Car12

Summary

Gene Symbol: Car12
Description: carbonic anhydrase 12
Alias: 2310047E01Rik, AI314958, CA-XII, Ca12, carbonic anhydrase 12, CA XII, carbonate dehydratase XII, carbonic anhydrase XII
Species: mouse

Top Publications

  1. ncbi Localization of carbonic anhydrase XII to the basolateral membrane of H+-secreting cells of mouse and rat kidney
    Matti S Kyllönen
    Departments of Anatomy and Cell Biology, University of Oulu, Oulu, Finland
    J Histochem Cytochem 51:1217-24. 2003
  2. ncbi Transposon vectors for gene-trap insertional mutagenesis in vertebrates
    Karl J Clark
    Department of Genetics, Cell Biology, and Development, Arnold and Mabel Beckman Center for Transposon Research at the University of Minnesota, Minneapolis, Minnesota, USA
    Genesis 39:225-33. 2004
  3. pmc Transmembrane carbonic anhydrase isozymes IX and XII in the female mouse reproductive organs
    Piritta Hynninen
    Department of Gynecology and Obstetrics, University of Tampere and Tampere University Hospital, Tampere, Finland
    Reprod Biol Endocrinol 2:73. 2004
  4. ncbi Expression of hypoxia-inducible, membrane-bound carbonic anhydrase isozyme XII in mouse tissues
    Piia Halmi
    Institute of Medical Technology, University of Tampere and Tampere University Hospital, Tampere, Finland
    Anat Rec A Discov Mol Cell Evol Biol 277:171-7. 2004
  5. ncbi Expression, assay, and structure of the extracellular domain of murine carbonic anhydrase XIV: implications for selective inhibition of membrane-associated isozymes
    Douglas A Whittington
    Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Biol Chem 279:7223-8. 2004
  6. doi Carbonic anhydrase XII in valve interstitial cells promotes the regression of calcific aortic valve stenosis
    Rihab Bouchareb
    Laboratoire d Études Moléculaires des Valvulopathies LEMV, Groupe de Recherche en Valvulopathies GRV, Quebec Heart and Lung Institute Research Center, Department of Surgery, Laval University, Quebec, Canada
    J Mol Cell Cardiol 82:104-15. 2015
  7. doi A systematic survey of carbonic anhydrase mRNA expression during mammalian inner ear development
    Ling Wu
    Department of Anatomy, Yonsei University College of Medicine, Seoul, South Korea
    Dev Dyn 242:269-80. 2013
  8. pmc Expression of carbonic anhydrases IX and XII during mouse embryonic development
    Heini Kallio
    Institute of Medical Technology, University of Tampere and Tampere University Hospital, Biokatu 8, FIN 33520 Tampere, Finland
    BMC Dev Biol 6:22. 2006
  9. pmc Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposon
    Aron M Geurts
    Department of Genetics, Cell Biology, and Development, The Arnold and Mabel Beckman Center for Transposon Research, University of Minnesota, Minneapolis, MN 55455, USA
    BMC Biotechnol 6:30. 2006
  10. pmc A systematic quantification of carbonic anhydrase transcripts in the mouse digestive system
    Pei wen Pan
    Institute of Medical Technology, University of Tampere and Tampere University Hospital, 33520, Tampere, Finland
    BMC Mol Biol 8:22. 2007

Scientific Experts

  • Piritta Hynninen
  • Aron M Geurts
  • Pei wen Pan
  • Heini Kallio
  • Rihab Bouchareb
  • Ling Wu
  • William S Sly
  • Abdul Waheed
  • Douglas A Whittington
  • Karl J Clark
  • Piia Halmi
  • Gul N Shah
  • Seppo Parkkila
  • Jeffrey H Grubb
  • Matti S Kyllönen
  • Ablajan Mahmut
  • Denis Boudreau
  • Younes Messaddeq
  • Fayez Hadji
  • Diala El Husseini
  • Dominic Lachance
  • Jérémie Asselin
  • Yohan Bosse
  • Philippe Pibarot
  • Nancy Côté
  • Patrick Mathieu
  • Khai Le Quang
  • - Marie-Chloé-Boulanger
  • Andre Marette
  • Elnur Elyar Shayhidin
  • Jinwoong Bok
  • Borum Sagong
  • Jae Young Choi
  • Un Kyung Kim
  • Jason B Bell
  • Jonna Lehtonen
  • Perry B Hackett
  • David W Christianson
  • Kari Kaunisto
  • Hannu Rajaniemi

Detail Information

Publications11

  1. ncbi Localization of carbonic anhydrase XII to the basolateral membrane of H+-secreting cells of mouse and rat kidney
    Matti S Kyllönen
    Departments of Anatomy and Cell Biology, University of Oulu, Oulu, Finland
    J Histochem Cytochem 51:1217-24. 2003
    ..CA activity has been localized to both luminal and basolateral membranes of the tubule epithelial cells. CA XII is a transmembrane isoenzyme that has been demonstrated in the basolateral plasma membrane of human renal, ..
  2. ncbi Transposon vectors for gene-trap insertional mutagenesis in vertebrates
    Karl J Clark
    Department of Genetics, Cell Biology, and Development, Arnold and Mabel Beckman Center for Transposon Research at the University of Minnesota, Minneapolis, Minnesota, USA
    Genesis 39:225-33. 2004
    ....
  3. pmc Transmembrane carbonic anhydrase isozymes IX and XII in the female mouse reproductive organs
    Piritta Hynninen
    Department of Gynecology and Obstetrics, University of Tampere and Tampere University Hospital, Tampere, Finland
    Reprod Biol Endocrinol 2:73. 2004
    ..The twelve active CA isozymes are thought to regulate a variety of cellular functions including several processes in the reproductive systems...
  4. ncbi Expression of hypoxia-inducible, membrane-bound carbonic anhydrase isozyme XII in mouse tissues
    Piia Halmi
    Institute of Medical Technology, University of Tampere and Tampere University Hospital, Tampere, Finland
    Anat Rec A Discov Mol Cell Evol Biol 277:171-7. 2004
    ..In mouse, CA XII has been recently localized in the kidney...
  5. ncbi Expression, assay, and structure of the extracellular domain of murine carbonic anhydrase XIV: implications for selective inhibition of membrane-associated isozymes
    Douglas A Whittington
    Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Biol Chem 279:7223-8. 2004
    ..amino acid sequence identity of human CA XIV relative to the other membrane-associated isozymes (CA IV, CA IX, and CA XII) is 34-46%...
  6. doi Carbonic anhydrase XII in valve interstitial cells promotes the regression of calcific aortic valve stenosis
    Rihab Bouchareb
    Laboratoire d Études Moléculaires des Valvulopathies LEMV, Groupe de Recherche en Valvulopathies GRV, Quebec Heart and Lung Institute Research Center, Department of Surgery, Laval University, Quebec, Canada
    J Mol Cell Cardiol 82:104-15. 2015
    ..Calcific aortic valve stenosis (CAVS) is the most common heart valve disease. In the present work we sought to determine the reversibility of mineralization in the aortic valve...
  7. doi A systematic survey of carbonic anhydrase mRNA expression during mammalian inner ear development
    Ling Wu
    Department of Anatomy, Yonsei University College of Medicine, Seoul, South Korea
    Dev Dyn 242:269-80. 2013
    ..To understand the specific roles of CA isozymes in the inner ear, a systematic survey was conducted to reveal temporal and spatial expression patterns of all 16 CA isozymes during inner ear development...
  8. pmc Expression of carbonic anhydrases IX and XII during mouse embryonic development
    Heini Kallio
    Institute of Medical Technology, University of Tampere and Tampere University Hospital, Biokatu 8, FIN 33520 Tampere, Finland
    BMC Dev Biol 6:22. 2006
    ..Since active cell migration is a characteristic feature of embryonic development, we set out to explore whether these isozymes are expressed in mouse embryos of different ages. The studies were focused on organogenesis stage...
  9. pmc Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposon
    Aron M Geurts
    Department of Genetics, Cell Biology, and Development, The Arnold and Mabel Beckman Center for Transposon Research, University of Minnesota, Minneapolis, MN 55455, USA
    BMC Biotechnol 6:30. 2006
    ..We sought to generate a transposon system that would be capable of reporting the expression pattern of a mouse gene while allowing for conditional expression of a gene of interest in a tissue- or temporal-specific pattern...
  10. pmc A systematic quantification of carbonic anhydrase transcripts in the mouse digestive system
    Pei wen Pan
    Institute of Medical Technology, University of Tampere and Tampere University Hospital, 33520, Tampere, Finland
    BMC Mol Biol 8:22. 2007
    ..In the present study, we systematically examined the mRNA expression levels of all known CA isozymes by quantitative real-time PCR in eight tissues of the digestive system of male and female mice...
  11. doi Carbonic anhydrases in the mouse harderian gland
    Pei wen Pan
    Institute of Medical Technology, University of Tampere, Biokatu 6, 33520 Tampere, Finland
    J Mol Histol 41:411-7. 2010
    ..Nine CA mRNAs were detectable in the gland. Car5b and Car13 showed the highest signals. Car4, Car6, and Car12 showed moderate expression levels, whereas Car2, Car3, Car7, and Car15 mRNAs were barely within the detection ..