MEE was associated 4.3 times increased risk [HR 4.396 (95% CI 1...
  49. Hennequart M, Pilotte L, Cane S, Hoffmann D, Stroobant V, Plaen E, et al. Constitutive IDO1 Expression in Human Tumors Is Driven by Cyclooxygenase-2 and Mediates Intrinsic Immune Resistance. Cancer Immunol Res. 2017;5:695-709 pubmed publisher
    Tumors use various mechanisms to avoid immune destruction. Cyclooxygenase-2 (COX-2) expression may be a driver of immune suppression in melanoma, but the mechanisms involved remain elusive...
  50. Shi H, Li X, Zhu J, Lin C, Zhang Y. [Clinical effect of entecavir versus tenofovir in treatment of HBeAg-positive chronic hepatitis B patients with a high viral load: a comparative analysis]. Zhonghua Gan Zang Bing Za Zhi. 2017;25:721-725 pubmed publisher
    ..The Cox proportional hazards regression model was used to identify the influencing factors for virologic response...
  51. Orr C, Najm A, Biniecka M, McGarry T, Ng C, Young F, et al. Synovial Immunophenotype and Anti-Citrullinated Peptide Antibodies in Rheumatoid Arthritis Patients: Relationship to Treatment Response and Radiologic Prognosis. Arthritis Rheumatol. 2017;69:2114-2123 pubmed publisher
    ..for specific markers of B cells (CD19), T cells (CD3, CD4, and CD8), macrophages (CD68), and blood vessels (factor VIII). Serum CXCL13 levels were quantified by enzyme-linked immunosorbent assay...
  52. Yu J, Dai L, Zhao Q, Liu X, Chen S, Wang A, et al. Association of Cumulative Exposure to Resting Heart Rate with Risk of Stroke in General Population: The Kailuan Cohort Study. J Stroke Cerebrovasc Dis. 2017;26:2501-2509 pubmed publisher
    ..Hazard ratios (HRs) with 95% confidence interval (CI) were calculated using a Cox competing risk model. A total of 46,568 participants were included in the final analysis...
  53. Auerbach B, Littman A, Tinker L, Larson J, Krieger J, Young B, et al. Associations of 100% fruit juice versus whole fruit with hypertension and diabetes risk in postmenopausal women: Results from the Women's Health Initiative. Prev Med. 2017;105:212-218 pubmed publisher
    ..Standardized questionnaires assessed outcomes every 6-12months during a mean 7.8years of follow-up. Cox regression estimated hazard ratios (HR) and 95% confidence intervals (CI) for incident hypertension (n=36,314 ..
  54. Dinesen P, Joensen A, Rix T, Tjønneland A, Schmidt E, Lundbye Christensen S, et al. Effect of Dietary Intake of Saturated Fatty Acids on the Development of Atrial Fibrillation and the Effect of Replacement of Saturated With Monounsaturated and Polyunsaturated Fatty Acids. Am J Cardiol. 2017;120:1129-1132 pubmed publisher
    ..Follow-up was registry-based and data were analyzed using Cox proportional hazards regression...
  55. Kim Y, Yoon D, Park S, Han S, Kim D, Lee K, et al. Dipeptidyl Peptidase-4 Inhibitors and Risk of Heart Failure in Patients With Type 2 Diabetes Mellitus: A Population-Based Cohort Study. Circ Heart Fail. 2017;10: pubmed publisher
    ..The risk of hospitalization for HF was evaluated with a Cox proportional hazards model in 255 691 matched pairs...
  56. Loosen S, Roderburg C, Kauertz K, Koch A, Vucur M, Schneider A, et al. CEA but not CA19-9 is an independent prognostic factor in patients undergoing resection of cholangiocarcinoma. Sci Rep. 2017;7:16975 pubmed publisher
    ..but surprisingly, only CEA but not CA19-9 represented an independent predictor of survival in multivariate Cox-regression analysis...
  57. Geng X, Liu Y, Diersch S, Kotzsch M, Grill S, Weichert W, et al. Clinical relevance of kallikrein-related peptidase 9, 10, 11, and 15 mRNA expression in advanced high-grade serous ovarian cancer. PLoS ONE. 2017;12:e0186847 pubmed publisher
    ..In univariate Cox regression analysis, elevated KLK11 mRNA levels were significantly linked with prolonged overall survival (OS; p = ..
  58. Wu H, Yin Z, Wang L, Li F, Qiu Y. Honokiol improved chondrogenesis and suppressed inflammation in human umbilical cord derived mesenchymal stem cells via blocking nuclear factor-κB pathway. BMC Cell Biol. 2017;18:29 pubmed publisher
    ..IL-1β enhanced cell apoptosis and necrosis and activated the expression of caspase-3, cyclooxygenase-2 (COX-2), interleukin-6 (IL-6) and matrix metalloproteinase (MMP)-1, -9, 13 in hUC-MSCs...
  59. Lenting P, Denis C, Christophe O. Emicizumab, a bispecific antibody recognizing coagulation factors IX and X: how does it actually compare to factor VIII?. Blood. 2017;: pubmed publisher
    ..These approaches include factor VIII (FVIII) with extended half-life (e.g...
  60. Decambron A, Manassero M, Thibaud J, Reyes Gomez E, Viateau V. Bone haemophilic pseudotumour of the ulna: A rare complication of haemophilia in a dog. Vet Comp Orthop Traumatol. 2017;30:371-376 pubmed publisher
    ..Based on prolonged activated partial thromboplastin time (aPTT) and low factor VIII activity, haemophilia A was diagnosed...
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    In adult mammalian testes, spermatids, most notably step 17-19 spermatids in stage IV-VIII tubules, are aligned with their heads pointing toward the basement membrane and their tails toward the tubule lumen...
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    ..Multivariate survival analysis was performed using a Cox regression model...