FMO1

Summary

Gene Symbol: FMO1
Description: Fmo1p
Species: Saccharomyces cerevisiae S288c

Top Publications

  1. pmc Yeast flavin-containing monooxygenase generates oxidizing equivalents that control protein folding in the endoplasmic reticulum
    J K Suh
    Institute of Cellular and Molecular Biology, Department of Chemistry and Biochemistry, University of Texas, Austin, TX 78712, USA
    Proc Natl Acad Sci U S A 96:2687-91. 1999
  2. ncbi Lysine 219 participates in NADPH specificity in a flavin-containing monooxygenase from Saccharomyces cerevisiae
    J K Suh
    Department of Chemistry, University of Texas, Austin, Texas, 78712, USA
    Arch Biochem Biophys 372:360-6. 1999
  3. pmc Salicylic acid-independent ENHANCED DISEASE SUSCEPTIBILITY1 signaling in Arabidopsis immunity and cell death is regulated by the monooxygenase FMO1 and the Nudix hydrolase NUDT7
    Michael Bartsch
    Department of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, D 50829 Cologne, Germany
    Plant Cell 18:1038-51. 2006

Detail Information

Publications3

  1. pmc Yeast flavin-containing monooxygenase generates oxidizing equivalents that control protein folding in the endoplasmic reticulum
    J K Suh
    Institute of Cellular and Molecular Biology, Department of Chemistry and Biochemistry, University of Texas, Austin, TX 78712, USA
    Proc Natl Acad Sci U S A 96:2687-91. 1999
    ..The enzyme is required for the proper folding, in the ER, of test proteins with disulfide bonds, whereas those without disulfide bonds are properly folded independently of yFMO in the ER or in the cytoplasm...
  2. ncbi Lysine 219 participates in NADPH specificity in a flavin-containing monooxygenase from Saccharomyces cerevisiae
    J K Suh
    Department of Chemistry, University of Texas, Austin, Texas, 78712, USA
    Arch Biochem Biophys 372:360-6. 1999
    ..Dissociation constants for NADP(+) to oxidized yFMO were measured spectroscopically. K(d) is 12 microM for the wild-type enzyme and 243 microM for the K219A mutant, consistent with the role of Lys 219 in pyridine nucleotide binding...
  3. pmc Salicylic acid-independent ENHANCED DISEASE SUSCEPTIBILITY1 signaling in Arabidopsis immunity and cell death is regulated by the monooxygenase FMO1 and the Nudix hydrolase NUDT7
    Michael Bartsch
    Department of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, D 50829 Cologne, Germany
    Plant Cell 18:1038-51. 2006
    ..FLAVIN-DEPENDENT MONOOXYGENASE1 (FMO1) positively regulates the EDS1 pathway, and one member (NUDT7) of a family of cytosolic Nudix hydrolases exerts ..