ELF3

Summary

Gene Symbol: ELF3
Description: hydroxyproline-rich glycoprotein family protein
Alias: EARLY FLOWERING 3, F17H15.25, PYK20
Species: thale cress

Top Publications

  1. ncbi The Arabidopsis ELF3 gene regulates vegetative photomorphogenesis and the photoperiodic induction of flowering
    M T Zagotta
    Institute of Molecular Biology, University of Oregon, Eugene 97403, USA
    Plant J 10:691-702. 1996
  2. pmc Temporal repression of core circadian genes is mediated through EARLY FLOWERING 3 in Arabidopsis
    Laura E Dixon
    Centre of Systems Biology at Edinburgh, University of Edinburgh, Edinburgh, Midlothian EH9 3JD, UK
    Curr Biol 21:120-5. 2011
  3. pmc Ambient temperature response establishes ELF3 as a required component of the core Arabidopsis circadian clock
    Bryan Thines
    Plant Gene Expression Center, US Department of Agriculture Agricultural Research Service, Albany, CA 94710, USA
    Proc Natl Acad Sci U S A 107:3257-62. 2010
  4. pmc COP1 and ELF3 control circadian function and photoperiodic flowering by regulating GI stability
    Jae Woong Yu
    Department of Plant Science and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151 921, Korea
    Mol Cell 32:617-30. 2008
  5. ncbi ELF4 is a phytochrome-regulated component of a negative-feedback loop involving the central oscillator components CCA1 and LHY
    Elise A Kikis
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA
    Plant J 44:300-13. 2005
  6. pmc The TIME FOR COFFEE gene maintains the amplitude and timing of Arabidopsis circadian clocks
    Anthony Hall
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom
    Plant Cell 15:2719-29. 2003
  7. pmc ELF3 modulates resetting of the circadian clock in Arabidopsis
    M F Covington
    Institute of Molecular Biology, University of Oregon, Eugene, Oregon 97403, USA
    Plant Cell 13:1305-15. 2001
  8. pmc ELF3 encodes a circadian clock-regulated nuclear protein that functions in an Arabidopsis PHYB signal transduction pathway
    X L Liu
    Institute of Molecular Biology, University of Oregon, Eugene, Oregon 97403, USA
    Plant Cell 13:1293-304. 2001
  9. pmc Independent action of ELF3 and phyB to control hypocotyl elongation and flowering time
    J W Reed
    University of North Carolina, Biology Department, CB 3280, Coker Hall, Chapel Hill, North Carolina 27599 3280, USA
    Plant Physiol 122:1149-60. 2000
  10. pmc Quantitative Variation in Responses to Root Spatial Constraint within Arabidopsis thaliana
    Bindu Joseph
    Department of Plant Sciences, University of California, Davis, California 95616 Bayer Crop Science, Crop Genetics Department, Morrisville, North Carolina 27560
    Plant Cell 27:2227-43. 2015

Research Grants

Scientific Experts

  • Toshinori Kinoshita
  • Jason Reed
  • Sylvie Pouteau
  • M Koornneef
  • Seth J Davis
  • Eva Herrero
  • Muhammad Usman Anwer
  • Andrew J Millar
  • Dmitri A Nusinow
  • Nora Bujdoso
  • Elsebeth Kolmos
  • He Huang
  • Chang Quan Wang
  • Bindu Joseph
  • Min Young Kang
  • Anja Raschke
  • Cristina Nieto
  • Mathew S Box
  • Mani Kant Choudhary
  • Seth Jon Davis
  • Kanae Niinuma
  • Ferenc Nagy
  • Soledad Francisca Undurraga
  • Sheen X Lu
  • Nam Chon Paek
  • Laura E Dixon
  • Rim Nefissi
  • M Paula Coluccio
  • George Coupland
  • Jose M Jimenez-Gomez
  • David E Somers
  • Mayu Nakagawa
  • Tsuyoshi Mizoguchi
  • Atsushi Oda
  • Kana Miyata
  • Bryan Thines
  • Barbara Strasser
  • Riichiro Yoshida
  • Jae Woong Yu
  • Zhaojun Ding
  • M F Covington
  • X L Liu
  • Elise A Kikis
  • Woe Yeon Kim
  • Rebecca Bindbeutel
  • Bradley S Evans
  • Michael J Naldrett
  • Jessica Goldsworthy
  • Meng Chen
  • Anthony Hall
  • Chan Yul Yoo
  • Allison Tielking
  • Sophie Alvarez
  • Min Ni
  • Byoung Doo Lee
  • Hye Young Kwon
  • Lei Wang
  • Seong Jeon Yoo
  • D Marc Jones
  • Sebastian Becker
  • Marcel Quint
  • Xiaodong Sun
  • Carla Ibanez
  • Mostafa Khoshhal Sarmast
  • Katja E Jaeger
  • Mirela Domijan
  • Salome Prat
  • Asif Khan Khattak
  • Jean Michel Davière
  • Hirofumi Nakagami
  • Vadir López-Salmerón
  • Carolin Delker
  • Timothy J Hearn
  • Emma L Sedivy
  • Soo Cheul Yoo
  • Jana Trenner
  • James C W Locke
  • Alex A R Webb
  • Annemarie Glöckner
  • Bernhard Saal
  • Lillian Lau
  • Jishan Jiang
  • Yoo Sun Noh
  • Jung Nam Cho
  • Kristian Karsten Ullrich
  • Kathrin Denk
  • Philip A Wigge
  • Yuko Nomura
  • Alastair Grant
  • B Emma Huang

Detail Information

Publications36

  1. ncbi The Arabidopsis ELF3 gene regulates vegetative photomorphogenesis and the photoperiodic induction of flowering
    M T Zagotta
    Institute of Molecular Biology, University of Oregon, Eugene 97403, USA
    Plant J 10:691-702. 1996
    ..The early-flowering 3 (elf3) mutant of Arabidopsis, which is insensitive to photoperiod with regard to floral initiation has been characterized ..
  2. pmc Temporal repression of core circadian genes is mediated through EARLY FLOWERING 3 in Arabidopsis
    Laura E Dixon
    Centre of Systems Biology at Edinburgh, University of Edinburgh, Edinburgh, Midlothian EH9 3JD, UK
    Curr Biol 21:120-5. 2011
    ..b>EARLY FLOWERING 3 (ELF3) has been implicated as a repressor of light signaling to the clock [2, 3] and, paradoxically, as an ..
  3. pmc Ambient temperature response establishes ELF3 as a required component of the core Arabidopsis circadian clock
    Bryan Thines
    Plant Gene Expression Center, US Department of Agriculture Agricultural Research Service, Albany, CA 94710, USA
    Proc Natl Acad Sci U S A 107:3257-62. 2010
    ..External light and temperature cues set the core molecular oscillator to local conditions. In Arabidopsis, EARLY FLOWERING 3 (ELF3) is thought to act as an evening-specific repressor of light signals to the clock, thus serving a ..
  4. pmc COP1 and ELF3 control circadian function and photoperiodic flowering by regulating GI stability
    Jae Woong Yu
    Department of Plant Science and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul 151 921, Korea
    Mol Cell 32:617-30. 2008
    ..Blue-light-sensing cryptochromes, the E3 ubiquitin-ligase COP1, and clock-associated proteins ELF3 and GI regulate this process, although the regulatory link between them is unclear...
  5. ncbi ELF4 is a phytochrome-regulated component of a negative-feedback loop involving the central oscillator components CCA1 and LHY
    Elise A Kikis
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA
    Plant J 44:300-13. 2005
    ..wild-type and mutant seedlings to examine the role of these oscillator components, and to determine the function of ELF3 and ELF4 in their light-regulated expression...
  6. pmc The TIME FOR COFFEE gene maintains the amplitude and timing of Arabidopsis circadian clocks
    Anthony Hall
    Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, United Kingdom
    Plant Cell 15:2719-29. 2003
    ..to late subjective night, when human activity may require coffee, in contrast to the function of EARLY-FLOWERING3 (ELF3) in the late day to early night...
  7. pmc ELF3 modulates resetting of the circadian clock in Arabidopsis
    M F Covington
    Institute of Molecular Biology, University of Oregon, Eugene, Oregon 97403, USA
    Plant Cell 13:1305-15. 2001
    The Arabidopsis early flowering 3 (elf3) mutation causes arrhythmic circadian output in continuous light, but there is some evidence of clock function in darkness...
  8. pmc ELF3 encodes a circadian clock-regulated nuclear protein that functions in an Arabidopsis PHYB signal transduction pathway
    X L Liu
    Institute of Molecular Biology, University of Oregon, Eugene, Oregon 97403, USA
    Plant Cell 13:1293-304. 2001
    ..Loss-of-function mutations in the Arabidopsis EARLY FLOWERING 3 (ELF3) and PHYTOCHROME B (PHYB) genes cause early flowering and influence the activity of circadian clock-..
  9. pmc Independent action of ELF3 and phyB to control hypocotyl elongation and flowering time
    J W Reed
    University of North Carolina, Biology Department, CB 3280, Coker Hall, Chapel Hill, North Carolina 27599 3280, USA
    Plant Physiol 122:1149-60. 2000
    ..In a screen for Arabidopsis mutants with phenotypes similar to those of phyB mutants, we isolated two new elf3 mutants...
  10. pmc Quantitative Variation in Responses to Root Spatial Constraint within Arabidopsis thaliana
    Bindu Joseph
    Department of Plant Sciences, University of California, Davis, California 95616 Bayer Crop Science, Crop Genetics Department, Morrisville, North Carolina 27560
    Plant Cell 27:2227-43. 2015
    ..polygenic trait and, using quantitative validation studies, we showed that natural variation in EARLY FLOWERING3 (ELF3) controls the link between root constraint and altered shoot growth...
  11. pmc Quantitative Circadian Phosphoproteomic Analysis of Arabidopsis Reveals Extensive Clock Control of Key Components in Physiological, Metabolic, and Signaling Pathways
    Mani Kant Choudhary
    From the Division of Integrative Biosciences and Biotechnology, POSTECH, Hyojadong, Pohang, Kyungbuk, 790 784, Republic of Korea
    Mol Cell Proteomics 14:2243-60. 2015
    ..We show that removal of this phosphorylatable site diminishes interaction with early flowering3 (ELF3), a key partner in a tripartite evening complex required for circadian cycling...
  12. pmc Negative regulatory roles of DE-ETIOLATED1 in flowering time in Arabidopsis
    Min Young Kang
    Department of Plant Science, Plant Genomics and Breeding Institute, Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 151 921, Korea
    Sci Rep 5:9728. 2015
    ..Thus, we propose that DET1 is a strong repressor of flowering and has a pivotal role in maintaining photoperiod sensitivity in the regulation of flowering time. ..
  13. pmc The Transcriptional Regulator BBX19 Promotes Hypocotyl Growth by Facilitating COP1-Mediated EARLY FLOWERING3 Degradation in Arabidopsis
    Chang Quan Wang
    Department of Plant Biology, University of California, Davis, California 95616
    Plant Cell 27:1128-39. 2015
    ..function of BBX19 is dependent on the E3 ubiquitin ligase CONSTITUTIVE PHOTOMORPHOGENIC1 (COP1), EARLY FLOWERING3 (ELF3), and PHYTOCHROME-INTERACTING FACTOR4 (PIF4) and PIF5...
  14. doi ELF3-PIF4 interaction regulates plant growth independently of the Evening Complex
    Cristina Nieto
    Departamento Genética Molecular de Plantas, Centro Nacional de Biotecnologia CSIC, Campus de Cantoblanco, Darwin 3, 28049 Madrid, Spain
    Curr Biol 25:187-93. 2015
    ..During early night, PIF4 and PIF5 transcription is repressed by the Evening Complex (EC) proteins EARLY FLOWERING3 (ELF3), EARLY FLOWERING4 (ELF4), and LUX ARRHYTHMO (LUX)...
  15. doi ELF3 controls thermoresponsive growth in Arabidopsis
    Mathew S Box
    The Sainsbury Laboratory, University of Cambridge, Cambridge CB2 1LR, UK
    Curr Biol 25:194-9. 2015
    ..We find that the transcriptional regulator EARLY FLOWERING3 (ELF3) controls elongation growth in response to temperature...
  16. pmc Natural variants of ELF3 affect thermomorphogenesis by transcriptionally modulating PIF4-dependent auxin response genes
    Anja Raschke
    Department of Molecular Signal Processing, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120, Halle, Saale, Germany
    BMC Plant Biol 15:197. 2015
    ..Here, we exploited natural variation for thermo-responsive growth in Arabidopsis thaliana using quantitative trait locus (QTL) analysis...
  17. pmc Natural variation reveals that intracellular distribution of ELF3 protein is associated with function in the circadian clock
    Muhammad Usman Anwer
    Department of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, Cologne, Germany
    elife 3:. 2014
    ..Extensive variation led us to identify EARLY FLOWERING3 (ELF3) as a major quantitative trait locus (QTL)...
  18. pmc PCH1 integrates circadian and light-signaling pathways to control photoperiod-responsive growth in Arabidopsis
    He Huang
    Donald Danforth Plant Science Center, St Louis, United States
    elife 5:e13292. 2016
    ..Thus, PCH1 is a new factor that regulates photoperiod-responsive growth by integrating the clock with light perception pathways through modulating daily phyB-signaling. ..
  19. doi Double loss-of-function mutation in EARLY FLOWERING 3 and CRYPTOCHROME 2 genes delays flowering under continuous light but accelerates it under long days and short days: an important role for Arabidopsis CRY2 to accelerate flowering time in continuous lig
    Rim Nefissi
    Gene Research Center, University of Tsukuba, Tennodai 1 1 1, Tsukuba, Ibaraki 305 8572, Japan
    J Exp Bot 62:2731-44. 2011
    ..The circadian clock plays pivotal roles in this process. In Arabidopsis, LHY, CCA1, ELF3, and other clock proteins play major roles in maintaining circadian rhythms...
  20. pmc Independent roles for EARLY FLOWERING 3 and ZEITLUPE in the control of circadian timing, hypocotyl length, and flowering time
    Woe Yeon Kim
    Department of Plant Cellular and Molecular Biology, Plant Biotechnology Center, Ohio State University, Columbus, OH 43210, USA
    Plant Physiol 139:1557-69. 2005
    ..b>EARLY FLOWERING 3 (ELF3) is a novel protein of unknown biochemical function...
  21. pmc A reduced-function allele reveals that EARLY FLOWERING3 repressive action on the circadian clock is modulated by phytochrome signals in Arabidopsis
    Elsebeth Kolmos
    Max Planck Institute for Plant Breeding Research, 50829 Cologne, Germany
    Plant Cell 23:3230-46. 2011
    Arabidopsis thaliana EARLY FLOWERING3 (ELF3) is essential for the generation of circadian rhythms...
  22. pmc CCA1 and ELF3 Interact in the control of hypocotyl length and flowering time in Arabidopsis
    Sheen X Lu
    University of California, Department of Molecular, Cell, and Developmental Biology, Los Angeles, California 90095, USA
    Plant Physiol 158:1079-88. 2012
    ..EARLY FLOWERING3 (ELF3) modulates light input to the clock and is also postulated to be part of the clock mechanism...
  23. pmc EARLY FLOWERING4 recruitment of EARLY FLOWERING3 in the nucleus sustains the Arabidopsis circadian clock
    Eva Herrero
    Max Planck Institute for Plant Breeding Research, D 50829 Cologne, Germany
    Plant Cell 24:428-43. 2012
    ..This phenotype is shared with both elf3 and lux...
  24. pmc Background-dependent effects of polyglutamine variation in the Arabidopsis thaliana gene ELF3
    Soledad Francisca Undurraga
    Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 109:19363-7. 2012
    ..thaliana to dissect the phenotypic consequences of natural variation in the polyQ tract encoded by EARLY FLOWERING 3 (ELF3), a key developmental gene...
  25. pmc Genetic mapping of natural variation in a shade avoidance response: ELF3 is the candidate gene for a QTL in hypocotyl growth regulation
    M Paula Coluccio
    IFEVA, Facultad de Agronomia, Universidad de Buenos Aires y Consejo Nacional de Investigaciones Científicas y Técnicas, Av San Martin 4453, C1417DSE, Ciudad de Buenos Aires, Argentina
    J Exp Bot 62:167-76. 2011
    ..Genetic and quantitative complementation analyses demonstrated that ELF3 is the most likely candidate gene underlying natural variation at EODINDEX1...
  26. ncbi The early-flowering mutant efs is involved in the autonomous promotion pathway of Arabidopsis thaliana
    W J Soppe
    Laboratory of Genetics, Wageningen University, Dreijenlaan 2, Wageningen, The Netherlands
    Development 126:4763-70. 1999
    ..By comparing the length of the juvenile and adult phases of vegetative growth for wild-type, efs and the double mutant plants, it is apparent that efs mainly reduces the length of the adult phase...
  27. ncbi Isolation of a gene from Arabidopsis thaliana related to nematode feeding structures
    P S Puzio
    Institut für Phytopathologie, Universitat Kiel, Germany
    Gene 239:163-72. 1999
    ..This tagged gene, designated pyk20, encodes a transcript of 2.6 kb...
  28. ncbi Circadian rhythm of circumnutation in inflorescence stems of Arabidopsis
    Kanae Niinuma
    Plant Science Center, RIKEN, 1 7 22 Suehiro, Tsurumi, Yokohama, Kanagawa, 230 0045 Japan
    Plant Cell Physiol 46:1423-7. 2005
    ..toc1 appears to shorten the period and elf3 causes an arrhythmic phenotype in circumnutation speed in LL, suggesting that a common circadian clock may control ..
  29. pmc TIME FOR COFFEE encodes a nuclear regulator in the Arabidopsis thaliana circadian clock
    Zhaojun Ding
    Department of Plant Developmental Biology, Max Planck Institute for Plant Breeding Research, Cologne D 50829, Germany
    Plant Cell 19:1522-36. 2007
    ..Neither its abundance nor its cellular distribution was found to be clock regulated. We suggest that TIC encodes a nucleus-acting clock regulator working close to the central oscillator...
  30. pmc Diversification of photoperiodic response patterns in a collection of early-flowering mutants of Arabidopsis
    Sylvie Pouteau
    UR Biologie Cellulaire, INRA, F78026 Versailles, France
    Plant Physiol 148:1465-73. 2008
    ..Furthermore, the frequency of circadian defects in mutants with normal photoperiodic responses suggested that the circadian clock may regulate the number of leaves independently of its effect on daylength perception...
  31. doi A complementary role for ELF3 and TFL1 in the regulation of flowering time by ambient temperature
    Barbara Strasser
    Fundacion Instituto Leloir, Universidad de Buenos Aires, Argentina
    Plant J 58:629-40. 2009
    ..regulates flowering by two genetically distinguishable pathways, one requiring TFL1 and another requiring ELF3. The delay in flowering time observed at lower temperatures was partially suppressed in single elf3 and tfl1 ..
  32. doi Possible role of early flowering 3 (ELF3) in clock-dependent floral regulation by short vegetative phase (SVP) in Arabidopsis thaliana
    Riichiro Yoshida
    Gene Research Center, University of Tsukuba, Tennodai 1 1 1, Tsukuba, Ibaraki 305 8572, Japan
    New Phytol 182:838-50. 2009
    ..Mutations in the clock gene early flowering 3 (ELF3) were identified as suppressors...
  33. pmc Network analysis identifies ELF3 as a QTL for the shade avoidance response in Arabidopsis
    Jose M Jimenez-Gomez
    Department of Plant Biology, College of Biological Sciences, University of California Davis, Davis, California, United States of America
    PLoS Genet 6:e1001100. 2010
    ..This novel network analysis detected EARLY FLOWERING 3 (ELF3; AT2G25930) as the most likely candidate gene affecting the shade avoidance response in our population...
  34. pmc The ELF4-ELF3-LUX complex links the circadian clock to diurnal control of hypocotyl growth
    Dmitri A Nusinow
    Section of Cell and Developmental Biology, Division of Biological Sciences, University of California San Diego 9500 Gilman Drive, La Jolla, California 92093 0130, USA
    Nature 475:398-402. 2011
    ..Here we identify a protein complex (called the evening complex)--composed of the proteins encoded by EARLY FLOWERING 3 (ELF3), ELF4 and the transcription-factor-encoding gene LUX ARRHYTHMO (LUX; also known as PHYTOCLOCK 1)--..
  35. doi FLOWERING LOCUS T regulates stomatal opening
    Toshinori Kinoshita
    Division of Biological Science, Graduate School of Science, Nagoya University, Nagoya, Aichi 464 8602, Japan
    Curr Biol 21:1232-8. 2011
    ..phenotype in phot1 phot2) 1-1 mutant of Arabidopsis thaliana and showed that scs1-1 carries a novel null early flowering 3 (elf3) allele in a phot1 phot2 background...

Research Grants1

  1. SHY2/IAA3 in auxin regulation of plant development
    Jason Reed; Fiscal Year: 2006
    ..These experiments will help us understand how auxin regulates development in a model system, and will in the future allow manipulation of morphology of crop plants in ways beneficial to human health. ..