gnd

Summary

Gene Symbol: gnd
Description: 6-phosphogluconate dehydrogenase
Species: Lactococcus lactis subsp. cremoris MG1363

Top Publications

  1. pmc 6-Phosphogluconate dehydrogenase from Lactococcus lactis: a role for arginine residues in binding substrate and coenzyme
    E Tetaud
    Laboratoire de Biologie Mol├ęculaire et Immunologie de Parasites Protozoaires, UPRESA 5016 CNRS, Universite Bordeaux II, France
    Biochem J 338:55-60. 1999
  2. ncbi Crystal structures of a bacterial 6-phosphogluconate dehydrogenase reveal aspects of specificity, mechanism and mode of inhibition by analogues of high-energy reaction intermediates
    Ramasubramanian Sundaramoorthy
    Division of Biological Chemistry and Molecular Microbiology, College of Life Sciences, University of Dundee, UK
    FEBS J 274:275-86. 2007

Detail Information

Publications2

  1. pmc 6-Phosphogluconate dehydrogenase from Lactococcus lactis: a role for arginine residues in binding substrate and coenzyme
    E Tetaud
    Laboratoire de Biologie Mol├ęculaire et Immunologie de Parasites Protozoaires, UPRESA 5016 CNRS, Universite Bordeaux II, France
    Biochem J 338:55-60. 1999
    ..A second 6-PGDH gene has been identified from the genome of B. subtilis. This second isoform contains an arginine (Arg-34) in this position, suggesting that B. subtilis has two 6-PGDHs with different coenzyme specificities...
  2. ncbi Crystal structures of a bacterial 6-phosphogluconate dehydrogenase reveal aspects of specificity, mechanism and mode of inhibition by analogues of high-energy reaction intermediates
    Ramasubramanian Sundaramoorthy
    Division of Biological Chemistry and Molecular Microbiology, College of Life Sciences, University of Dundee, UK
    FEBS J 274:275-86. 2007
    ..LlPDH can now serve as a model system for structure-based inhibitor design targeting the enzyme from Trypanosoma species...