Gjc3

Summary

Gene Symbol: Gjc3
Description: gap junction protein, gamma 3
Alias: Cx29, Gje1, connexin 29, connexin-29, gap junction epsilon-1 protein, gap junction gamma-3 protein, gap junction membrane channel protein epsilon 1
Species: mouse

Top Publications

  1. pmc Cx29 and Cx32, two connexins expressed by myelinating glia, do not interact and are functionally distinct
    Meejin Ahn
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6077, USA
    J Neurosci Res 86:992-1006. 2008
  2. ncbi The mouse gap junction gene connexin29 is highly expressed in sciatic nerve and regulated during brain development
    G Sohl
    Institut fur Genetik, Abteilung Molekulargenetik, Universitat Bonn, Germany
    Biol Chem 382:973-8. 2001
  3. doi Dynamic expression of Cx47 in mouse brain development and in the cuprizone model of myelin plasticity
    Rosalba Parenti
    Department of Physiological Science, University of Catania, V le A Doria, 6 95125 Catania, Italy
    Glia 58:1594-609. 2010
  4. pmc Mouse lens connexin23 (Gje1) does not form functional gap junction channels but causes enhanced ATP release from HeLa cells
    Stephan Sonntag
    Institut fur Genetik, Abteilung Molekulargenetik, Universitat Bonn, D 53117 Bonn, Germany
    Eur J Cell Biol 88:65-77. 2009
  5. ncbi Analysis of connexin expression during mouse Schwann cell development identifies connexin29 as a novel marker for the transition of neural crest to precursor cells
    Jing Li
    Department of Neuroanatomy and Molecular Brain Research, Ruhr University Bochum, D 44801 Bochum, Germany
    Glia 55:93-103. 2007
  6. ncbi Connexin29 is highly expressed in cochlear Schwann cells, and it is required for the normal development and function of the auditory nerve of mice
    Wenxue Tang
    Department of Otolaryngology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    J Neurosci 26:1991-9. 2006
  7. ncbi Expression pattern and functional characterization of connexin29 in transgenic mice
    Jürgen Eiberger
    Institut fur Genetik, Universitat Bonn, Bonn, Germany
    Glia 53:601-11. 2006
  8. ncbi Expression patterns of connexin 29 (GJE1) in mouse and rat cochlea
    Jiann jou Yang
    Genetics Laboratory and Department of BioMedical Sciences, Chung Shan Medical University, Taichung, Taiwan, ROC
    Biochem Biophys Res Commun 338:723-8. 2005
  9. ncbi The novel mouse connexin39 gene is expressed in developing striated muscle fibers
    Julia von Maltzahn
    Institut fur Genetik, Abteilung Molekulargenetik, Universitat Bonn, Römerstr 164, 53117 Bonn, Germany
    J Cell Sci 117:5381-92. 2004
  10. ncbi Unique distributions of the gap junction proteins connexin29, connexin32, and connexin47 in oligodendrocytes
    Kleopas A Kleopa
    Department of Neurology, University of Pennsylvania Medical Center, Philadelphia, USA
    Glia 47:346-57. 2004

Scientific Experts

  • J I Nagy
  • Kleopas A Kleopa
  • Rosalba Parenti
  • Klaus Willecke
  • David L Paul
  • Goran Sohl
  • Bruce M Altevogt
  • Jürgen Eiberger
  • Younghye Moon
  • Stephan Sonntag
  • Meejin Ahn
  • Elke Winterhager
  • Jing Li
  • Wenxue Tang
  • Steven S Scherer
  • Jiann jou Yang
  • Julia von Maltzahn
  • Annalisa Buniello
  • Xinbo Li
  • G Sohl
  • So Yoen Choi
  • Woong Sun
  • Kyungjin Kim
  • Hyun Kim
  • Radoslaw Dobrowolski
  • Feliksas F Bukauskas
  • Martin Theis
  • Jiong Zhang
  • Jai Yoon Sul
  • Yan Huang
  • Jonathan Lee
  • Alan Enriquez
  • Charles K Abrams
  • Andreas Gustafsson
  • Philip G Haydon
  • Eric Lancaster
  • Carola Meier
  • Hans Werner Habbes
  • Rolf Dermietzel
  • Qing Chang
  • Harald Reucher
  • Ian Dahlke
  • Yanping Zhang
  • Hong Yi
  • Xi Lin
  • Nicola Strenzke
  • Carsten Wessig
  • Shoab Ahmad
  • Heinrich Bussow
  • Dirk Alex Koch
  • Sina Djahed
  • Andreas Schober
  • Ping Chen
  • Mark Kibschull
  • Tobias Moser
  • Jürgen Lautermann
  • Shuan Yow Li
  • Ching Chyuan Su
  • Pei Ju Liao
  • Stefano Volinia
  • Valeria Marigo
  • Donatella Montanaro
  • Carsten Euwens
  • Paolo Gasparini
  • T Yasumura
  • B D Lynn
  • Friso R Postma
  • C Olson
  • J E Rash
  • K G V Davidson
  • C Meier
  • J Eiberger
  • C A Kozak
  • Y T Jung
  • K Willecke

Detail Information

Publications17

  1. pmc Cx29 and Cx32, two connexins expressed by myelinating glia, do not interact and are functionally distinct
    Meejin Ahn
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104 6077, USA
    J Neurosci Res 86:992-1006. 2008
    In rodents, oligodendrocytes and myelinating Schwann cells express connexin32 (Cx32) and Cx29, which have different localizations in the two cell types...
  2. ncbi The mouse gap junction gene connexin29 is highly expressed in sciatic nerve and regulated during brain development
    G Sohl
    Institut fur Genetik, Abteilung Molekulargenetik, Universitat Bonn, Germany
    Biol Chem 382:973-8. 2001
    ..Our expression data suggest that the new connexin gene is active in myelin-forming glial cells...
  3. doi Dynamic expression of Cx47 in mouse brain development and in the cuprizone model of myelin plasticity
    Rosalba Parenti
    Department of Physiological Science, University of Catania, V le A Doria, 6 95125 Catania, Italy
    Glia 58:1594-609. 2010
    ..Since the expression of Cx47 in developing oligodendrocytes preceded those of Cx32 and Cx29, a role of Cx47 in myelinogenesis was postulated...
  4. pmc Mouse lens connexin23 (Gje1) does not form functional gap junction channels but causes enhanced ATP release from HeLa cells
    Stephan Sonntag
    Institut fur Genetik, Abteilung Molekulargenetik, Universitat Bonn, D 53117 Bonn, Germany
    Eur J Cell Biol 88:65-77. 2009
    ..The mouse connexin23 (Cx23) gene (Gje1) differs from all other connexin genes in vertebrates, since it codes for a protein that contains only 4 instead of ..
  5. ncbi Analysis of connexin expression during mouse Schwann cell development identifies connexin29 as a novel marker for the transition of neural crest to precursor cells
    Jing Li
    Department of Neuroanatomy and Molecular Brain Research, Ruhr University Bochum, D 44801 Bochum, Germany
    Glia 55:93-103. 2007
    ..In mature myelin-forming Schwann cells, expression of multiple connexins, i.e. connexin (Cx) 43, Cx29, Cx32, and Cx46 (after nerve injury) has been detected...
  6. ncbi Connexin29 is highly expressed in cochlear Schwann cells, and it is required for the normal development and function of the auditory nerve of mice
    Wenxue Tang
    Department of Otolaryngology, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    J Neurosci 26:1991-9. 2006
    ..Here, we show that Cx29 was highly expressed in the cochlea...
  7. ncbi Expression pattern and functional characterization of connexin29 in transgenic mice
    Jürgen Eiberger
    Institut fur Genetik, Universitat Bonn, Bonn, Germany
    Glia 53:601-11. 2006
    Using newly generated transgenic mice in which the coding region of the connexin29 (Cx29) gene was replaced by the lacZ reporter gene, we confirmed previous immunochemical results that Cx29 is expressed in Schwann cells, oligodendrocytes ..
  8. ncbi Expression patterns of connexin 29 (GJE1) in mouse and rat cochlea
    Jiann jou Yang
    Genetics Laboratory and Department of BioMedical Sciences, Chung Shan Medical University, Taichung, Taiwan, ROC
    Biochem Biophys Res Commun 338:723-8. 2005
    ..To elucidate whether the Cx29 gap junction protein epsilon 1, GJE1, is localized in the adult mouse and rat cochlea, we performed an immunohistochemistry (IHC) and reverse ..
  9. ncbi The novel mouse connexin39 gene is expressed in developing striated muscle fibers
    Julia von Maltzahn
    Institut fur Genetik, Abteilung Molekulargenetik, Universitat Bonn, Römerstr 164, 53117 Bonn, Germany
    J Cell Sci 117:5381-92. 2004
    ..As expression of no other known connexin could be verified in these cells, intercellular dye transfer might result from functional expression of Cx39 in developing striated muscle fibers...
  10. ncbi Unique distributions of the gap junction proteins connexin29, connexin32, and connexin47 in oligodendrocytes
    Kleopas A Kleopa
    Department of Neurology, University of Pennsylvania Medical Center, Philadelphia, USA
    Glia 47:346-57. 2004
    Oligodendrocytes of adult rodents express three different connexins: connexin29 (Cx29), Cx32, and Cx47...
  11. ncbi Four classes of intercellular channels between glial cells in the CNS
    Bruce M Altevogt
    Program in Neuroscience and Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Neurosci 24:4313-23. 2004
    ..We produced a Cx29 reporter mouse in which the connexin coding sequence was replaced with a histological marker, which was used to ..
  12. ncbi An expression atlas of connexin genes in the mouse
    Annalisa Buniello
    Telethon Institute of Genetics and Medicine, Via P Castellino 111, 80131 Naples, Italy
    Genomics 83:812-20. 2004
    ....
  13. ncbi An update on connexin genes and their nomenclature in mouse and man
    Goran Sohl
    Institut fur Genetik, Universitat Bonn, Germany
    Cell Commun Adhes 10:173-80. 2003
    ..Furthermore, this short review contains an update on phenotypic correlations between connexin deficient mice and patients bearing mutations in their orthologous connexin genes...
  14. pmc Connexin29 and connexin32 at oligodendrocyte and astrocyte gap junctions and in myelin of the mouse central nervous system
    James I Nagy
    Department of Physiology, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba R3E 3J7, Canada
    J Comp Neurol 464:356-70. 2003
    The cellular localization, relation to other glial connexins (Cx30, Cx32, and Cx43), and developmental expression of Cx29 were investigated in the mouse central nervous system (CNS) with an anti-Cx29 antibody...
  15. pmc Connexin29 expression, immunocytochemistry and freeze-fracture replica immunogold labelling (FRIL) in sciatic nerve
    Xinbo Li
    Department of Physiology, Faculty of Medicine, University of Manitoba, 730 William Avenue, Winnipeg, Manitoba, R3E 3J7 Canada
    Eur J Neurosci 16:795-806. 2002
    The recently discovered connexin29 (Cx29) was reported to be present in the central and peripheral nervous systems (CNS and PNS), and its mRNA was found in particular abundance in peripheral nerve...
  16. ncbi Connexin29 is uniquely distributed within myelinating glial cells of the central and peripheral nervous systems
    Bruce M Altevogt
    Department of Neurobiology, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Neurosci 22:6458-70. 2002
    ..We identified Cx29, whose transcript was restricted to brain, spinal cord, and sciatic nerve...
  17. doi Expression of connexin29 and 32 in the penumbra region after traumatic brain injury of mice
    Younghye Moon
    Department of Anatomy, Korea University College of Medicine, Seoul, Korea
    Neuroreport 21:1135-9. 2010
    ..We found that the expressions of two Cx family members, Cx29 and Cx32, were progressively increased in the sharp border of injury penumbra regions after cryotraumatic brain ..