Gjb4

Summary

Gene Symbol: Gjb4
Description: gap junction protein, beta 4
Alias: Cnx30.3, Cx30.3, Gjb-4, gap junction beta-4 protein, connexin-30.3, gap junction membrane channel protein beta 4
Species: mouse

Top Publications

  1. doi Connexin 30 sets synaptic strength by controlling astroglial synapse invasion
    Ulrike Pannasch
    1 Center for Interdisciplinary Research in Biology, College de France, INSERM U1050, CNRS UMR 7241, Labex Memolife, PSL Research University, Paris, France 2 Doctoral school N 158, Pierre and Marie Curie University, Paris, France 3
    Nat Neurosci 17:549-58. 2014
  2. ncbi Two gap junction genes, connexin 31.1 and 30.3, are closely linked on mouse chromosome 4 and preferentially expressed in skin
    H Hennemann
    Abteilung Molekulargenetik, Universitat Bonn, Germany
    J Biol Chem 267:17225-33. 1992
  3. ncbi The diversity of connexin genes encoding gap junctional proteins
    K Willecke
    Institut für Genetik Abt Molekulargenetik Universität, Bonn Bundersrepublik Deutschland
    Eur J Cell Biol 56:1-7. 1991
  4. ncbi Multiple members of the connexin gene family participate in preimplantation development of the mouse
    T C Davies
    Department of Zoology, University of Western Ontario, London, Canada
    Dev Genet 18:234-43. 1996
  5. ncbi Assignment of connexin 26 (GJB2) and 46 (GJA3) genes to human chromosome 13q11-->q12 and mouse chromosome 14D1-E1 by in situ hybridization
    C Mignon
    INSERM U 406, Faculté de la Timone, Marseille
    Cytogenet Cell Genet 72:185-6. 1996
  6. ncbi Two interactive genes responsible for a new inherited cataract (RCT) in the mouse
    Y Y Maeda
    The Tokyo Metropolitan Institute of Medical Science Rinshoken, Dept of Laboratory Animal Science, Japan
    Mamm Genome 12:278-83. 2001
  7. ncbi An update on connexin genes and their nomenclature in mouse and man
    Goran Sohl
    Institut fur Genetik, Universitat Bonn, Germany
    Cell Commun Adhes 10:173-80. 2003
  8. ncbi An expression atlas of connexin genes in the mouse
    Annalisa Buniello
    Telethon Institute of Genetics and Medicine, Via P Castellino 111, 80131 Naples, Italy
    Genomics 83:812-20. 2004
  9. ncbi mRNA expression pattern of multiple members of connexin gene family in normal and abnormal fetal gonads in mouse
    Subhash C Juneja
    Department of Zoology, The University of Western Ontario, London, Canada
    Indian J Physiol Pharmacol 47:147-56. 2003
  10. ncbi The novel mouse connexin39 gene is expressed in developing striated muscle fibers
    Julia von Maltzahn
    Institut fur Genetik, Abteilung Molekulargenetik, Universitat Bonn, Römerstr 164, 53117 Bonn, Germany
    J Cell Sci 117:5381-92. 2004

Scientific Experts

  • Subhash C Juneja
  • Y Y Maeda
  • Klaus Willecke
  • Qingyi Zheng-Fischhöfer
  • Ulrike Pannasch
  • Goran Sohl
  • Fiona Hanner
  • Marc Schnichels
  • Janos Peti-Peterdi
  • Julia von Maltzahn
  • Annalisa Buniello
  • Nicole Déglon
  • Amandine Dufour
  • Karim Benchenane
  • Gregory Ghezali
  • Martine Cohen-Salmon
  • Carole Escartin
  • David Holcman
  • Glenn Dallérac
  • Dominik Freche
  • Joachim H R Lübke
  • Graham Knott
  • Veronica Abudara
  • Nathalie Rouach
  • Pascal Ezan
  • Li E Yang
  • Alicia A McDonough
  • Ildiko Toma
  • James I Nagy
  • Nadine Loscher
  • Joachim Degen
  • Markus Kretz
  • Harald Reucher
  • Heinz Breer
  • Fiona McCulloch
  • Jörg Strotmann
  • Joseph P Huston
  • Ekrem Dere
  • Carsten Euwens
  • Valeria Marigo
  • Stefano Volinia
  • Donatella Montanaro
  • Paolo Gasparini
  • T C Davies
  • C Mignon
  • M Mesnil
  • D Gros
  • D H Jones
  • K J Barr
  • G M Kidder
  • M G Mattei
  • H Yamasaki
  • D Zhu
  • C Fromaget
  • H Hennemann
  • K Willecke
  • E Dahl
  • B J Nicholson
  • P A Lalley
  • S Chang
  • H J Schwarz
  • J B White
  • S Jungbluth
  • R Heynkes

Detail Information

Publications12

  1. doi Connexin 30 sets synaptic strength by controlling astroglial synapse invasion
    Ulrike Pannasch
    1 Center for Interdisciplinary Research in Biology, College de France, INSERM U1050, CNRS UMR 7241, Labex Memolife, PSL Research University, Paris, France 2 Doctoral school N 158, Pierre and Marie Curie University, Paris, France 3
    Nat Neurosci 17:549-58. 2014
    ..Taken together, these results establish connexin 30 as a critical regulator of synaptic strength by controlling the synaptic location of astroglial processes. ..
  2. ncbi Two gap junction genes, connexin 31.1 and 30.3, are closely linked on mouse chromosome 4 and preferentially expressed in skin
    H Hennemann
    Abteilung Molekulargenetik, Universitat Bonn, Germany
    J Biol Chem 267:17225-33. 1992
    ..Microinjection of Cx30.3, but not Cx31.1 cRNA, into Xenopus oocyte pairs induced formation of functional gap junction channels with unique voltage-gated parameters compared to other connexins expressed similarly...
  3. ncbi The diversity of connexin genes encoding gap junctional proteins
    K Willecke
    Institut für Genetik Abt Molekulargenetik Universität, Bonn Bundersrepublik Deutschland
    Eur J Cell Biol 56:1-7. 1991
    ..The structural diversity of the connexin genes suggests that they fulfill different functions coordinated with, and perhaps required for, different programs of cellular differentiation...
  4. ncbi Multiple members of the connexin gene family participate in preimplantation development of the mouse
    T C Davies
    Department of Zoology, University of Western Ontario, London, Canada
    Dev Genet 18:234-43. 1996
    ..The expression of multiple connexin genes during this early period of embryogenesis (when there are only two distinct cell types) raises questions about the functional significance of connexin diversity in this context...
  5. ncbi Assignment of connexin 26 (GJB2) and 46 (GJA3) genes to human chromosome 13q11-->q12 and mouse chromosome 14D1-E1 by in situ hybridization
    C Mignon
    INSERM U 406, Faculté de la Timone, Marseille
    Cytogenet Cell Genet 72:185-6. 1996
  6. ncbi Two interactive genes responsible for a new inherited cataract (RCT) in the mouse
    Y Y Maeda
    The Tokyo Metropolitan Institute of Medical Science Rinshoken, Dept of Laboratory Animal Science, Japan
    Mamm Genome 12:278-83. 2001
    ..The rct locus essential for the onset of the cataract was tightly linked to D4Mit278 on Chromosome (Chr) 4 with no recombination. The mrct locus was closely linked to D5Mit239 (chi2 = 66.3, P << 0.00001) on Chr 5...
  7. ncbi An update on connexin genes and their nomenclature in mouse and man
    Goran Sohl
    Institut fur Genetik, Universitat Bonn, Germany
    Cell Commun Adhes 10:173-80. 2003
    ..Furthermore, this short review contains an update on phenotypic correlations between connexin deficient mice and patients bearing mutations in their orthologous connexin genes...
  8. ncbi An expression atlas of connexin genes in the mouse
    Annalisa Buniello
    Telethon Institute of Genetics and Medicine, Via P Castellino 111, 80131 Naples, Italy
    Genomics 83:812-20. 2004
    ....
  9. ncbi mRNA expression pattern of multiple members of connexin gene family in normal and abnormal fetal gonads in mouse
    Subhash C Juneja
    Department of Zoology, The University of Western Ontario, London, Canada
    Indian J Physiol Pharmacol 47:147-56. 2003
    ..In developmentally impaired fetal ovary, only Cx43 was not expressed as expected but other three connexins were expresed. The study may be useful in interpreting human testis defects in infertility cases...
  10. ncbi The novel mouse connexin39 gene is expressed in developing striated muscle fibers
    Julia von Maltzahn
    Institut fur Genetik, Abteilung Molekulargenetik, Universitat Bonn, Römerstr 164, 53117 Bonn, Germany
    J Cell Sci 117:5381-92. 2004
    ..As expression of no other known connexin could be verified in these cells, intercellular dye transfer might result from functional expression of Cx39 in developing striated muscle fibers...
  11. ncbi Characterization of connexin30.3-deficient mice suggests a possible role of connexin30.3 in olfaction
    Qingyi Zheng-Fischhöfer
    Institut fur Genetik, Abteilung Molekulargenetik, Römerstrassae 164, D 53117 Bonn, Germany
    Eur J Cell Biol 86:683-700. 2007
    ..Furthermore, they showed normal auditory thresholds as measured by brain stem evoked potentials. These mice did, however, exhibit reduced behavioural responses to a vanilla scent...
  12. doi Connexin 30.3 is expressed in the kidney but not regulated by dietary salt or high blood pressure
    Fiona Hanner
    Department of Physiology and Biophysics, Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, California 90033, USA
    Cell Commun Adhes 15:219-30. 2008
    ..Cx30.3 appears to be constitutively expressed in certain renal tubular segments and cells and its role in overall kidney function remains to be investigated...