CRY2

Summary

Gene Symbol: CRY2
Description: cryptochrome 2
Alias: AT-PHH1, ATCRY2, CRYPTOCHROME 2 APOPROTEIN, F19P19.14, F19P19_14, FHA, PHH1, cryptochrome 2
Species: thale cress

Top Publications

  1. ncbi Nuclear localization of the Arabidopsis blue light receptor cryptochrome 2
    O Kleiner
    FB Biologie Botanik, Philipps Universitat, Marburg, Germany
    Plant J 19:289-96. 1999
  2. pmc Formation of Arabidopsis Cryptochrome 2 photobodies in mammalian nuclei: application as an optogenetic DNA damage checkpoint switch
    Irem Ozkan-Dagliyan
    Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
    J Biol Chem 288:23244-51. 2013
  3. pmc Arabidopsis cryptochrome 2 (CRY2) functions by the photoactivation mechanism distinct from the tryptophan (trp) triad-dependent photoreduction
    Xu Li
    Bioenergy and Biomaterial Research Center, Hunan University, Changsha 410082, China
    Proc Natl Acad Sci U S A 108:20844-9. 2011
  4. pmc Blue light-dependent interaction of CRY2 with SPA1 regulates COP1 activity and floral initiation in Arabidopsis
    Zecheng Zuo
    College of Life Sciences, Hunan University, Changsha 410082, China
    Curr Biol 21:841-7. 2011
  5. pmc Rapid blue-light-mediated induction of protein interactions in living cells
    Matthew J Kennedy
    Department of Neurobiology, Duke University Medical Center, Durham North Carolina, USA
    Nat Methods 7:973-5. 2010
  6. doi Differential petiole growth in Arabidopsis thaliana: photocontrol and hormonal regulation
    Frank F Millenaar
    Plant Ecophysiology, Institute of Environmental Biology, Utrecht University, 3584 CA, Utrecht, The Netherlands
    New Phytol 184:141-52. 2009
  7. pmc Formation of nuclear bodies of Arabidopsis CRY2 in response to blue light is associated with its blue light-dependent degradation
    Xuhong Yu
    Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, California 90095, USA
    Plant Cell 21:118-30. 2009
  8. doi Photoexcited CRY2 interacts with CIB1 to regulate transcription and floral initiation in Arabidopsis
    Hongtao Liu
    Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, CA 90095, USA
    Science 322:1535-9. 2008
  9. pmc Arabidopsis cryptochrome 2 completes its posttranslational life cycle in the nucleus
    Xuhong Yu
    Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, California 90095, USA
    Plant Cell 19:3146-56. 2007
  10. ncbi Light-regulated large-scale reorganization of chromatin during the floral transition in Arabidopsis
    Federico Tessadori
    Nuclear Organization Group, Swammerdam Institute for Life Sciences, BioCentrum Amsterdam, University of Amsterdam, Kruislaan 318, 1098 SM, Amsterdam, The Netherlands
    Plant J 50:848-57. 2007

Scientific Experts

  • Hernan E Boccalandro
  • M Ahmad
  • Enrique Lopez-Juez
  • Chentao Lin
  • Xuhong Yu
  • Hongtao Liu
  • Qin Wang
  • John Klejnot
  • Xuanming Liu
  • Bin Liu
  • Xu Li
  • Xiaoying Zhao
  • Hong Quan Yang
  • Hongyun Yang
  • Alfred Batschauer
  • Kun Peng Jia
  • Yawen Liu
  • Chandra L Tucker
  • Matthew J Kennedy
  • Robert M Hughes
  • Ze Cheng Zuo
  • Martijn van Zanten
  • Frank F Millenaar
  • Federico Tessadori
  • Maskit Maymon
  • Qing Liu
  • Ullas V Pedmale
  • Yan Chun Zhang
  • Mingdi Bian
  • Min Young Kang
  • Nathalie Jourdan
  • Mayu Nakagawa
  • Amir Taslimi
  • Yin Liu
  • Yi Cui
  • Christopher Engelhard
  • Robert Bittl
  • Vera Herbel
  • Peter D Gould
  • Shu Tang Tan
  • Yihai Wang
  • Irem Ozkan-Dagliyan
  • Yi Sang
  • Christian Orth
  • Sheng Bo He
  • Jian Mao
  • Guido Weidler
  • Hong Li Lian
  • Zecheng Zuo
  • Rim Nefissi
  • Kunwu Li
  • Xu Hong Yu
  • Chen Tao Lin
  • Rae Dong Jeong
  • Laurentius A C J Voesenek
  • Anton J M Peeters
  • Aziz Sancar
  • Roel van Driel
  • Paul Fransz
  • Yue Jun Yang
  • Janet Lee
  • Xiaojun Kang
  • Xiaodong Xu
  • Javier Lopez
  • Dror Shalitin
  • Motomu Endo
  • Sezgin Ozgur
  • Roberto C Canamero
  • Qing Hua Li
  • Priya Sridevi
  • Craig W Whippo
  • Karin Ljung
  • Joseph R Nery
  • Mark Zander
  • Wei Wang
  • Pedro A B Reis
  • Shao Shan Carol Huang
  • Kazumasa Nito
  • Zhenming Yang
  • Xinglin Du
  • Jonathan Hetzel
  • Xu Wang
  • Joon Park
  • Joseph R Ecker
  • Benjamin J Cole
  • Joanne Chory
  • Hye Young Kwon
  • James A Wohlschlegel
  • Carlos F Martino
  • Jung Nam Cho

Detail Information

Publications51

  1. ncbi Nuclear localization of the Arabidopsis blue light receptor cryptochrome 2
    O Kleiner
    FB Biologie Botanik, Philipps Universitat, Marburg, Germany
    Plant J 19:289-96. 1999
    The cryptochrome blue light photoreceptor family of Arabidopsis thaliana consists of two members, CRY1 and CRY2 (PHH1). CRY2 contains a putative nuclear localization signal (NLS) within its C-terminal region...
  2. pmc Formation of Arabidopsis Cryptochrome 2 photobodies in mammalian nuclei: application as an optogenetic DNA damage checkpoint switch
    Irem Ozkan-Dagliyan
    Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
    J Biol Chem 288:23244-51. 2013
    ..Here, we have expressed Arabidopsis CRY2 (AtCRY2) in mammalian cells and analyzed its fate after blue light exposure to understand the requirements for PB ..
  3. pmc Arabidopsis cryptochrome 2 (CRY2) functions by the photoactivation mechanism distinct from the tryptophan (trp) triad-dependent photoreduction
    Xu Li
    Bioenergy and Biomaterial Research Center, Hunan University, Changsha 410082, China
    Proc Natl Acad Sci U S A 108:20844-9. 2011
    ..We investigated this hypothesis by analyzing the photochemical and physiological activities of Arabidopsis cryptochrome 2 (CRY2) mutations altered in each of the three trp-triad residues...
  4. pmc Blue light-dependent interaction of CRY2 with SPA1 regulates COP1 activity and floral initiation in Arabidopsis
    Zecheng Zuo
    College of Life Sciences, Hunan University, Changsha 410082, China
    Curr Biol 21:841-7. 2011
    ..We report here that Arabidopsis CRY2 (cryptochrome 2) undergoes blue light-dependent interaction with the COP1-interacting protein SUPPRESSOR OF PHYTOCHROME A 1 (..
  5. pmc Rapid blue-light-mediated induction of protein interactions in living cells
    Matthew J Kennedy
    Department of Neurobiology, Duke University Medical Center, Durham North Carolina, USA
    Nat Methods 7:973-5. 2010
    ..Here we describe genetically encoded light-inducible protein-interaction modules based on Arabidopsis thaliana cryptochrome 2 and CIB1 that require no exogenous ligands and dimerize on blue-light exposure with subsecond time resolution ..
  6. doi Differential petiole growth in Arabidopsis thaliana: photocontrol and hormonal regulation
    Frank F Millenaar
    Plant Ecophysiology, Institute of Environmental Biology, Utrecht University, 3584 CA, Utrecht, The Netherlands
    New Phytol 184:141-52. 2009
    ....
  7. pmc Formation of nuclear bodies of Arabidopsis CRY2 in response to blue light is associated with its blue light-dependent degradation
    Xuhong Yu
    Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, California 90095, USA
    Plant Cell 21:118-30. 2009
    Arabidopsis thaliana cryptochrome 2 (CRY2) mediates photoperiodic promotion of floral initiation and blue light inhibition of hypocotyl elongation...
  8. doi Photoexcited CRY2 interacts with CIB1 to regulate transcription and floral initiation in Arabidopsis
    Hongtao Liu
    Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, CA 90095, USA
    Science 322:1535-9. 2008
    ..CIB1 interacts with CRY2 (cryptochrome 2) in a blue light-specific manner in yeast and Arabidopsis cells, and it acts together with additional CIB1-..
  9. pmc Arabidopsis cryptochrome 2 completes its posttranslational life cycle in the nucleus
    Xuhong Yu
    Department of Molecular, Cell, and Developmental Biology, University of California, Los Angeles, California 90095, USA
    Plant Cell 19:3146-56. 2007
    b>CRY2 is a blue light receptor regulating light inhibition of hypocotyl elongation and photoperiodic flowering in Arabidopsis thaliana...
  10. ncbi Light-regulated large-scale reorganization of chromatin during the floral transition in Arabidopsis
    Federico Tessadori
    Nuclear Organization Group, Swammerdam Institute for Life Sciences, BioCentrum Amsterdam, University of Amsterdam, Kruislaan 318, 1098 SM, Amsterdam, The Netherlands
    Plant J 50:848-57. 2007
    ..A mutant analysis indicated that the blue-light photoreceptor CRYPTOCHROME 2 is involved in triggering chromatin decondensation, suggesting a light-signaling pathway towards large-scale ..
  11. pmc Derepression of the NC80 motif is critical for the photoactivation of Arabidopsis CRY2
    Xuhong Yu
    Department of Molecular, Cell, and Developmental Biology, University of California Los Angeles, Los Angeles, CA 90095, USA
    Proc Natl Acad Sci U S A 104:7289-94. 2007
    ..Arabidopsis cryptochrome 2 (CRY2) mediates blue light inhibition of hypocotyl elongation and photoperiodic control of floral initiation...
  12. pmc N-terminal domain-mediated homodimerization is required for photoreceptor activity of Arabidopsis CRYPTOCHROME 1
    Yi Sang
    National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China
    Plant Cell 17:1569-84. 2005
    ..Irradiation with blue light modifies the properties of the CNT1 dimer, resulting in a change in CCT1, activating CCT1, and eventually triggering the CRY1 signaling pathway...
  13. ncbi Functional interaction of phytochrome B and cryptochrome 2
    P Mas
    Department of Cell Biology and National Science Foundation Center for Biological Timing, The Scripps Research Institute, La Jolla, California 92037, USA
    Nature 408:207-11. 2000
    ..Cryptochrome 1 (cry1), cryptochrome 2 (cry2) and phototropin are the blue/ultraviolet-A light receptors that have been characterized in Arabidopsis...
  14. ncbi Hierarchical coupling of phytochromes and cryptochromes reconciles stability and light modulation of Arabidopsis development
    M A Mazzella
    IFEVA, Facultad de Agronomia, Universidad de Buenos Aires, Avenida San Martin 4453, 1417 Buenos Aires, Argentina
    Development 128:2291-9. 2001
    ..we show that in Arabidopsis thaliana plants grown under intense white light, coupling of the photoreceptor cryptochrome 2 to developmental processes is broader than previously appreciated...
  15. pmc Circadian clock-regulated expression of phytochrome and cryptochrome genes in Arabidopsis
    R Toth
    Institute of Plant Biology, Biological Research Center of the Hungarian Academy of Sciences, P O Box 521, H 6701 Szeged, Hungary
    Plant Physiol 127:1607-16. 2001
    ..light-regulated expression patterns of the Arabidopsis phytochrome (PHYA to PHYE) and cryptochrome (CRY1 and CRY2) promoters fused to the luciferase (LUC(+)) reporter gene...
  16. ncbi Direct interaction of Arabidopsis cryptochromes with COP1 in light control development
    H Wang
    Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520, USA
    Science 294:154-8. 2001
    ..Arabidopsis has two related cryptochromes (cry1 and cry2) mediating various blue/ultraviolet-A light responses...
  17. pmc Photoreceptors CRYTOCHROME2 and phytochrome B control chromatin compaction in Arabidopsis
    Martijn van Zanten
    Plant Ecophysiology, Institute of Environmental Biology, Utrecht University, 3584 CH Utrecht, The Netherlands
    Plant Physiol 154:1686-96. 2010
    ..We present a model in which chromatin compaction is regulated by the light environment via CRYPTOCHROME2 protein abundance, which is controlled by phytochrome B action...
  18. pmc Network balance via CRY signalling controls the Arabidopsis circadian clock over ambient temperatures
    Peter D Gould
    Institute of Integrative Biology, University of Liverpool, Liverpool, UK
    Mol Syst Biol 9:650. 2013
    ..Our analysis provides a systems-level understanding of period control in the plant circadian oscillator...
  19. doi Lifetimes of Arabidopsis cryptochrome signaling states in vivo
    Vera Herbel
    Department of Plant Physiology and Photobiology, Faculty of Biology, Philipps University, 35032, Marburg, Germany
    Plant J 74:583-92. 2013
    ..Based on the loss of degradation of cry2 after prolonged dark incubation and loss of reversibility of photoactivated cry1 by a pulse of green light, we ..
  20. pmc Light-mediated control of DNA transcription in yeast
    Robert M Hughes
    Department of Biology, Duke University, Durham, NC, United States
    Methods 58:385-91. 2012
    ..Light is dose dependent, inexpensive to apply, easily delivered, and does not interfere with cellular pathways, and thus has significant advantages over chemical systems...
  21. pmc Arabidopsis CRY2 and ZTL mediate blue-light regulation of the transcription factor CIB1 by distinct mechanisms
    Hongtao Liu
    National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai 200032, China
    Proc Natl Acad Sci U S A 110:17582-7. 2013
    ..In Arabidopsis, the photoexcited cryptochrome 2 interacts with the transcription factor CRYPTOCHROME-INTERACTING basic helix-loop-helix 1 (CIB1) to activate ..
  22. doi Strigolactone-regulated hypocotyl elongation is dependent on cryptochrome and phytochrome signaling pathways in Arabidopsis
    Kun Peng Jia
    Key Laboratory of Urban Agriculture South Ministry of Agriculture and School of Agricultural and Biological Sciences, Shanghai Jiaotong University, 800 Dongchuan Road, Shanghai 200240, China
    Mol Plant 7:528-40. 2014
    ..The photoreceptor mutants cry1 cry2, phyA, and phyB are hyposensitive to strigolactone analog GR24 under the respective monochromatic light conditions, ..
  23. pmc Blue-light-dependent interaction of cryptochrome 1 with SPA1 defines a dynamic signaling mechanism
    Hong Li Lian
    Plant Science Institute, School of Agriculture and Biology, Shanghai Jiaotong University, Shanghai, China
    Genes Dev 25:1023-8. 2011
    ..This interaction and consequent dissociation define a dynamic photosensory signaling mechanism...
  24. pmc Nucleolus-tethering system (NoTS) reveals that assembly of photobodies follows a self-organization model
    Yin Liu
    National Key Laboratory of Plant Molecular Genetics, Shanghai Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China
    Mol Biol Cell 25:1366-73. 2014
    ....
  25. pmc Quantitative real-time kinetics of optogenetic proteins CRY2 and CIB1/N using single-molecule tools
    Yi Cui
    Department of Agricultural and Biological Engineering, Bindley Bioscience Center, Purdue University, West Lafayette, IN 47907, United States
    Anal Biochem 458:58-60. 2014
    ..work we evaluate the interaction of two optogenetic protein variants (CIB1, CIBN) with their complementary protein CRY2 by single-molecule tools in cell-free extracts...
  26. pmc An optimized optogenetic clustering tool for probing protein interaction and function
    Amir Taslimi
    Department of Pharmacology, University of Colorado School of Medicine, Aurora, Colorado 80045, USA
    Nat Commun 5:4925. 2014
    The Arabidopsis photoreceptor cryptochrome 2 (CRY2) was previously used as an optogenetic module, allowing spatiotemporal control of cellular processes with light...
  27. pmc Second positive phototropism results from coordinated co-action of the phototropins and cryptochromes
    Craig W Whippo
    Department of Biology, Indiana University, Bloomington, Indiana 47405, USA
    Plant Physiol 132:1499-507. 2003
    ..Based on our results, we hypothesize that phototropins and cryptochromes regulate phototropism by coordinating the balance between stimulation and inhibition of growth of the hypocotyl depending on the fluence rate of blue light...
  28. pmc Cellular metabolites enhance the light sensitivity of Arabidopsis cryptochrome through alternate electron transfer pathways
    Christopher Engelhard
    Fachbereich Physik, Free University, 14195 Berlin, Germany
    Plant Cell 26:4519-31. 2014
    ..Plant cryptochrome (cry1 and cry2) biological activity has been linked to flavin photoreduction via an electron transport chain comprising three ..
  29. pmc The blue light-dependent phosphorylation of the CCE domain determines the photosensitivity of Arabidopsis CRY2
    Qin Wang
    Basic Forestry and Proteomics Research Center, Fujian Agriculture and Forestry University, Fuzhou, China Hunan Province Key Laboratory of Plant Functional Genomics and Developmental Regulation, College of Biology, Hunan University, Changsha 410082, China Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA 90095, USA
    Mol Plant 8:631-43. 2015
    Arabidopsis cryptochrome 2 (CRY2) is a blue light receptor that mediates light inhibition of hypocotyl elongation and long-day promotion of floral initiation...
  30. pmc Negative regulatory roles of DE-ETIOLATED1 in flowering time in Arabidopsis
    Min Young Kang
    Department of Plant Science, Plant Genomics and Breeding Institute, Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 151 921, Korea
    Sci Rep 5:9728. 2015
    ..Thus, we propose that DET1 is a strong repressor of flowering and has a pivotal role in maintaining photoperiod sensitivity in the regulation of flowering time. ..
  31. ncbi HYPERSENSITIVE TO RED AND BLUE 1 and its C-terminal regulatory function control FLOWERING LOCUS T expression
    Xiaojun Kang
    Department of Plant Biology, University of Minnesota, St Paul, MN 55108, USA
    Plant J 52:937-48. 2007
    ..The double mutant of hrb1/cry2 showed a flowering phenotype and an FT expression pattern similar to hrb1 under long-day conditions, suggesting ..
  32. pmc Blue-light dependent ROS formation by Arabidopsis cryptochrome-2 may contribute toward its signaling role
    Nathalie Jourdan
    a UMR 8256 B2A CNRS UPMC IBPS Université Pierre et Marie Curie 9 Paris, France
    Plant Signal Behav 10:e1042647. 2015
    ..Here we extend these observations to show that Atcry2 is translocated from the cytosol to the nucleus in response to blue light illumination, resulting in nuclear ..
  33. pmc Cryptochromes Interact Directly with PIFs to Control Plant Growth in Limiting Blue Light
    Ullas V Pedmale
    Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA Plant Biology Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA Electronic address
    Cell 164:233-45. 2016
    ..For growth under a canopy, where blue light is diminished, CRY1 and CRY2 perceive this change and respond by directly contacting two bHLH transcription factors, PIF4 and PIF5...
  34. ncbi The Blue Light-Dependent Polyubiquitination and Degradation of Arabidopsis Cryptochrome2 Requires Multiple E3 Ubiquitin Ligases
    Qing Liu
    Laboratory of Soil and Plant Molecular Genetics, College of Plant Science, Jilin University, Changchun 130062, China
    Plant Cell Physiol 57:2175-2186. 2016
    ..The Arabidopsis genome encodes two cryptochromes, CRY1 and CRY2, of which CRY2 undergoes blue light-dependent ubiquitination and 26S proteasome-dependent degradation...
  35. pmc Multiple bHLH proteins form heterodimers to mediate CRY2-dependent regulation of flowering-time in Arabidopsis
    Yawen Liu
    National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China
    PLoS Genet 9:e1003861. 2013
    Arabidopsis thaliana cryptochrome 2 (CRY2) mediates light control of flowering time. CIB1 (CRY2-interacting bHLH 1) specifically interacts with CRY2 in response to blue light to activate the transcription of FT (Flowering Locus T)...
  36. pmc A study of the blue-light-dependent phosphorylation, degradation, and photobody formation of Arabidopsis CRY2
    Ze Cheng Zuo
    Institute of Crop Science, Chinese Academy of Agricultural Sciences, Beijing, 100080, China
    Mol Plant 5:726-33. 2012
    Arabidopsis cryptochrome 2 (CRY2) is a blue-light receptor mediating blue-light inhibition of hypocotyl elongation and photoperiodic promotion of floral initiation...
  37. pmc Arabidopsis casein kinase1 proteins CK1.3 and CK1.4 phosphorylate cryptochrome2 to regulate blue light signaling
    Shu Tang Tan
    National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 200032 Shanghai, China
    Plant Cell 25:2618-32. 2013
    ..Blue light is crucial for normal growth of both plants and animals, and blue light receptor cryptochrome2 (CRY2) undergoes blue light-dependent phosphorylation and degradation in planta...
  38. doi Phototropin 1 and cryptochrome action in response to green light in combination with other wavelengths
    Yihai Wang
    Horticultural Sciences Department, University of Florida, 1301 Fifield Hall, PO Box 110690, Gainesville, FL 32611, USA
    Planta 237:225-37. 2013
    ..These findings demonstrate how enriched green environments may adjust RL and BL photomorphogenic responses through both the crys and phot1 receptors, and define a new role for phot1 in stem growth promotion...
  39. pmc Degradation of Arabidopsis CRY2 is regulated by SPA proteins and phytochrome A
    Guido Weidler
    Department of Plant Physiology, Faculty of Biology, Philipps Universitat, D 35032 Marburg, Germany
    Plant Cell 24:2610-23. 2012
    The UV-A/blue light photoreceptor crytochrome2 (cry2) plays a fundamental role in the transition from the vegetative to the reproductive phase in the facultative long-day plant Arabidopsis thaliana...
  40. pmc Phototropins but not cryptochromes mediate the blue light-specific promotion of stomatal conductance, while both enhance photosynthesis and transpiration under full sunlight
    Hernan E Boccalandro
    Instituto de Biología Agrícola de Mendoza, Universidad Nacional de Cuyo and Consejo Nacional de Investigaciones Científicas y Técnicas, 5507 Chacras de Coria, Argentina
    Plant Physiol 158:1475-84. 2012
    ..thaliana) mutants lacking either phototropins 1 and 2 (phot1 and phot2) or cryptochromes 1 and 2 (cry1 and cry2) exposed to a background of red light show severely impaired stomatal opening responses to blue light...
  41. ncbi Cryptochrome blue-light photoreceptors of Arabidopsis implicated in phototropism
    M Ahmad
    Plant Science Institute, Department of Biology, University of Pennsylvania, Philadelphia 19104 6018, USA
    Nature 392:720-3. 1998
    ..HY4 (the gene encoding CRY1) is a member of a small gene family that also encodes a related photoreceptor, CRY2, which shares considerable functional overlap with CRY1...
  42. pmc Analysis of autophosphorylating kinase activities of Arabidopsis and human cryptochromes
    Sezgin Ozgur
    Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599, USA
    Biochemistry 45:13369-74. 2006
    ..To test the generality of light stimulated kinase function of cryptochromes, we purified AtCry1, AtCry2, HsCry1, and HsCry2 and probed them for kinase activity under a variety of conditions...
  43. doi Double loss-of-function mutation in EARLY FLOWERING 3 and CRYPTOCHROME 2 genes delays flowering under continuous light but accelerates it under long days and short days: an important role for Arabidopsis CRY2 to accelerate flowering time in continuous lig
    Rim Nefissi
    Gene Research Center, University of Tsukuba, Tennodai 1 1 1, Tsukuba, Ibaraki 305 8572, Japan
    J Exp Bot 62:2731-44. 2011
    ..Genetic analysis indicated that sel20 was a new deletion allele of a mutation in the blue light receptor, CRY2. A late-flowering phenotype and decrease of FT expression in the elf3;sel20 double mutant was obvious under LL but ..
  44. pmc Cryptochrome 2 and phototropin 2 regulate resistance protein-mediated viral defense by negatively regulating an E3 ubiquitin ligase
    Rae Dong Jeong
    Department of Plant Pathology, University of Kentucky, Lexington, KY 40546, USA
    Proc Natl Acad Sci U S A 107:13538-43. 2010
    ..Exposure to darkness or blue-light induces degradation of CRY2, and in turn HRT, resulting in susceptibility...
  45. doi Blue-light-independent activity of Arabidopsis cryptochromes in the regulation of steady-state levels of protein and mRNA expression
    Yue Jun Yang
    Bioenergy and Biomaterial Research Center, Hunan University, Changsha 410082, China
    Mol Plant 1:167-77. 2008
    ..These results support a hypothesis that, in addition to their blue-light-specific functions, cryptochromes also play roles in the control of gene expression mediated by the red/far-red-light receptor phytochromes...
  46. ncbi Flowering of Arabidopsis cop1 mutants in darkness
    Mayu Nakagawa
    Division of Biological Sciences, Graduate School of Science, Hokkaido University, N10 W8, Sapporo, 060 0810 Japan
    Plant Cell Physiol 45:398-406. 2004
    ..Double mutants of cop1-6 and each of the late-flowering mutations cry2-1, gi-2, co-1, and ld-1 flowered in darkness...
  47. pmc Distinct light-initiated gene expression and cell cycle programs in the shoot apex and cotyledons of Arabidopsis
    Enrique Lopez-Juez
    School of Biological Sciences, Royal Holloway, University of London, Egham, Surrey TW20 0EX, United Kingdom
    Plant Cell 20:947-68. 2008
    ..These data provide the basis for reconstruction of the regulatory networks for light-regulated meristem, leaf, and cotyledon development...
  48. pmc Distinct light and clock modulation of cytosolic free Ca2+ oscillations and rhythmic CHLOROPHYLL A/B BINDING PROTEIN2 promoter activity in Arabidopsis
    Xiaodong Xu
    Department of Biological Sciences, Vanderbilt University, Nashville, Tenessee 37235, USA
    Plant Cell 19:3474-90. 2007
    ..Blue light signaling occurs through the redundant action of CRYPTOCHROME1 (CRY1) and CRY2. Blue light also increases the basal level of [Ca(2+)](cyt), and this response requires PHYB, CRY1, and CRY2...
  49. pmc From The Cover: A role for Arabidopsis cryptochromes and COP1 in the regulation of stomatal opening
    Jian Mao
    National Key Laboratory of Plant Molecular Genetics, Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 300 Fenglin Road, Shanghai 200032, China
    Proc Natl Acad Sci U S A 102:12270-5. 2005
    ..Arabidopsis CRY (CRY1 and CRY2) functions through negatively regulating constitutive photomorphogenic (COP) 1, a repressor of photomorphogenesis...
  50. ncbi Cryptochrome photoreceptors cry1 and cry2 antagonistically regulate primary root elongation in Arabidopsis thaliana
    Roberto C Canamero
    Universite de Paris VI, PCMP, Casier 156, 4 place Jussieu, 75005 Paris, France
    Planta 224:995-1003. 2006
    ..Here we report the effect of cry1 and cry2 blue light receptors on primary root growth in Arabidopsis thaliana seedlings, through analysis of both ..
  51. pmc CRYPTOCHROME2 in vascular bundles regulates flowering in Arabidopsis
    Motomu Endo
    Laboratory of Plant Physiology, Graduate School of Science, Kyoto University, Kitashirakawa Oiwake cho, Sakyo ku, Kyoto 606 8502, Japan
    Plant Cell 19:84-93. 2007
    ..In Arabidopsis thaliana, a blue/UV-A photoreceptor, CRYPTOCHROME 2 (cry2), and a red/far-red photoreceptor, PHYTOCHROME B (phyB), are two major photoreceptors that control ..