GNAS

Summary

Gene Symbol: GNAS
Description: GNAS complex locus
Alias: NESP55, PORGSA1, SCG6, guanine nucleotide-binding protein G(s) subunit alpha, SCG6 (secretogranin VI), adenylate cyclase-stimulating G alpha protein, alpha-stimulatory subunit of GTP-binding protein, guanine nucleotide-binding protein G(s), alpha subunit, guanine nucleotide-binding protein, alpha-stimulating activity polypeptide 1, secretogranin VI
Species: pig

Top Publications

  1. doi Lack of the associations of the polymorphisms in IGF2, MC4R and GNAS genes with reproduction traits in pigs and imprinting analysis of IGF2 gene in ovary and cornus uteri
    M Oczkowicz
    Laboratory of Genomics, National Research Institute of Animal Production, Cracow, Poland
    Reprod Domest Anim 48:562-8. 2013
  2. doi Molecular cloning and expression analysis of the GNAS gene in pig and porcine fibroblast cells
    J Peng
    College of Animal Sciences, Zhejiang University, Hangzhou, China
    Genet Mol Res 13:5463-73. 2014
  3. doi Expression and imprinting analysis of the NESP55 gene in pigs
    Maria Oczkowicz
    Laboratory of Genomics, National Research Institute of Animal Production, Krakowska 1, 32 083 Balice, Poland
    Gene Expr Patterns 12:18-23. 2012
  4. doi Genetic suppression of Gαs protein provides rate control in atrial fibrillation
    Patrick Lugenbiel
    Department of Cardiology, University of Heidelberg, Medical University Hospital, Germany
    Basic Res Cardiol 107:265. 2012
  5. ncbi Comparative porcine gene mapping relative to human chromosomes 9, 10, 20 and 22
    J H Lee
    Centre for Advanced Technologies in Animal Genetics and Reproduction, Faculty of Veterinary Science, University of Sydney, NSW 2006, Australia
    Anim Genet 32:313-5. 2001
  6. ncbi Meiotic resumption of porcine immature oocytes is prevented by ooplasmic Gsalpha functions
    Marie Morikawa
    Laboratory of Applied Genetics, Graduate School of Agriculture and Life Science, University of Tokyo, Tokyo, Japan
    J Reprod Dev 53:1151-7. 2007
  7. ncbi Mapping of the porcine FBN2, YWHAQ, CNN3, DCN, POSTN, SPARC, RBM39 and GNAS genes, expressed in foetal skeletal muscles
    A Stratil
    Institute of Animal Physiology and Genetics, Academy of Sciences of the Czech Republic, 277 21 Libechov, Czech Republic
    Anim Genet 39:204-5. 2008
  8. pmc The GNAS Locus: Quintessential Complex Gene Encoding Gsalpha, XLalphas, and other Imprinted Transcripts
    Murat Bastepe
    Endocrine Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Curr Genomics 8:398-414. 2007

Scientific Experts

  • Antonin Stratil
  • J Peng
  • M Oczkowicz
  • Patrick Lugenbiel
  • Maria Oczkowicz
  • Murat Bastepe
  • Marie Morikawa
  • N Y Xu
  • Y F Shen
  • Y L Li
  • Y Wang
  • K Piórkowska
  • M Tyra
  • A Mucha
  • K Ropka-Molik
  • Olympia Bikou
  • Rüdiger Becker
  • Frederik Voss
  • Agata Piestrzyńska-Kajtoch
  • Alexander Bauer
  • Kerstin Trappe
  • Barbara Rejduch
  • Dierk Thomas
  • Katarzyna Ropka-Molik
  • Kamilla Kelemen
  • J H Lee
  • Patrick A Schweizer
  • Hugo A Katus
  • Robert Eckert
  • Kunihiko Naito
  • Sachi Kume
  • Yukio Nishimura
  • Tsutomu Endo
  • Mami Seki
  • Kiyoshi Kano
  • C Moran
  • W Zhang

Detail Information

Publications8

  1. doi Lack of the associations of the polymorphisms in IGF2, MC4R and GNAS genes with reproduction traits in pigs and imprinting analysis of IGF2 gene in ovary and cornus uteri
    M Oczkowicz
    Laboratory of Genomics, National Research Institute of Animal Production, Cracow, Poland
    Reprod Domest Anim 48:562-8. 2013
    ..In our study, we investigated associations between polymorphisms in IGF2, GNAS and MC4R genes with reproductive traits of Polish Landrace and Large White pigs...
  2. doi Molecular cloning and expression analysis of the GNAS gene in pig and porcine fibroblast cells
    J Peng
    College of Animal Sciences, Zhejiang University, Hangzhou, China
    Genet Mol Res 13:5463-73. 2014
    The Alpha subunit of the stimulatory guanine nucleotide-binding protein (GNAS) is a complex imprinted gene...
  3. doi Expression and imprinting analysis of the NESP55 gene in pigs
    Maria Oczkowicz
    Laboratory of Genomics, National Research Institute of Animal Production, Krakowska 1, 32 083 Balice, Poland
    Gene Expr Patterns 12:18-23. 2012
    ..The function of NESP55 (Neuroendocrine secretory protein 55) remains elusive, although there are suggestions about its role in brain ..
  4. doi Genetic suppression of Gαs protein provides rate control in atrial fibrillation
    Patrick Lugenbiel
    Department of Cardiology, University of Heidelberg, Medical University Hospital, Germany
    Basic Res Cardiol 107:265. 2012
    ..Rate control by gene therapy may provide an alternative to current pharmacological treatment of AF...
  5. ncbi Comparative porcine gene mapping relative to human chromosomes 9, 10, 20 and 22
    J H Lee
    Centre for Advanced Technologies in Animal Genetics and Reproduction, Faculty of Veterinary Science, University of Sydney, NSW 2006, Australia
    Anim Genet 32:313-5. 2001
    ....
  6. ncbi Meiotic resumption of porcine immature oocytes is prevented by ooplasmic Gsalpha functions
    Marie Morikawa
    Laboratory of Applied Genetics, Graduate School of Agriculture and Life Science, University of Tokyo, Tokyo, Japan
    J Reprod Dev 53:1151-7. 2007
    ....
  7. ncbi Mapping of the porcine FBN2, YWHAQ, CNN3, DCN, POSTN, SPARC, RBM39 and GNAS genes, expressed in foetal skeletal muscles
    A Stratil
    Institute of Animal Physiology and Genetics, Academy of Sciences of the Czech Republic, 277 21 Libechov, Czech Republic
    Anim Genet 39:204-5. 2008
  8. pmc The GNAS Locus: Quintessential Complex Gene Encoding Gsalpha, XLalphas, and other Imprinted Transcripts
    Murat Bastepe
    Endocrine Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
    Curr Genomics 8:398-414. 2007
    ..The maternal GNAS allele leads to NESP55, a chromogranin-like neuroendocrine secretory protein...