AHBP-1B

Summary

Gene Symbol: AHBP-1B
Description: bZIP transcription factor family protein
Alias: AtTGA2, MOJ9.12, MOJ9_12, TGA2, TGACG sequence-specific binding protein 2
Species: thale cress

Top Publications

  1. pmc Interaction of NPR1 with basic leucine zipper protein transcription factors that bind sequences required for salicylic acid induction of the PR-1 gene
    Y Zhang
    Developmental, Cell, and Molecular Biology Group, Department of Botany, Box 91000, Duke University, Durham, NC 27708 1000, USA
    Proc Natl Acad Sci U S A 96:6523-8. 1999
  2. pmc The BTB/POZ domain of the Arabidopsis disease resistance protein NPR1 interacts with the repression domain of TGA2 to negate its function
    Patrick Boyle
    Department of Biological Sciences, Brock University, St Catharines, Ontario, Canada
    Plant Cell 21:3700-13. 2009
  3. doi Arabidopsis thaliana class-II TGA transcription factors are essential activators of jasmonic acid/ethylene-induced defense responses
    Mark Zander
    Albrecht von Haller Institut fuer Pflanzenwissenschaften, Georg August Universitaet Goettingen, Untere Karspuele 2, D 37073 Goettingen, Germany
    Plant J 61:200-10. 2010
  4. pmc Proteasome-mediated turnover of the transcription coactivator NPR1 plays dual roles in regulating plant immunity
    Steven H Spoel
    Department of Biology, Duke University, Durham, NC 27708, USA
    Cell 137:860-72. 2009
  5. pmc Nuclear activity of ROXY1, a glutaredoxin interacting with TGA factors, is required for petal development in Arabidopsis thaliana
    Shutian Li
    Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany
    Plant Cell 21:429-41. 2009
  6. pmc The Arabidopsis GRAS protein SCL14 interacts with class II TGA transcription factors and is essential for the activation of stress-inducible promoters
    Benjamin Fode
    Albrecht von Haller Institut fur Pflanzenwissenschaften, Georg August Universitat Gottingen, D 37073 Gottingen, Germany
    Plant Cell 20:3122-35. 2008
  7. ncbi SA-inducible Arabidopsis glutaredoxin interacts with TGA factors and suppresses JA-responsive PDF1.2 transcription
    Ivan Ndamukong
    Albrecht von Haller Institut fur Pflanzenwissenschaften, Georg August Universitat Gottingen, Untere Karspüle 2, D 37073 Gottingen, Germany
    Plant J 50:128-39. 2007
  8. pmc Genetic interactions of TGA transcription factors in the regulation of pathogenesis-related genes and disease resistance in Arabidopsis
    Meenu Kesarwani
    Department of Biology, Duke University, Durham, NC 27708, USA
    Plant Physiol 144:336-46. 2007
  9. pmc The coactivator function of Arabidopsis NPR1 requires the core of its BTB/POZ domain and the oxidation of C-terminal cysteines
    Amanda Rochon
    Department of Biological Sciences, Brock University, St Catharines, Ontario, Canada L2S 3A1
    Plant Cell 18:3670-85. 2006
  10. pmc BLADE-ON-PETIOLE-dependent signaling controls leaf and floral patterning in Arabidopsis
    Shelley R Hepworth
    Department of Botany, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z4
    Plant Cell 17:1434-48. 2005

Scientific Experts

  • Meenu Kesarwani
  • Ralf R Weigel
  • Christopher D Deppmann
  • Benjamin F Matthews
  • Henrik U Stotz
  • Mark Zander
  • Pierre R Fobert
  • Christiane Gatz
  • Amanda Rochon
  • Charles Despres
  • Jhadeswar Murmu
  • Shutian Li
  • Corinna Thurow
  • Patrick Boyle
  • Benjamin Fode
  • Shelley R Hepworth
  • Yuelin Zhang
  • Zi Shi
  • Juan Vicente Canet
  • J P Fonseca
  • Sabine Zachgo
  • Steven H Spoel
  • Christopher Johnson
  • Ivan Ndamukong
  • Xinnian Dong
  • Xin Li
  • Hong Gu Kang
  • Guosheng Liu
  • Han Suk Kim
  • Weihua Fan
  • Yi Liu
  • Joseph Verica
  • Siela Maximova
  • Mark J Guiltinan
  • Pablo Tornero
  • Albor Dobon
  • R Subramaniam
  • Shuxia Chen
  • Jana Fajmonová
  • Julia Imkampe
  • Catherine DeLong
  • M Menossi
  • Caroline Malcolmson
  • Mingli Xu
  • Sylvain La Camera
  • C D Town
  • C Despres
  • Michael J Bush
  • J M Zhou
  • Jean Pierre Metraux
  • F Thibaud-Nissen
  • Madiha Khan
  • Olivier Lamotte
  • Natalie W Spivey
  • Yasuomi Tada
  • Jee Yan Chu
  • Andrea Busch
  • Andrea Lauri
  • Mrinal Bhave
  • Zhonglin Mou
  • Heather L Shearer
  • Pascal Genschik
  • Errol Le Su
  • Mark Ziemann
  • Y Zhang
  • Jonathan Arias
  • Tanja Siemsen
  • Amy Mhatre
  • Ayed Al Abdallat
  • Donglin Bi
  • Qingguo Zhao
  • Na Qu
  • Tracy Wignes
  • Yu Ti Cheng
  • George W Haughn
  • Daniel F Klessig
  • Jose M Alonso
  • Sarah McKim
  • Eric B Holub
  • Joseph R Ecker
  • Rena Clark
  • Darrell Desveaux
  • Terry Bethune
  • Catherine Chubak
  • S de Pater
  • Terrence P Delaney
  • S W Michnick
  • N Brisson
  • D Desveaux
  • C Spickler

Detail Information

Publications32

  1. pmc Interaction of NPR1 with basic leucine zipper protein transcription factors that bind sequences required for salicylic acid induction of the PR-1 gene
    Y Zhang
    Developmental, Cell, and Molecular Biology Group, Department of Botany, Box 91000, Duke University, Durham, NC 27708 1000, USA
    Proc Natl Acad Sci U S A 96:6523-8. 1999
    ..thaliana PR-1 gene. These data suggest that NPR1 may regulate PR-1 gene expression by interacting with a subclass of basic leucine zipper protein transcription factors...
  2. pmc The BTB/POZ domain of the Arabidopsis disease resistance protein NPR1 interacts with the repression domain of TGA2 to negate its function
    Patrick Boyle
    Department of Biological Sciences, Brock University, St Catharines, Ontario, Canada
    Plant Cell 21:3700-13. 2009
    b>TGA2 and NONEXPRESSER OF PR GENES1 (NPR1) are activators of systemic acquired resistance (SAR) and of the SAR marker gene pathogenesis-related-1 (PR-1) in Arabidopsis thaliana...
  3. doi Arabidopsis thaliana class-II TGA transcription factors are essential activators of jasmonic acid/ethylene-induced defense responses
    Mark Zander
    Albrecht von Haller Institut fuer Pflanzenwissenschaften, Georg August Universitaet Goettingen, Untere Karspuele 2, D 37073 Goettingen, Germany
    Plant J 61:200-10. 2010
    The three closely related Arabidopsis basic leucine zipper (bZIP) transcription factors TGA2, TGA5 and TGA6 are required for the establishment of the salicylic acid (SA)-dependent plant defense response systemic acquired resistance, which ..
  4. pmc Proteasome-mediated turnover of the transcription coactivator NPR1 plays dual roles in regulating plant immunity
    Steven H Spoel
    Department of Biology, Duke University, Durham, NC 27708, USA
    Cell 137:860-72. 2009
    ..These in vivo data demonstrate dual roles for coactivator turnover in both preventing and stimulating gene transcription to regulate plant immunity...
  5. pmc Nuclear activity of ROXY1, a glutaredoxin interacting with TGA factors, is required for petal development in Arabidopsis thaliana
    Shutian Li
    Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany
    Plant Cell 21:429-41. 2009
    ..Additionally, ROXY1 affects later petal morphogenesis, probably by modulating other TGA factors that might act redundantly during differentiation of second whorl organs...
  6. pmc The Arabidopsis GRAS protein SCL14 interacts with class II TGA transcription factors and is essential for the activation of stress-inducible promoters
    Benjamin Fode
    Albrecht von Haller Institut fur Pflanzenwissenschaften, Georg August Universitat Gottingen, D 37073 Gottingen, Germany
    Plant Cell 20:3122-35. 2008
    ..Chromatin immunoprecipitation experiments revealed that class II TGA factors TGA2, TGA5, and/or TGA6 are needed to recruit SCL14 to promoters of selected SCL14 target genes identified by whole-..
  7. ncbi SA-inducible Arabidopsis glutaredoxin interacts with TGA factors and suppresses JA-responsive PDF1.2 transcription
    Ivan Ndamukong
    Albrecht von Haller Institut fur Pflanzenwissenschaften, Georg August Universitat Gottingen, Untere Karspüle 2, D 37073 Gottingen, Germany
    Plant J 50:128-39. 2007
    ..further regulatory proteins of SA-dependent signaling pathways, a yeast protein interaction screen with tobacco TGA2.2 as bait and an Arabidopsis thaliana cDNA prey library was performed and led to the identification of a member of ..
  8. pmc Genetic interactions of TGA transcription factors in the regulation of pathogenesis-related genes and disease resistance in Arabidopsis
    Meenu Kesarwani
    Department of Biology, Duke University, Durham, NC 27708, USA
    Plant Physiol 144:336-46. 2007
    ..A triple-knockout mutant tga2-1 tga5-1 tga6-1 was shown previously to be defective in the induction of PR genes and systemic acquired resistance, ..
  9. pmc The coactivator function of Arabidopsis NPR1 requires the core of its BTB/POZ domain and the oxidation of C-terminal cysteines
    Amanda Rochon
    Department of Biological Sciences, Brock University, St Catharines, Ontario, Canada L2S 3A1
    Plant Cell 18:3670-85. 2006
    ..We show that TGA2 and NPR1 are recruited to PR-1 independently of each other and of SA treatment...
  10. pmc BLADE-ON-PETIOLE-dependent signaling controls leaf and floral patterning in Arabidopsis
    Shelley R Hepworth
    Department of Botany, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z4
    Plant Cell 17:1434-48. 2005
    ....
  11. ncbi An Arabidopsis NPR1-like gene, NPR4, is required for disease resistance
    Guosheng Liu
    National Research Council, Plant Biotechnology Institute, 110 Gymnasium Place, Saskatoon, SK S7N 0W9, Canada
    Plant J 41:304-18. 2005
    ..These results indicate that NPR4 is required for basal defense against pathogens, and that it may be implicated in the cross-talk between the SA- and JA-dependent signaling pathways...
  12. pmc The Arabidopsis NPR1 disease resistance protein is a novel cofactor that confers redox regulation of DNA binding activity to the basic domain/leucine zipper transcription factor TGA1
    Charles Despres
    Department of Biological Sciences, Brock University, St Catharines, Ontario, Canada L2S 3A1
    Plant Cell 15:2181-91. 2003
    ..Unlike its animal and yeast counterparts, the DNA binding activity of TGA1 is not redox regulated; however, this property is conferred by interaction with the NPR1 cofactor...
  13. pmc The Arabidopsis NPR1/NIM1 protein enhances the DNA binding activity of a subgroup of the TGA family of bZIP transcription factors
    C Despres
    National Research Council Canada, Plant Biotechnology Institute, 110 Gymnasium Place, Saskatoon, Saskatchewan, Canada S7N 0W9
    Plant Cell 12:279-90. 2000
    ..In the electrophoretic mobility shift assay, NPR1 substantially increased the binding of TGA2 to its cognate promoter element (as-1) as well as to a positive salicylic acid-inducible element (LS7) and a ..
  14. ncbi Negative regulation of defense responses in Arabidopsis by two NPR1 paralogs
    Yuelin Zhang
    National Institute of Biological Sciences, 7 Science Park Road, Zhongguancun Life Science Park, Beijing, People s Republic of China 102206
    Plant J 48:647-56. 2006
    ..NPR3 and NPR4 interact with TGA2, TGA3, TGA5 and TGA6 in yeast two-hybrid assays...
  15. pmc A tandem affinity purification tag of TGA2 for isolation of interacting proteins in Arabidopsis thaliana
    Henrik U Stotz
    a Julius von Sachs Institute für Biowissenschaften Pharmazeutische Biologie Universität Würzburg Würzburg, Germany
    Plant Signal Behav 9:e972794. 2014
    ..Type II bZIP transcription factors (TGA2, TGA5 and TGA6) play key roles in pathways that control salicylic acid, ethylene, xenobiotic and reactive oxylipin ..
  16. pmc Arabidopsis genes, AtNPR1, AtTGA2 and AtPR-5, confer partial resistance to soybean cyst nematode (Heterodera glycines) when overexpressed in transgenic soybean roots
    Benjamin F Matthews
    United States Department of Agriculture, Agricultural Research Service, Soybean Genomics and Improvement Laboratory, Beltsville, MD 20705, USA
    BMC Plant Biol 14:96. 2014
    ..Several reports demonstrate that SA limits nematode reproduction...
  17. ncbi NIMIN-1, NIMIN-2 and NIMIN-3, members of a novel family of proteins from Arabidopsis that interact with NPR1/NIM1, a key regulator of systemic acquired resistance in plants
    R R Weigel
    Universitat Hohenheim, Institut fur Genetik, FG Allgemeine Virologie, Stuttgart, Germany
    Plant Mol Biol 46:143-60. 2001
    ..Taken together, these data indicate that the NIMIN proteins, via physical interaction with NPR1/NIM1, are part of the signal transduction pathway leading to SAR gene expression in Arabidopsis...
  18. pmc Interaction of NIMIN1 with NPR1 modulates PR gene expression in Arabidopsis
    Ralf R Weigel
    Albrecht von Haller Institut fuer Pflanzenwissenschaften, Allgemeine und Entwicklungsphysiologie, Georg August Universitaet Goettingen, 37073 Goettingen, Germany
    Plant Cell 17:1279-91. 2005
    ..Our results strongly suggest that NIMIN1 negatively regulates distinct functions of NPR1, providing a mechanism to modulate specific features of SAR...
  19. ncbi Cross-species annotation of basic leucine zipper factor interactions: Insight into the evolution of closed interaction networks
    Christopher D Deppmann
    Department of Biological Sciences, Purdue University, USA
    Mol Biol Evol 23:1480-92. 2006
    ..Finally, we discuss the fundamental similarities and differences between dimerization networks within the context of bZIP factor evolution...
  20. pmc TGA transcription factors and jasmonate-independent COI1 signalling regulate specific plant responses to reactive oxylipins
    Henrik U Stotz
    Julius von Sachs Institute für Biowissenschaften, Pharmazeutische Biologie, Universitat Wurzburg, Wurzburg, Germany
    J Exp Bot 64:963-75. 2013
    ..Whereas JA-isoleucine signals through binding to COI1, the bZIP transcription factors TGA2, TGA5, and TGA6 are involved in regulation of gene expression in response to phytoprostanes...
  21. pmc The BLADE-ON-PETIOLE genes of Arabidopsis are essential for resistance induced by methyl jasmonate
    Juan Vicente Canet
    Instituto de Biología Molecular y Celular de Plantas IBMCP, Universidad Politécnica de Valencia UPV Consejo Superior de Investigaciones Científicas CSIC, Ciudad Politécnica de la Innovación CPI, Valencia, Spain
    BMC Plant Biol 12:199. 2012
    ..Since an allelic series of npr1 was recently described, the behavior of these alleles was tested in response to methyl jasmonate...
  22. doi The salicylic acid receptor NPR3 is a negative regulator of the transcriptional defense response during early flower development in Arabidopsis
    Zi Shi
    The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802, USA
    Mol Plant 6:802-16. 2013
    ..The physical interaction between NPR3 and NPR1/TGA2 was explored using bimolecular fluorescence complementation analysis in onion epidermal cells...
  23. ncbi NPR1 differentially interacts with members of the TGA/OBF family of transcription factors that bind an element of the PR-1 gene required for induction by salicylic acid
    J M Zhou
    Waksman Institute and Department of Molecular Biology and Biochemistry, Rutgers, The State University of New Jersey, Piscataway 08854 8020, USA
    Mol Plant Microbe Interact 13:191-202. 2000
    ..Six TGA family members were tested and shown to differentially interact with NPR1: TGA2 and TGA3 showed strong affinity for NPR1; TGA5 and TGA6 exhibited weaker affinity; and TGA1 and TGA4 displayed ..
  24. doi Repression of the Arabidopsis thaliana jasmonic acid/ethylene-induced defense pathway by TGA-interacting glutaredoxins depends on their C-terminal ALWL motif
    Mark Zander
    Albrecht von Haller Institute for Plant Sciences, Georg August University Gottingen, Gottingen, Germany
    Mol Plant 5:831-40. 2012
    ..JA)/ethylene (ET)-induced defense genes through an unknown mechanism that requires clade II transcription factors TGA2, TGA5, and/or TGA6...
  25. ncbi Binding specificity and tissue-specific expression pattern of the Arabidopsis bZIP transcription factor TGA2
    S de Pater
    Center for Phytotechnology, Leiden University, The Netherlands
    Mol Gen Genet 250:237-9. 1996
    The binding specificity and tissue-specific expression pattern of TGA2 (AHBP-1b), an Arabidopsis bZIP transcription factor have been determined...
  26. pmc Arabidopsis basic leucine-zipper transcription factors TGA9 and TGA10 interact with floral glutaredoxins ROXY1 and ROXY2 and are redundantly required for anther development
    Jhadeswar Murmu
    Department of Biology, Carleton University, Ottawa, Ontario, Canada
    Plant Physiol 154:1492-504. 2010
    ....
  27. doi Functional analysis of a TGA factor-binding site located in the promoter region controlling salicylic acid-induced NIMIN-1 expression in Arabidopsis
    J P Fonseca
    Departamento de Genetica, Evolução e Bioagentes, Universidade Estadual de Campinas, Campinas, SP, Brasil
    Genet Mol Res 9:167-75. 2010
    ..We investigated whether the TGA2-binding motif TGACG located upstream of the NIMIN-1 gene is necessary for SA induction of NIMIN-1 expression...
  28. ncbi Direct visualization of protein interactions in plant cells
    R Subramaniam
    Department of Biochemistry, Universite de Montreal, Montreal, Canada H3C 3J7
    Nat Biotechnol 19:769-72. 2001
    ..We demonstrate that the interaction between Arabidopsis NPR1/NIM1 and the bZIP factor TGA2 is induced by the regulators of SAR, salicylic acid (SA), and its analog 2,6-dichloroisonicotinic acid (INA) with ..
  29. doi NPR1 preferentially binds to the DNA-inactive form of Arabidopsis TGA2
    Christopher Johnson
    University of Maryland Baltimore County, MD, USA
    Biochim Biophys Acta 1779:583-9. 2008
    ..case of PR-1, transcriptional activation involves promoter-specific recruitment of transcription factors such as TGA2 through a mechanism that may involve transient physical interaction with the NPR1 protein...
  30. pmc In vivo interaction between NPR1 and transcription factor TGA2 leads to salicylic acid-mediated gene activation in Arabidopsis
    Weihua Fan
    Developmental, Cell, and Molecular Biology Group, Department of Biology, Duke University, Durham, NC 27708 1000, USA
    Plant Cell 14:1377-89. 2002
    ..analysis, NPR1 has been suggested to interact with members of the TGA family of transcription factors, including TGA2 (AHBP-1b)...
  31. ncbi Over-expression of TGA5, which encodes a bZIP transcription factor that interacts with NIM1/NPR1, confers SAR-independent resistance in Arabidopsis thaliana to Peronospora parasitica
    Han Suk Kim
    Cornell University, Department of Plant Pathology, 360 Plant Science Bldg, Ithaca, NY 14853, USA
    Plant J 32:151-63. 2002
    ..We identified, in a yeast two-hybrid screen, two NIM1/NPR1 interacting proteins, TGA2 and TGA5, which belong to the basic region, leucine zipper (bZIP) family of transcription factors...
  32. ncbi Salicylic acid-inducible Arabidopsis CK2-like activity phosphorylates TGA2
    Hong Gu Kang
    Boyce Thompson Institute for Plant Research, Tower Road, Ithaca, NY 14853, USA
    Plant Mol Biol 57:541-57. 2005
    We demonstrate that TGA2, TGA5 and TGA6, and TGA3 to a lesser extent, are phosphorylated by an activity in rabbit reticulocytes...