FABP4

Summary

Gene Symbol: FABP4
Description: fatty acid binding protein 4, adipocyte
Alias: A-FABP, AFABP, ALBP, AP2, FABP3, adipocyte lipid-binding protein, adipocyte-type fatty acid-binding protein, fatty acid-binding protein 4, fatty acid-binding protein, adipocyte
Species: pig

Top Publications

  1. doi Developmental changes and effect on intramuscular fat content of H-FABP and A-FABP mRNA expression in pigs
    Qi Mei Chen
    College of Animal Science and Technology, Shandong Agricultural University, 61 Daizong Street, Tai an, 271018, People s Republic of China
    J Appl Genet 54:119-23. 2013
  2. doi Two-dimensional fluorescence in-gel electrophoresis of coronary restenosis tissues in minipigs: increased adipocyte fatty acid binding protein induces reactive oxygen species-mediated growth and migration in smooth muscle cells
    Lin Lu
    Institute of Cardiovascular Diseases, Rui Jin Hospital, Medical School of Jiaotong University, Shanghai, PR China
    Arterioscler Thromb Vasc Biol 33:572-80. 2013
  3. doi Association of A-FABP gene polymorphism in intron 1 with meat quality traits in Junmu No. 1 white swine
    Yan Gao
    Laboratory Animal Center, Jilin University, China
    Gene 487:170-3. 2011
  4. ncbi Genomic changes in regenerated porcine coronary arterial endothelial cells
    Mary Y K Lee
    Department of Pharmacology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 2F Laboratory Block, 21 Sassoon Road, Pokfulam, Hong Kong
    Arterioscler Thromb Vasc Biol 27:2443-9. 2007
  5. pmc Unexpected high polymorphism at the FABP4 gene unveils a complex history for pig populations
    Ana Ojeda
    Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, Bellaterra, Spain
    Genetics 174:2119-27. 2006
  6. pmc The purification and characterization of a fatty acid binding protein specific to pig (Sus domesticus) adipose tissue
    M K Armstrong
    Reproduction and Growth Physiology Research, Unit 7921, Upjohn Company, Kalamazoo, MI 49001
    Biochem J 267:373-8. 1990
  7. ncbi Number of intramuscular adipocytes and fatty acid binding protein-4 content are significant indicators of intramuscular fat level in crossbred Large White x Duroc pigs
    M Damon
    Unité Mixte de Recherches Systèmes d Elevage Nutrition Animale et Humaine, Institut National de la Recherche Agronomique, 35590 Saint Gilles, France
    J Anim Sci 84:1083-92. 2006
  8. ncbi Liver fatty acid-binding protein: an early and sensitive plasma marker of hepatocellular damage and a reliable predictor of graft viability after liver transplantation from non-heart-beating donors
    D Monbaliu
    University Hospitals Leuven Leuven, Belgium
    Transplant Proc 37:413-6. 2005
  9. ncbi Expression of porcine adipocyte transcripts: tissue distribution and differentiation in vitro and in vivo
    S T Ding
    Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030 2600, USA
    Comp Biochem Physiol B Biochem Mol Biol 123:307-18. 1999
  10. ncbi The adipocyte fatty acid-binding protein locus: characterization and association with intramuscular fat content in pigs
    F Gerbens
    DLO Institute for Animal Science and Health ID DLO, P O Box 65, 8200 AB Lelystad, The Netherlands
    Mamm Genome 9:1022-6. 1998

Scientific Experts

  • D Monbaliu
  • M Damon
  • Anna Mercadé
  • Lin Lu
  • Qi Mei Chen
  • Yan Gao
  • Mary Y K Lee
  • Ana Ojeda
  • Li Jin Pu
  • Wei Chen
  • Ling Jie Wang
  • Ya nan Wang
  • Ping Yang
  • Yong Qing Zeng
  • Zhu Hui Liu
  • Ke Yang
  • Zhen Bin Zhu
  • Qi Zhang
  • Hui Wang
  • Hua Meng
  • Hong Yu
  • Qiu Jing Chen
  • Wei Feng Shen
  • Wei hua Sun
  • Li Shun Wang
  • Run Du
  • Shuqi Xiao
  • Shumin Zhang
  • Hao Jiang
  • Zhihui Zhao
  • Dianfeng Liu
  • Jiabao Bao Zhang
  • Yonghong Hong Zhang
  • Fujuan Li
  • Boxing Sun
  • Lisheng Dai
  • Shuai Wang
  • S T Ding
  • Shu Guang Zhu
  • Hung Fat Tse
  • Ricky Y K Man
  • Chung Wah Siu
  • Paul M Vanhoutte
  • F Gerbens
  • Josep M Folch
  • Miguel Perez-Enciso
  • Julio Rozas
  • R L McNeel
  • H J Mersmann
  • M F te Pas
  • A Jansen
  • A J van Erp
  • J H Veerkamp
  • T H Meuwissen
  • G Rettenberger
  • F Harders
  • M K Armstrong
  • J Storch
  • S D Clarke
  • D A Bernlohr

Detail Information

Publications11

  1. doi Developmental changes and effect on intramuscular fat content of H-FABP and A-FABP mRNA expression in pigs
    Qi Mei Chen
    College of Animal Science and Technology, Shandong Agricultural University, 61 Daizong Street, Tai an, 271018, People s Republic of China
    J Appl Genet 54:119-23. 2013
    ..05). In conclusion, the A-FABP gene is strongly related to the development and function of IMF accretion in pigs...
  2. doi Two-dimensional fluorescence in-gel electrophoresis of coronary restenosis tissues in minipigs: increased adipocyte fatty acid binding protein induces reactive oxygen species-mediated growth and migration in smooth muscle cells
    Lin Lu
    Institute of Cardiovascular Diseases, Rui Jin Hospital, Medical School of Jiaotong University, Shanghai, PR China
    Arterioscler Thromb Vasc Biol 33:572-80. 2013
    ..quantitative 2-dimensional fluorescence in-gel electrophoresis (2D-DIGE), and to investigate the influences of crucial proteins identified, particularly adipocyte fatty acid binding protein (AFABP), in human arterial smooth muscle cells.
  3. doi Association of A-FABP gene polymorphism in intron 1 with meat quality traits in Junmu No. 1 white swine
    Yan Gao
    Laboratory Animal Center, Jilin University, China
    Gene 487:170-3. 2011
    ..Expression was markedly reduced in DD compared with genotype CC. Thus A-FABP may be a candidate gene or a quantitative trait locus-linked gene associated with meat quality traits...
  4. ncbi Genomic changes in regenerated porcine coronary arterial endothelial cells
    Mary Y K Lee
    Department of Pharmacology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 2F Laboratory Block, 21 Sassoon Road, Pokfulam, Hong Kong
    Arterioscler Thromb Vasc Biol 27:2443-9. 2007
    ..Genomic changes were defined in cultures of regenerated porcine coronary endothelial cells to explain the alterations that underlie their dysfunction...
  5. pmc Unexpected high polymorphism at the FABP4 gene unveils a complex history for pig populations
    Ana Ojeda
    Departament de Ciencia Animal i dels Aliments, Universitat Autonoma de Barcelona, Bellaterra, Spain
    Genetics 174:2119-27. 2006
    Fatty acid bing protein 4 (FABP4) plays a key role in fat regulation in mammals and is a strong positional candidate gene for the FAT1 quantitative trait locus located on porcine chromosome 4...
  6. pmc The purification and characterization of a fatty acid binding protein specific to pig (Sus domesticus) adipose tissue
    M K Armstrong
    Reproduction and Growth Physiology Research, Unit 7921, Upjohn Company, Kalamazoo, MI 49001
    Biochem J 267:373-8. 1990
    ..0 microM. Northern-blot analysis using the cDNA for the murine 3T3-L1 FABP revealed that the pig a-FABP was expressed exclusively in adipose tissue...
  7. ncbi Number of intramuscular adipocytes and fatty acid binding protein-4 content are significant indicators of intramuscular fat level in crossbred Large White x Duroc pigs
    M Damon
    Unité Mixte de Recherches Systèmes d Elevage Nutrition Animale et Humaine, Institut National de la Recherche Agronomique, 35590 Saint Gilles, France
    J Anim Sci 84:1083-92. 2006
    ..49). The current study suggests that FABP-4 protein content may be a valuable marker of lipid accretion in LM and that i.m. fat content and myofiber type composition can be manipulated independently...
  8. ncbi Liver fatty acid-binding protein: an early and sensitive plasma marker of hepatocellular damage and a reliable predictor of graft viability after liver transplantation from non-heart-beating donors
    D Monbaliu
    University Hospitals Leuven Leuven, Belgium
    Transplant Proc 37:413-6. 2005
    ..In a pig model for liver transplantation (LTx) from non-heart-beating donors (NHBD), we evaluated plasma changes of L-FABP early after reperfusion of grafts exposed to increasing periods of warm ischemia (WI)...
  9. ncbi Expression of porcine adipocyte transcripts: tissue distribution and differentiation in vitro and in vivo
    S T Ding
    Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030 2600, USA
    Comp Biochem Physiol B Biochem Mol Biol 123:307-18. 1999
    ..adipocyte-characteristic protein transcripts (lipoprotein lipase (LPL) and adipocyte fatty acid binding protein (aP2)) were measured in pig tissues...
  10. ncbi The adipocyte fatty acid-binding protein locus: characterization and association with intramuscular fat content in pigs
    F Gerbens
    DLO Institute for Animal Science and Health ID DLO, P O Box 65, 8200 AB Lelystad, The Netherlands
    Mamm Genome 9:1022-6. 1998
    The porcine A-FABP gene (FABP4) was isolated and sequenced to study the role of A-FABP in the differentiation of intramuscular fat (IMF) accretion in pigs...
  11. ncbi Adipocyte fatty-acid binding protein is closely associated to the porcine FAT1 locus on chromosome 4
    A Mercade
    Departament de Ciencia Animal i dels Aliments, Facultat de Veterinaria, Universitat Autonoma de Barcelona, 08193, Bellaterra, Spain
    J Anim Sci 84:2907-13. 2006
    We identified 22 polymorphisms in the adipocyte fatty-acid binding protein (FABP4) gene, a strong positional candidate gene for the FAT1 locus in porcine chromosome 4...