Genomes and Genes
Gene Symbol: FMO1
Species: Saccharomyces cerevisiae S288c
- Yeast flavin-containing monooxygenase generates oxidizing equivalents that control protein folding in the endoplasmic reticulumJ K Suh
Institute of Cellular and Molecular Biology, Department of Chemistry and Biochemistry, University of Texas, Austin, TX 78712, USA
Proc Natl Acad Sci U S A 96:2687-91. 1999..The enzyme is required for the proper folding, in the ER, of test proteins with disulfide bonds, whereas those without disulfide bonds are properly folded independently of yFMO in the ER or in the cytoplasm...
- Lysine 219 participates in NADPH specificity in a flavin-containing monooxygenase from Saccharomyces cerevisiaeJ K Suh
Department of Chemistry, University of Texas, Austin, Texas, 78712, USA
Arch Biochem Biophys 372:360-6. 1999..Dissociation constants for NADP(+) to oxidized yFMO were measured spectroscopically. K(d) is 12 microM for the wild-type enzyme and 243 microM for the K219A mutant, consistent with the role of Lys 219 in pyridine nucleotide binding...
- Salicylic acid-independent ENHANCED DISEASE SUSCEPTIBILITY1 signaling in Arabidopsis immunity and cell death is regulated by the monooxygenase FMO1 and the Nudix hydrolase NUDT7Michael Bartsch
Department of Plant Microbe Interactions, Max Planck Institute for Plant Breeding Research, D 50829 Cologne, Germany
Plant Cell 18:1038-51. 2006..FLAVIN-DEPENDENT MONOOXYGENASE1 (FMO1) positively regulates the EDS1 pathway, and one member (NUDT7) of a family of cytosolic Nudix hydrolases exerts ..